12 results on '"O'Donnell, James S"'
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2. O-glycan determinants regulate VWF trafficking to Weibel-Palade bodies
- Author
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Karampini, Ellie, Doherty, Dearbhla, Bürgisser, Petra E., Garre, Massimiliano, Schoen, Ingmar, Elliott, Stephanie, Bierings, Ruben, O’Donnell, James S., Karampini, Ellie, Doherty, Dearbhla, Bürgisser, Petra E., Garre, Massimiliano, Schoen, Ingmar, Elliott, Stephanie, Bierings, Ruben, and O’Donnell, James S.
- Abstract
von Willebrand factor (VWF) undergoes complex posttranslational modification within endothelial cells (ECs) before secretion. This includes significant N- and O-linked glycosylation. Previous studies have demonstrated that changes in N-linked glycan structures significantly influence VWF biosynthesis. In contrast, although abnormalities in VWF O-linked glycans (OLGs) have been associated with enhanced VWF clearance, their effect on VWF biosynthesis remains poorly explored. Herein, we report a novel role for OLG determinants in regulating VWF biosynthesis and trafficking within ECs. We demonstrate that alterations in OLGs (notably reduced terminal sialylation) lead to activation of the A1 domain of VWF within EC. In the presence of altered OLG, VWF multimerization is reduced and Weibel-Palade body (WPB) formation significantly impaired. Consistently, the amount of VWF secreted from WPB after EC activation was significantly reduced in the context of O-glycosylation inhibition. Finally, altered OLG on VWF not only reduced the amount of VWF secreted after EC activation but also affected its hemostatic efficacy. Notably, VWF secreted after WPB exocytosis consisted predominantly of low molecular weight multimers, and the length of tethered VWF string formation on the surface of activated ECs was significantly reduced. In conclusion, our data therefore support the hypothesis that alterations in O-glycosylation pathways directly affect VWF trafficking within human EC. These findings are interesting given that previous studies have reported altered OLG on plasma VWF (notably increased T-antigen expression) in patients with von Willebrand disease.
- Published
- 2024
3. Musculoskeletal ultrasound in hemophilia: Results and recommendations from a global survey and consensus meeting.
- Author
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UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service d'hématologie, Bakeer, Nihal, Dover, Saunya, Babyn, Paul, Feldman, Brian M, von Drygalski, Annette, Doria, Andrea S, Ignas, Danial M, Abad, Audrey, Bailey, Cindy, Beggs, Ian, Chang, Eric Y, Dunn, Amy, Funk, Sharon, Gibikote, Sridhar, Goddard, Nicholas, Hilliard, Pamela, Keshava, Shyamkumar N, Kruse-Jarres, Rebecca, Li, Yingjia, Lobet, Sébastien, Manco-Johnson, Marilyn, Martinoli, Carlo, O'Donnell, James S, Papakonstantinou, Olympia, Pergantou, Helen, Poonnoose, Pradeep, Querol, Felipe, Srivastava, Alok, Steiner, Bruno, Strike, Karen, Timmer, Merel, Tyrrell, Pascal N, Vidarsson, Logi, Blanchette, Victor S, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service d'hématologie, Bakeer, Nihal, Dover, Saunya, Babyn, Paul, Feldman, Brian M, von Drygalski, Annette, Doria, Andrea S, Ignas, Danial M, Abad, Audrey, Bailey, Cindy, Beggs, Ian, Chang, Eric Y, Dunn, Amy, Funk, Sharon, Gibikote, Sridhar, Goddard, Nicholas, Hilliard, Pamela, Keshava, Shyamkumar N, Kruse-Jarres, Rebecca, Li, Yingjia, Lobet, Sébastien, Manco-Johnson, Marilyn, Martinoli, Carlo, O'Donnell, James S, Papakonstantinou, Olympia, Pergantou, Helen, Poonnoose, Pradeep, Querol, Felipe, Srivastava, Alok, Steiner, Bruno, Strike, Karen, Timmer, Merel, Tyrrell, Pascal N, Vidarsson, Logi, and Blanchette, Victor S
- Abstract
For persons with hemophilia, optimization of joint outcomes is an important unmet need. The aim of this initiative was to determine use of ultrasound in evaluating arthropathy in persons with hemophilia, and to move toward consensus among hemophilia care providers regarding the preferred ultrasound protocols for global adaptation. A global survey of hemophilia treatment centers was conducted that focused on understanding how and why ultrasound was being used and endeavored to move toward consensus definitions of both point-of-care musculoskeletal ultrasound (POC-MSKUS) and full diagnostic ultrasound, terminology to describe structures being assessed by ultrasound, and how these assessments should be interpreted. Next, an in-person meeting of an international group of hemophilia health care professionals and patient representatives was held, with the objective of achieving consensus regarding the acquisition and interpretation of POC-MSKUS and full diagnostic ultrasound for use in the assessment of musculoskeletal (MSK) pathologies in persons with hemophilia. The recommendations were that clear definitions of the types of ultrasound examinations should be adopted and that a standardized ultrasound scoring/measurement system should be developed, tested, and implemented. The scoring/measurement system should be tiered to allow for a range of complexity yet maintain the ability for comparison across levels. Ultrasound is an evolving technology increasingly used for the assessment of MSK outcomes in persons with hemophilia. As adoption increases globally for clinical care and research, it will become increasingly important to establish clear guidelines for image acquisition, interpretation, and reporting to ensure accuracy, consistency, and comparability across groups.
- Published
- 2021
4. Illustrated State-of-the-Art Capsules of the ISTH 2021 Congress
- Author
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Krishnaswamy, Sriram, Ageno, Walter, Arabi, Yaseen, Barbui, Tiziano, Cannegieter, Suzanne, Carrier, Marc, Cleuren, Audrey C., Collins, Peter, Panicot-Dubois, Laurence, Freedman, Jane E., Freson, Kathleen, Hogg, Philip, James, Andra H., Kretz, Colin A., Lavin, Michelle, Leebeek, Frank W.G., Li, Weikai, Maas, Coen, Machlus, Kellie, Makris, Michael, Martinelli, Ida, Medved, Leonid, Neerman-Arbez, Marguerite, O’Donnell, James S., O'Sullivan, Jamie, Rajpurkar, Madhvi, Schroeder, Verena, Spiegel, Paul Clinton, Stanworth, Simon J., Green, Laura, Undas, Anetta, Krishnaswamy, Sriram, Ageno, Walter, Arabi, Yaseen, Barbui, Tiziano, Cannegieter, Suzanne, Carrier, Marc, Cleuren, Audrey C., Collins, Peter, Panicot-Dubois, Laurence, Freedman, Jane E., Freson, Kathleen, Hogg, Philip, James, Andra H., Kretz, Colin A., Lavin, Michelle, Leebeek, Frank W.G., Li, Weikai, Maas, Coen, Machlus, Kellie, Makris, Michael, Martinelli, Ida, Medved, Leonid, Neerman-Arbez, Marguerite, O’Donnell, James S., O'Sullivan, Jamie, Rajpurkar, Madhvi, Schroeder, Verena, Spiegel, Paul Clinton, Stanworth, Simon J., Green, Laura, and Undas, Anetta
- Abstract
This year's Congress of the International Society of Thrombosis and Haemostasis (ISTH) was hosted virtually from Philadelphia July 17–21, 2021. The conference, now held annually, highlighted cutting-edge advances in basic, population and clinical sciences of relevance to the Society. Despite being held virtually, the 2021 congress was of the same scope and quality as an annual meeting held in person. An added feature of the program is that talks streamed at the designated times will then be available on-line for asynchronous viewing. The program included 77 State of the Art (SOA) talks, thematically grouped in 28 sessions, given by internationally recognized leaders in the field. The SOA speakers were invited to prepare brief illustrated reviews of their talks that were peer reviewed and are included in this article. The topics, across the main scientific themes of the congress, include Arterial Thromboembolism, Coagulation and Natural Anticoagulants, COVID-19 and Coagulation, Diagnostics and Omics, Fibrinogen, Fibrinolysis and Proteolysis, Hemophilia and Rare Bleeding Disorders, Hemostasis in Cancer, Inflammation and Immunity, Pediatrics, Platelet Disorders, von Willebrand Disease and Thrombotic Angiopathies, Platelets and Megakaryocytes, Vascular Biology, Venous Thromboembolism and Women's Health. These illustrated capsules highlight the major scientific advances with potential to impact clinical practice. Readers are invited to take advantage of the excellent educational resource provided by these illustrated capsules. They are also encouraged to use the image in social media to draw attention to the high quality and impact of the science presented at the congress.
- Published
- 2021
5. Illustrated State-of-the-Art Capsules of the ISTH 2021 Congress
- Author
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CDL Staf Research, Circulatory Health, Krishnaswamy, Sriram, Ageno, Walter, Arabi, Yaseen, Barbui, Tiziano, Cannegieter, Suzanne, Carrier, Marc, Cleuren, Audrey C, Collins, Peter, Panicot-Dubois, Laurence, Freedman, Jane E, Freson, Kathleen, Hogg, Philip, James, Andra H, Kretz, Colin A, Lavin, Michelle, Leebeek, Frank W G, Li, Weikai, Maas, Coen, Machlus, Kellie, Makris, Michael, Martinelli, Ida, Medved, Leonid, Neerman-Arbez, Marguerite, O'Donnell, James S, O'Sullivan, Jamie, Rajpurkar, Madhvi, Schroeder, Verena, Spiegel, Paul Clinton, Stanworth, Simon J, Green, Laura, Undas, Anetta, CDL Staf Research, Circulatory Health, Krishnaswamy, Sriram, Ageno, Walter, Arabi, Yaseen, Barbui, Tiziano, Cannegieter, Suzanne, Carrier, Marc, Cleuren, Audrey C, Collins, Peter, Panicot-Dubois, Laurence, Freedman, Jane E, Freson, Kathleen, Hogg, Philip, James, Andra H, Kretz, Colin A, Lavin, Michelle, Leebeek, Frank W G, Li, Weikai, Maas, Coen, Machlus, Kellie, Makris, Michael, Martinelli, Ida, Medved, Leonid, Neerman-Arbez, Marguerite, O'Donnell, James S, O'Sullivan, Jamie, Rajpurkar, Madhvi, Schroeder, Verena, Spiegel, Paul Clinton, Stanworth, Simon J, Green, Laura, and Undas, Anetta
- Published
- 2021
6. Musculoskeletal ultrasound in hemophilia: Results and recommendations from a global survey and consensus meeting
- Author
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Child Health, Poli Van Creveldkliniek Medisch, Circulatory Health, Bakeer, Nihal, Dover, Saunya, Babyn, Paul, Feldman, Brian M, von Drygalski, Annette, Doria, Andrea S, Ignas, Danial M, Abad, Audrey, Bailey, Cindy, Beggs, Ian, Chang, Eric Y, Dunn, Amy, Funk, Sharon, Gibikote, Sridhar, Goddard, Nicholas, Hilliard, Pamela, Keshava, Shyamkumar N, Kruse-Jarres, Rebecca, Li, Yingjia, Lobet, Sébastien, Manco-Johnson, Marilyn, Martinoli, Carlo, O'Donnell, James S, Papakonstantinou, Olympia, Pergantou, Helen, Poonnoose, Pradeep, Querol, Felipe, Srivastava, Alok, Steiner, Bruno, Strike, Karen, Timmer, Merel, Tyrrell, Pascal N, Vidarsson, Logi, Blanchette, Victor S, Child Health, Poli Van Creveldkliniek Medisch, Circulatory Health, Bakeer, Nihal, Dover, Saunya, Babyn, Paul, Feldman, Brian M, von Drygalski, Annette, Doria, Andrea S, Ignas, Danial M, Abad, Audrey, Bailey, Cindy, Beggs, Ian, Chang, Eric Y, Dunn, Amy, Funk, Sharon, Gibikote, Sridhar, Goddard, Nicholas, Hilliard, Pamela, Keshava, Shyamkumar N, Kruse-Jarres, Rebecca, Li, Yingjia, Lobet, Sébastien, Manco-Johnson, Marilyn, Martinoli, Carlo, O'Donnell, James S, Papakonstantinou, Olympia, Pergantou, Helen, Poonnoose, Pradeep, Querol, Felipe, Srivastava, Alok, Steiner, Bruno, Strike, Karen, Timmer, Merel, Tyrrell, Pascal N, Vidarsson, Logi, and Blanchette, Victor S
- Published
- 2021
7. Musculoskeletal ultrasound in hemophilia: Results and recommendations from a global survey and consensus meeting
- Author
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UCL - (SLuc) Service d'hématologie, Bakeer, Nihal, Dover, Saunya, Babyn, Paul, Feldman, Brian M., Drygalski, Annette, Doria, Andrea S., Ignas, Danial M., Abad, Audrey, Bailey, Cindy, Beggs, Ian, Chang, Eric Y., Dunn, Amy, Funk, Sharon, Gibikote, Sridhar, Goddard, Nicholas, Hilliard, Pamela, Keshava, Shyamkumar N., Kruse‐Jarres, Rebecca, Li, Yingjia, Lobet, Sébastien, Manco‐Johnson, Marilyn, Martinoli, Carlo, O’Donnell, James S., Papakonstantinou, Olympia, Pergantou, Helen, Poonnoose, Pradeep, Querol, Felipe, Srivastava, Alok, Steiner, Bruno, Strike, Karen, Timmer, Merel, Tyrrell, Pascal N., Vidarsson, Logi, Blanchette, Victor S., UCL - (SLuc) Service d'hématologie, Bakeer, Nihal, Dover, Saunya, Babyn, Paul, Feldman, Brian M., Drygalski, Annette, Doria, Andrea S., Ignas, Danial M., Abad, Audrey, Bailey, Cindy, Beggs, Ian, Chang, Eric Y., Dunn, Amy, Funk, Sharon, Gibikote, Sridhar, Goddard, Nicholas, Hilliard, Pamela, Keshava, Shyamkumar N., Kruse‐Jarres, Rebecca, Li, Yingjia, Lobet, Sébastien, Manco‐Johnson, Marilyn, Martinoli, Carlo, O’Donnell, James S., Papakonstantinou, Olympia, Pergantou, Helen, Poonnoose, Pradeep, Querol, Felipe, Srivastava, Alok, Steiner, Bruno, Strike, Karen, Timmer, Merel, Tyrrell, Pascal N., Vidarsson, Logi, and Blanchette, Victor S.
- Published
- 2020
8. Illustrated State-of-the-Art Capsules of the ISTH 2019 Congress in Melbourne, Australia : Plasminogen in wound healing
- Author
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Andrews, Robert K., Wolberg, Alisa, Lip, Gregory Y. H., Eikelboom, John, De Meyer, Simon F., Mast, Alan, Flick, Matthew, Urano, Tetsumei, Ny, Tor, Cutler, Daniel, Ju, Lining A., Zhu, Cheng, Randi, Anna M., O'Donnell, James S., O'Brien, Sarah H., Fijnvandraat, Karin, Shima, Midori, Nathwani, Amit, Luyendyk, Jim, Vanhoorelbeke, Karen, Barco, Stefano, Chuansumrit, Ampaiwan, Stanworth, Simon J., Curry, Nicola, Del Rio, J. Mauricio, Battinelli, Elisabeth M., Bos, Mettine H. A., Reinhardt, Christoph, Peter, Karlheinz, Gomez, Keith, Danese, Elisa, Rak, Janusz, Flaumenhaft, Robert, Di Paola, Jorge, Nilsson, Susie, Severin, Sonia, Eto, Koji, Hitchcock, Ian S., Ni, Heyu, Despotovic, Jenny, Boilard, Eric, Rondina, Matthew, Mangin, Pierre, Hamilton, Justin R., Suzuki-Inoue, Katsue, Tsukiji, Nagaharu, Conway, Edward M., Maas, Coen, Emsley, Jonas, Jenne, Craig N., Fuchs, Tobias A., Weitz, Jeffrey, Johnsen, Jill M., Rauova, Lubica, Spyropoulos, Alex, Goto, Shinya, Verhamme, Peter, Miranda, Sebastien, Rodger, Marc, Ni Ainle, Fionnuala, Schreiber, Karen, Thomas, Moumneh, Le Gal, Gregoire, Zentner, Dominica, McLintock, Claire, Magnusson, Maria, Andrews, Robert K., Wolberg, Alisa, Lip, Gregory Y. H., Eikelboom, John, De Meyer, Simon F., Mast, Alan, Flick, Matthew, Urano, Tetsumei, Ny, Tor, Cutler, Daniel, Ju, Lining A., Zhu, Cheng, Randi, Anna M., O'Donnell, James S., O'Brien, Sarah H., Fijnvandraat, Karin, Shima, Midori, Nathwani, Amit, Luyendyk, Jim, Vanhoorelbeke, Karen, Barco, Stefano, Chuansumrit, Ampaiwan, Stanworth, Simon J., Curry, Nicola, Del Rio, J. Mauricio, Battinelli, Elisabeth M., Bos, Mettine H. A., Reinhardt, Christoph, Peter, Karlheinz, Gomez, Keith, Danese, Elisa, Rak, Janusz, Flaumenhaft, Robert, Di Paola, Jorge, Nilsson, Susie, Severin, Sonia, Eto, Koji, Hitchcock, Ian S., Ni, Heyu, Despotovic, Jenny, Boilard, Eric, Rondina, Matthew, Mangin, Pierre, Hamilton, Justin R., Suzuki-Inoue, Katsue, Tsukiji, Nagaharu, Conway, Edward M., Maas, Coen, Emsley, Jonas, Jenne, Craig N., Fuchs, Tobias A., Weitz, Jeffrey, Johnsen, Jill M., Rauova, Lubica, Spyropoulos, Alex, Goto, Shinya, Verhamme, Peter, Miranda, Sebastien, Rodger, Marc, Ni Ainle, Fionnuala, Schreiber, Karen, Thomas, Moumneh, Le Gal, Gregoire, Zentner, Dominica, McLintock, Claire, and Magnusson, Maria
- Abstract
The 27th Congress of the International Society of Thrombosis and Haemostasis (ISTH) is an international conference held July 6-10, 2019, in Melbourne, the capital of the state of Victoria, Australia. The ISTH congress has previously been held every other year, with the Scientific and Standardization Committee (SSC) meeting held annually, until 2019 when it became one combined annual meeting of the ISTH and SSC. The conference covers clinical and basic aspects of hemostasis and thrombosis, and this year includes 5 Plenary lectures and >50 State of Art (SOA) lectures, presented by internationally recognized speakers, as well as numerous oral session and poster presentations selected from submitted abstracts, including many early career and reach the world support recipients. This SOA review article in RPTH contains concise Illustrated Review Articles or 'Capsules' consisting of short text, three references and a figure, with topics including stroke, cancer-associated thrombosis, hemophilia, coagulation, the interface between infection and inflammation, and in the experimental and discovery areas, megakaryocyte biology and platelet production, structure-function of key receptors and coagulation factors, and emerging new roles for thrombotic/hemostatic factors. Together, these articles highlight novel findings which will advance knowledge and with the potential to change clinical practice and improve outcomes. It is hoped that conference attendees and followers will enjoy utilizing the images for ongoing education and during the conference for live tweeting during sessions, to assist in the broadcasting and promotion of the science to those unable to attend, or who have chosen to attend a concurrent session. Use #IllustratedReview and #ISTH2019 on social media.
- Published
- 2019
- Full Text
- View/download PDF
9. Illustrated State-of-the-Art Capsules of the ISTH 2019 Congress in Melbourne, Australia : Plasminogen in wound healing
- Author
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Andrews, Robert K., Wolberg, Alisa, Lip, Gregory Y. H., Eikelboom, John, De Meyer, Simon F., Mast, Alan, Flick, Matthew, Urano, Tetsumei, Ny, Tor, Cutler, Daniel, Ju, Lining A., Zhu, Cheng, Randi, Anna M., O'Donnell, James S., O'Brien, Sarah H., Fijnvandraat, Karin, Shima, Midori, Nathwani, Amit, Luyendyk, Jim, Vanhoorelbeke, Karen, Barco, Stefano, Chuansumrit, Ampaiwan, Stanworth, Simon J., Curry, Nicola, Del Rio, J. Mauricio, Battinelli, Elisabeth M., Bos, Mettine H. A., Reinhardt, Christoph, Peter, Karlheinz, Gomez, Keith, Danese, Elisa, Rak, Janusz, Flaumenhaft, Robert, Di Paola, Jorge, Nilsson, Susie, Severin, Sonia, Eto, Koji, Hitchcock, Ian S., Ni, Heyu, Despotovic, Jenny, Boilard, Eric, Rondina, Matthew, Mangin, Pierre, Hamilton, Justin R., Suzuki-Inoue, Katsue, Tsukiji, Nagaharu, Conway, Edward M., Maas, Coen, Emsley, Jonas, Jenne, Craig N., Fuchs, Tobias A., Weitz, Jeffrey, Johnsen, Jill M., Rauova, Lubica, Spyropoulos, Alex, Goto, Shinya, Verhamme, Peter, Miranda, Sebastien, Rodger, Marc, Ni Ainle, Fionnuala, Schreiber, Karen, Thomas, Moumneh, Le Gal, Gregoire, Zentner, Dominica, McLintock, Claire, Magnusson, Maria, Andrews, Robert K., Wolberg, Alisa, Lip, Gregory Y. H., Eikelboom, John, De Meyer, Simon F., Mast, Alan, Flick, Matthew, Urano, Tetsumei, Ny, Tor, Cutler, Daniel, Ju, Lining A., Zhu, Cheng, Randi, Anna M., O'Donnell, James S., O'Brien, Sarah H., Fijnvandraat, Karin, Shima, Midori, Nathwani, Amit, Luyendyk, Jim, Vanhoorelbeke, Karen, Barco, Stefano, Chuansumrit, Ampaiwan, Stanworth, Simon J., Curry, Nicola, Del Rio, J. Mauricio, Battinelli, Elisabeth M., Bos, Mettine H. A., Reinhardt, Christoph, Peter, Karlheinz, Gomez, Keith, Danese, Elisa, Rak, Janusz, Flaumenhaft, Robert, Di Paola, Jorge, Nilsson, Susie, Severin, Sonia, Eto, Koji, Hitchcock, Ian S., Ni, Heyu, Despotovic, Jenny, Boilard, Eric, Rondina, Matthew, Mangin, Pierre, Hamilton, Justin R., Suzuki-Inoue, Katsue, Tsukiji, Nagaharu, Conway, Edward M., Maas, Coen, Emsley, Jonas, Jenne, Craig N., Fuchs, Tobias A., Weitz, Jeffrey, Johnsen, Jill M., Rauova, Lubica, Spyropoulos, Alex, Goto, Shinya, Verhamme, Peter, Miranda, Sebastien, Rodger, Marc, Ni Ainle, Fionnuala, Schreiber, Karen, Thomas, Moumneh, Le Gal, Gregoire, Zentner, Dominica, McLintock, Claire, and Magnusson, Maria
- Abstract
The 27th Congress of the International Society of Thrombosis and Haemostasis (ISTH) is an international conference held July 6-10, 2019, in Melbourne, the capital of the state of Victoria, Australia. The ISTH congress has previously been held every other year, with the Scientific and Standardization Committee (SSC) meeting held annually, until 2019 when it became one combined annual meeting of the ISTH and SSC. The conference covers clinical and basic aspects of hemostasis and thrombosis, and this year includes 5 Plenary lectures and >50 State of Art (SOA) lectures, presented by internationally recognized speakers, as well as numerous oral session and poster presentations selected from submitted abstracts, including many early career and reach the world support recipients. This SOA review article in RPTH contains concise Illustrated Review Articles or 'Capsules' consisting of short text, three references and a figure, with topics including stroke, cancer-associated thrombosis, hemophilia, coagulation, the interface between infection and inflammation, and in the experimental and discovery areas, megakaryocyte biology and platelet production, structure-function of key receptors and coagulation factors, and emerging new roles for thrombotic/hemostatic factors. Together, these articles highlight novel findings which will advance knowledge and with the potential to change clinical practice and improve outcomes. It is hoped that conference attendees and followers will enjoy utilizing the images for ongoing education and during the conference for live tweeting during sessions, to assist in the broadcasting and promotion of the science to those unable to attend, or who have chosen to attend a concurrent session. Use #IllustratedReview and #ISTH2019 on social media.
- Published
- 2019
- Full Text
- View/download PDF
10. Illustrated State-of-the-Art Capsules of the ISTH 2019 Congress in Melbourne, Australia : Plasminogen in wound healing
- Author
-
Andrews, Robert K., Wolberg, Alisa, Lip, Gregory Y. H., Eikelboom, John, De Meyer, Simon F., Mast, Alan, Flick, Matthew, Urano, Tetsumei, Ny, Tor, Cutler, Daniel, Ju, Lining A., Zhu, Cheng, Randi, Anna M., O'Donnell, James S., O'Brien, Sarah H., Fijnvandraat, Karin, Shima, Midori, Nathwani, Amit, Luyendyk, Jim, Vanhoorelbeke, Karen, Barco, Stefano, Chuansumrit, Ampaiwan, Stanworth, Simon J., Curry, Nicola, Del Rio, J. Mauricio, Battinelli, Elisabeth M., Bos, Mettine H. A., Reinhardt, Christoph, Peter, Karlheinz, Gomez, Keith, Danese, Elisa, Rak, Janusz, Flaumenhaft, Robert, Di Paola, Jorge, Nilsson, Susie, Severin, Sonia, Eto, Koji, Hitchcock, Ian S., Ni, Heyu, Despotovic, Jenny, Boilard, Eric, Rondina, Matthew, Mangin, Pierre, Hamilton, Justin R., Suzuki-Inoue, Katsue, Tsukiji, Nagaharu, Conway, Edward M., Maas, Coen, Emsley, Jonas, Jenne, Craig N., Fuchs, Tobias A., Weitz, Jeffrey, Johnsen, Jill M., Rauova, Lubica, Spyropoulos, Alex, Goto, Shinya, Verhamme, Peter, Miranda, Sebastien, Rodger, Marc, Ni Ainle, Fionnuala, Schreiber, Karen, Thomas, Moumneh, Le Gal, Gregoire, Zentner, Dominica, McLintock, Claire, Magnusson, Maria, Andrews, Robert K., Wolberg, Alisa, Lip, Gregory Y. H., Eikelboom, John, De Meyer, Simon F., Mast, Alan, Flick, Matthew, Urano, Tetsumei, Ny, Tor, Cutler, Daniel, Ju, Lining A., Zhu, Cheng, Randi, Anna M., O'Donnell, James S., O'Brien, Sarah H., Fijnvandraat, Karin, Shima, Midori, Nathwani, Amit, Luyendyk, Jim, Vanhoorelbeke, Karen, Barco, Stefano, Chuansumrit, Ampaiwan, Stanworth, Simon J., Curry, Nicola, Del Rio, J. Mauricio, Battinelli, Elisabeth M., Bos, Mettine H. A., Reinhardt, Christoph, Peter, Karlheinz, Gomez, Keith, Danese, Elisa, Rak, Janusz, Flaumenhaft, Robert, Di Paola, Jorge, Nilsson, Susie, Severin, Sonia, Eto, Koji, Hitchcock, Ian S., Ni, Heyu, Despotovic, Jenny, Boilard, Eric, Rondina, Matthew, Mangin, Pierre, Hamilton, Justin R., Suzuki-Inoue, Katsue, Tsukiji, Nagaharu, Conway, Edward M., Maas, Coen, Emsley, Jonas, Jenne, Craig N., Fuchs, Tobias A., Weitz, Jeffrey, Johnsen, Jill M., Rauova, Lubica, Spyropoulos, Alex, Goto, Shinya, Verhamme, Peter, Miranda, Sebastien, Rodger, Marc, Ni Ainle, Fionnuala, Schreiber, Karen, Thomas, Moumneh, Le Gal, Gregoire, Zentner, Dominica, McLintock, Claire, and Magnusson, Maria
- Abstract
The 27th Congress of the International Society of Thrombosis and Haemostasis (ISTH) is an international conference held July 6-10, 2019, in Melbourne, the capital of the state of Victoria, Australia. The ISTH congress has previously been held every other year, with the Scientific and Standardization Committee (SSC) meeting held annually, until 2019 when it became one combined annual meeting of the ISTH and SSC. The conference covers clinical and basic aspects of hemostasis and thrombosis, and this year includes 5 Plenary lectures and >50 State of Art (SOA) lectures, presented by internationally recognized speakers, as well as numerous oral session and poster presentations selected from submitted abstracts, including many early career and reach the world support recipients. This SOA review article in RPTH contains concise Illustrated Review Articles or 'Capsules' consisting of short text, three references and a figure, with topics including stroke, cancer-associated thrombosis, hemophilia, coagulation, the interface between infection and inflammation, and in the experimental and discovery areas, megakaryocyte biology and platelet production, structure-function of key receptors and coagulation factors, and emerging new roles for thrombotic/hemostatic factors. Together, these articles highlight novel findings which will advance knowledge and with the potential to change clinical practice and improve outcomes. It is hoped that conference attendees and followers will enjoy utilizing the images for ongoing education and during the conference for live tweeting during sessions, to assist in the broadcasting and promotion of the science to those unable to attend, or who have chosen to attend a concurrent session. Use #IllustratedReview and #ISTH2019 on social media.
- Published
- 2019
- Full Text
- View/download PDF
11. Illustrated State-of-the-Art Capsules of the ISTH 2019 Congress in Melbourne, Australia : Plasminogen in wound healing
- Author
-
Andrews, Robert K., Wolberg, Alisa, Lip, Gregory Y. H., Eikelboom, John, De Meyer, Simon F., Mast, Alan, Flick, Matthew, Urano, Tetsumei, Ny, Tor, Cutler, Daniel, Ju, Lining A., Zhu, Cheng, Randi, Anna M., O'Donnell, James S., O'Brien, Sarah H., Fijnvandraat, Karin, Shima, Midori, Nathwani, Amit, Luyendyk, Jim, Vanhoorelbeke, Karen, Barco, Stefano, Chuansumrit, Ampaiwan, Stanworth, Simon J., Curry, Nicola, Del Rio, J. Mauricio, Battinelli, Elisabeth M., Bos, Mettine H. A., Reinhardt, Christoph, Peter, Karlheinz, Gomez, Keith, Danese, Elisa, Rak, Janusz, Flaumenhaft, Robert, Di Paola, Jorge, Nilsson, Susie, Severin, Sonia, Eto, Koji, Hitchcock, Ian S., Ni, Heyu, Despotovic, Jenny, Boilard, Eric, Rondina, Matthew, Mangin, Pierre, Hamilton, Justin R., Suzuki-Inoue, Katsue, Tsukiji, Nagaharu, Conway, Edward M., Maas, Coen, Emsley, Jonas, Jenne, Craig N., Fuchs, Tobias A., Weitz, Jeffrey, Johnsen, Jill M., Rauova, Lubica, Spyropoulos, Alex, Goto, Shinya, Verhamme, Peter, Miranda, Sebastien, Rodger, Marc, Ni Ainle, Fionnuala, Schreiber, Karen, Thomas, Moumneh, Le Gal, Gregoire, Zentner, Dominica, McLintock, Claire, Magnusson, Maria, Andrews, Robert K., Wolberg, Alisa, Lip, Gregory Y. H., Eikelboom, John, De Meyer, Simon F., Mast, Alan, Flick, Matthew, Urano, Tetsumei, Ny, Tor, Cutler, Daniel, Ju, Lining A., Zhu, Cheng, Randi, Anna M., O'Donnell, James S., O'Brien, Sarah H., Fijnvandraat, Karin, Shima, Midori, Nathwani, Amit, Luyendyk, Jim, Vanhoorelbeke, Karen, Barco, Stefano, Chuansumrit, Ampaiwan, Stanworth, Simon J., Curry, Nicola, Del Rio, J. Mauricio, Battinelli, Elisabeth M., Bos, Mettine H. A., Reinhardt, Christoph, Peter, Karlheinz, Gomez, Keith, Danese, Elisa, Rak, Janusz, Flaumenhaft, Robert, Di Paola, Jorge, Nilsson, Susie, Severin, Sonia, Eto, Koji, Hitchcock, Ian S., Ni, Heyu, Despotovic, Jenny, Boilard, Eric, Rondina, Matthew, Mangin, Pierre, Hamilton, Justin R., Suzuki-Inoue, Katsue, Tsukiji, Nagaharu, Conway, Edward M., Maas, Coen, Emsley, Jonas, Jenne, Craig N., Fuchs, Tobias A., Weitz, Jeffrey, Johnsen, Jill M., Rauova, Lubica, Spyropoulos, Alex, Goto, Shinya, Verhamme, Peter, Miranda, Sebastien, Rodger, Marc, Ni Ainle, Fionnuala, Schreiber, Karen, Thomas, Moumneh, Le Gal, Gregoire, Zentner, Dominica, McLintock, Claire, and Magnusson, Maria
- Abstract
The 27th Congress of the International Society of Thrombosis and Haemostasis (ISTH) is an international conference held July 6-10, 2019, in Melbourne, the capital of the state of Victoria, Australia. The ISTH congress has previously been held every other year, with the Scientific and Standardization Committee (SSC) meeting held annually, until 2019 when it became one combined annual meeting of the ISTH and SSC. The conference covers clinical and basic aspects of hemostasis and thrombosis, and this year includes 5 Plenary lectures and >50 State of Art (SOA) lectures, presented by internationally recognized speakers, as well as numerous oral session and poster presentations selected from submitted abstracts, including many early career and reach the world support recipients. This SOA review article in RPTH contains concise Illustrated Review Articles or 'Capsules' consisting of short text, three references and a figure, with topics including stroke, cancer-associated thrombosis, hemophilia, coagulation, the interface between infection and inflammation, and in the experimental and discovery areas, megakaryocyte biology and platelet production, structure-function of key receptors and coagulation factors, and emerging new roles for thrombotic/hemostatic factors. Together, these articles highlight novel findings which will advance knowledge and with the potential to change clinical practice and improve outcomes. It is hoped that conference attendees and followers will enjoy utilizing the images for ongoing education and during the conference for live tweeting during sessions, to assist in the broadcasting and promotion of the science to those unable to attend, or who have chosen to attend a concurrent session. Use #IllustratedReview and #ISTH2019 on social media.
- Published
- 2019
- Full Text
- View/download PDF
12. Illustrated State-of-the-Art Capsules of the ISTH 2019 Congress in Melbourne, Australia : Plasminogen in wound healing
- Author
-
Andrews, Robert K., Wolberg, Alisa, Lip, Gregory Y. H., Eikelboom, John, De Meyer, Simon F., Mast, Alan, Flick, Matthew, Urano, Tetsumei, Ny, Tor, Cutler, Daniel, Ju, Lining A., Zhu, Cheng, Randi, Anna M., O'Donnell, James S., O'Brien, Sarah H., Fijnvandraat, Karin, Shima, Midori, Nathwani, Amit, Luyendyk, Jim, Vanhoorelbeke, Karen, Barco, Stefano, Chuansumrit, Ampaiwan, Stanworth, Simon J., Curry, Nicola, Del Rio, J. Mauricio, Battinelli, Elisabeth M., Bos, Mettine H. A., Reinhardt, Christoph, Peter, Karlheinz, Gomez, Keith, Danese, Elisa, Rak, Janusz, Flaumenhaft, Robert, Di Paola, Jorge, Nilsson, Susie, Severin, Sonia, Eto, Koji, Hitchcock, Ian S., Ni, Heyu, Despotovic, Jenny, Boilard, Eric, Rondina, Matthew, Mangin, Pierre, Hamilton, Justin R., Suzuki-Inoue, Katsue, Tsukiji, Nagaharu, Conway, Edward M., Maas, Coen, Emsley, Jonas, Jenne, Craig N., Fuchs, Tobias A., Weitz, Jeffrey, Johnsen, Jill M., Rauova, Lubica, Spyropoulos, Alex, Goto, Shinya, Verhamme, Peter, Miranda, Sebastien, Rodger, Marc, Ni Ainle, Fionnuala, Schreiber, Karen, Thomas, Moumneh, Le Gal, Gregoire, Zentner, Dominica, McLintock, Claire, Magnusson, Maria, Andrews, Robert K., Wolberg, Alisa, Lip, Gregory Y. H., Eikelboom, John, De Meyer, Simon F., Mast, Alan, Flick, Matthew, Urano, Tetsumei, Ny, Tor, Cutler, Daniel, Ju, Lining A., Zhu, Cheng, Randi, Anna M., O'Donnell, James S., O'Brien, Sarah H., Fijnvandraat, Karin, Shima, Midori, Nathwani, Amit, Luyendyk, Jim, Vanhoorelbeke, Karen, Barco, Stefano, Chuansumrit, Ampaiwan, Stanworth, Simon J., Curry, Nicola, Del Rio, J. Mauricio, Battinelli, Elisabeth M., Bos, Mettine H. A., Reinhardt, Christoph, Peter, Karlheinz, Gomez, Keith, Danese, Elisa, Rak, Janusz, Flaumenhaft, Robert, Di Paola, Jorge, Nilsson, Susie, Severin, Sonia, Eto, Koji, Hitchcock, Ian S., Ni, Heyu, Despotovic, Jenny, Boilard, Eric, Rondina, Matthew, Mangin, Pierre, Hamilton, Justin R., Suzuki-Inoue, Katsue, Tsukiji, Nagaharu, Conway, Edward M., Maas, Coen, Emsley, Jonas, Jenne, Craig N., Fuchs, Tobias A., Weitz, Jeffrey, Johnsen, Jill M., Rauova, Lubica, Spyropoulos, Alex, Goto, Shinya, Verhamme, Peter, Miranda, Sebastien, Rodger, Marc, Ni Ainle, Fionnuala, Schreiber, Karen, Thomas, Moumneh, Le Gal, Gregoire, Zentner, Dominica, McLintock, Claire, and Magnusson, Maria
- Abstract
The 27th Congress of the International Society of Thrombosis and Haemostasis (ISTH) is an international conference held July 6-10, 2019, in Melbourne, the capital of the state of Victoria, Australia. The ISTH congress has previously been held every other year, with the Scientific and Standardization Committee (SSC) meeting held annually, until 2019 when it became one combined annual meeting of the ISTH and SSC. The conference covers clinical and basic aspects of hemostasis and thrombosis, and this year includes 5 Plenary lectures and >50 State of Art (SOA) lectures, presented by internationally recognized speakers, as well as numerous oral session and poster presentations selected from submitted abstracts, including many early career and reach the world support recipients. This SOA review article in RPTH contains concise Illustrated Review Articles or 'Capsules' consisting of short text, three references and a figure, with topics including stroke, cancer-associated thrombosis, hemophilia, coagulation, the interface between infection and inflammation, and in the experimental and discovery areas, megakaryocyte biology and platelet production, structure-function of key receptors and coagulation factors, and emerging new roles for thrombotic/hemostatic factors. Together, these articles highlight novel findings which will advance knowledge and with the potential to change clinical practice and improve outcomes. It is hoped that conference attendees and followers will enjoy utilizing the images for ongoing education and during the conference for live tweeting during sessions, to assist in the broadcasting and promotion of the science to those unable to attend, or who have chosen to attend a concurrent session. Use #IllustratedReview and #ISTH2019 on social media.
- Published
- 2019
- Full Text
- View/download PDF
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