31 results on '"Reuver, Philip"'
Number of results to display per page
Search Results
2. Towards Equal Access to Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy and Survival in Patients with Isolated Colorectal Peritoneal Metastases:A Nationwide Population-Based Study
- Author
-
van der Ven, Roos G.F.M., van den Heuvel, Teun B.M., Rovers, Koen P.B., Nienhuijs, Simon W., Boerma, Djamila, van Grevenstein, Wilhelmina M.U., Hemmer, Patrick H.J., Kok, Niels F.M., Madsen, Eva V.E., de Reuver, Philip, Tuynman, Jurriaan B., van Erning, Felice N., de Hingh, Ignace H.J.T., van der Ven, Roos G.F.M., van den Heuvel, Teun B.M., Rovers, Koen P.B., Nienhuijs, Simon W., Boerma, Djamila, van Grevenstein, Wilhelmina M.U., Hemmer, Patrick H.J., Kok, Niels F.M., Madsen, Eva V.E., de Reuver, Philip, Tuynman, Jurriaan B., van Erning, Felice N., and de Hingh, Ignace H.J.T.
- Abstract
Background: Before 2016, patients with isolated synchronous colorectal peritoneal metastases (PMCRC) diagnosed in expert centers had a higher odds of undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) and better overall survival (OS) than those diagnosed in referring centers. Nationwide efforts were initiated to increase awareness and improve referral networks. Methods: This nationwide study aimed to evaluate whether the between-center differences in odds of undergoing CRS-HIPEC and OS have reduced since these national efforts were initiated. All patients with isolated synchronous PMCRC diagnosed between 2009 and 2021 were identified from the Netherlands Cancer Registry. Associations between hospital of diagnosis and the odds of undergoing CRS-HIPEC, as well as OS, were assessed using multilevel multivariable regression analyses for two periods (2009–2015 and 2016–2021). Results: In total, 3948 patients were included. The percentage of patients undergoing CRS-HIPEC increased from 17.2% in 2009–2015 (25.4% in expert centers, 16.5% in referring centers), to 23.4% in 2016–2021 (30.2% in expert centers, 22.6% in referring centers). In 2009–2015, compared with diagnosis in a referring center, diagnosis in a HIPEC center showed a higher odds of undergoing CRS-HIPEC (odds ratio [OR] 1.64, 95% confidence interval [CI] 1.02–2.67) and better survival (hazard ratio [HR] 0.80, 95% CI 0.66–0.96). In 2016–2021, there were no differences in the odds of undergoing CRS-HIPEC between patients diagnosed in HIPEC centers versus referring centers (OR 1.27, 95% CI 0.76–2.13) and survival (HR 1.00, 95% CI 0.76–1.32). Conclusion: Previously observed differences in odds of undergoing CRS-HIPEC were no longer present. Increased awareness and the harmonization of treatment for PMCRC may have contributed to equal access to care and a similar chance of survival at a national
- Published
- 2024
3. An observational cohort of patients with colorectal peritoneal metastases or pseudomyxoma peritonei treated with CRS-HIPEC: Development and first results of the Dutch CRS-HIPEC quality registry
- Author
-
Zorgeenheid Kinderchirurgie Medisch, MS CGO, Cancer, van Erning, Felice N., van den Heuvel, Teun B.M., Sijtsma, Femke P.C., Boerma, Djamila, Brandt-Kerkhof, Alexandra R.M., Bremers, André J., van Duyn, Eino B., van Grevenstein, Helma M.U., Hemmer, Patrick H.J., Kok, Niels F.M., Madsen, Eva, de Reuver, Philip R., Wiezer, René J., Witkamp, Arjan J., Nienhuijs, Simon W., Poelmann, Floris B., Tuynman, Jurriaan B., Been, Lucas B., Rovers, Koen P., de Hingh, Ignace H.J.T., Zorgeenheid Kinderchirurgie Medisch, MS CGO, Cancer, van Erning, Felice N., van den Heuvel, Teun B.M., Sijtsma, Femke P.C., Boerma, Djamila, Brandt-Kerkhof, Alexandra R.M., Bremers, André J., van Duyn, Eino B., van Grevenstein, Helma M.U., Hemmer, Patrick H.J., Kok, Niels F.M., Madsen, Eva, de Reuver, Philip R., Wiezer, René J., Witkamp, Arjan J., Nienhuijs, Simon W., Poelmann, Floris B., Tuynman, Jurriaan B., Been, Lucas B., Rovers, Koen P., and de Hingh, Ignace H.J.T.
- Published
- 2024
4. Towards Equal Access to Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy and Survival in Patients with Isolated Colorectal Peritoneal Metastases: A Nationwide Population-Based Study
- Author
-
MS CGO, Cancer, van der Ven, Roos G.F.M., van den Heuvel, Teun B.M., Rovers, Koen P.B., Nienhuijs, Simon W., Boerma, Djamila, van Grevenstein, Wilhelmina M.U., Hemmer, Patrick H.J., Kok, Niels F.M., Madsen, Eva V.E., de Reuver, Philip, Tuynman, Jurriaan B., van Erning, Felice N., de Hingh, Ignace H.J.T., MS CGO, Cancer, van der Ven, Roos G.F.M., van den Heuvel, Teun B.M., Rovers, Koen P.B., Nienhuijs, Simon W., Boerma, Djamila, van Grevenstein, Wilhelmina M.U., Hemmer, Patrick H.J., Kok, Niels F.M., Madsen, Eva V.E., de Reuver, Philip, Tuynman, Jurriaan B., van Erning, Felice N., and de Hingh, Ignace H.J.T.
- Published
- 2024
5. Development of a prediction model for recurrence in patients with colorectal peritoneal metastases undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy
- Author
-
Dietz, Michelle V, Hannink, Gerjon, Said, Ibrahim, van der Zant, Femke A, van de Vlasakker, Vincent C J, Brandt-Kerkhof, Alexandra R M, Verhoef, Cornelis, Bremers, Andreas J A, de Wilt, Johannes H W, Hemmer, Patrick H J, de Hingh, Ignace H J T, de Reuver, Philip R, Madsen, Eva V E, Dietz, Michelle V, Hannink, Gerjon, Said, Ibrahim, van der Zant, Femke A, van de Vlasakker, Vincent C J, Brandt-Kerkhof, Alexandra R M, Verhoef, Cornelis, Bremers, Andreas J A, de Wilt, Johannes H W, Hemmer, Patrick H J, de Hingh, Ignace H J T, de Reuver, Philip R, and Madsen, Eva V E
- Abstract
INTRODUCTION: Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) improves survival outcomes for selected patients with colorectal peritoneal metastases (PM), but recurrence rates are high. The aim of this study was to develop a tool to predict recurrence in patients with colorectal PM that undergo CRS-HIPEC.MATERIALS AND METHODS: For this retrospective cohort study, data of patients that underwent CRS-HIPEC for colorectal PM from four Dutch HIPEC centers were used. Exclusion criteria were perioperative systemic therapy and peritoneal cancer index (PCI) ≥20. Nine previously identified factors were considered as predictors: gender, age, primary tumor characteristics (location, nodal stage, differentiation, and mutation status), synchronous liver metastases, preoperative Carcino-Embryonal Antigen (CEA), and peritoneal cancer index (PCI). The prediction model was developed using multivariable Cox regression and validated internally using bootstrapping. The performance of the model was evaluated by discrimination and calibration.RESULTS: In total, 408 patients were included. During the follow-up, recurrence of disease occurred in 318 patients (78%). Significant predictors of recurrence were PCI (HR 1.075, 95% CI 1.044-1.108) and primary tumor location (left sided HR 0.719, 95% CI 0.550-0.939). The prediction model for recurrence showed fair discrimination with a C-index of 0.64 (95% CI 0.62, 0.66) after internal validation. The model was well-calibrated with good agreement between the predicted and observed probabilities.CONCLUSION: We developed a prediction tool that could aid in the prediction of recurrence in patients with colorectal PM who undergo CRS-HIPEC.
- Published
- 2024
6. Referral rate of patients with incidental gallbladder cancer and survival:outcomes of a multicentre retrospective study
- Author
-
van Dooren, Mike, de Savornin Lohman, Elise A.J., van der Post, Rachel S., Erdmann, Joris I., Hoogwater, Frederik J.H., Koerkamp, Bas Groot, van den Boezem, Peter B., de Reuver, Philip R., van Dooren, Mike, de Savornin Lohman, Elise A.J., van der Post, Rachel S., Erdmann, Joris I., Hoogwater, Frederik J.H., Koerkamp, Bas Groot, van den Boezem, Peter B., and de Reuver, Philip R.
- Abstract
Background: Treatment outcomes of incidental gallbladder cancer generally stem from tertiary referral centres, while many patients are initially diagnosed and managed in secondary care centres. Referral patterns of patients with incidental gallbladder cancer are poorly reported. This study aimed to evaluate incidental gallbladder cancer treatment in secondary centres, rates of referral to tertiary centres and its impact on survival. Methods: Medical records of patients with incidental gallbladder cancer diagnosed between 2000 and 2019 in 27 Dutch secondary centres were retrospectively reviewed. Patient characteristics, surgical treatment, tumour characteristics, referral pattern and survival were assessed. Predictors for overall survival were determined using multivariable Cox regression. Results: In total, 382 patients with incidental gallbladder cancer were included. Of 243 patients eligible for re-resection (pT1b–pT3, M0), 131 (53.9%) were referred to a tertiary centre. The reason not to refer, despite indication for re-resection, was not documented for 52 of 112 non-referred patients (46.4%). In total, 98 patients underwent additional surgery with curative intent (40.3%), 12 of these in the secondary centre. Median overall survival was 33 months (95% c.i. 24 to 42 months) in referred patients versus 17 months (95% c.i. 3 to 31 months) in the non-referred group (P = 0.019). Referral to a tertiary centre was independently associated with improved survival after correction for age, ASA classification, tumour stage and resection margin (HR 0.60, 95% c.i. 0.38 to 0.97; P = 0.037). Conclusion: Poor incidental gallbladder cancer referral rates were associated with worse survival. Age, performance status, resection margin or tumour stage should not preclude referral of a patient with incidental gallbladder cancer to a tertiary centre.
- Published
- 2024
7. The diagnostic value of staging laparoscopy in gallbladder cancer:a nationwide cohort study
- Author
-
van Dooren, Mike, de Savornin Lohman, Elise A.J., Brekelmans, Eva, Vissers, Pauline A.J., Erdmann, Joris I., Braat, Andries E., Hagendoorn, Jeroen, Daams, Freek, van Dam, Ronald M., de Boer, Marieke T., van den Boezem, Peter B., Koerkamp, Bas Groot, de Reuver, Philip R., van Dooren, Mike, de Savornin Lohman, Elise A.J., Brekelmans, Eva, Vissers, Pauline A.J., Erdmann, Joris I., Braat, Andries E., Hagendoorn, Jeroen, Daams, Freek, van Dam, Ronald M., de Boer, Marieke T., van den Boezem, Peter B., Koerkamp, Bas Groot, and de Reuver, Philip R.
- Abstract
Background: Disseminated disease (DD) is often found at (re-)exploration in gallbladder cancer (GBC) patients. We aimed to assess the yield of staging laparoscopy (SL) and identify predictors for DD. Methods: This retrospective study included patients from all Dutch academic centres with primary GBC (pGBC) and incidentally diagnosed GBC (iGBC) planned for (re-)resection. The yield of SL was determined. In iGBC, predictive factors for DD were assessed. Results: In total, 290 patients were included. Of 183 included pGBC patients, 143 underwent laparotomy without SL, and 42 (29%) showed DD perioperatively. SL, conducted in 40 patients, identified DD in eight. DD was found in nine of 32 patients who underwent laparotomy after SL. Of 107 included iGBC patients, 100 underwent laparotomy without SL, and 19 showed DD perioperatively. SL, conducted in seven patients, identified DD in one. Cholecystitis (OR = 4.25; 95% CI 1.51–11.91) and primary R1/R2 resection (OR = 3.94; 95% CI 1.39–11.19) were independent predictive factors for DD. Conclusions: In pGBC patients, SL may identify DD in up to 20% of patients and should be part of standard management. In iGBC patients, SL is indicated after primary resection for cholecystitis and after initial R1/R2 resection due to the association of these factors with DD.
- Published
- 2023
8. Treatment patterns and survival in older adults with unresected nonmetastatic biliary tract cancers
- Author
-
Belkouz, Ali, de Savornin Lohman, Elise, Thumma, Jyothi R, Groot Koerkamp, Bas, de Reuver, Philip R, van Oijen, Martijn G H, Punt, Cornelis J A, Nathan, Hari, Klümpen, Heinz-Josef, Belkouz, Ali, de Savornin Lohman, Elise, Thumma, Jyothi R, Groot Koerkamp, Bas, de Reuver, Philip R, van Oijen, Martijn G H, Punt, Cornelis J A, Nathan, Hari, and Klümpen, Heinz-Josef
- Abstract
INTRODUCTION: The optimal treatment for unresected nonmetastatic biliary tract cancer (uBTC) is not well-established. The objective of this study was to analyze the treatment patterns and compare the differences in overall survival (OS) between different treatment strategies amongst older adults with uBTC.MATERIALS AND METHODS: We identified patients aged ≥65 years with uBTC using the Surveillance, Epidemiology, and End Results (SEER)-Medicare database (2004-2015). Treatments were classified into chemotherapy, chemoradiotherapy, and radiotherapy. The primary outcome was OS. The differences in OS were analyzed using Kaplan-Meier curves and multivariable Cox proportional hazard regression.RESULTS: A total of 4352 patients with uBTC were included. The median age was 80 years and median OS was 4.1 months. Most patients (67.3%, n = 2931) received no treatment, 19.1% chemotherapy (n = 833), 8.1% chemoradiotherapy (n = 354), and 5.4% radiotherapy alone (n = 234). Patients receiving no treatment were older and had more comorbidities. Chemotherapy was associated with significantly longer OS than no treatment in uBTC (hazard ratio [HR] 0.87, 95% confidence interval [CI] 0.79-0.95), but no difference was found in the subgroups of intrahepatic cholangiocarcinoma (iCCA; HR 0.87, 95% CI 0.75-1.00) and gallbladder carcinoma (GBC; HR 1.09, 95% CI 0.86-1.39). In the sensitivity analyses, capecitabine-based chemoradiotherapy showed significantly longer OS in uBTC compared to chemotherapy (adjusted HR 0.71, 95% CI 0.53-0.95).DISCUSSION: A minority of older patients with uBTC receive systemic treatments. Chemotherapy was associated with longer OS compared to no treatment in uBTC, but not in the subgroups of iCCA and GBC. The efficacy of chemoradiotherapy, especially in perihilar cholangiocarcinoma using capecitabine-based chemoradiotherapy, may be further evaluated in prospective clinical trials.
- Published
- 2023
9. The diagnostic value of staging laparoscopy in gallbladder cancer: a nationwide cohort study
- Author
-
Heelkunde assistenten niet opleiding, MS CGO, Stafbureau, Cancer, van Dooren, Mike, de Savornin Lohman, Elise A.J., Brekelmans, Eva, Vissers, Pauline A.J., Erdmann, Joris I., Braat, Andries E., Hagendoorn, Jeroen, Daams, Freek, van Dam, Ronald M., de Boer, Marieke T., van den Boezem, Peter B., Koerkamp, Bas Groot, de Reuver, Philip R., Heelkunde assistenten niet opleiding, MS CGO, Stafbureau, Cancer, van Dooren, Mike, de Savornin Lohman, Elise A.J., Brekelmans, Eva, Vissers, Pauline A.J., Erdmann, Joris I., Braat, Andries E., Hagendoorn, Jeroen, Daams, Freek, van Dam, Ronald M., de Boer, Marieke T., van den Boezem, Peter B., Koerkamp, Bas Groot, and de Reuver, Philip R.
- Published
- 2023
10. Adjuvant treatment for the elderly patient with resected gallbladder cancer:a SEER-Medicare analysis
- Author
-
de Savornin Lohman, Elise, Belkouz, Ali, Nuliyalu, Usha, Groot Koerkamp, Bas, Klümpen, Heinz-Josef, de Reuver, Philip, Nathan, Hari, de Savornin Lohman, Elise, Belkouz, Ali, Nuliyalu, Usha, Groot Koerkamp, Bas, Klümpen, Heinz-Josef, de Reuver, Philip, and Nathan, Hari
- Abstract
BACKGROUND: In patients with resected gallbladder cancer (GBC), the role of adjuvant chemotherapy (aCT) remains ill-defined, especially in elderly patients. This study evaluates the value of aCT in elderly patients with GBC and assesses response according to tumor stage.METHODS: Patients of ≥65 years of age with resected GBC diagnosed from 2004-2015 were identified using a Surveillance, Epidemiology and End Results (SEER)/Medicare linked database. After propensity score matching, survival of patients treated with aCT was compared to survival of patients who did not receive aCT using Kaplan-Meier and Cox proportional hazards analysis.RESULTS: Of 2,179 patients with resected GBC, 876 (25%) received aCT. In the full cohort of 810 propensity-score matched patients, survival did not differ between patients treated with aCT (17.6 months ) and without aCT (19.5 months, P=0.7720). Subgroup analysis showed that survival was significantly better after aCT in T3/T4 disease (12.3 vs. 7.2 months, P=0.013). Interaction analysis showed that benefit of aCT was primarily seen in combined T3/T4, node-positive disease (HR 0.612 , P=0.006). CONCLUSIONS: In this large cohort of elderly patients with resected GBC, aCT was not associated with increased survival. However, aCT may provide a survival benefit in T3/4, node-positive disease.
- Published
- 2022
11. Survival Outcomes After Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy in Patients with Synchronous Versus Metachronous Onset of Peritoneal Metastases of Colorectal Carcinoma
- Author
-
Dietz, Michelle V., van Kooten, Job P., Said, Ibrahim, Brandt-Kerkhof, Alexandra R.M., Verhoef, Cornelis, Bremers, Andreas J.A., de Wilt, Johannes H.W., de Reuver, Philip R., Madsen, Eva V.E., Dietz, Michelle V., van Kooten, Job P., Said, Ibrahim, Brandt-Kerkhof, Alexandra R.M., Verhoef, Cornelis, Bremers, Andreas J.A., de Wilt, Johannes H.W., de Reuver, Philip R., and Madsen, Eva V.E.
- Abstract
Background: Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment option for peritoneal metastases (PM) from colorectal carcinoma (CRC). Because of considerable morbidity, optimal patient selection is essential. This study was designed to determine the impact of the onset of PM (synchronous vs. metachronous) on survival outcomes after CRS-HIPEC. Methods: Patients undergoing CRS-HIPEC for colorectal PM in two academic centers in the Netherlands between 2010 and 2020 were eligible for inclusion. Patients were classified as synchronous (s-PM, i.e., diagnosis at time of presentation, staging, or primary surgery) or metachronous onset (m-PM, i.e., diagnosis during follow-up) of colorectal PM. Survival outcomes were compared between groups by Kaplan–Meier survival and Cox regression analyses. Results: Of 390 included patients, 179 (45.9%) had synchronous onset of colorectal PM. These patients more often presented with higher TN-stage and poor differentiation/signet cell histology. Treatment with perioperative chemotherapy was more common in s-PM patients. m-PM patients experienced more serious postoperative complications (Clavien-Dindo ≥ III). There was no significant difference in disease-free survival (DFS) between s-PM (median 9 months, interquartile range [IQR] 5–15) and m-PM patients (median 8 months, IQR 5–17). Overall survival (OS) was significantly shorter for s-PM (median 28 months, IQR 11–48) versus m-PM patients (median 33 months, IQR 18–66, p = 0.049). Synchronous onset of PM was not independently associated with OS in a multivariable analysis. Conclusions: Synchronous onset of colorectal PM was associated with poor tumor characteristics and more advanced disease, but was not an independent predictor of survival outcomes after CRS-HIPEC.
- Published
- 2022
12. 2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy
- Author
-
DeAngelis, Nicola, Catena, Fausto, Memeo, Riccardo, Coccolini, Federico, Martinez-Perez, Aleix, Romeo, Oreste M., De Simone, Belinda, Di Saverio, Salomone, Brustia, Raffaele, Rhaiem, Rami, Piardi, Tullio, Conticchio, Maria, Marchegiani, Francesco, Beghdadi, Nassiba, Abu-Zidan, Fikri M., Alikhanov, Ruslan, Allard, Marc-Antoine, Allievi, Niccolo, Amaddeo, Giuliana, Ansaloni, Luca, Andersson, Roland, Andolfi, Enrico, Azfar, Mohammad, Bala, Miklosh, Benkabbou, Amine, Ben-Ishay, Offir, Bianchi, Giorgio, Biffl, Walter L., Brunetti, Francesco, Carra, Maria Clotilde, Casanova, Daniel, Celentano, Valerio, Ceresoli, Marco, Chiara, Osvaldo, Cimbanassi, Stefania, Bini, Roberto, Coimbra, Raul, Luigi deAngelis, Gianm, Decembrino, Francesco, De Palma, Andrea, de Reuver, Philip R., Domingo, Carlos, Cotsoglou, Christian, Ferrero, Alessandro, Fraga, Gustavo P., Gaiani, Federica, Gheza, Federico, Gurrado, Angela, Harrison, Ewen, Henriquez, Angel, Hofmeyr, Stefan, Iadarola, Roberta, Kashuk, Jeffry L., Kianmanesh, Reza, Kirkpatrick, Andrew W., Kluger, Yoram, Landi, Filippo, Langella, Serena, Lapointe, Real, Le Roy, Bertrand, Luciani, Alain, Machado, Fernando, Maggi, Umberto, Maier, Ronald V., Mefire, Alain Chichom, Hiramatsu, Kazuhiro, Ordonez, Carlos, Patrizi, Franca, Planells, Manuel, Peitzman, Andrew B., Pekolj, Juan, Perdigao, Fabiano, Pereira, Bruno M., Pessaux, Patrick, Pisano, Michele, Puyana, Juan Carlos, Rizoli, Sandro, Portigliotti, Luca, Romito, Raffaele, Sakakushev, Boris, Sanei, Behnam, Scatton, Olivier, Serradilla-Martin, Mario, Schneck, Anne-Sophie, Sissoko, Mohammed Lamine, Sobhani, Iradj, ten Broek, Richard P., Testini, Mario, Valinas, Roberto, Veloudis, Giorgos, Vitali, Giulio Cesare, Weber, Dieter, Zorcolo, Luigi, Giuliante, Felice, Gavriilidis, Paschalis, Fuks, David, Sommacale, Daniele, DeAngelis, Nicola, Catena, Fausto, Memeo, Riccardo, Coccolini, Federico, Martinez-Perez, Aleix, Romeo, Oreste M., De Simone, Belinda, Di Saverio, Salomone, Brustia, Raffaele, Rhaiem, Rami, Piardi, Tullio, Conticchio, Maria, Marchegiani, Francesco, Beghdadi, Nassiba, Abu-Zidan, Fikri M., Alikhanov, Ruslan, Allard, Marc-Antoine, Allievi, Niccolo, Amaddeo, Giuliana, Ansaloni, Luca, Andersson, Roland, Andolfi, Enrico, Azfar, Mohammad, Bala, Miklosh, Benkabbou, Amine, Ben-Ishay, Offir, Bianchi, Giorgio, Biffl, Walter L., Brunetti, Francesco, Carra, Maria Clotilde, Casanova, Daniel, Celentano, Valerio, Ceresoli, Marco, Chiara, Osvaldo, Cimbanassi, Stefania, Bini, Roberto, Coimbra, Raul, Luigi deAngelis, Gianm, Decembrino, Francesco, De Palma, Andrea, de Reuver, Philip R., Domingo, Carlos, Cotsoglou, Christian, Ferrero, Alessandro, Fraga, Gustavo P., Gaiani, Federica, Gheza, Federico, Gurrado, Angela, Harrison, Ewen, Henriquez, Angel, Hofmeyr, Stefan, Iadarola, Roberta, Kashuk, Jeffry L., Kianmanesh, Reza, Kirkpatrick, Andrew W., Kluger, Yoram, Landi, Filippo, Langella, Serena, Lapointe, Real, Le Roy, Bertrand, Luciani, Alain, Machado, Fernando, Maggi, Umberto, Maier, Ronald V., Mefire, Alain Chichom, Hiramatsu, Kazuhiro, Ordonez, Carlos, Patrizi, Franca, Planells, Manuel, Peitzman, Andrew B., Pekolj, Juan, Perdigao, Fabiano, Pereira, Bruno M., Pessaux, Patrick, Pisano, Michele, Puyana, Juan Carlos, Rizoli, Sandro, Portigliotti, Luca, Romito, Raffaele, Sakakushev, Boris, Sanei, Behnam, Scatton, Olivier, Serradilla-Martin, Mario, Schneck, Anne-Sophie, Sissoko, Mohammed Lamine, Sobhani, Iradj, ten Broek, Richard P., Testini, Mario, Valinas, Roberto, Veloudis, Giorgos, Vitali, Giulio Cesare, Weber, Dieter, Zorcolo, Luigi, Giuliante, Felice, Gavriilidis, Paschalis, Fuks, David, and Sommacale, Daniele
- Abstract
Bile duct injury (BDI) is a dangerous complication of cholecystectomy, with significant postoperative sequelae for the patient in terms of morbidity, mortality, and long-term quality of life. BDIs have an estimated incidence of 0.4-1.5%, but considering the number of cholecystectomies performed worldwide, mostly by laparoscopy, surgeons must be prepared to manage this surgical challenge. Most BDIs are recognized either during the procedure or in the immediate postoperative period. However, some BDIs may be discovered later during the postoperative period, and this may translate to delayed or inappropriate treatments. Providing a specific diagnosis and a precise description of the BDI will expedite the decision-making process and increase the chance of treatment success. Subsequently, the choice and timing of the appropriate reconstructive strategy have a critical role in long-term prognosis. Currently, a wide spectrum of multidisciplinary interventions with different degrees of invasiveness is indicated for BDI management. These World Society of Emergency Surgery (WSES) guidelines have been produced following an exhaustive review of the current literature and an international expert panel discussion with the aim of providing evidence-based recommendations to facilitate and standardize the detection and management of BDIs during cholecystectomy. In particular, the 2020 WSES guidelines cover the following key aspects: (1) strategies to minimize the risk of BDI during cholecystectomy; (2) BDI rates in general surgery units and review of surgical practice; (3) how to classify, stage, and report BDI once detected; (4) how to manage an intraoperatively detected BDI; (5) indications for antibiotic treatment; (6) indications for clinical, biochemical, and imaging investigations for suspected BDI; and (7) how to manage a postoperatively detected BDI.
- Published
- 2021
- Full Text
- View/download PDF
13. 2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy
- Author
-
DeAngelis, Nicola, Catena, Fausto, Memeo, Riccardo, Coccolini, Federico, Martinez-Perez, Aleix, Romeo, Oreste M., De Simone, Belinda, Di Saverio, Salomone, Brustia, Raffaele, Rhaiem, Rami, Piardi, Tullio, Conticchio, Maria, Marchegiani, Francesco, Beghdadi, Nassiba, Abu-Zidan, Fikri M., Alikhanov, Ruslan, Allard, Marc-Antoine, Allievi, Niccolo, Amaddeo, Giuliana, Ansaloni, Luca, Andersson, Roland, Andolfi, Enrico, Azfar, Mohammad, Bala, Miklosh, Benkabbou, Amine, Ben-Ishay, Offir, Bianchi, Giorgio, Biffl, Walter L., Brunetti, Francesco, Carra, Maria Clotilde, Casanova, Daniel, Celentano, Valerio, Ceresoli, Marco, Chiara, Osvaldo, Cimbanassi, Stefania, Bini, Roberto, Coimbra, Raul, Luigi deAngelis, Gianm, Decembrino, Francesco, De Palma, Andrea, de Reuver, Philip R., Domingo, Carlos, Cotsoglou, Christian, Ferrero, Alessandro, Fraga, Gustavo P., Gaiani, Federica, Gheza, Federico, Gurrado, Angela, Harrison, Ewen, Henriquez, Angel, Hofmeyr, Stefan, Iadarola, Roberta, Kashuk, Jeffry L., Kianmanesh, Reza, Kirkpatrick, Andrew W., Kluger, Yoram, Landi, Filippo, Langella, Serena, Lapointe, Real, Le Roy, Bertrand, Luciani, Alain, Machado, Fernando, Maggi, Umberto, Maier, Ronald V., Mefire, Alain Chichom, Hiramatsu, Kazuhiro, Ordonez, Carlos, Patrizi, Franca, Planells, Manuel, Peitzman, Andrew B., Pekolj, Juan, Perdigao, Fabiano, Pereira, Bruno M., Pessaux, Patrick, Pisano, Michele, Puyana, Juan Carlos, Rizoli, Sandro, Portigliotti, Luca, Romito, Raffaele, Sakakushev, Boris, Sanei, Behnam, Scatton, Olivier, Serradilla-Martin, Mario, Schneck, Anne-Sophie, Sissoko, Mohammed Lamine, Sobhani, Iradj, ten Broek, Richard P., Testini, Mario, Valinas, Roberto, Veloudis, Giorgos, Vitali, Giulio Cesare, Weber, Dieter, Zorcolo, Luigi, Giuliante, Felice, Gavriilidis, Paschalis, Fuks, David, Sommacale, Daniele, DeAngelis, Nicola, Catena, Fausto, Memeo, Riccardo, Coccolini, Federico, Martinez-Perez, Aleix, Romeo, Oreste M., De Simone, Belinda, Di Saverio, Salomone, Brustia, Raffaele, Rhaiem, Rami, Piardi, Tullio, Conticchio, Maria, Marchegiani, Francesco, Beghdadi, Nassiba, Abu-Zidan, Fikri M., Alikhanov, Ruslan, Allard, Marc-Antoine, Allievi, Niccolo, Amaddeo, Giuliana, Ansaloni, Luca, Andersson, Roland, Andolfi, Enrico, Azfar, Mohammad, Bala, Miklosh, Benkabbou, Amine, Ben-Ishay, Offir, Bianchi, Giorgio, Biffl, Walter L., Brunetti, Francesco, Carra, Maria Clotilde, Casanova, Daniel, Celentano, Valerio, Ceresoli, Marco, Chiara, Osvaldo, Cimbanassi, Stefania, Bini, Roberto, Coimbra, Raul, Luigi deAngelis, Gianm, Decembrino, Francesco, De Palma, Andrea, de Reuver, Philip R., Domingo, Carlos, Cotsoglou, Christian, Ferrero, Alessandro, Fraga, Gustavo P., Gaiani, Federica, Gheza, Federico, Gurrado, Angela, Harrison, Ewen, Henriquez, Angel, Hofmeyr, Stefan, Iadarola, Roberta, Kashuk, Jeffry L., Kianmanesh, Reza, Kirkpatrick, Andrew W., Kluger, Yoram, Landi, Filippo, Langella, Serena, Lapointe, Real, Le Roy, Bertrand, Luciani, Alain, Machado, Fernando, Maggi, Umberto, Maier, Ronald V., Mefire, Alain Chichom, Hiramatsu, Kazuhiro, Ordonez, Carlos, Patrizi, Franca, Planells, Manuel, Peitzman, Andrew B., Pekolj, Juan, Perdigao, Fabiano, Pereira, Bruno M., Pessaux, Patrick, Pisano, Michele, Puyana, Juan Carlos, Rizoli, Sandro, Portigliotti, Luca, Romito, Raffaele, Sakakushev, Boris, Sanei, Behnam, Scatton, Olivier, Serradilla-Martin, Mario, Schneck, Anne-Sophie, Sissoko, Mohammed Lamine, Sobhani, Iradj, ten Broek, Richard P., Testini, Mario, Valinas, Roberto, Veloudis, Giorgos, Vitali, Giulio Cesare, Weber, Dieter, Zorcolo, Luigi, Giuliante, Felice, Gavriilidis, Paschalis, Fuks, David, and Sommacale, Daniele
- Abstract
Bile duct injury (BDI) is a dangerous complication of cholecystectomy, with significant postoperative sequelae for the patient in terms of morbidity, mortality, and long-term quality of life. BDIs have an estimated incidence of 0.4-1.5%, but considering the number of cholecystectomies performed worldwide, mostly by laparoscopy, surgeons must be prepared to manage this surgical challenge. Most BDIs are recognized either during the procedure or in the immediate postoperative period. However, some BDIs may be discovered later during the postoperative period, and this may translate to delayed or inappropriate treatments. Providing a specific diagnosis and a precise description of the BDI will expedite the decision-making process and increase the chance of treatment success. Subsequently, the choice and timing of the appropriate reconstructive strategy have a critical role in long-term prognosis. Currently, a wide spectrum of multidisciplinary interventions with different degrees of invasiveness is indicated for BDI management. These World Society of Emergency Surgery (WSES) guidelines have been produced following an exhaustive review of the current literature and an international expert panel discussion with the aim of providing evidence-based recommendations to facilitate and standardize the detection and management of BDIs during cholecystectomy. In particular, the 2020 WSES guidelines cover the following key aspects: (1) strategies to minimize the risk of BDI during cholecystectomy; (2) BDI rates in general surgery units and review of surgical practice; (3) how to classify, stage, and report BDI once detected; (4) how to manage an intraoperatively detected BDI; (5) indications for antibiotic treatment; (6) indications for clinical, biochemical, and imaging investigations for suspected BDI; and (7) how to manage a postoperatively detected BDI.
- Published
- 2021
- Full Text
- View/download PDF
14. Perioperative SARS-CoV-2 infections increase mortality, pulmonary complications, and thromboembolic events:A Dutch, multicenter, matched-cohort clinical study
- Author
-
Jonker, Pascal K.C., van der Plas, Willemijn Y., Steinkamp, Pieter J., Poelstra, Ralph, Emous, Marloes, van der Meij, Wout, Thunnissen, Floris, Bierman, Wouter F.W., Struys, Michel M.R.F., de Reuver, Philip R., de Vries, Jean Paul P.M., Kruijff, Schelto, van Ginhoven, Tessa, Jonker, Pascal K.C., van der Plas, Willemijn Y., Steinkamp, Pieter J., Poelstra, Ralph, Emous, Marloes, van der Meij, Wout, Thunnissen, Floris, Bierman, Wouter F.W., Struys, Michel M.R.F., de Reuver, Philip R., de Vries, Jean Paul P.M., Kruijff, Schelto, and van Ginhoven, Tessa
- Abstract
Background: A direct comparison of severe acute respiratory syndrome coronavirus 2 positive patients with a severe acute respiratory syndrome coronavirus 2 negative control group undergoing an operative intervention during the current pandemic is lacking, and a reliable estimate of the assumed difference in morbidity and mortality between both patient categories remains unknown. Methods: We included all consecutive patients with a confirmed pre- or postoperative severe acute respiratory syndrome coronavirus 2 positive status (operated in 27 hospitals) and negative control patients (operated in 4 hospitals) undergoing emergency or elective operations. A propensity score-matched comparison of clinical outcomes was performed between severe acute respiratory syndrome coronavirus 2 positive and negative tested patients (control group). Primary outcome was overall 30-day mortality rate between both groups. Main secondary outcomes were overall, pulmonary, and thromboembolic complications. Results: In total, 161 severe acute respiratory syndrome coronavirus 2 positive and 342 control severe acute respiratory syndrome coronavirus 2 negative patients were included in this study. The 30-day overall postoperative mortality rate was greater in the severe acute respiratory syndrome coronavirus 2 positive cohort compared with the negative control group (16% vs 4% respectively; P = .007). After propensity score matching, the severe acute respiratory syndrome coronavirus 2 positive group consisted of 123 patients (median 70 years of age [interquartile range 59–77] and 55% male) were compared with 196 patients in the matched control group (median 69 years (interquartile range 58–75] and 53% male). The 30-day mortality rate and risk were greater in the severe acute respiratory syndrome coronavirus 2 positive group compared with the matched control group (12% vs 4%; P = .009 and odds ratio 3.4 [95% confidence interval 1.5–8.5]; P = .005, respectively). Overall, pulmonary and thrombo
- Published
- 2021
15. 2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy
- Author
-
DeAngelis, Nicola, Catena, Fausto, Memeo, Riccardo, Coccolini, Federico, Martinez-Perez, Aleix, Romeo, Oreste M., De Simone, Belinda, Di Saverio, Salomone, Brustia, Raffaele, Rhaiem, Rami, Piardi, Tullio, Conticchio, Maria, Marchegiani, Francesco, Beghdadi, Nassiba, Abu-Zidan, Fikri M., Alikhanov, Ruslan, Allard, Marc-Antoine, Allievi, Niccolo, Amaddeo, Giuliana, Ansaloni, Luca, Andersson, Roland, Andolfi, Enrico, Azfar, Mohammad, Bala, Miklosh, Benkabbou, Amine, Ben-Ishay, Offir, Bianchi, Giorgio, Biffl, Walter L., Brunetti, Francesco, Carra, Maria Clotilde, Casanova, Daniel, Celentano, Valerio, Ceresoli, Marco, Chiara, Osvaldo, Cimbanassi, Stefania, Bini, Roberto, Coimbra, Raul, Luigi deAngelis, Gianm, Decembrino, Francesco, De Palma, Andrea, de Reuver, Philip R., Domingo, Carlos, Cotsoglou, Christian, Ferrero, Alessandro, Fraga, Gustavo P., Gaiani, Federica, Gheza, Federico, Gurrado, Angela, Harrison, Ewen, Henriquez, Angel, Hofmeyr, Stefan, Iadarola, Roberta, Kashuk, Jeffry L., Kianmanesh, Reza, Kirkpatrick, Andrew W., Kluger, Yoram, Landi, Filippo, Langella, Serena, Lapointe, Real, Le Roy, Bertrand, Luciani, Alain, Machado, Fernando, Maggi, Umberto, Maier, Ronald V., Mefire, Alain Chichom, Hiramatsu, Kazuhiro, Ordonez, Carlos, Patrizi, Franca, Planells, Manuel, Peitzman, Andrew B., Pekolj, Juan, Perdigao, Fabiano, Pereira, Bruno M., Pessaux, Patrick, Pisano, Michele, Puyana, Juan Carlos, Rizoli, Sandro, Portigliotti, Luca, Romito, Raffaele, Sakakushev, Boris, Sanei, Behnam, Scatton, Olivier, Serradilla-Martin, Mario, Schneck, Anne-Sophie, Sissoko, Mohammed Lamine, Sobhani, Iradj, ten Broek, Richard P., Testini, Mario, Valinas, Roberto, Veloudis, Giorgos, Vitali, Giulio Cesare, Weber, Dieter, Zorcolo, Luigi, Giuliante, Felice, Gavriilidis, Paschalis, Fuks, David, Sommacale, Daniele, DeAngelis, Nicola, Catena, Fausto, Memeo, Riccardo, Coccolini, Federico, Martinez-Perez, Aleix, Romeo, Oreste M., De Simone, Belinda, Di Saverio, Salomone, Brustia, Raffaele, Rhaiem, Rami, Piardi, Tullio, Conticchio, Maria, Marchegiani, Francesco, Beghdadi, Nassiba, Abu-Zidan, Fikri M., Alikhanov, Ruslan, Allard, Marc-Antoine, Allievi, Niccolo, Amaddeo, Giuliana, Ansaloni, Luca, Andersson, Roland, Andolfi, Enrico, Azfar, Mohammad, Bala, Miklosh, Benkabbou, Amine, Ben-Ishay, Offir, Bianchi, Giorgio, Biffl, Walter L., Brunetti, Francesco, Carra, Maria Clotilde, Casanova, Daniel, Celentano, Valerio, Ceresoli, Marco, Chiara, Osvaldo, Cimbanassi, Stefania, Bini, Roberto, Coimbra, Raul, Luigi deAngelis, Gianm, Decembrino, Francesco, De Palma, Andrea, de Reuver, Philip R., Domingo, Carlos, Cotsoglou, Christian, Ferrero, Alessandro, Fraga, Gustavo P., Gaiani, Federica, Gheza, Federico, Gurrado, Angela, Harrison, Ewen, Henriquez, Angel, Hofmeyr, Stefan, Iadarola, Roberta, Kashuk, Jeffry L., Kianmanesh, Reza, Kirkpatrick, Andrew W., Kluger, Yoram, Landi, Filippo, Langella, Serena, Lapointe, Real, Le Roy, Bertrand, Luciani, Alain, Machado, Fernando, Maggi, Umberto, Maier, Ronald V., Mefire, Alain Chichom, Hiramatsu, Kazuhiro, Ordonez, Carlos, Patrizi, Franca, Planells, Manuel, Peitzman, Andrew B., Pekolj, Juan, Perdigao, Fabiano, Pereira, Bruno M., Pessaux, Patrick, Pisano, Michele, Puyana, Juan Carlos, Rizoli, Sandro, Portigliotti, Luca, Romito, Raffaele, Sakakushev, Boris, Sanei, Behnam, Scatton, Olivier, Serradilla-Martin, Mario, Schneck, Anne-Sophie, Sissoko, Mohammed Lamine, Sobhani, Iradj, ten Broek, Richard P., Testini, Mario, Valinas, Roberto, Veloudis, Giorgos, Vitali, Giulio Cesare, Weber, Dieter, Zorcolo, Luigi, Giuliante, Felice, Gavriilidis, Paschalis, Fuks, David, and Sommacale, Daniele
- Abstract
Bile duct injury (BDI) is a dangerous complication of cholecystectomy, with significant postoperative sequelae for the patient in terms of morbidity, mortality, and long-term quality of life. BDIs have an estimated incidence of 0.4-1.5%, but considering the number of cholecystectomies performed worldwide, mostly by laparoscopy, surgeons must be prepared to manage this surgical challenge. Most BDIs are recognized either during the procedure or in the immediate postoperative period. However, some BDIs may be discovered later during the postoperative period, and this may translate to delayed or inappropriate treatments. Providing a specific diagnosis and a precise description of the BDI will expedite the decision-making process and increase the chance of treatment success. Subsequently, the choice and timing of the appropriate reconstructive strategy have a critical role in long-term prognosis. Currently, a wide spectrum of multidisciplinary interventions with different degrees of invasiveness is indicated for BDI management. These World Society of Emergency Surgery (WSES) guidelines have been produced following an exhaustive review of the current literature and an international expert panel discussion with the aim of providing evidence-based recommendations to facilitate and standardize the detection and management of BDIs during cholecystectomy. In particular, the 2020 WSES guidelines cover the following key aspects: (1) strategies to minimize the risk of BDI during cholecystectomy; (2) BDI rates in general surgery units and review of surgical practice; (3) how to classify, stage, and report BDI once detected; (4) how to manage an intraoperatively detected BDI; (5) indications for antibiotic treatment; (6) indications for clinical, biochemical, and imaging investigations for suspected BDI; and (7) how to manage a postoperatively detected BDI.
- Published
- 2021
- Full Text
- View/download PDF
16. 2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy
- Author
-
DeAngelis, Nicola, Catena, Fausto, Memeo, Riccardo, Coccolini, Federico, Martinez-Perez, Aleix, Romeo, Oreste M., De Simone, Belinda, Di Saverio, Salomone, Brustia, Raffaele, Rhaiem, Rami, Piardi, Tullio, Conticchio, Maria, Marchegiani, Francesco, Beghdadi, Nassiba, Abu-Zidan, Fikri M., Alikhanov, Ruslan, Allard, Marc-Antoine, Allievi, Niccolo, Amaddeo, Giuliana, Ansaloni, Luca, Andersson, Roland, Andolfi, Enrico, Azfar, Mohammad, Bala, Miklosh, Benkabbou, Amine, Ben-Ishay, Offir, Bianchi, Giorgio, Biffl, Walter L., Brunetti, Francesco, Carra, Maria Clotilde, Casanova, Daniel, Celentano, Valerio, Ceresoli, Marco, Chiara, Osvaldo, Cimbanassi, Stefania, Bini, Roberto, Coimbra, Raul, Luigi deAngelis, Gianm, Decembrino, Francesco, De Palma, Andrea, de Reuver, Philip R., Domingo, Carlos, Cotsoglou, Christian, Ferrero, Alessandro, Fraga, Gustavo P., Gaiani, Federica, Gheza, Federico, Gurrado, Angela, Harrison, Ewen, Henriquez, Angel, Hofmeyr, Stefan, Iadarola, Roberta, Kashuk, Jeffry L., Kianmanesh, Reza, Kirkpatrick, Andrew W., Kluger, Yoram, Landi, Filippo, Langella, Serena, Lapointe, Real, Le Roy, Bertrand, Luciani, Alain, Machado, Fernando, Maggi, Umberto, Maier, Ronald V., Mefire, Alain Chichom, Hiramatsu, Kazuhiro, Ordonez, Carlos, Patrizi, Franca, Planells, Manuel, Peitzman, Andrew B., Pekolj, Juan, Perdigao, Fabiano, Pereira, Bruno M., Pessaux, Patrick, Pisano, Michele, Puyana, Juan Carlos, Rizoli, Sandro, Portigliotti, Luca, Romito, Raffaele, Sakakushev, Boris, Sanei, Behnam, Scatton, Olivier, Serradilla-Martin, Mario, Schneck, Anne-Sophie, Sissoko, Mohammed Lamine, Sobhani, Iradj, ten Broek, Richard P., Testini, Mario, Valinas, Roberto, Veloudis, Giorgos, Vitali, Giulio Cesare, Weber, Dieter, Zorcolo, Luigi, Giuliante, Felice, Gavriilidis, Paschalis, Fuks, David, Sommacale, Daniele, DeAngelis, Nicola, Catena, Fausto, Memeo, Riccardo, Coccolini, Federico, Martinez-Perez, Aleix, Romeo, Oreste M., De Simone, Belinda, Di Saverio, Salomone, Brustia, Raffaele, Rhaiem, Rami, Piardi, Tullio, Conticchio, Maria, Marchegiani, Francesco, Beghdadi, Nassiba, Abu-Zidan, Fikri M., Alikhanov, Ruslan, Allard, Marc-Antoine, Allievi, Niccolo, Amaddeo, Giuliana, Ansaloni, Luca, Andersson, Roland, Andolfi, Enrico, Azfar, Mohammad, Bala, Miklosh, Benkabbou, Amine, Ben-Ishay, Offir, Bianchi, Giorgio, Biffl, Walter L., Brunetti, Francesco, Carra, Maria Clotilde, Casanova, Daniel, Celentano, Valerio, Ceresoli, Marco, Chiara, Osvaldo, Cimbanassi, Stefania, Bini, Roberto, Coimbra, Raul, Luigi deAngelis, Gianm, Decembrino, Francesco, De Palma, Andrea, de Reuver, Philip R., Domingo, Carlos, Cotsoglou, Christian, Ferrero, Alessandro, Fraga, Gustavo P., Gaiani, Federica, Gheza, Federico, Gurrado, Angela, Harrison, Ewen, Henriquez, Angel, Hofmeyr, Stefan, Iadarola, Roberta, Kashuk, Jeffry L., Kianmanesh, Reza, Kirkpatrick, Andrew W., Kluger, Yoram, Landi, Filippo, Langella, Serena, Lapointe, Real, Le Roy, Bertrand, Luciani, Alain, Machado, Fernando, Maggi, Umberto, Maier, Ronald V., Mefire, Alain Chichom, Hiramatsu, Kazuhiro, Ordonez, Carlos, Patrizi, Franca, Planells, Manuel, Peitzman, Andrew B., Pekolj, Juan, Perdigao, Fabiano, Pereira, Bruno M., Pessaux, Patrick, Pisano, Michele, Puyana, Juan Carlos, Rizoli, Sandro, Portigliotti, Luca, Romito, Raffaele, Sakakushev, Boris, Sanei, Behnam, Scatton, Olivier, Serradilla-Martin, Mario, Schneck, Anne-Sophie, Sissoko, Mohammed Lamine, Sobhani, Iradj, ten Broek, Richard P., Testini, Mario, Valinas, Roberto, Veloudis, Giorgos, Vitali, Giulio Cesare, Weber, Dieter, Zorcolo, Luigi, Giuliante, Felice, Gavriilidis, Paschalis, Fuks, David, and Sommacale, Daniele
- Abstract
Bile duct injury (BDI) is a dangerous complication of cholecystectomy, with significant postoperative sequelae for the patient in terms of morbidity, mortality, and long-term quality of life. BDIs have an estimated incidence of 0.4-1.5%, but considering the number of cholecystectomies performed worldwide, mostly by laparoscopy, surgeons must be prepared to manage this surgical challenge. Most BDIs are recognized either during the procedure or in the immediate postoperative period. However, some BDIs may be discovered later during the postoperative period, and this may translate to delayed or inappropriate treatments. Providing a specific diagnosis and a precise description of the BDI will expedite the decision-making process and increase the chance of treatment success. Subsequently, the choice and timing of the appropriate reconstructive strategy have a critical role in long-term prognosis. Currently, a wide spectrum of multidisciplinary interventions with different degrees of invasiveness is indicated for BDI management. These World Society of Emergency Surgery (WSES) guidelines have been produced following an exhaustive review of the current literature and an international expert panel discussion with the aim of providing evidence-based recommendations to facilitate and standardize the detection and management of BDIs during cholecystectomy. In particular, the 2020 WSES guidelines cover the following key aspects: (1) strategies to minimize the risk of BDI during cholecystectomy; (2) BDI rates in general surgery units and review of surgical practice; (3) how to classify, stage, and report BDI once detected; (4) how to manage an intraoperatively detected BDI; (5) indications for antibiotic treatment; (6) indications for clinical, biochemical, and imaging investigations for suspected BDI; and (7) how to manage a postoperatively detected BDI.
- Published
- 2021
- Full Text
- View/download PDF
17. 2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy
- Author
-
DeAngelis, Nicola, Catena, Fausto, Memeo, Riccardo, Coccolini, Federico, Martinez-Perez, Aleix, Romeo, Oreste M., De Simone, Belinda, Di Saverio, Salomone, Brustia, Raffaele, Rhaiem, Rami, Piardi, Tullio, Conticchio, Maria, Marchegiani, Francesco, Beghdadi, Nassiba, Abu-Zidan, Fikri M., Alikhanov, Ruslan, Allard, Marc-Antoine, Allievi, Niccolo, Amaddeo, Giuliana, Ansaloni, Luca, Andersson, Roland, Andolfi, Enrico, Azfar, Mohammad, Bala, Miklosh, Benkabbou, Amine, Ben-Ishay, Offir, Bianchi, Giorgio, Biffl, Walter L., Brunetti, Francesco, Carra, Maria Clotilde, Casanova, Daniel, Celentano, Valerio, Ceresoli, Marco, Chiara, Osvaldo, Cimbanassi, Stefania, Bini, Roberto, Coimbra, Raul, Luigi deAngelis, Gianm, Decembrino, Francesco, De Palma, Andrea, de Reuver, Philip R., Domingo, Carlos, Cotsoglou, Christian, Ferrero, Alessandro, Fraga, Gustavo P., Gaiani, Federica, Gheza, Federico, Gurrado, Angela, Harrison, Ewen, Henriquez, Angel, Hofmeyr, Stefan, Iadarola, Roberta, Kashuk, Jeffry L., Kianmanesh, Reza, Kirkpatrick, Andrew W., Kluger, Yoram, Landi, Filippo, Langella, Serena, Lapointe, Real, Le Roy, Bertrand, Luciani, Alain, Machado, Fernando, Maggi, Umberto, Maier, Ronald V., Mefire, Alain Chichom, Hiramatsu, Kazuhiro, Ordonez, Carlos, Patrizi, Franca, Planells, Manuel, Peitzman, Andrew B., Pekolj, Juan, Perdigao, Fabiano, Pereira, Bruno M., Pessaux, Patrick, Pisano, Michele, Puyana, Juan Carlos, Rizoli, Sandro, Portigliotti, Luca, Romito, Raffaele, Sakakushev, Boris, Sanei, Behnam, Scatton, Olivier, Serradilla-Martin, Mario, Schneck, Anne-Sophie, Sissoko, Mohammed Lamine, Sobhani, Iradj, ten Broek, Richard P., Testini, Mario, Valinas, Roberto, Veloudis, Giorgos, Vitali, Giulio Cesare, Weber, Dieter, Zorcolo, Luigi, Giuliante, Felice, Gavriilidis, Paschalis, Fuks, David, Sommacale, Daniele, DeAngelis, Nicola, Catena, Fausto, Memeo, Riccardo, Coccolini, Federico, Martinez-Perez, Aleix, Romeo, Oreste M., De Simone, Belinda, Di Saverio, Salomone, Brustia, Raffaele, Rhaiem, Rami, Piardi, Tullio, Conticchio, Maria, Marchegiani, Francesco, Beghdadi, Nassiba, Abu-Zidan, Fikri M., Alikhanov, Ruslan, Allard, Marc-Antoine, Allievi, Niccolo, Amaddeo, Giuliana, Ansaloni, Luca, Andersson, Roland, Andolfi, Enrico, Azfar, Mohammad, Bala, Miklosh, Benkabbou, Amine, Ben-Ishay, Offir, Bianchi, Giorgio, Biffl, Walter L., Brunetti, Francesco, Carra, Maria Clotilde, Casanova, Daniel, Celentano, Valerio, Ceresoli, Marco, Chiara, Osvaldo, Cimbanassi, Stefania, Bini, Roberto, Coimbra, Raul, Luigi deAngelis, Gianm, Decembrino, Francesco, De Palma, Andrea, de Reuver, Philip R., Domingo, Carlos, Cotsoglou, Christian, Ferrero, Alessandro, Fraga, Gustavo P., Gaiani, Federica, Gheza, Federico, Gurrado, Angela, Harrison, Ewen, Henriquez, Angel, Hofmeyr, Stefan, Iadarola, Roberta, Kashuk, Jeffry L., Kianmanesh, Reza, Kirkpatrick, Andrew W., Kluger, Yoram, Landi, Filippo, Langella, Serena, Lapointe, Real, Le Roy, Bertrand, Luciani, Alain, Machado, Fernando, Maggi, Umberto, Maier, Ronald V., Mefire, Alain Chichom, Hiramatsu, Kazuhiro, Ordonez, Carlos, Patrizi, Franca, Planells, Manuel, Peitzman, Andrew B., Pekolj, Juan, Perdigao, Fabiano, Pereira, Bruno M., Pessaux, Patrick, Pisano, Michele, Puyana, Juan Carlos, Rizoli, Sandro, Portigliotti, Luca, Romito, Raffaele, Sakakushev, Boris, Sanei, Behnam, Scatton, Olivier, Serradilla-Martin, Mario, Schneck, Anne-Sophie, Sissoko, Mohammed Lamine, Sobhani, Iradj, ten Broek, Richard P., Testini, Mario, Valinas, Roberto, Veloudis, Giorgos, Vitali, Giulio Cesare, Weber, Dieter, Zorcolo, Luigi, Giuliante, Felice, Gavriilidis, Paschalis, Fuks, David, and Sommacale, Daniele
- Abstract
Bile duct injury (BDI) is a dangerous complication of cholecystectomy, with significant postoperative sequelae for the patient in terms of morbidity, mortality, and long-term quality of life. BDIs have an estimated incidence of 0.4-1.5%, but considering the number of cholecystectomies performed worldwide, mostly by laparoscopy, surgeons must be prepared to manage this surgical challenge. Most BDIs are recognized either during the procedure or in the immediate postoperative period. However, some BDIs may be discovered later during the postoperative period, and this may translate to delayed or inappropriate treatments. Providing a specific diagnosis and a precise description of the BDI will expedite the decision-making process and increase the chance of treatment success. Subsequently, the choice and timing of the appropriate reconstructive strategy have a critical role in long-term prognosis. Currently, a wide spectrum of multidisciplinary interventions with different degrees of invasiveness is indicated for BDI management. These World Society of Emergency Surgery (WSES) guidelines have been produced following an exhaustive review of the current literature and an international expert panel discussion with the aim of providing evidence-based recommendations to facilitate and standardize the detection and management of BDIs during cholecystectomy. In particular, the 2020 WSES guidelines cover the following key aspects: (1) strategies to minimize the risk of BDI during cholecystectomy; (2) BDI rates in general surgery units and review of surgical practice; (3) how to classify, stage, and report BDI once detected; (4) how to manage an intraoperatively detected BDI; (5) indications for antibiotic treatment; (6) indications for clinical, biochemical, and imaging investigations for suspected BDI; and (7) how to manage a postoperatively detected BDI.
- Published
- 2021
- Full Text
- View/download PDF
18. Perioperative Systemic Therapy vs Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Alone for Resectable Colorectal Peritoneal Metastases: A Phase 2 Randomized Clinical Trial
- Author
-
Arts Assistenten CTC, MS CGO, Cancer, MS Medische Oncologie, Cancer Center Patiëntenzorg, Lab Translational Oncology, Regenerative Medicine and Stem Cells, Rovers, Koen P., Bakkers, Checca, Nienhuijs, Simon W., Burger, Jacobus W.A., Creemers, Geert Jan M., Thijs, Anna M.J., Brandt-Kerkhof, Alexandra R.M., Madsen, Eva V.E., Van Meerten, Esther, Tuynman, Jurriaan B., Kusters, Miranda, Versteeg, Kathelijn S., Aalbers, Arend G.J., Kok, Niels F.M., Buffart, Tineke E., Wiezer, Marinus J., Boerma, Djamila, Los, Maartje, De Reuver, Philip R., Bremers, Andreas J.A., Verheul, Henk M.W., Kruijff, Schelto, De Groot, Derk Jan A., Witkamp, Arjen J., Van Grevenstein, Wilhelmina M.U., Koopman, Miriam, Nederend, Joost, Lahaye, Max J., Kranenburg, Onno, Fijneman, Remond J.A., Van 'T Erve, Iris, Snaebjornsson, Petur, Hemmer, Patrick H.J., Dijkgraaf, Marcel G.W., Punt, Cornelis J.A., Tanis, Pieter J., De Hingh, Ignace H.J.T., Arts Assistenten CTC, MS CGO, Cancer, MS Medische Oncologie, Cancer Center Patiëntenzorg, Lab Translational Oncology, Regenerative Medicine and Stem Cells, Rovers, Koen P., Bakkers, Checca, Nienhuijs, Simon W., Burger, Jacobus W.A., Creemers, Geert Jan M., Thijs, Anna M.J., Brandt-Kerkhof, Alexandra R.M., Madsen, Eva V.E., Van Meerten, Esther, Tuynman, Jurriaan B., Kusters, Miranda, Versteeg, Kathelijn S., Aalbers, Arend G.J., Kok, Niels F.M., Buffart, Tineke E., Wiezer, Marinus J., Boerma, Djamila, Los, Maartje, De Reuver, Philip R., Bremers, Andreas J.A., Verheul, Henk M.W., Kruijff, Schelto, De Groot, Derk Jan A., Witkamp, Arjen J., Van Grevenstein, Wilhelmina M.U., Koopman, Miriam, Nederend, Joost, Lahaye, Max J., Kranenburg, Onno, Fijneman, Remond J.A., Van 'T Erve, Iris, Snaebjornsson, Petur, Hemmer, Patrick H.J., Dijkgraaf, Marcel G.W., Punt, Cornelis J.A., Tanis, Pieter J., and De Hingh, Ignace H.J.T.
- Published
- 2021
19. Severe Salmonella spp. or Campylobacter spp. Infection and the Risk of Biliary Tract Cancer: A Population-Based Study
- Author
-
de Savornin Lohman, Elise, Duijster, Janneke, Groot Koerkamp, Bas, van der Post, Rachel, Franz, Eelco, Mughini Gras, Lapo, de Reuver, Philip, de Savornin Lohman, Elise, Duijster, Janneke, Groot Koerkamp, Bas, van der Post, Rachel, Franz, Eelco, Mughini Gras, Lapo, and de Reuver, Philip
- Abstract
Salmonella spp. infection has shown to have oncogenic transformative effects and thereby increases the risk of certain cancers. For Campylobacter spp., similar effects have been demonstrated. Risk factor identification may allow for timely diagnosis and preventive treatment. To substantiate the oncogenic potential of Salmonella and Campylobacter spp., this study compared the incidence of extrahepatic biliary tract cancer (BTC) in patients with diagnosed Salmonella or Campylobacter spp. infection with BTC incidence in the Netherlands. National infectious diseases surveillance records of patients diagnosed with a laboratory-confirmed Salmonella or Campylobacter spp. infection during 1999-2016 were linked to the Netherlands Cancer Registry. Incidence of BTC in Salmonella and Campylobacter spp. patients was compared to the incidence of BTC in the general population using Standardized Incidence Ratios (SIRs). In total, 16,252 patients were diagnosed with Salmonella spp. and 27,668 with Campylobacter spp. infection. Nine patients developed BTC at a median of 46 months (13-67) after Salmonella spp. infection and seven at a median of 60 months (18-138) after Campylobacter spp. infection. SIR of BTC in salmonellosis patients was 1.53 (95% CI 0.70-2.91). In patients aged <60 years, the SIR was 1.74 (95% CI 0.36-5.04). For campylobacteriosis patients, the SIR was 0.97 (95% CI 0.39-2.00). Even though Salmonella or Campylobacter spp. infection was not significantly associated with increased BTC risk in this cohort, it remains extremely important to study potential risk factors for cancer to facilitate screening and ultimately improve prognosis of cancer patients.
- Published
- 2020
20. Trends in Treatment and Survival of Gallbladder Cancer in the Netherlands; Identifying Gaps and Opportunities from a Nation-Wide Cohort
- Author
-
de Savornin Lohman, Elise, de Bitter, Tessa, Verhoeven, Rob, van der Geest, Lydia, Hagendoorn, Jeroen, Mohammad, Nadia Haj, Daams, Freek, Heinz-Josef Klümpen, Klümpen, van Gulik, Thomas, Erdmann, Joris, de Boer, Marieke, Hoogwater, Frederik, Koerkamp, Bas Groot, Braat, Andries, Verheij, Joanne, Nagtegaal, Iris, van Laarhoven, Cornelis, van den Boezem, Peter, van der Post, Rachel, de Reuver, Philip, de Savornin Lohman, Elise, de Bitter, Tessa, Verhoeven, Rob, van der Geest, Lydia, Hagendoorn, Jeroen, Mohammad, Nadia Haj, Daams, Freek, Heinz-Josef Klümpen, Klümpen, van Gulik, Thomas, Erdmann, Joris, de Boer, Marieke, Hoogwater, Frederik, Koerkamp, Bas Groot, Braat, Andries, Verheij, Joanne, Nagtegaal, Iris, van Laarhoven, Cornelis, van den Boezem, Peter, van der Post, Rachel, and de Reuver, Philip
- Published
- 2020
21. Severe Salmonella spp. or Campylobacter spp. Infection and the Risk of Biliary Tract Cancer: A Population-Based Study
- Author
-
IRAS OH Epidemiology Microbial Agents, dIRAS RA-I&I I&I, de Savornin Lohman, Elise, Duijster, Janneke, Groot Koerkamp, Bas, van der Post, Rachel, Franz, Eelco, Mughini Gras, Lapo, de Reuver, Philip, IRAS OH Epidemiology Microbial Agents, dIRAS RA-I&I I&I, de Savornin Lohman, Elise, Duijster, Janneke, Groot Koerkamp, Bas, van der Post, Rachel, Franz, Eelco, Mughini Gras, Lapo, and de Reuver, Philip
- Published
- 2020
22. Trends in Treatment and Survival of Gallbladder Cancer in the Netherlands; Identifying Gaps and Opportunities from a Nation-Wide Cohort
- Author
-
de Savornin Lohman, Elise, de Bitter, Tessa, Verhoeven, Rob, van der Geest, Lydia, Hagendoorn, Jeroen, Mohammad, Nadia Haj, Daams, Freek, Heinz-Josef Klümpen, Klümpen, van Gulik, Thomas, Erdmann, Joris, de Boer, Marieke, Hoogwater, Frederik, Koerkamp, Bas Groot, Braat, Andries, Verheij, Joanne, Nagtegaal, Iris, van Laarhoven, Cornelis, van den Boezem, Peter, van der Post, Rachel, de Reuver, Philip, de Savornin Lohman, Elise, de Bitter, Tessa, Verhoeven, Rob, van der Geest, Lydia, Hagendoorn, Jeroen, Mohammad, Nadia Haj, Daams, Freek, Heinz-Josef Klümpen, Klümpen, van Gulik, Thomas, Erdmann, Joris, de Boer, Marieke, Hoogwater, Frederik, Koerkamp, Bas Groot, Braat, Andries, Verheij, Joanne, Nagtegaal, Iris, van Laarhoven, Cornelis, van den Boezem, Peter, van der Post, Rachel, and de Reuver, Philip
- Published
- 2020
23. Trends in Treatment and Survival of Gallbladder Cancer in the Netherlands; Identifying Gaps and Opportunities from a Nation-Wide Cohort
- Author
-
de Savornin Lohman, Elise, de Bitter, Tessa, Verhoeven, Rob, van der Geest, Lydia, Hagendoorn, Jeroen, Mohammad, Nadia Haj, Daams, Freek, Heinz-Josef Klümpen, Klümpen, van Gulik, Thomas, Erdmann, Joris, de Boer, Marieke, Hoogwater, Frederik, Koerkamp, Bas Groot, Braat, Andries, Verheij, Joanne, Nagtegaal, Iris, van Laarhoven, Cornelis, van den Boezem, Peter, van der Post, Rachel, de Reuver, Philip, de Savornin Lohman, Elise, de Bitter, Tessa, Verhoeven, Rob, van der Geest, Lydia, Hagendoorn, Jeroen, Mohammad, Nadia Haj, Daams, Freek, Heinz-Josef Klümpen, Klümpen, van Gulik, Thomas, Erdmann, Joris, de Boer, Marieke, Hoogwater, Frederik, Koerkamp, Bas Groot, Braat, Andries, Verheij, Joanne, Nagtegaal, Iris, van Laarhoven, Cornelis, van den Boezem, Peter, van der Post, Rachel, and de Reuver, Philip
- Published
- 2020
24. Severe Salmonella spp. or Campylobacter spp. Infection and the Risk of Biliary Tract Cancer: A Population-Based Study
- Author
-
IRAS OH Epidemiology Microbial Agents, dIRAS RA-I&I I&I, de Savornin Lohman, Elise, Duijster, Janneke, Groot Koerkamp, Bas, van der Post, Rachel, Franz, Eelco, Mughini Gras, Lapo, de Reuver, Philip, IRAS OH Epidemiology Microbial Agents, dIRAS RA-I&I I&I, de Savornin Lohman, Elise, Duijster, Janneke, Groot Koerkamp, Bas, van der Post, Rachel, Franz, Eelco, Mughini Gras, Lapo, and de Reuver, Philip
- Published
- 2020
25. Trends in Treatment and Survival of Gallbladder Cancer in the Netherlands; Identifying Gaps and Opportunities from a Nation-Wide Cohort
- Author
-
MS CGO, Cancer, MS Medische Oncologie, de Savornin Lohman, Elise, de Bitter, Tessa, Verhoeven, Rob, van der Geest, Lydia, Hagendoorn, Jeroen, Mohammad, Nadia Haj, Daams, Freek, Heinz-Josef Klümpen, Klümpen, van Gulik, Thomas, Erdmann, Joris, de Boer, Marieke, Hoogwater, Frederik, Koerkamp, Bas Groot, Braat, Andries, Verheij, Joanne, Nagtegaal, Iris, van Laarhoven, Cornelis, van den Boezem, Peter, van der Post, Rachel, de Reuver, Philip, MS CGO, Cancer, MS Medische Oncologie, de Savornin Lohman, Elise, de Bitter, Tessa, Verhoeven, Rob, van der Geest, Lydia, Hagendoorn, Jeroen, Mohammad, Nadia Haj, Daams, Freek, Heinz-Josef Klümpen, Klümpen, van Gulik, Thomas, Erdmann, Joris, de Boer, Marieke, Hoogwater, Frederik, Koerkamp, Bas Groot, Braat, Andries, Verheij, Joanne, Nagtegaal, Iris, van Laarhoven, Cornelis, van den Boezem, Peter, van der Post, Rachel, and de Reuver, Philip
- Published
- 2020
26. Severe Salmonella spp. or Campylobacter spp. Infection and the Risk of Biliary Tract Cancer: A Population-Based Study
- Author
-
IRAS OH Epidemiology Microbial Agents, dIRAS RA-I&I I&I, de Savornin Lohman, Elise, Duijster, Janneke, Groot Koerkamp, Bas, van der Post, Rachel, Franz, Eelco, Mughini Gras, Lapo, de Reuver, Philip, IRAS OH Epidemiology Microbial Agents, dIRAS RA-I&I I&I, de Savornin Lohman, Elise, Duijster, Janneke, Groot Koerkamp, Bas, van der Post, Rachel, Franz, Eelco, Mughini Gras, Lapo, and de Reuver, Philip
- Published
- 2020
27. Should jaundice preclude resection in patients with gallbladder cancer? Results from a nation-wide cohort study
- Author
-
Divisie Beeld & Oncologie, MS CGO, Cancer, de Savornin Lohman, Elise A.J., Kuipers, Hendrien, van Dooren, Mike, Verhoeven, Rob H.A., Erdmann, Joris I., Groot Koerkamp, Bas, Braat, Andries E., Hagendoorn, Jeroen, Daams, Freek, van Dam, Ronald, van Gulik, Thomas M., de Boer, Marieke T., de Reuver, Philip R., Divisie Beeld & Oncologie, MS CGO, Cancer, de Savornin Lohman, Elise A.J., Kuipers, Hendrien, van Dooren, Mike, Verhoeven, Rob H.A., Erdmann, Joris I., Groot Koerkamp, Bas, Braat, Andries E., Hagendoorn, Jeroen, Daams, Freek, van Dam, Ronald, van Gulik, Thomas M., de Boer, Marieke T., and de Reuver, Philip R.
- Published
- 2020
28. Systematic review of published literature on oxaliplatin and mitomycin C as chemotherapeutic agents for hyperthermic intraperitoneal chemotherapy in patients with peritoneal metastases from colorectal cancer
- Author
-
Wisselink, Daan D, Braakhuis, Linde L F, Gallo, Gaetano, van Grevenstein, Wilhelmina M U, van Dieren, Susan, Kok, Niels F M, de Reuver, Philip R, Tanis, Pieter J, de Hingh, Ignace H J T, Wisselink, Daan D, Braakhuis, Linde L F, Gallo, Gaetano, van Grevenstein, Wilhelmina M U, van Dieren, Susan, Kok, Niels F M, de Reuver, Philip R, Tanis, Pieter J, and de Hingh, Ignace H J T
- Published
- 2019
29. Systematic review of published literature on oxaliplatin and mitomycin C as chemotherapeutic agents for hyperthermic intraperitoneal chemotherapy in patients with peritoneal metastases from colorectal cancer
- Author
-
Wisselink, Daan D, Braakhuis, Linde L F, Gallo, Gaetano, van Grevenstein, Wilhelmina M U, van Dieren, Susan, Kok, Niels F M, de Reuver, Philip R, Tanis, Pieter J, de Hingh, Ignace H J T, Wisselink, Daan D, Braakhuis, Linde L F, Gallo, Gaetano, van Grevenstein, Wilhelmina M U, van Dieren, Susan, Kok, Niels F M, de Reuver, Philip R, Tanis, Pieter J, and de Hingh, Ignace H J T
- Published
- 2019
30. Systematic review of published literature on oxaliplatin and mitomycin C as chemotherapeutic agents for hyperthermic intraperitoneal chemotherapy in patients with peritoneal metastases from colorectal cancer
- Author
-
Wisselink, Daan D, Braakhuis, Linde L F, Gallo, Gaetano, van Grevenstein, Wilhelmina M U, van Dieren, Susan, Kok, Niels F M, de Reuver, Philip R, Tanis, Pieter J, de Hingh, Ignace H J T, Wisselink, Daan D, Braakhuis, Linde L F, Gallo, Gaetano, van Grevenstein, Wilhelmina M U, van Dieren, Susan, Kok, Niels F M, de Reuver, Philip R, Tanis, Pieter J, and de Hingh, Ignace H J T
- Published
- 2019
31. Systematic review of published literature on oxaliplatin and mitomycin C as chemotherapeutic agents for hyperthermic intraperitoneal chemotherapy in patients with peritoneal metastases from colorectal cancer
- Author
-
MS CGO, Cancer, Wisselink, Daan D, Braakhuis, Linde L F, Gallo, Gaetano, van Grevenstein, Wilhelmina M U, van Dieren, Susan, Kok, Niels F M, de Reuver, Philip R, Tanis, Pieter J, de Hingh, Ignace H J T, MS CGO, Cancer, Wisselink, Daan D, Braakhuis, Linde L F, Gallo, Gaetano, van Grevenstein, Wilhelmina M U, van Dieren, Susan, Kok, Niels F M, de Reuver, Philip R, Tanis, Pieter J, and de Hingh, Ignace H J T
- Published
- 2019
Catalog
Books, media, physical & digital resources
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.