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2. Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants
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Zhou, B, Carrillo-Larco, RM, Danaei, G, Riley, LM, Paciorek, CJ, Stevens, GA, Gregg, EW, Bennett, JE, Solomon, B, Singleton, RK, Sophiea, MK, Iurilli, MLC, Lhoste, VPF, Cowan, MJ, Savin, S, Woodward, M, Balanova, Y, Cifkova, R, Damasceno, A, Elliott, P, Farzadfar, F, He, J, Ikeda, N, Kengne, AP, Khang, Y-H, Kim, HC, Laxmaiah, A, Lin, H-H, Margozzini Maira, P, Miranda, JJ, Neuhauser, H, Sundström, J, Varghese, C, Widyahening, IS, Zdrojewski, T, Abarca-Gómez, L, Abdeen, ZA, Abdul Rahim, HF, Abu-Rmeileh, NM, Acosta-Cazares, B, Adams, RJ, Aekplakorn, W, Afsana, K, Afzal, S, Agdeppa, IA, Aghazadeh-Attari, J, Aguilar-Salinas, CA, Agyemang, C, Ahmad, NA, Ahmadi, A, Ahmadi, N, Ahmadizar, F, Ahmed, SH, Ahrens, W, Ajlouni, K, Al-Raddadi, R, Alarouj, M, AlBuhairan, F, AlDhukair, S, Ali, MM, Alkandari, A, Alkerwi, A, Allin, K, Aly, E, Amarapurkar, DN, Amougou, N, Amouyel, P, Andersen, LB, Anderssen, SA, Anjana, RM, Ansari-Moghaddam, A, Ansong, D, Aounallah-Skhiri, H, Araújo, J, Ariansen, I, Aris, T, Arku, RE, Arlappa, N, Aryal, KK, Aspelund, T, Assah, FK, Assunção, MCF, Auvinen, J, Avdićová, M, Azevedo, A, Azimi-Nezhad, M, Azizi, F, Azmin, M, Babu, BV, Bahijri, S, Balakrishna, N, Bamoshmoosh, M, Banach, M, Banadinović, M, Bandosz, P, Banegas, JR, Baran, J, Barbagallo, CM, Barceló, A, Barkat, A, Barreto, M, Barros, AJD, Barros, MVG, Bartosiewicz, A, Basit, A, Bastos, JLD, Bata, I, Batieha, AM, Batyrbek, A, Baur, LA, Beaglehole, R, Belavendra, A, Ben Romdhane, H, Benet, M, Benson, LS, Berkinbayev, S, Bernabe-Ortiz, A, Bernotiene, G, Bettiol, H, Bezerra, J, Bhagyalaxmi, A, Bhargava, SK, Bia, D, Biasch, K, Bika Lele, EC, Bikbov, MM, Bista, B, Bjerregaard, P, Bjertness, E, Bjertness, MB, Björkelund, C, Bloch, KV, Blokstra, A, Bo, S, Bobak, M, Boeing, H, Boggia, JG, Boissonnet, CP, Bojesen, SE, Bongard, V, Bonilla-Vargas, A, Bopp, M, Borghs, H, Bovet, P, Boyer, CB, Braeckman, L, Brajkovich, I, Branca, F, Breckenkamp, J, Brenner, H, Brewster, LM, Briceño, Y, Brito, M, Bruno, G, Bueno-de-Mesquita, HB, Bueno, G, Bugge, A, Burns, C, Bursztyn, M, Cabrera de León, A, Cacciottolo, J, Cameron, C, Can, G, Cândido, APC, Capanzana, MV, Čapková, N, Capuano, E, Capuano, V, Cardoso, VC, Carlsson, AC, Carvalho, J, Casanueva, FF, Censi, L, Cervantes-Loaiza, M, Chadjigeorgiou, CA, Chamukuttan, S, Chan, AW, Chan, Q, Chaturvedi, HK, Chaturvedi, N, Chee, ML, Chen, C-J, Chen, F, Chen, H, Chen, S, Chen, Z, Cheng, C-Y, Cheraghian, B, Cherkaoui Dekkaki, I, Chetrit, A, Chien, K-L, Chiolero, A, Chiou, S-T, Chirita-Emandi, A, Chirlaque, M-D, Cho, B, Christensen, K, Christofaro, DG, Chudek, J, Cinteza, E, Claessens, F, Clarke, J, Clays, E, Cohen, E, Concin, H, Cooper, C, Coppinger, TC, Costanzo, S, Cottel, D, Cowell, C, Craig, CL, Crampin, AC, Crujeiras, AB, Cruz, JJ, Csilla, S, Cui, L, Cureau, FV, Cuschieri, S, D'Arrigo, G, d'Orsi, E, Dallongeville, J, Dankner, R, Dantoft, TM, Dauchet, L, Davletov, K, De Backer, G, De Bacquer, D, De Curtis, A, de Gaetano, G, De Henauw, S, de Oliveira, PD, De Ridder, D, De Smedt, D, Deepa, M, Deev, AD, DeGennaro, VJ, Delisle, H, Demarest, S, Dennison, E, Deschamps, V, Dhimal, M, Di Castelnuovo, AF, Dias-da-Costa, JS, Diaz, A, Dickerson, TT, Dika, Z, Djalalinia, S, Do, HTP, Dobson, AJ, Donfrancesco, C, Donoso, SP, Döring, A, Dorobantu, M, Dörr, M, Doua, K, Dragano, N, Drygas, W, Duante, CA, Duboz, P, Duda, RB, Dulskiene, V, Dushpanova, A, Džakula, A, Dzerve, V, Dziankowska-Zaborszczyk, E, Eddie, R, Eftekhar, E, Eggertsen, R, Eghtesad, S, Eiben, G, Ekelund, U, El-Khateeb, M, El Ati, J, Eldemire-Shearer, D, Eliasen, M, Elosua, R, Erasmus, RT, Erbel, R, Erem, C, Eriksen, L, Eriksson, JG, Escobedo-de la Peña, J, Eslami, S, Esmaeili, A, Evans, A, Faeh, D, Fakhretdinova, AA, Fall, CH, Faramarzi, E, Farjam, M, Fattahi, MR, Fawwad, A, Felix-Redondo, FJ, Felix, SB, Ferguson, TS, Fernandes, RA, Fernández-Bergés, D, Ferrante, D, Ferrao, T, Ferrari, M, Ferrario, MM, Ferreccio, C, Ferreira, HS, Ferrer, E, Ferrieres, J, Figueiró, TH, Fink, G, Fischer, K, Foo, LH, Forsner, M, Fouad, HM, Francis, DK, Franco, MDC, Frikke-Schmidt, R, Frontera, G, Fuchs, FD, Fuchs, SC, Fujita, Y, Fumihiko, M, Furdela, V, Furer, A, Furusawa, T, Gaciong, Z, Galbarczyk, A, Galenkamp, H, Galvano, F, Gao, J, Gao, P, Garcia-de-la-Hera, M, Garcia, P, Gareta, D, Garnett, SP, Gaspoz, J-M, Gasull, M, Gazzinelli, A, Gehring, U, Geleijnse, JM, George, R, Ghanbari, A, Ghasemi, E, Gheorghe-Fronea, O-F, Ghimire, A, Gialluisi, A, Giampaoli, S, Gieger, C, Gill, TK, Giovannelli, J, Gironella, G, Giwercman, A, Gkiouras, K, Goldberg, M, Goldsmith, RA, Gomez, LF, Gomula, A, Gonçalves, H, Gonçalves, M, Gonçalves Cordeiro da Silva, B, Gonzalez-Chica, DA, Gonzalez-Gross, M, González-Rivas, JP, González-Villalpando, C, González-Villalpando, M-E, Gonzalez, AR, Gorbea, MB, Gottrand, F, Graff-Iversen, S, Grafnetter, D, Grajda, A, Grammatikopoulou, MG, Gregor, RD, Grodzicki, T, Grosso, G, Gruden, G, Gu, D, Guan, OP, Gudmundsson, EF, Gudnason, V, Guerrero, R, Guessous, I, Guimaraes, AL, Gulliford, MC, Gunnlaugsdottir, J, Gunter, MJ, Gupta, PC, Gupta, R, Gureje, O, Gurzkowska, B, Gutierrez, L, Gutzwiller, F, Ha, S, Hadaegh, F, Haghshenas, R, Hakimi, H, Halkjær, J, Hambleton, IR, Hamzeh, B, Hange, D, Hanif, AAM, Hantunen, S, Hao, J, Hardman, CM, Hari Kumar, R, Hashemi-Shahri, SM, Hata, J, Haugsgjerd, T, Hayes, AJ, He, Y, Heier, M, Hendriks, ME, Henrique, RDS, Henriques, A, Hernandez Cadena, L, Herqutanto, Herrala, S, Heshmat, R, Hill, AG, Ho, SY, Ho, SC, Hobbs, M, Holdsworth, M, Homayounfar, R, Horasan Dinc, G, Horimoto, ARVR, Hormiga, CM, Horta, BL, Houti, L, Howitt, C, Htay, TT, Htet, AS, Htike, MMT, Hu, Y, Huerta, JM, Huhtaniemi, IT, Huiart, L, Huisman, M, Husseini, AS, Huybrechts, I, Hwalla, N, Iacoviello, L, Iannone, AG, Ibrahim, MM, Ibrahim Wong, N, Ikram, MA, Iotova, V, Irazola, VE, Ishida, T, Isiguzo, GC, Islam, M, Islam, SMS, Iwasaki, M, Jackson, RT, Jacobs, JM, Jaddou, HY, Jafar, T, James, K, Jamrozik, K, Janszky, I, Janus, E, Jarvelin, M-R, Jasienska, G, Jelaković, A, Jelaković, B, Jennings, G, Jha, AK, Jiang, CQ, Jimenez, RO, Jöckel, K-H, Joffres, M, Johansson, M, Jokelainen, JJ, Jonas, JB, Jørgensen, T, Joshi, P, Joukar, F, Jóżwiak, J, Juolevi, A, Jurak, G, Jureša, V, Kaaks, R, Kafatos, A, Kajantie, EO, Kalmatayeva, Z, Kalpourtzi, N, Kalter-Leibovici, O, Kampmann, FB, Kannan, S, Karaglani, E, Kårhus, LL, Karki, KB, Katibeh, M, Katz, J, Kauhanen, J, Kaur, P, Kavousi, M, Kazakbaeva, GM, Keil, U, Keinan Boker, L, Keinänen-Kiukaanniemi, S, Kelishadi, R, Kemper, HCG, Keramati, M, Kerimkulova, A, Kersting, M, Key, T, Khader, YS, Khalili, D, Khaw, K-T, Kheiri, B, Kheradmand, M, Khosravi, A, Kiechl-Kohlendorfer, U, Kiechl, S, Killewo, J, Kim, DW, Kim, J, Klakk, H, Klimek, M, Klumbiene, J, Knoflach, M, Kolle, E, Kolsteren, P, Kontto, JP, Korpelainen, R, Korrovits, P, Kos, J, Koskinen, S, Kouda, K, Kowlessur, S, Koziel, S, Kratenova, J, Kriaucioniene, V, Kristensen, PL, Krokstad, S, Kromhout, D, Kruger, HS, Kubinova, R, Kuciene, R, Kujala, UM, Kulaga, Z, Kumar, RK, Kurjata, P, Kusuma, YS, Kutsenko, V, Kuulasmaa, K, Kyobutungi, C, Laatikainen, T, Lachat, C, Laid, Y, Lam, TH, Landrove, O, Lanska, V, Lappas, G, Larijani, B, Latt, TS, Le Coroller, G, Le Nguyen Bao, K, Le, TD, Lee, J, Lehmann, N, Lehtimäki, T, Lemogoum, D, Levitt, NS, Li, Y, Lilly, CL, Lim, W-Y, Lima-Costa, MF, Lin, X, Lin, Y-T, Lind, L, Lingam, V, Linneberg, A, Lissner, L, Litwin, M, Lo, W-C, Loit, H-M, Lopez-Garcia, E, Lopez, T, Lotufo, PA, Lozano, JE, Lukačević Lovrenčić, I, Lukrafka, JL, Luksiene, D, Lundqvist, A, Lundqvist, R, Lunet, N, Lustigová, M, Luszczki, E, Ma, G, Ma, J, Machado-Coelho, GLL, Machado-Rodrigues, AM, Macia, E, Macieira, LM, Madar, AA, Maggi, S, Magliano, DJ, Magriplis, E, Mahasampath, G, Maire, B, Majer, M, Makdisse, M, Malekzadeh, F, Malekzadeh, R, Malhotra, R, Mallikharjuna Rao, K, Malyutina, SK, Maniego, LV, Manios, Y, Mann, JI, Mansour-Ghanaei, F, Manzato, E, Marcil, A, Mårild, SB, Marinović Glavić, M, Marques-Vidal, P, Marques, LP, Marrugat, J, Martorell, R, Mascarenhas, LP, Matasin, M, Mathiesen, EB, Mathur, P, Matijasevich, A, Matlosz, P, Matsha, TE, Mavrogianni, C, Mbanya, JCN, Mc Donald Posso, AJ, McFarlane, SR, McGarvey, ST, McLachlan, S, McLean, RM, McLean, SB, McNulty, BA, Mediene Benchekor, S, Medzioniene, J, Mehdipour, P, Mehlig, K, Mehrparvar, AH, Meirhaeghe, A, Meisinger, C, Mendoza Montano, C, Menezes, AMB, Menon, GR, Mereke, A, Meshram, II, Metspalu, A, Meyer, HE, Mi, J, Michels, N, Mikkel, K, Milkowska, K, Miller, JC, Minderico, CS, Mini, GK, Mirjalili, MR, Mirrakhimov, E, Mišigoj-Duraković, M, Modesti, PA, Moghaddam, SS, Mohajer, B, Mohamed, MK, Mohamed, SF, Mohammad, K, Mohammadi, MR, Mohammadi, Z, Mohammadifard, N, Mohammadpourhodki, R, Mohan, V, Mohanna, S, Mohd Yusoff, MF, Mohebbi, I, Mohebi, F, Moitry, M, Møllehave, LT, Molnár, D, Momenan, A, Mondo, CK, Monterrubio-Flores, E, Monyeki, KDK, Moon, JS, Moosazadeh, M, Moreira, LB, Morejon, A, Moreno, LA, Morgan, K, Moschonis, G, Mossakowska, M, Mostafa, A, Mostafavi, S-A, Mota, J, Motlagh, ME, Motta, J, Moura-dos-Santos, MA, Mridha, MK, Msyamboza, KP, Mu, TT, Muhihi, AJ, Muiesan, ML, Müller-Nurasyid, M, Murphy, N, Mursu, J, Musa, KI, Musić Milanović, S, Musil, V, Mustafa, N, Nabipour, I, Naderimagham, S, Nagel, G, Naidu, BM, Najafi, F, Nakamura, H, Námešná, J, Nang, EEK, Nangia, VB, Narake, S, Ndiaye, NC, Neal, WA, Nejatizadeh, A, Nenko, I, Neovius, M, Nguyen, CT, Nguyen, ND, Nguyen, QV, Nguyen, QN, Nieto-Martínez, RE, Niiranen, TJ, Nikitin, YP, Ninomiya, T, Nishtar, S, Njelekela, MA, Noale, M, Noboa, OA, Noorbala, AA, Norat, T, Nordendahl, M, Nordestgaard, BG, Noto, D, Nowak-Szczepanska, N, Nsour, MA, Nunes, B, O'Neill, TW, O'Reilly, D, Ochimana, C, Oda, E, Odili, AN, Oh, K, Ohara, K, Ohtsuka, R, Olié, V, Olinto, MTA, Oliveira, IO, Omar, MA, Onat, A, Ong, SK, Ono, LM, Ordunez, P, Ornelas, R, Ortiz, PJ, Osmond, C, Ostojic, SM, Ostovar, A, Otero, JA, Overvad, K, Owusu-Dabo, E, Paccaud, FM, Padez, C, Pahomova, E, Paiva, KMD, Pająk, A, Palli, D, Palmieri, L, Pan, W-H, Panda-Jonas, S, Panza, F, Paoli, M, Papandreou, D, Park, S-W, Park, S, Parnell, WR, Parsaeian, M, Pasquet, P, Patel, ND, Pavlyshyn, H, Pećin, I, Pednekar, MS, Pedro, JM, Peer, N, Peixoto, SV, Peltonen, M, Pereira, AC, Peres, KGDA, Peres, MA, Peters, A, Petkeviciene, J, Peykari, N, Pham, ST, Pichardo, RN, Pigeot, I, Pikhart, H, Pilav, A, Pilotto, L, Pitakaka, F, Piwonska, A, Pizarro, AN, Plans-Rubió, P, Polašek, O, Porta, M, Poudyal, A, Pourfarzi, F, Pourshams, A, Poustchi, H, Pradeepa, R, Price, AJ, Price, JF, Providencia, R, Puhakka, SE, Puiu, M, Punab, M, Qasrawi, RF, Qorbani, M, Queiroz, D, Quoc Bao, T, Radić, I, Radisauskas, R, Rahimikazerooni, S, Rahman, M, Raitakari, O, Raj, M, Rakhimova, EM, Ra, Zhou, B, Carrillo-Larco, RM, Danaei, G, Riley, LM, Paciorek, CJ, Stevens, GA, Gregg, EW, Bennett, JE, Solomon, B, Singleton, RK, Sophiea, MK, Iurilli, MLC, Lhoste, VPF, Cowan, MJ, Savin, S, Woodward, M, Balanova, Y, Cifkova, R, Damasceno, A, Elliott, P, Farzadfar, F, He, J, Ikeda, N, Kengne, AP, Khang, Y-H, Kim, HC, Laxmaiah, A, Lin, H-H, Margozzini Maira, P, Miranda, JJ, Neuhauser, H, Sundström, J, Varghese, C, Widyahening, IS, Zdrojewski, T, Abarca-Gómez, L, Abdeen, ZA, Abdul Rahim, HF, Abu-Rmeileh, NM, Acosta-Cazares, B, Adams, RJ, Aekplakorn, W, Afsana, K, Afzal, S, Agdeppa, IA, Aghazadeh-Attari, J, Aguilar-Salinas, CA, Agyemang, C, Ahmad, NA, Ahmadi, A, Ahmadi, N, Ahmadizar, F, Ahmed, SH, Ahrens, W, Ajlouni, K, Al-Raddadi, R, Alarouj, M, AlBuhairan, F, AlDhukair, S, Ali, MM, Alkandari, A, Alkerwi, A, Allin, K, Aly, E, Amarapurkar, DN, Amougou, N, Amouyel, P, Andersen, LB, Anderssen, SA, Anjana, RM, Ansari-Moghaddam, A, Ansong, D, Aounallah-Skhiri, H, Araújo, J, Ariansen, I, Aris, T, Arku, RE, Arlappa, N, Aryal, KK, Aspelund, T, Assah, FK, Assunção, MCF, Auvinen, J, Avdićová, M, Azevedo, A, Azimi-Nezhad, M, Azizi, F, Azmin, M, Babu, BV, Bahijri, S, Balakrishna, N, Bamoshmoosh, M, Banach, M, Banadinović, M, Bandosz, P, Banegas, JR, Baran, J, Barbagallo, CM, Barceló, A, Barkat, A, Barreto, M, Barros, AJD, Barros, MVG, Bartosiewicz, A, Basit, A, Bastos, JLD, Bata, I, Batieha, AM, Batyrbek, A, Baur, LA, Beaglehole, R, Belavendra, A, Ben Romdhane, H, Benet, M, Benson, LS, Berkinbayev, S, Bernabe-Ortiz, A, Bernotiene, G, Bettiol, H, Bezerra, J, Bhagyalaxmi, A, Bhargava, SK, Bia, D, Biasch, K, Bika Lele, EC, Bikbov, MM, Bista, B, Bjerregaard, P, Bjertness, E, Bjertness, MB, Björkelund, C, Bloch, KV, Blokstra, A, Bo, S, Bobak, M, Boeing, H, Boggia, JG, Boissonnet, CP, Bojesen, SE, Bongard, V, Bonilla-Vargas, A, Bopp, M, Borghs, H, Bovet, P, Boyer, CB, Braeckman, L, Brajkovich, I, Branca, F, Breckenkamp, J, Brenner, H, Brewster, LM, Briceño, Y, Brito, M, Bruno, G, Bueno-de-Mesquita, HB, Bueno, G, Bugge, A, Burns, C, Bursztyn, M, Cabrera de León, A, Cacciottolo, J, Cameron, C, Can, G, Cândido, APC, Capanzana, MV, Čapková, N, Capuano, E, Capuano, V, Cardoso, VC, Carlsson, AC, Carvalho, J, Casanueva, FF, Censi, L, Cervantes-Loaiza, M, Chadjigeorgiou, CA, Chamukuttan, S, Chan, AW, Chan, Q, Chaturvedi, HK, Chaturvedi, N, Chee, ML, Chen, C-J, Chen, F, Chen, H, Chen, S, Chen, Z, Cheng, C-Y, Cheraghian, B, Cherkaoui Dekkaki, I, Chetrit, A, Chien, K-L, Chiolero, A, Chiou, S-T, Chirita-Emandi, A, Chirlaque, M-D, Cho, B, Christensen, K, Christofaro, DG, Chudek, J, Cinteza, E, Claessens, F, Clarke, J, Clays, E, Cohen, E, Concin, H, Cooper, C, Coppinger, TC, Costanzo, S, Cottel, D, Cowell, C, Craig, CL, Crampin, AC, Crujeiras, AB, Cruz, JJ, Csilla, S, Cui, L, Cureau, FV, Cuschieri, S, D'Arrigo, G, d'Orsi, E, Dallongeville, J, Dankner, R, Dantoft, TM, Dauchet, L, Davletov, K, De Backer, G, De Bacquer, D, De Curtis, A, de Gaetano, G, De Henauw, S, de Oliveira, PD, De Ridder, D, De Smedt, D, Deepa, M, Deev, AD, DeGennaro, VJ, Delisle, H, Demarest, S, Dennison, E, Deschamps, V, Dhimal, M, Di Castelnuovo, AF, Dias-da-Costa, JS, Diaz, A, Dickerson, TT, Dika, Z, Djalalinia, S, Do, HTP, Dobson, AJ, Donfrancesco, C, Donoso, SP, Döring, A, Dorobantu, M, Dörr, M, Doua, K, Dragano, N, Drygas, W, Duante, CA, Duboz, P, Duda, RB, Dulskiene, V, Dushpanova, A, Džakula, A, Dzerve, V, Dziankowska-Zaborszczyk, E, Eddie, R, Eftekhar, E, Eggertsen, R, Eghtesad, S, Eiben, G, Ekelund, U, El-Khateeb, M, El Ati, J, Eldemire-Shearer, D, Eliasen, M, Elosua, R, Erasmus, RT, Erbel, R, Erem, C, Eriksen, L, Eriksson, JG, Escobedo-de la Peña, J, Eslami, S, Esmaeili, A, Evans, A, Faeh, D, Fakhretdinova, AA, Fall, CH, Faramarzi, E, Farjam, M, Fattahi, MR, Fawwad, A, Felix-Redondo, FJ, Felix, SB, Ferguson, TS, Fernandes, RA, Fernández-Bergés, D, Ferrante, D, Ferrao, T, Ferrari, M, Ferrario, MM, Ferreccio, C, Ferreira, HS, Ferrer, E, Ferrieres, J, Figueiró, TH, Fink, G, Fischer, K, Foo, LH, Forsner, M, Fouad, HM, Francis, DK, Franco, MDC, Frikke-Schmidt, R, Frontera, G, Fuchs, FD, Fuchs, SC, Fujita, Y, Fumihiko, M, Furdela, V, Furer, A, Furusawa, T, Gaciong, Z, Galbarczyk, A, Galenkamp, H, Galvano, F, Gao, J, Gao, P, Garcia-de-la-Hera, M, Garcia, P, Gareta, D, Garnett, SP, Gaspoz, J-M, Gasull, M, Gazzinelli, A, Gehring, U, Geleijnse, JM, George, R, Ghanbari, A, Ghasemi, E, Gheorghe-Fronea, O-F, Ghimire, A, Gialluisi, A, Giampaoli, S, Gieger, C, Gill, TK, Giovannelli, J, Gironella, G, Giwercman, A, Gkiouras, K, Goldberg, M, Goldsmith, RA, Gomez, LF, Gomula, A, Gonçalves, H, Gonçalves, M, Gonçalves Cordeiro da Silva, B, Gonzalez-Chica, DA, Gonzalez-Gross, M, González-Rivas, JP, González-Villalpando, C, González-Villalpando, M-E, Gonzalez, AR, Gorbea, MB, Gottrand, F, Graff-Iversen, S, Grafnetter, D, Grajda, A, Grammatikopoulou, MG, Gregor, RD, Grodzicki, T, Grosso, G, Gruden, G, Gu, D, Guan, OP, Gudmundsson, EF, Gudnason, V, Guerrero, R, Guessous, I, Guimaraes, AL, Gulliford, MC, Gunnlaugsdottir, J, Gunter, MJ, Gupta, PC, Gupta, R, Gureje, O, Gurzkowska, B, Gutierrez, L, Gutzwiller, F, Ha, S, Hadaegh, F, Haghshenas, R, Hakimi, H, Halkjær, J, Hambleton, IR, Hamzeh, B, Hange, D, Hanif, AAM, Hantunen, S, Hao, J, Hardman, CM, Hari Kumar, R, Hashemi-Shahri, SM, Hata, J, Haugsgjerd, T, Hayes, AJ, He, Y, Heier, M, Hendriks, ME, Henrique, RDS, Henriques, A, Hernandez Cadena, L, Herqutanto, Herrala, S, Heshmat, R, Hill, AG, Ho, SY, Ho, SC, Hobbs, M, Holdsworth, M, Homayounfar, R, Horasan Dinc, G, Horimoto, ARVR, Hormiga, CM, Horta, BL, Houti, L, Howitt, C, Htay, TT, Htet, AS, Htike, MMT, Hu, Y, Huerta, JM, Huhtaniemi, IT, Huiart, L, Huisman, M, Husseini, AS, Huybrechts, I, Hwalla, N, Iacoviello, L, Iannone, AG, Ibrahim, MM, Ibrahim Wong, N, Ikram, MA, Iotova, V, Irazola, VE, Ishida, T, Isiguzo, GC, Islam, M, Islam, SMS, Iwasaki, M, Jackson, RT, Jacobs, JM, Jaddou, HY, Jafar, T, James, K, Jamrozik, K, Janszky, I, Janus, E, Jarvelin, M-R, Jasienska, G, Jelaković, A, Jelaković, B, Jennings, G, Jha, AK, Jiang, CQ, Jimenez, RO, Jöckel, K-H, Joffres, M, Johansson, M, Jokelainen, JJ, Jonas, JB, Jørgensen, T, Joshi, P, Joukar, F, Jóżwiak, J, Juolevi, A, Jurak, G, Jureša, V, Kaaks, R, Kafatos, A, Kajantie, EO, Kalmatayeva, Z, Kalpourtzi, N, Kalter-Leibovici, O, Kampmann, FB, Kannan, S, Karaglani, E, Kårhus, LL, Karki, KB, Katibeh, M, Katz, J, Kauhanen, J, Kaur, P, Kavousi, M, Kazakbaeva, GM, Keil, U, Keinan Boker, L, Keinänen-Kiukaanniemi, S, Kelishadi, R, Kemper, HCG, Keramati, M, Kerimkulova, A, Kersting, M, Key, T, Khader, YS, Khalili, D, Khaw, K-T, Kheiri, B, Kheradmand, M, Khosravi, A, Kiechl-Kohlendorfer, U, Kiechl, S, Killewo, J, Kim, DW, Kim, J, Klakk, H, Klimek, M, Klumbiene, J, Knoflach, M, Kolle, E, Kolsteren, P, Kontto, JP, Korpelainen, R, Korrovits, P, Kos, J, Koskinen, S, Kouda, K, Kowlessur, S, Koziel, S, Kratenova, J, Kriaucioniene, V, Kristensen, PL, Krokstad, S, Kromhout, D, Kruger, HS, Kubinova, R, Kuciene, R, Kujala, UM, Kulaga, Z, Kumar, RK, Kurjata, P, Kusuma, YS, Kutsenko, V, Kuulasmaa, K, Kyobutungi, C, Laatikainen, T, Lachat, C, Laid, Y, Lam, TH, Landrove, O, Lanska, V, Lappas, G, Larijani, B, Latt, TS, Le Coroller, G, Le Nguyen Bao, K, Le, TD, Lee, J, Lehmann, N, Lehtimäki, T, Lemogoum, D, Levitt, NS, Li, Y, Lilly, CL, Lim, W-Y, Lima-Costa, MF, Lin, X, Lin, Y-T, Lind, L, Lingam, V, Linneberg, A, Lissner, L, Litwin, M, Lo, W-C, Loit, H-M, Lopez-Garcia, E, Lopez, T, Lotufo, PA, Lozano, JE, Lukačević Lovrenčić, I, Lukrafka, JL, Luksiene, D, Lundqvist, A, Lundqvist, R, Lunet, N, Lustigová, M, Luszczki, E, Ma, G, Ma, J, Machado-Coelho, GLL, Machado-Rodrigues, AM, Macia, E, Macieira, LM, Madar, AA, Maggi, S, Magliano, DJ, Magriplis, E, Mahasampath, G, Maire, B, Majer, M, Makdisse, M, Malekzadeh, F, Malekzadeh, R, Malhotra, R, Mallikharjuna Rao, K, Malyutina, SK, Maniego, LV, Manios, Y, Mann, JI, Mansour-Ghanaei, F, Manzato, E, Marcil, A, Mårild, SB, Marinović Glavić, M, Marques-Vidal, P, Marques, LP, Marrugat, J, Martorell, R, Mascarenhas, LP, Matasin, M, Mathiesen, EB, Mathur, P, Matijasevich, A, Matlosz, P, Matsha, TE, Mavrogianni, C, Mbanya, JCN, Mc Donald Posso, AJ, McFarlane, SR, McGarvey, ST, McLachlan, S, McLean, RM, McLean, SB, McNulty, BA, Mediene Benchekor, S, Medzioniene, J, Mehdipour, P, Mehlig, K, Mehrparvar, AH, Meirhaeghe, A, Meisinger, C, Mendoza Montano, C, Menezes, AMB, Menon, GR, Mereke, A, Meshram, II, Metspalu, A, Meyer, HE, Mi, J, Michels, N, Mikkel, K, Milkowska, K, Miller, JC, Minderico, CS, Mini, GK, Mirjalili, MR, Mirrakhimov, E, Mišigoj-Duraković, M, Modesti, PA, Moghaddam, SS, Mohajer, B, Mohamed, MK, Mohamed, SF, Mohammad, K, Mohammadi, MR, Mohammadi, Z, Mohammadifard, N, Mohammadpourhodki, R, Mohan, V, Mohanna, S, Mohd Yusoff, MF, Mohebbi, I, Mohebi, F, Moitry, M, Møllehave, LT, Molnár, D, Momenan, A, Mondo, CK, Monterrubio-Flores, E, Monyeki, KDK, Moon, JS, Moosazadeh, M, Moreira, LB, Morejon, A, Moreno, LA, Morgan, K, Moschonis, G, Mossakowska, M, Mostafa, A, Mostafavi, S-A, Mota, J, Motlagh, ME, Motta, J, Moura-dos-Santos, MA, Mridha, MK, Msyamboza, KP, Mu, TT, Muhihi, AJ, Muiesan, ML, Müller-Nurasyid, M, Murphy, N, Mursu, J, Musa, KI, Musić Milanović, S, Musil, V, Mustafa, N, Nabipour, I, Naderimagham, S, Nagel, G, Naidu, BM, Najafi, F, Nakamura, H, Námešná, J, Nang, EEK, Nangia, VB, Narake, S, Ndiaye, NC, Neal, WA, Nejatizadeh, A, Nenko, I, Neovius, M, Nguyen, CT, Nguyen, ND, Nguyen, QV, Nguyen, QN, Nieto-Martínez, RE, Niiranen, TJ, Nikitin, YP, Ninomiya, T, Nishtar, S, Njelekela, MA, Noale, M, Noboa, OA, Noorbala, AA, Norat, T, Nordendahl, M, Nordestgaard, BG, Noto, D, Nowak-Szczepanska, N, Nsour, MA, Nunes, B, O'Neill, TW, O'Reilly, D, Ochimana, C, Oda, E, Odili, AN, Oh, K, Ohara, K, Ohtsuka, R, Olié, V, Olinto, MTA, Oliveira, IO, Omar, MA, Onat, A, Ong, SK, Ono, LM, Ordunez, P, Ornelas, R, Ortiz, PJ, Osmond, C, Ostojic, SM, Ostovar, A, Otero, JA, Overvad, K, Owusu-Dabo, E, Paccaud, FM, Padez, C, Pahomova, E, Paiva, KMD, Pająk, A, Palli, D, Palmieri, L, Pan, W-H, Panda-Jonas, S, Panza, F, Paoli, M, Papandreou, D, Park, S-W, Park, S, Parnell, WR, Parsaeian, M, Pasquet, P, Patel, ND, Pavlyshyn, H, Pećin, I, Pednekar, MS, Pedro, JM, Peer, N, Peixoto, SV, Peltonen, M, Pereira, AC, Peres, KGDA, Peres, MA, Peters, A, Petkeviciene, J, Peykari, N, Pham, ST, Pichardo, RN, Pigeot, I, Pikhart, H, Pilav, A, Pilotto, L, Pitakaka, F, Piwonska, A, Pizarro, AN, Plans-Rubió, P, Polašek, O, Porta, M, Poudyal, A, Pourfarzi, F, Pourshams, A, Poustchi, H, Pradeepa, R, Price, AJ, Price, JF, Providencia, R, Puhakka, SE, Puiu, M, Punab, M, Qasrawi, RF, Qorbani, M, Queiroz, D, Quoc Bao, T, Radić, I, Radisauskas, R, Rahimikazerooni, S, Rahman, M, Raitakari, O, Raj, M, Rakhimova, EM, and Ra
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- 2021
3. Genomic and Transcriptomic Analyses of Breast Cancer Primaries and Matched Metastases in AURORA, the Breast International Group (BIG) Molecular Screening Initiative
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Aftimos, P, Oliveira, M, Irrthum, A, Fumagalli, D, Sotiriou, C, Gal-Yam, EN, Robson, ME, Ndozeng, J, Di Leo, A, Ciruelos, EM, de Azambuja, E, Viale, G, Scheepers, ED, Curigliano, G, Bliss, JM, Reis-Filho, JS, Colleoni, M, Balic, M, Cardoso, F, Albanell, J, Duhem, C, Marreaud, S, Romagnoli, D, Rojas, B, Gombos, A, Wildiers, H, Guerrero-Zotano, A, Hall, P, Bonetti, A, Larsson, KF, Degiorgis, M, Khodaverdi, S, Greil, R, Sverrisdottir, A, Paoli, M, Seyll, E, Loibl, S, Linderholm, B, Zoppoli, G, Davidson, NE, Johannsson, OT, Bedard, PL, Loi, S, Knox, S, Cameron, DA, Harbeck, N, Montoya, ML, Brandao, M, Vingiani, A, Caballero, C, Hilbers, FS, Yates, LR, Benelli, M, Venet, D, Piccart, MJ, Aftimos, P, Oliveira, M, Irrthum, A, Fumagalli, D, Sotiriou, C, Gal-Yam, EN, Robson, ME, Ndozeng, J, Di Leo, A, Ciruelos, EM, de Azambuja, E, Viale, G, Scheepers, ED, Curigliano, G, Bliss, JM, Reis-Filho, JS, Colleoni, M, Balic, M, Cardoso, F, Albanell, J, Duhem, C, Marreaud, S, Romagnoli, D, Rojas, B, Gombos, A, Wildiers, H, Guerrero-Zotano, A, Hall, P, Bonetti, A, Larsson, KF, Degiorgis, M, Khodaverdi, S, Greil, R, Sverrisdottir, A, Paoli, M, Seyll, E, Loibl, S, Linderholm, B, Zoppoli, G, Davidson, NE, Johannsson, OT, Bedard, PL, Loi, S, Knox, S, Cameron, DA, Harbeck, N, Montoya, ML, Brandao, M, Vingiani, A, Caballero, C, Hilbers, FS, Yates, LR, Benelli, M, Venet, D, and Piccart, MJ
- Abstract
AURORA aims to study the processes of relapse in metastatic breast cancer (MBC) by performing multi-omics profiling on paired primary tumors and early-course metastases. Among 381 patients (primary tumor and metastasis pairs: 252 targeted gene sequencing, 152 RNA sequencing, 67 single nucleotide polymorphism arrays), we found a driver role for GATA1 and MEN1 somatic mutations. Metastases were enriched in ESR1, PTEN, CDH1, PIK3CA, and RB1 mutations; MDM4 and MYC amplifications; and ARID1A deletions. An increase in clonality was observed in driver genes such as ERBB2 and RB1. Intrinsic subtype switching occurred in 36% of cases. Luminal A/B to HER2-enriched switching was associated with TP53 and/or PIK3CA mutations. Metastases had lower immune score and increased immune-permissive cells. High tumor mutational burden correlated to shorter time to relapse in HR+/HER2- cancers. ESCAT tier I/II alterations were detected in 51% of patients and matched therapy was used in 7%. Integration of multi-omics analyses in clinical practice could affect treatment strategies in MBC. SIGNIFICANCE: The AURORA program, through the genomic and transcriptomic analyses of matched primary and metastatic samples from 381 patients with breast cancer, coupled with prospectively collected clinical data, identified genomic alterations enriched in metastases and prognostic biomarkers. ESCAT tier I/II alterations were detected in more than half of the patients.This article is highlighted in the In This Issue feature, p. 2659.
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- 2021
4. Obsolescenza del sistema donativo?
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De Paoli M, Manfredi G, Pavesi A S, Tallacchini M, Vendramini E A, Renda, Andrea, Renda, Andrea (ORCID:0000-0001-9669-9730), De Paoli M, Manfredi G, Pavesi A S, Tallacchini M, Vendramini E A, Renda, Andrea, and Renda, Andrea (ORCID:0000-0001-9669-9730)
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The essay deals with the phenomenon of ‘new philanthropy’ from a juridical point of view, wondering if Italian civil law that rules the contract of donation is able to reach a fair balance between the interests of donors and those of donees. Some legal scholars reckon that there are too many limits to the act of donation, such as those arising from the constraint of a solemn form and above all those related to forced heirship (‘successione necessaria’), according to which an indefeasible portion of the estate passes to the deceased’s next-of-kin. On the contrary, the author argues the reasons why these limits aim, on the one hand, to make the donor aware of the seriousness of the choice of undergoing a pauperization, and, on the other, to fulfil the constitutional protection of the nuclear family. Moreover, although forced heirs can use a specific legal action (called ‘azione di riduzione’) that permits them to restore the reserved portion, donations can be abated only after the testamentary dispositions exceeding the disposable portion have been reduced.
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- 2017
5. Obsolescenza del sistema donativo?
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De Paoli M, Manfredi G, Pavesi A S, Tallacchini M, Vendramini E A, Renda, Andrea, Renda, Andrea (ORCID:0000-0001-9669-9730), De Paoli M, Manfredi G, Pavesi A S, Tallacchini M, Vendramini E A, Renda, Andrea, and Renda, Andrea (ORCID:0000-0001-9669-9730)
- Abstract
The essay deals with the phenomenon of ‘new philanthropy’ from a juridical point of view, wondering if Italian civil law that rules the contract of donation is able to reach a fair balance between the interests of donors and those of donees. Some legal scholars reckon that there are too many limits to the act of donation, such as those arising from the constraint of a solemn form and above all those related to forced heirship (‘successione necessaria’), according to which an indefeasible portion of the estate passes to the deceased’s next-of-kin. On the contrary, the author argues the reasons why these limits aim, on the one hand, to make the donor aware of the seriousness of the choice of undergoing a pauperization, and, on the other, to fulfil the constitutional protection of the nuclear family. Moreover, although forced heirs can use a specific legal action (called ‘azione di riduzione’) that permits them to restore the reserved portion, donations can be abated only after the testamentary dispositions exceeding the disposable portion have been reduced.
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- 2017
6. La liberalità come fattore di sviluppo del diritto: un caso altomedievale
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Tallacchini, M., Vendramini, E.A., Manfredi, G., De Paoli, M., Pavesi, A., Isotton, Roberto, Isotton (ORCID:0000-0001-5810-760X), Tallacchini, M., Vendramini, E.A., Manfredi, G., De Paoli, M., Pavesi, A., Isotton, Roberto, and Isotton (ORCID:0000-0001-5810-760X)
- Abstract
Nell’ambito delle società altomedievali, il dono, l’atto di liberalità, non risponde completamente a logiche di gratuità, ma, come l’antropologia moderna insegna a proposito delle società “primitive”, si inserisce in un fitto reticolo di relazioni intersoggettive. Un esempio emblematico in tal senso può essere rappresentato dal fenomeno delle donationes pro anima, tipico della civiltà longobarda fra VII e VIII secolo, che si segnala per la natura ‘comunitaria’ dell’atto dispositivo, ma che, al tempo stesso, apre (o meglio: riapre) la strada a forme di successione volontaria che sembravano essere scomparse con la civilitas romana a vantaggio di regole improntate ad una dimensione super-individuale della vita associata., In the early medieval society, the gift, the donation, does not fully respond to the logic of gratuitousness, but, as modern anthropology teaches about the "primitive" societies, is part of a dense network of interpersonal relationships. An emblematic exemple in this sense can be represented by the case of the donationes pro anima, typical of Lombard civilization between VII and VIII century, which is notable for the 'Communal’ nature of this act, but which, at the same time, opens (or rather re-opens) the way to forms of voluntary succession that seemed to have disappeared with the Roman civilitas, for the benefit of rules inspired by a super-individual dimension of social life.
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- 2017
7. Premessa
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De Paoli, M, Manfredi G., Pavesi, A.S., Tallacchini, M., Vendramini, Chizzoniti, Antonio Giuseppe Maria, Chizzoniti Antonio Giuseppe Maria (ORCID:0000-0001-8894-9488), De Paoli, M, Manfredi G., Pavesi, A.S., Tallacchini, M., Vendramini, Chizzoniti, Antonio Giuseppe Maria, and Chizzoniti Antonio Giuseppe Maria (ORCID:0000-0001-8894-9488)
- Abstract
Introducento il volume si sofferma sulla distinzione tra filontrapia e carità nella dottrina sociale della Chiesa
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- 2017
8. Una proposta per prevenire il costo sociale delle espropriazioni immobiliari efficienti: le garanzie 'etiche' a scopo esdebitatorio.
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DE PAOLI M, MANFREDI G, PAVESI A S, TALLACCHINI M, VENDRAMINI E A, Barletta, Antonino, BARLETTA A (ORCID:0000-0001-5924-063X), DE PAOLI M, MANFREDI G, PAVESI A S, TALLACCHINI M, VENDRAMINI E A, Barletta, Antonino, and BARLETTA A (ORCID:0000-0001-5924-063X)
- Abstract
Vengono esaminate nuove possibili forme di garanzie volte a contrastare i principali problemi connessi all'obiettivo di rendere sempre più efficienti le l'espropriazioni in una prospettiva di c.d. "finanza etica".
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- 2017
9. Fondazioni d’impresa e Valore condiviso
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De Paoli, M., Manfredi, G., Pavesi, A.S., Tallacchini, M.,, Vendramini, E.A., Minciullo, Marco, marco minciullo (ORCID:0000-0002-6181-3860), De Paoli, M., Manfredi, G., Pavesi, A.S., Tallacchini, M.,, Vendramini, E.A., Minciullo, Marco, and marco minciullo (ORCID:0000-0002-6181-3860)
- Abstract
This study aims to reconsider the phenomenon of Corporate Foundations under the shared value perspective, highlighting the ability of these organizations to respond to requests of multiple categories of stakeholders. Through the analysis of CFs peculiarities the study will underline the characteristics that are suitable for taking into consideration the potential role of CFs, by means of creating value for both society and firm. Thus, this paper aspires to contribute to the growth of knowledge in the field of Corporate Foundations by adopting an integrated perspective, and by providing suggestions for stimulating new directions for further inquiry.
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- 2017
10. Complessità del ‘dono’ e orizzonte comunitario: una lettura filosofico-giuridica
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De Paoli, M, Manfredi, G, Pavesi, SA, Tallacchini, M, Vendramini, EA, Bombelli, Giovanni, G. Bombelli (ORCID:0000-0003-0486-9902), De Paoli, M, Manfredi, G, Pavesi, SA, Tallacchini, M, Vendramini, EA, Bombelli, Giovanni, and G. Bombelli (ORCID:0000-0003-0486-9902)
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This essay addresses from a philosophical-legal perspective the concept of ‘gift’ and its close relation with the communitarian dimension. Starting from the theory elaborated by René Girard, in particular his idea of ‘scapegoat’, it is possible to highlight three dimensions of the gift: the gift as a social fundament, the gift as a violence dimension and the gift as a politicalinstitutional bond. This theoretical model allows to compare the gift and the communitarian dimension, paradigmatically the Greek experience and the early Christian communities, and to clarify the dialectical relation between the nexus gift-community and law (also with regard to New Philanthropy). In spite of the current opposition between donative agency and strategicinstrumental reason, the relation gift-law should be understood in a more complex manner. Having an immediate and direct social-institutional projection, gift intrinsically ‘creates law’: more widely it implies the implementation of a political-legal bond.
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- 2017
11. Una Filantropia Nuova. Economia, diritto e filosofia per una societa' digitale collaborativa
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Tallacchini M. (ORCID:0000-0003-3730-3673), Vendramini E. (ORCID:0000-0001-9386-9626), Manfredi, Giuseppe, Tallacchini, M., Vendramini, E., Pavesi, A., De Paoli, M., Tallacchini M. (ORCID:0000-0003-3730-3673), Vendramini E. (ORCID:0000-0001-9386-9626), Manfredi, Giuseppe, Tallacchini, M., Vendramini, E., Pavesi, A., and De Paoli, M.
- Abstract
Nelle società contemporanee nuovi fenomeni culturali di condivisione, collaborazione e solidarietà si stanno consolidando e moltiplicando con un ritmo inarrestabile, e stanno radicalmente ridefinendo i rapporti tra individui e collettività. Il ruolo delle tecnologie digitali e del loro diffuso e capillare potere di connettività è centrale e cruciale nel determinare nuovi bisogni e aspirazioni antropologici, etici, sociali e democratici, ma è anche all’origine di molteplici forme di innovazione economica. Accanto a inesplorate – perché in precedenza non fattibili – possibilità di raggiungere ‘altri’ lontani e di intervenire in ‘cause sociali’ distanti attraverso la ‘prossimità’ della realtà virtuale, tutte le dimensioni del lasciare, consegnare e distribuire ad altri beni, appartenenze e capacità—da quelle più personali ed esistenziali fino a quelle collettive e pubbliche— stanno evolvendo rapidamente insieme. L’espressione ‘nuova filantropia’ (New Philanthropy) è nata all’interno della generazione di imprenditori del dot-com, l’industria dell’informatica e del digitale, come una filantropia diversa e ‘strategica’, interessata a, e capace di, produrre e misurare gli impatti del ben-fare. Più in generale, però, la locuzione si riferisce al vasto movimento teorico e sociale per ripensare il non-profit, la liberalità, l’impegno solidale e collaborativo.
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- 2017
12. The Rarita-Schwinger Particles Under de Influence of Strong Magnetic Fields
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de Paoli, M. G., Menezes, D. P., Castro, L. B., Barros Jr, C. C., de Paoli, M. G., Menezes, D. P., Castro, L. B., and Barros Jr, C. C.
- Abstract
In this work, we calculate the solutions of the Rarita-Schwinger equation with the inclusion of the eletromagnetic interaction. Our gauge and coupling prescription choices lead to Dirac-type solutions. One of the consequences of our results are the Landau level occupation of particles, quite different from the usual spin 1/2 particle system occupation numbers., Comment: 12 pages
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- 2012
- Full Text
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13. The Rarita-Schwinger Particles Under de Influence of Strong Magnetic Fields
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de Paoli, M. G., Menezes, D. P., Castro, L. B., Barros Jr, C. C., de Paoli, M. G., Menezes, D. P., Castro, L. B., and Barros Jr, C. C.
- Abstract
In this work, we calculate the solutions of the Rarita-Schwinger equation with the inclusion of the eletromagnetic interaction. Our gauge and coupling prescription choices lead to Dirac-type solutions. One of the consequences of our results are the Landau level occupation of particles, quite different from the usual spin 1/2 particle system occupation numbers., Comment: 12 pages
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- 2012
- Full Text
- View/download PDF
14. The importance of the mixed phase in hybrid stars built with the Nambu-Jona-Lasinio model
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Paoli, M. G., Menezes, D. P., Paoli, M. G., and Menezes, D. P.
- Abstract
We investigate the structure of hybrid stars based on two different constructions: one is based on the Gibbs condition for phase coexistence and considers the existence of a mixed phase (MP), and the other is based on the Maxwell construction and no mixed phase is obtained. The hadron phase is described by the non-linear Walecka model (NLW) and the quark phase by the Nambu-Jona-Lasinio model (NJL). We conclude that the masses and radii obtained are model dependent but not significantly different for both constructions., Comment: 8 pages, 7 figures, 3 tables
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- 2010
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15. The molecular heterogeneity of hemocyanin: structural and functional properties of the 4x6-meric protein of Crustacea.
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Paoli, M., Giomi, Folco, Hellmann, N., Jaenicke, E., Decker, H., Di Muro, P., Beltramini, M., Paoli, M., Giomi, Folco, Hellmann, N., Jaenicke, E., Decker, H., Di Muro, P., and Beltramini, M.
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- 2007
16. The molecular heterogeneity of hemocyanin: structural and functional properties of the 4x6-meric protein of Crustacea.
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Paoli, M., Giomi, Folco, Hellmann, N., Jaenicke, E., Decker, H., Di Muro, P., Beltramini, M., Paoli, M., Giomi, Folco, Hellmann, N., Jaenicke, E., Decker, H., Di Muro, P., and Beltramini, M.
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- 2007
17. A comparative assessment of heavy metal accumulation in soft parts and byssus of mussels from subarctic, temperate, subtropical and tropical marine environments
- Author
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Szefer, P., Fowler, S.W., Ikuta, K., Paez Osuna, F., Ali, A.A., Kim, B-S., Fernandes, H.M., Belzunce, M.J., Guterstam, B., Kunzendorf, H., Wolowicz, M., Hummel, H., Deslous-Paoli, M., Szefer, P., Fowler, S.W., Ikuta, K., Paez Osuna, F., Ali, A.A., Kim, B-S., Fernandes, H.M., Belzunce, M.J., Guterstam, B., Kunzendorf, H., Wolowicz, M., Hummel, H., and Deslous-Paoli, M.
- Abstract
Existing data on metal concentrations in mussels from subarctic, temperate, subtropical and tropical waters were analyzed using multivariate statistics in order to assess regional variations in metal contamination. Potential errors were reduced by only analyzing data from surveys that employed the same protocols, analytical methodologies and analysts. Factor analysis demonstrated that mussels inhabiting extremely contaminated areas (e.g. from Japanese and Swedish metallurgy sources) could be separated from mussels from other contaminated areas, and that metals such as Cd, Pb, Cu and Zn could be used to identify heavily contaminated samples while Co, Fe, Cr and Ni concentrations were good markers for exposure to inputs from different industrial sources. Furthermore byssus, like soft tissue, selectively and sensitively reflects variations of certain metal concentrations in ambient waters and thus serves as a reliable biomonitor for these contaminants in a variety of coastal and estuarine areas. Byssus of mytilids, like soft tissues can be used as efficient biomonitor for heavy metals in the marine environment. [KEYWORDS: mussel ; Trace metals ; Soft tissue ; Byssus ; Temperate ; Subtropical and tropical marine regions], Existing data on metal concentrations in mussels from subarctic, temperate, subtropical and tropical waters were analyzed using multivariate statistics in order to assess regional variations in metal contamination. Potential errors were reduced by only analyzing data from surveys that employed the same protocols, analytical methodologies and analysts. Factor analysis demonstrated that mussels inhabiting extremely contaminated areas (e.g. from Japanese and Swedish metallurgy sources) could be separated from mussels from other contaminated areas, and that metals such as Cd, Pb, Cu and Zn could be used to identify heavily contaminated samples while Co, Fe, Cr and Ni concentrations were good markers for exposure to inputs from different industrial sources. Furthermore byssus, like soft tissue, selectively and sensitively reflects variations of certain metal concentrations in ambient waters and thus serves as a reliable biomonitor for these contaminants in a variety of coastal and estuarine areas. Byssus of mytilids, like soft tissues can be used as efficient biomonitor for heavy metals in the marine environment. [KEYWORDS: mussel ; Trace metals ; Soft tissue ; Byssus ; Temperate ; Subtropical and tropical marine regions]
- Published
- 2006
18. A comparative assessment of heavy metal accumulation in soft parts and byssus of mussels from subarctic, temperate, subtropical and tropical marine environments
- Author
-
Szefer, P., Fowler, S.W., Ikuta, K., Paez Osuna, F., Ali, A.A., Kim, B-S., Fernandes, H.M., Belzunce, M.J., Guterstam, B., Kunzendorf, H., Wolowicz, M., Hummel, H., Deslous-Paoli, M., Szefer, P., Fowler, S.W., Ikuta, K., Paez Osuna, F., Ali, A.A., Kim, B-S., Fernandes, H.M., Belzunce, M.J., Guterstam, B., Kunzendorf, H., Wolowicz, M., Hummel, H., and Deslous-Paoli, M.
- Abstract
Existing data on metal concentrations in mussels from subarctic, temperate, subtropical and tropical waters were analyzed using multivariate statistics in order to assess regional variations in metal contamination. Potential errors were reduced by only analyzing data from surveys that employed the same protocols, analytical methodologies and analysts. Factor analysis demonstrated that mussels inhabiting extremely contaminated areas (e.g. from Japanese and Swedish metallurgy sources) could be separated from mussels from other contaminated areas, and that metals such as Cd, Pb, Cu and Zn could be used to identify heavily contaminated samples while Co, Fe, Cr and Ni concentrations were good markers for exposure to inputs from different industrial sources. Furthermore byssus, like soft tissue, selectively and sensitively reflects variations of certain metal concentrations in ambient waters and thus serves as a reliable biomonitor for these contaminants in a variety of coastal and estuarine areas. Byssus of mytilids, like soft tissues can be used as efficient biomonitor for heavy metals in the marine environment. [KEYWORDS: mussel ; Trace metals ; Soft tissue ; Byssus ; Temperate ; Subtropical and tropical marine regions], Existing data on metal concentrations in mussels from subarctic, temperate, subtropical and tropical waters were analyzed using multivariate statistics in order to assess regional variations in metal contamination. Potential errors were reduced by only analyzing data from surveys that employed the same protocols, analytical methodologies and analysts. Factor analysis demonstrated that mussels inhabiting extremely contaminated areas (e.g. from Japanese and Swedish metallurgy sources) could be separated from mussels from other contaminated areas, and that metals such as Cd, Pb, Cu and Zn could be used to identify heavily contaminated samples while Co, Fe, Cr and Ni concentrations were good markers for exposure to inputs from different industrial sources. Furthermore byssus, like soft tissue, selectively and sensitively reflects variations of certain metal concentrations in ambient waters and thus serves as a reliable biomonitor for these contaminants in a variety of coastal and estuarine areas. Byssus of mytilids, like soft tissues can be used as efficient biomonitor for heavy metals in the marine environment. [KEYWORDS: mussel ; Trace metals ; Soft tissue ; Byssus ; Temperate ; Subtropical and tropical marine regions]
- Published
- 2006
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