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Research abounds on deploying interventions to support peer interactions between children on the autism spectrum (AS) and neurotypical children [1‐2]. Technological advancements such as eye tracking devices have provided ample affordances to the field of autism research in terms of facilitating the collection of insightful data related to the gaze-based interaction behaviour of children on the AS [3]. Yet, further empirical understanding on how children interact within inclusive educational contexts is needed [4]. Addressing this gap, we present our research study set in a naturalistic inclusive school environment in which small groups of three children interact playing a boardgame, Alias, while wearing mobile eye tracking glasses. Alias is a word game during which a person guesses the word that another person is explaining by giving them hints and tips. In our study, we analysed the game play by focusing on 3 roles: an explainer, as the person giving clues for a guesser to guess what the word was, while an observer watched the interactions. 25 children (age 10‐12 years, 4th ‐ 5th grade, 15 males) from 3 different schools in Finland participated in the study. For data analysis, 2 categories were used: children with no diagnosis (n=19) and children on the autism spectrum (AS) (n=6). 43 data collection sessions of about 45 minutes each were carried out. Each session was set so that a small inclusive group of 3 children, each wearing mobile eye tracking glasses (Tobii Glasses 2), engaged for 10 minutes in a ludative task planned by the researchers and for 25 minutes in a curricular task planned by the teacher. Here we present the analysis of 9 sessions during which Alias was used. The mobile eye tracking glasses data collected was coded using Tobii Pro Lab. We analysed the children’s gaze behaviour from the perspective of the role taken, focusing on the proportion of time that the children spent looking at three areas of interest: other children’s faces, the t

The cathodic delamination and wear resistance of epoxy powder coatings were evaluated after adding 3 % (by wt.) of calcium ion exchanged micropigments from amorphous synthetic silica. The materials were manufactured through the innovative and economical hot mixing method, and three different coatings were considered: commercial epoxy, epoxy without micropigments submitted to the hot mixing treatment, and epoxy with micropigments. The curing kinetics of the powder coatings was studied in order to evaluate the possible effects of the micropigments on the epoxy, using differential scanning calorimetry (DSC). In addition, mechanical properties of coatings (hardness and scratch resistance) and their wear resistance (reciprocal tribometer tests) were assessed. After provoking a controlled mechanical failure in the coatings, their delamination resistance was analyzed by scanning Kelvin probe (SKP). The delamination front was calculated after adding a drop of 3.5 % NaCl solution and taking measurements for 26 days. The results show that the corrosion attack progresses through a cathodic delamination mechanism. The addition of corrosion inhibitors in epoxy powder coatings has not only allowed a considerable improvement in delamination resistance, but has also led to greater mechanical and wear resistance. At the same time, it has simultaneously reduced the chances for mechanical failure of the coating and decreased the progression rate of damage, if it occurs. The study has also been completed with electrochemical impedance spectroscopy and polarization measured of fully-immersed defective coatings in 3.5 % NaCl.

Conclusiónes :1) Creemos sinceramente que la programación de prácticas clínicas en atención primaria ES UN HECHO BENEFICIOSO para la formación del futuro graduado en medicina, aunque sea en primero de Grado.. • 2) Hemos observado que la presencia de los alumnos en el Centro de Salud , crea MENTORÍA INVERSA en los profesionales sanitarios.

INTRODUCCIÓN El período de formación Doctoral es estratégico para la creación de futuros investigadores que gestionen adecuadamente el conocimiento en Ciencias de la Salud. Pero la investigación no sólo tiene contenidos positivos de ciencia sino que además debe de poseer ciertos valores intrínsecos (axiología) de los que cuidan los Comités de Ética de la Investigación. METODOLOGÍA Y OBSERVACIÓN PERSONAL En el Grupo AL-ANDALUS se planteó la posibilidad de dirigir Tesis Doctorales a la promoción de residentes de Medicina Familiar y Comunitaria del año 2014 (30 médicos postgraduados) en los tres hospitales de la ciudad de Sevilla. Se les citó a una sesión restringida y voluntaria para exponer sus ideas y deseos de realización de Tesis. Sólo se presentaron a la sesión tres postgraduadas que disertaron sobre sus inquietudes. Fueron unos 45 minutos inolvidables, llenos de ilusión y de fe en el futuro investigador los que proporcionaron aquellas residentes , que son en la actualidad jóvenes médicos de familia en puestos de responsabilidad asistencial. Aquello se conformó como una “SESIÓN AXIOLÓGICA DE POSTULACIÓN DE TESIS” , con los proyectos aún no asignados , con directores en fase de selección de doctorandos y viceversa [i] , pero con una frescura intelectual y con una exposición de valores más que sobresaliente. La Escuela Internacional de Doctorado de la Universidad de Sevilla (EIDUS) organiza en la actualidad un concurso denominado Tesis en Tres Minutos que se desarrolla anualmente y que tuvo su origen en la Universidad de Queensland (Australia) [ii] [iii]. Nosotros desarrollaríamos una iniciativa paralela que complementaría, creemos , el panel formativo de la EIDUS. Se podrían organizar dos sesiones anuales, una para Departamentos Pre-clínicos (investigación básica) y otra para Clínicos (Investigación clínica y sanitaria). Serían intervenciones cortas pero intensas [iv] [v] de los trabajos de investigación postulados en el terreno de los valores de la ciencia [vi].

Conclusiónes :1) Creemos sinceramente que la programación de prácticas clínicas en atención primaria ES UN HECHO BENEFICIOSO para la formación del futuro graduado en medicina, aunque sea en primero de Grado.. • 2) Hemos observado que la presencia de los alumnos en el Centro de Salud , crea MENTORÍA INVERSA en los profesionales sanitarios.

INTRODUCCIÓN El período de formación Doctoral es estratégico para la creación de futuros investigadores que gestionen adecuadamente el conocimiento en Ciencias de la Salud. Pero la investigación no sólo tiene contenidos positivos de ciencia sino que además debe de poseer ciertos valores intrínsecos (axiología) de los que cuidan los Comités de Ética de la Investigación. METODOLOGÍA Y OBSERVACIÓN PERSONAL En el Grupo AL-ANDALUS se planteó la posibilidad de dirigir Tesis Doctorales a la promoción de residentes de Medicina Familiar y Comunitaria del año 2014 (30 médicos postgraduados) en los tres hospitales de la ciudad de Sevilla. Se les citó a una sesión restringida y voluntaria para exponer sus ideas y deseos de realización de Tesis. Sólo se presentaron a la sesión tres postgraduadas que disertaron sobre sus inquietudes. Fueron unos 45 minutos inolvidables, llenos de ilusión y de fe en el futuro investigador los que proporcionaron aquellas residentes , que son en la actualidad jóvenes médicos de familia en puestos de responsabilidad asistencial. Aquello se conformó como una “SESIÓN AXIOLÓGICA DE POSTULACIÓN DE TESIS” , con los proyectos aún no asignados , con directores en fase de selección de doctorandos y viceversa [i] , pero con una frescura intelectual y con una exposición de valores más que sobresaliente. La Escuela Internacional de Doctorado de la Universidad de Sevilla (EIDUS) organiza en la actualidad un concurso denominado Tesis en Tres Minutos que se desarrolla anualmente y que tuvo su origen en la Universidad de Queensland (Australia) [ii] [iii]. Nosotros desarrollaríamos una iniciativa paralela que complementaría, creemos , el panel formativo de la EIDUS. Se podrían organizar dos sesiones anuales, una para Departamentos Pre-clínicos (investigación básica) y otra para Clínicos (Investigación clínica y sanitaria). Serían intervenciones cortas pero intensas [iv] [v] de los trabajos de investigación postulados en el terreno de los valores de la ciencia [vi].

Conclusiónes :1) Creemos sinceramente que la programación de prácticas clínicas en atención primaria ES UN HECHO BENEFICIOSO para la formación del futuro graduado en medicina, aunque sea en primero de Grado.. • 2) Hemos observado que la presencia de los alumnos en el Centro de Salud , crea MENTORÍA INVERSA en los profesionales sanitarios.

INTRODUCCIÓN El período de formación Doctoral es estratégico para la creación de futuros investigadores que gestionen adecuadamente el conocimiento en Ciencias de la Salud. Pero la investigación no sólo tiene contenidos positivos de ciencia sino que además debe de poseer ciertos valores intrínsecos (axiología) de los que cuidan los Comités de Ética de la Investigación. METODOLOGÍA Y OBSERVACIÓN PERSONAL En el Grupo AL-ANDALUS se planteó la posibilidad de dirigir Tesis Doctorales a la promoción de residentes de Medicina Familiar y Comunitaria del año 2014 (30 médicos postgraduados) en los tres hospitales de la ciudad de Sevilla. Se les citó a una sesión restringida y voluntaria para exponer sus ideas y deseos de realización de Tesis. Sólo se presentaron a la sesión tres postgraduadas que disertaron sobre sus inquietudes. Fueron unos 45 minutos inolvidables, llenos de ilusión y de fe en el futuro investigador los que proporcionaron aquellas residentes , que son en la actualidad jóvenes médicos de familia en puestos de responsabilidad asistencial. Aquello se conformó como una “SESIÓN AXIOLÓGICA DE POSTULACIÓN DE TESIS” , con los proyectos aún no asignados , con directores en fase de selección de doctorandos y viceversa [i] , pero con una frescura intelectual y con una exposición de valores más que sobresaliente. La Escuela Internacional de Doctorado de la Universidad de Sevilla (EIDUS) organiza en la actualidad un concurso denominado Tesis en Tres Minutos que se desarrolla anualmente y que tuvo su origen en la Universidad de Queensland (Australia) [ii] [iii]. Nosotros desarrollaríamos una iniciativa paralela que complementaría, creemos , el panel formativo de la EIDUS. Se podrían organizar dos sesiones anuales, una para Departamentos Pre-clínicos (investigación básica) y otra para Clínicos (Investigación clínica y sanitaria). Serían intervenciones cortas pero intensas [iv] [v] de los trabajos de investigación postulados en el terreno de los valores de la ciencia [vi].

INTRODUCCIÓN El período de formación Doctoral es estratégico para la creación de futuros investigadores que gestionen adecuadamente el conocimiento en Ciencias de la Salud. Pero la investigación no sólo tiene contenidos positivos de ciencia sino que además debe de poseer ciertos valores intrínsecos (axiología) de los que cuidan los Comités de Ética de la Investigación. METODOLOGÍA Y OBSERVACIÓN PERSONAL En el Grupo AL-ANDALUS se planteó la posibilidad de dirigir Tesis Doctorales a la promoción de residentes de Medicina Familiar y Comunitaria del año 2014 (30 médicos postgraduados) en los tres hospitales de la ciudad de Sevilla. Se les citó a una sesión restringida y voluntaria para exponer sus ideas y deseos de realización de Tesis. Sólo se presentaron a la sesión tres postgraduadas que disertaron sobre sus inquietudes. Fueron unos 45 minutos inolvidables, llenos de ilusión y de fe en el futuro investigador los que proporcionaron aquellas residentes , que son en la actualidad jóvenes médicos de familia en puestos de responsabilidad asistencial. Aquello se conformó como una “SESIÓN AXIOLÓGICA DE POSTULACIÓN DE TESIS” , con los proyectos aún no asignados , con directores en fase de selección de doctorandos y viceversa [i] , pero con una frescura intelectual y con una exposición de valores más que sobresaliente. La Escuela Internacional de Doctorado de la Universidad de Sevilla (EIDUS) organiza en la actualidad un concurso denominado Tesis en Tres Minutos que se desarrolla anualmente y que tuvo su origen en la Universidad de Queensland (Australia) [ii] [iii]. Nosotros desarrollaríamos una iniciativa paralela que complementaría, creemos , el panel formativo de la EIDUS. Se podrían organizar dos sesiones anuales, una para Departamentos Pre-clínicos (investigación básica) y otra para Clínicos (Investigación clínica y sanitaria). Serían intervenciones cortas pero intensas [iv] [v] de los trabajos de investigación postulados en el terreno de los valores de la ciencia [vi].

Introduction and objective: To carry out a update review on the current diagnoses and therapeutic indications of tear duct obstruction (NLO) and propose a simple, early and practical clinical management. Method: Review of published literature regarding NLO and the current way of approaching this pathology. Results: The alteration of the natural tear flow (epiphora) may have a functional or anatomical origin. Functional obstructions are secondary to the failure of the tear pump, while the anatomical obstruction is caused by a physical obstacle along the tear duct that prevents drainage in the nasal cavity. Pseudoepiphora (tearing), on the other hand, is secondary to the presence of pathology of the ocular surface (dry eye) or secondary to mechanical, chemical, infectious or psychic stimuli. Up to 40% of patients referred to ophthalmology consultations for tearing / epiphora, have a dry eye with tear reflex, without anatomical obstruction of the tear duct. Conclusions: Tearing is one of the most frequent symptoms in ophthalmology consultations. However, the etiological factors that can lead to this complaint are very numerous. A multidisciplinary study (ophthalmology and ENT) is essential to make a correct etiological diagnosis. The success of tear surgery lies in a correct surgical indication., Introducción y objetivo: Realizar una revisión y actualización del diagnóstico e indicaciones terapéuticas de la obstrucción de la vía nasolagrimal (ONL), así como un abordaje clínico sencillo, precoz y práctico. Método: revisión de la literatura publicada referente a la ONL y sobre la manera actual de enfocar esta patología. Resultados: El lagrimeo excesivo (epífora) puede tener un origen funcional o anatómico. Las obstrucciones funcionales son secundarias al fracaso de la bomba lagrimal, mientras que la obstrucción anatómica es causada por un obstáculo físico a lo largo de la vía lagrimal que impide el drenaje de la misma en la cavidad nasal. La pseudoepífora (lagrimeo reflejo), por el contrario, es secundaria a la presencia de patología de la superficie ocular (ojo seco) o a estímulos mecánicos, químicos, infecciosos o psíquicos. Hasta un 40% de los pacientes referidos a consultas de oftalmología por lagrimeo/epífora, presentan un ojo seco con lagrimeo reflejo, sin obstrucción anatómica de la vía lagrimal. Conclusiones: El lagrimeo es uno de los síntomas más frecuentes en las consultas de oftalmología. Sin embargo, son muy numerosos los factores etiológicos que pueden conducir a esta queja. Es fundamental un estudio multidisciplinar (oftalmología y otorrinolaringología) para realizar un correcto diagnóstico. El éxito de la cirugía lagrimal reside en una correcta indicación quirúrgica.

Conclusiónes :1) Creemos sinceramente que la programación de prácticas clínicas en atención primaria ES UN HECHO BENEFICIOSO para la formación del futuro graduado en medicina, aunque sea en primero de Grado.. • 2) Hemos observado que la presencia de los alumnos en el Centro de Salud , crea MENTORÍA INVERSA en los profesionales sanitarios.

Conclusiónes :1) Creemos sinceramente que la programación de prácticas clínicas en atención primaria ES UN HECHO BENEFICIOSO para la formación del futuro graduado en medicina, aunque sea en primero de Grado.. • 2) Hemos observado que la presencia de los alumnos en el Centro de Salud , crea MENTORÍA INVERSA en los profesionales sanitarios.

INTRODUCCIÓN El período de formación Doctoral es estratégico para la creación de futuros investigadores que gestionen adecuadamente el conocimiento en Ciencias de la Salud. Pero la investigación no sólo tiene contenidos positivos de ciencia sino que además debe de poseer ciertos valores intrínsecos (axiología) de los que cuidan los Comités de Ética de la Investigación. METODOLOGÍA Y OBSERVACIÓN PERSONAL En el Grupo AL-ANDALUS se planteó la posibilidad de dirigir Tesis Doctorales a la promoción de residentes de Medicina Familiar y Comunitaria del año 2014 (30 médicos postgraduados) en los tres hospitales de la ciudad de Sevilla. Se les citó a una sesión restringida y voluntaria para exponer sus ideas y deseos de realización de Tesis. Sólo se presentaron a la sesión tres postgraduadas que disertaron sobre sus inquietudes. Fueron unos 45 minutos inolvidables, llenos de ilusión y de fe en el futuro investigador los que proporcionaron aquellas residentes , que son en la actualidad jóvenes médicos de familia en puestos de responsabilidad asistencial. Aquello se conformó como una “SESIÓN AXIOLÓGICA DE POSTULACIÓN DE TESIS” , con los proyectos aún no asignados , con directores en fase de selección de doctorandos y viceversa [i] , pero con una frescura intelectual y con una exposición de valores más que sobresaliente. La Escuela Internacional de Doctorado de la Universidad de Sevilla (EIDUS) organiza en la actualidad un concurso denominado Tesis en Tres Minutos que se desarrolla anualmente y que tuvo su origen en la Universidad de Queensland (Australia) [ii] [iii]. Nosotros desarrollaríamos una iniciativa paralela que complementaría, creemos , el panel formativo de la EIDUS. Se podrían organizar dos sesiones anuales, una para Departamentos Pre-clínicos (investigación básica) y otra para Clínicos (Investigación clínica y sanitaria). Serían intervenciones cortas pero intensas [iv] [v] de los trabajos de investigación postulados en el terreno de los valores de la ciencia [vi].

Chronic venous insufficiency (CVI), in which blood return to the heart is impaired, is a prevalent condition worldwide. Valve incompetence is a complication of CVI that results in blood reflux, thereby aggravating venous hypertension. While CVI has a complex course and is known to produce alterations in the vein wall, the underlying pathological mechanisms remain unclear. This study examined the presence of DNA damage, pro-inflammatory cytokines and extracellular matrix remodelling in CVI-related valve incompetence. One hundred and ten patients with CVI were reviewed and divided into four groups according to age (<50 and ≥50 years) and a clinical diagnosis of venous reflux indicating venous system valve incompetence (R) (n = 81) or no reflux (NR) (n = 29). In vein specimens (greater saphenous vein) from each group, PARP, IL-17, COL-I, COL-III, MMP-2 and TIMP-2 expression levels were determined by RT-qPCR and immunohistochemistry. The younger patients with valve incompetence showed significantly higher PARP, IL-17, COL-I, COL-III, MMP-2 and reduced TIMP-2 expression levels and a higher COL-I/III ratio. Young CVI patients with venous reflux suffer chronic DNA damage, with consequences at both the local tissue and systemic levels, possibly associated with ageing.

The worldwide prevalence of insufficient physical activity (PA) and prolonged sedentary behavior (SB) were high before the coronavirus (COVID-19) pandemic. Measures that were taken by governments (such as home confinement) to control the spread of COVID-19 may have affected levels of PA and SB. This cross-sectional study among South American adults during the first months of COVID-19 aims to (i) compare sitting time (ST), screen exposure, moderate PA (MPA), vigorous PA (VPA), and moderate-to-vigorous PA (MVPA) before and during lockdown to sociodemographic correlates and (ii) to assess the impact of lockdown on combinations of groups reporting meeting/not-meeting PA recommendations and engaging/not-engaging excessive ST (≥7 h/day). Bivariate associations, effect sizes, and multivariable linear regressions were used. Adults from Argentina (n = 575) and Chile (n = 730) completed an online survey with questions regarding demographics, lifestyle factors, and chronic diseases. Mean reductions of 42.7 and 22.0 min./day were shown in MPA and VPA, respectively; while increases of 212.4 and 164.3 min./day were observed in screen and ST, respectively. Those who met PA recommendations and spent <7 h/day of ST experienced greatest changes, reporting greater than 3 h/day higher ST and more than 1.5 h/day lower MVPA. Findings from the present study suggest that efforts to promote PA to South American adults during and after COVID-19 restrictions are needed.

The worldwide prevalence of insufficient physical activity (PA) and prolonged sedentary behavior (SB) were high before the coronavirus (COVID-19) pandemic. Measures that were taken by governments (such as home confinement) to control the spread of COVID-19 may have affected levels of PA and SB. This cross-sectional study among South American adults during the first months of COVID-19 aims to (i) compare sitting time (ST), screen exposure, moderate PA (MPA), vigorous PA (VPA), and moderate-to-vigorous PA (MVPA) before and during lockdown to sociodemographic correlates and (ii) to assess the impact of lockdown on combinations of groups reporting meeting/not-meeting PA recommendations and engaging/not-engaging excessive ST (≥7 h/day). Bivariate associations, effect sizes, and multivariable linear regressions were used. Adults from Argentina (n = 575) and Chile (n = 730) completed an online survey with questions regarding demographics, lifestyle factors, and chronic diseases. Mean reductions of 42.7 and 22.0 min./day were shown in MPA and VPA, respectively; while increases of 212.4 and 164.3 min./day were observed in screen and ST, respectively. Those who met PA recommendations and spent <7 h/day of ST experienced greatest changes, reporting greater than 3 h/day higher ST and more than 1.5 h/day lower MVPA. Findings from the present study suggest that efforts to promote PA to South American adults during and after COVID-19 restrictions are needed.

Given the obstetric and metabolic importance of Gestational Diabetes, we wanted to study the correlations ofthe first trimester biomarkers with the weight ofthe fetus at 20 weeks and with that of the mother at 28 weeks of gestation for pregnant women with and without gestational diabetes in a research carried out in primary care. This is an observational study of cases and controls. The quantitative variables analyzed were: PAPPA (Pregnancy Associated Plasma Protein A) (mU / ml), Betahydroxychorionic (ngrs / ml), TSH (µUI / ml) and free T4 (ngrs / dl) at 12 weeks, fetal weight at 20 weeks and maternal weight in kilograms at 28 weeks. As a descriptive balancing variable, we have used the age of the pregnant woman in years. Six health centers of the Primary Healthcare District of Seville (Spain) have been sampled. We applied simple linear regression using the least squares method and the smoothing technique called LOESS (Locally Weighted Scatterplot Smoothing). A finding was highlighted above all the others, the inverse correlations and the least squares lines of the PAPP-A and TSH variables at 12 weeks of gestation, and the correlations between fetal weight at 20 weeks with Betahydroxychorionic and with PAPPA. The most important is the first because of the change and the magnitude of Pearson's R2 (+0.10) in pregnant women with gestational diabetes. We have found a noticeable change in the correlation of PAPPA with TSH in pregnant women with Gestational Diabetes. The upper confidence interval of the Pearson correlation coefficient reaches +0. 3 . A possible pathophysiological explanation for this correlation found in our work could be the action ofTSH on insulin-like growth factors in human osteoblastic cells.

Given the obstetric and metabolic importance of Gestational Diabetes, we wanted to study the correlations ofthe first trimester biomarkers with the weight ofthe fetus at 20 weeks and with that of the mother at 28 weeks of gestation for pregnant women with and without gestational diabetes in a research carried out in primary care. This is an observational study of cases and controls. The quantitative variables analyzed were: PAPPA (Pregnancy Associated Plasma Protein A) (mU / ml), Betahydroxychorionic (ngrs / ml), TSH (µUI / ml) and free T4 (ngrs / dl) at 12 weeks, fetal weight at 20 weeks and maternal weight in kilograms at 28 weeks. As a descriptive balancing variable, we have used the age of the pregnant woman in years. Six health centers of the Primary Healthcare District of Seville (Spain) have been sampled. We applied simple linear regression using the least squares method and the smoothing technique called LOESS (Locally Weighted Scatterplot Smoothing). A finding was highlighted above all the others, the inverse correlations and the least squares lines of the PAPP-A and TSH variables at 12 weeks of gestation, and the correlations between fetal weight at 20 weeks with Betahydroxychorionic and with PAPPA. The most important is the first because of the change and the magnitude of Pearson's R2 (+0.10) in pregnant women with gestational diabetes. We have found a noticeable change in the correlation of PAPPA with TSH in pregnant women with Gestational Diabetes. The upper confidence interval of the Pearson correlation coefficient reaches +0. 3 . A possible pathophysiological explanation for this correlation found in our work could be the action ofTSH on insulin-like growth factors in human osteoblastic cells.

Given the obstetric and metabolic importance of Gestational Diabetes, we wanted to study the correlations ofthe first trimester biomarkers with the weight ofthe fetus at 20 weeks and with that of the mother at 28 weeks of gestation for pregnant women with and without gestational diabetes in a research carried out in primary care. This is an observational study of cases and controls. The quantitative variables analyzed were: PAPPA (Pregnancy Associated Plasma Protein A) (mU / ml), Betahydroxychorionic (ngrs / ml), TSH (µUI / ml) and free T4 (ngrs / dl) at 12 weeks, fetal weight at 20 weeks and maternal weight in kilograms at 28 weeks. As a descriptive balancing variable, we have used the age of the pregnant woman in years. Six health centers of the Primary Healthcare District of Seville (Spain) have been sampled. We applied simple linear regression using the least squares method and the smoothing technique called LOESS (Locally Weighted Scatterplot Smoothing). A finding was highlighted above all the others, the inverse correlations and the least squares lines of the PAPP-A and TSH variables at 12 weeks of gestation, and the correlations between fetal weight at 20 weeks with Betahydroxychorionic and with PAPPA. The most important is the first because of the change and the magnitude of Pearson's R2 (+0.10) in pregnant women with gestational diabetes. We have found a noticeable change in the correlation of PAPPA with TSH in pregnant women with Gestational Diabetes. The upper confidence interval of the Pearson correlation coefficient reaches +0. 3 . A possible pathophysiological explanation for this correlation found in our work could be the action ofTSH on insulin-like growth factors in human osteoblastic cells.

Given the obstetric and metabolic importance of Gestational Diabetes, we wanted to study the correlations ofthe first trimester biomarkers with the weight ofthe fetus at 20 weeks and with that of the mother at 28 weeks of gestation for pregnant women with and without gestational diabetes in a research carried out in primary care. This is an observational study of cases and controls. The quantitative variables analyzed were: PAPPA (Pregnancy Associated Plasma Protein A) (mU / ml), Betahydroxychorionic (ngrs / ml), TSH (µUI / ml) and free T4 (ngrs / dl) at 12 weeks, fetal weight at 20 weeks and maternal weight in kilograms at 28 weeks. As a descriptive balancing variable, we have used the age of the pregnant woman in years. Six health centers of the Primary Healthcare District of Seville (Spain) have been sampled. We applied simple linear regression using the least squares method and the smoothing technique called LOESS (Locally Weighted Scatterplot Smoothing). A finding was highlighted above all the others, the inverse correlations and the least squares lines of the PAPP-A and TSH variables at 12 weeks of gestation, and the correlations between fetal weight at 20 weeks with Betahydroxychorionic and with PAPPA. The most important is the first because of the change and the magnitude of Pearson's R2 (+0.10) in pregnant women with gestational diabetes. We have found a noticeable change in the correlation of PAPPA with TSH in pregnant women with Gestational Diabetes. The upper confidence interval of the Pearson correlation coefficient reaches +0. 3 . A possible pathophysiological explanation for this correlation found in our work could be the action ofTSH on insulin-like growth factors in human osteoblastic cells.

Given the obstetric and metabolic importance of Gestational Diabetes, we wanted to study the correlations ofthe first trimester biomarkers with the weight ofthe fetus at 20 weeks and with that of the mother at 28 weeks of gestation for pregnant women with and without gestational diabetes in a research carried out in primary care. This is an observational study of cases and controls. The quantitative variables analyzed were: PAPPA (Pregnancy Associated Plasma Protein A) (mU / ml), Betahydroxychorionic (ngrs / ml), TSH (µUI / ml) and free T4 (ngrs / dl) at 12 weeks, fetal weight at 20 weeks and maternal weight in kilograms at 28 weeks. As a descriptive balancing variable, we have used the age of the pregnant woman in years. Six health centers of the Primary Healthcare District of Seville (Spain) have been sampled. We applied simple linear regression using the least squares method and the smoothing technique called LOESS (Locally Weighted Scatterplot Smoothing). A finding was highlighted above all the others, the inverse correlations and the least squares lines of the PAPP-A and TSH variables at 12 weeks of gestation, and the correlations between fetal weight at 20 weeks with Betahydroxychorionic and with PAPPA. The most important is the first because of the change and the magnitude of Pearson's R2 (+0.10) in pregnant women with gestational diabetes. We have found a noticeable change in the correlation of PAPPA with TSH in pregnant women with Gestational Diabetes. The upper confidence interval of the Pearson correlation coefficient reaches +0. 3 . A possible pathophysiological explanation for this correlation found in our work could be the action ofTSH on insulin-like growth factors in human osteoblastic cells.

Background: The prominence of sedentary behavior research in health science has grown rapidly. With this growth there is increasing urgency for clear, common and accepted terminology and definitions. Such standardization is difficult to achieve, especially across multi-disciplinary researchers, practitioners, and industries. The Sedentary Behavior Research Network (SBRN) undertook a Terminology Consensus Project to address this need. Method: First, a literature review was completed to identify key terms in sedentary behavior research. These key terms were then reviewed and modified by a Steering Committee formed by SBRN. Next, SBRN members were invited to contribute to this project and interested participants reviewed and provided feedback on the proposed list of terms and draft definitions through an online survey. Finally, a conceptual model and consensus definitions (including caveats and examples for all age groups and functional abilities) were finalized based on the feedback received from the 87 SBRN member participants who responded to the original invitation and survey. Results: Consensus definitions for the terms physical inactivity, stationary behavior, sedentary behavior, standing, screen time, non-screen-based sedentary time, sitting, reclining, lying, sedentary behavior pattern, as well as how the terms bouts, breaks, and interruptions should be used in this context are provided. Conclusion: It is hoped that the definitions resulting from this comprehensive, transparent, and broad-based participatory process will result in standardized terminology that is widely supported and adopted, thereby advancing future research, interventions, policies, and practices related to sedentary behaviors.

© 2016 Springer Science+Business Media New YorkIn human culture, storytelling is a long-established tradition. The reasons people tell stories are manifold: to entertain, to transfer knowledge between generations, to maintain cultural heritage, or to warn others of dangers. With the emergence of the digitisation of media, many new possibilities to tell stories in serious and non-entertainment contexts emerged. A very simple example is the idea of serious gaming, as in, digital games without the primary purpose of entertainment. In this paper, we introduce the term serious storytelling as a new potential media genre – defining serious storytelling as storytelling with a purpose beyond entertainment. We also put forward a review of existing potential application areas, and develop a framework for serious storytelling. We foresee several application areas for this fundamental concept, including wellbeing and health, medicine, psychology, education, ethical problem solving, e-leadership and management, qualitative journalism, serious digital games, simulations and virtual training, user experience studies, and online communication.

The authors analyze China's impact on U.S.-Canadian trade. Despite Canada's having lost its historic position as the United States' first trade partner due to the hike in Chinese exports to the U.S. market, this has not affected the structure of their commercial operations. Chinese exports to the U.S. are mainly labor- and capital-intensive manufactured goods, while Canadian exports are mainly natural resources and services. In addition, the two countries have defense and security accords that facilitate trade and allow the United States to deal better with external threats., En este artículo se analiza el impacto comercial de China en el comercio entre Canadá y Estados Unidos. A pesar de que Canadá perdió su posición histórica como primer socio comercial de Estados Unidos, debido al ascenso de las exportaciones de China al mercado estadunidense, esto no ha afectado la estructura de sus intercambios comerciales. Las exportaciones chinas a Estados Unidos son principalmente manufacturas intensivas en mano de obra y capital, en tanto que las exportaciones canadienses son principalmente de recursos naturales y servicios. Además, ambos países tienen acuerdos de defensa y seguridad que agilizan el comercio y permiten a Estados Unidos enfrentar mejor las amenazas externas.

The authors analyze China's impact on U.S.-Canadian trade. Despite Canada's having lost its historic position as the United States' first trade partner due to the hike in Chinese exports to the U.S. market, this has not affected the structure of their commercial operations. Chinese exports to the U.S. are mainly labor- and capital-intensive manufactured goods, while Canadian exports are mainly natural resources and services. In addition, the two countries have defense and security accords that facilitate trade and allow the United States to deal better with external threats., En este artículo se analiza el impacto comercial de China en el comercio entre Canadá y Estados Unidos. A pesar de que Canadá perdió su posición histórica como primer socio comercial de Estados Unidos, debido al ascenso de las exportaciones de China al mercado estadunidense, esto no ha afectado la estructura de sus intercambios comerciales. Las exportaciones chinas a Estados Unidos son principalmente manufacturas intensivas en mano de obra y capital, en tanto que las exportaciones canadienses son principalmente de recursos naturales y servicios. Además, ambos países tienen acuerdos de defensa y seguridad que agilizan el comercio y permiten a Estados Unidos enfrentar mejor las amenazas externas.

The authors analyze China's impact on U.S.-Canadian trade. Despite Canada's having lost its historic position as the United States' first trade partner due to the hike in Chinese exports to the U.S. market, this has not affected the structure of their commercial operations. Chinese exports to the U.S. are mainly labor- and capital-intensive manufactured goods, while Canadian exports are mainly natural resources and services. In addition, the two countries have defense and security accords that facilitate trade and allow the United States to deal better with external threats., En este artículo se analiza el impacto comercial de China en el comercio entre Canadá y Estados Unidos. A pesar de que Canadá perdió su posición histórica como primer socio comercial de Estados Unidos, debido al ascenso de las exportaciones de China al mercado estadunidense, esto no ha afectado la estructura de sus intercambios comerciales. Las exportaciones chinas a Estados Unidos son principalmente manufacturas intensivas en mano de obra y capital, en tanto que las exportaciones canadienses son principalmente de recursos naturales y servicios. Además, ambos países tienen acuerdos de defensa y seguridad que agilizan el comercio y permiten a Estados Unidos enfrentar mejor las amenazas externas.

The authors analyze China's impact on U.S.-Canadian trade. Despite Canada's having lost its historic position as the United States' first trade partner due to the hike in Chinese exports to the U.S. market, this has not affected the structure of their commercial operations. Chinese exports to the U.S. are mainly labor- and capital-intensive manufactured goods, while Canadian exports are mainly natural resources and services. In addition, the two countries have defense and security accords that facilitate trade and allow the United States to deal better with external threats., En este artículo se analiza el impacto comercial de China en el comercio entre Canadá y Estados Unidos. A pesar de que Canadá perdió su posición histórica como primer socio comercial de Estados Unidos, debido al ascenso de las exportaciones de China al mercado estadunidense, esto no ha afectado la estructura de sus intercambios comerciales. Las exportaciones chinas a Estados Unidos son principalmente manufacturas intensivas en mano de obra y capital, en tanto que las exportaciones canadienses son principalmente de recursos naturales y servicios. Además, ambos países tienen acuerdos de defensa y seguridad que agilizan el comercio y permiten a Estados Unidos enfrentar mejor las amenazas externas.

Ecuador is going through a substantial nutritional transition. This, coupled with the paradox that rural families that produce food are often those most affected by undernutrition, shows the ironies of ‘modern’ food systems. It also highlights the importance of rural-urban linkages around family nutrition which can help to address such contradictions. This is what we see among families living in two rural villages, San Francisco Alto and Ambuqui, in the north of Ecuador, who through various strategies have managed to achieve healthy, diversified and nutritious diets.

This brief introduces a new floating memristor emulator circuit based on second-generation current conveyors and passive elements. A mathematical model to characterize the memristor behavior was derived, showing a good accuracy among HSPICE simulations and experimental results. An analysis of the frequency behavior of the memristor is also described, showing that the frequency-dependent pinched hysteresis loop in the current-versus-voltage plane holds up to 20.2 kHz. Theoretical derivations and related results are experimentally validated through implementations from commercially available devices, and the proposed memristor emulator circuit can easily be reproducible at a low cost. Furthermore, the emulator circuit can be used as a teaching aid and for future applications with memristors, such as sensors, cellular neural networks, chaotic systems, programmable analog circuits, and nonvolatile memory devices. © 2004-2012 IEEE.

The topic of social networks has been a subject of constant analysis by the social science disciplines such as education, psychology and communication. This work aims to explore social networks from investigative productions and documentaries found in various magazines, journals and universities in Latin America. The paper explores the status of research on social networks both from the academic and professional perspective. In the first instance, are some methodological considerations the presented analysis draws. Then the work discusses research on Facebook and Twitter. The third part of the paper proposes a general mapping of research emphasis on Facebook and Twitter., El tema de las redes sociales ha sido objeto constante de análisis por parte de las disciplinas de las ciencias sociales como la educación, la psicología y la comunicación. Este trabajo en particular se propone explorarlo a partir de las producciones investigativas, reflexivas y documentales halladas en diferentes revistas, journals y centros universitarios en América Latina. El documento explora el estado de los estudios sobre redes sociales tanto desde la óptica académica como desde los intereses del campo profesional. En primera instancia, se detallan algunas consideraciones metodológicas sobre las que reposa el análisis presentado. Posteriormente, se examinan las investigaciones sobre Facebook y Twitter. La tercera parte del texto propone un mapeo general de énfasis de investigación en estos dos soportes de comunicación.

The topic of social networks has been a subject of constant analysis by the social science disciplines such as education, psychology and communication. This work aims to explore social networks from investigative productions and documentaries found in various magazines, journals and universities in Latin America. The paper explores the status of research on social networks both from the academic and professional perspective. In the first instance, are some methodological considerations the presented analysis draws. Then the work discusses research on Facebook and Twitter. The third part of the paper proposes a general mapping of research emphasis on Facebook and Twitter., El tema de las redes sociales ha sido objeto constante de análisis por parte de las disciplinas de las ciencias sociales como la educación, la psicología y la comunicación. Este trabajo en particular se propone explorarlo a partir de las producciones investigativas, reflexivas y documentales halladas en diferentes revistas, journals y centros universitarios en América Latina. El documento explora el estado de los estudios sobre redes sociales tanto desde la óptica académica como desde los intereses del campo profesional. En primera instancia, se detallan algunas consideraciones metodológicas sobre las que reposa el análisis presentado. Posteriormente, se examinan las investigaciones sobre Facebook y Twitter. La tercera parte del texto propone un mapeo general de énfasis de investigación en estos dos soportes de comunicación.

The recombinant Bm86-based tick vaccines have shown their efficacy for the control of cattle ticks, Rhipicephalus (Boophilus) microplus and R. annulatus infestations. However, cattle ticks often co-exist with multi-host ticks such as Hyalomma and Amblyomma species, thus requiring the control of multiple tick infestations for cattle and other hosts. Vaccination trials using a R. microplus recombinant Bm86-based vaccine were conducted in cattle and camels against Hyalomma dromedarii and in cattle against Amblyomma cajennense immature and adult ticks. The results showed an 89% reduction in the number of H. dromedarii nymphs engorging on vaccinated cattle, and a further 32% reduction in the weight of the surviving adult ticks. In vaccinated camels, a reduction of 27% and 31% of tick engorgement and egg mass weight, respectively was shown, while egg hatching was reduced by 39%. However, cattle vaccination with Bm86 did not have an effect on A. cajennense tick infestations. These results showed that Bm86 vaccines are effective against R. microplus and other tick species but improved vaccines containing new antigens are required to control multiple tick infestations. (C) 2012 Elsevier Ltd. All rights reserved.

The recombinant Bm86-based tick vaccines have shown their efficacy for the control of cattle ticks, Rhipicephalus (Boophilus) microplus and R. annulatus infestations. However, cattle ticks often co-exist with multi-host ticks such as Hyalomma and Amblyomma species, thus requiring the control of multiple tick infestations for cattle and other hosts. Vaccination trials using a R. microplus recombinant Bm86-based vaccine were conducted in cattle and camels against Hyalomma dromedarii and in cattle against Amblyomma cajennense immature and adult ticks. The results showed an 89% reduction in the number of H. dromedarii nymphs engorging on vaccinated cattle, and a further 32% reduction in the weight of the surviving adult ticks. In vaccinated camels, a reduction of 27% and 31% of tick engorgement and egg mass weight, respectively was shown, while egg hatching was reduced by 39%. However, cattle vaccination with Bm86 did not have an effect on A. cajennense tick infestations. These results showed that Bm86 vaccines are effective against R. microplus and other tick species but improved vaccines containing new antigens are required to control multiple tick infestations. (C) 2012 Elsevier Ltd. All rights reserved.

We report a case of a 53 years old man with acute pancreatitis, mediastinal pseudocyst and right pleural effusion who has good outcome with conservative treatment. Current diagnosis and treatment of ediastinal pseudocyst are review., Presentamos el caso de un paciente de 53 años con pancreatitis aguda,pseudoquiste mediastínico, y derrame pleural derecho que evolucionó favorablemente con tratamiento conservador. Se comentan las opciones terapéuticas y diagnóstico del pseudoquiste mediastínico

We report a case of a 53 years old man with acute pancreatitis, mediastinal pseudocyst and right pleural effusion who has good outcome with conservative treatment. Current diagnosis and treatment of ediastinal pseudocyst are review., Presentamos el caso de un paciente de 53 años con pancreatitis aguda,pseudoquiste mediastínico, y derrame pleural derecho que evolucionó favorablemente con tratamiento conservador. Se comentan las opciones terapéuticas y diagnóstico del pseudoquiste mediastínico

This work aims to know the effect of the Glomus intraradices fungus substratum inoculation on the survival, development and nutritive status of cassava, grape and olive plants during hardening. Micropropagated plants of cassava, grape and olive were transplanted individually to 2 L pots filled half of them with steamy sterilized soil and the other half with the same soil inoculated with Glomus intraradices fungus. The potted plants were placed in a culture chamber and irrigated only with tap water, maintaining field capacity. The number of dead plants, stem plus shoots growth, fresh and dry weight and nutritive status of mycorrhized and non mycorrhized plants of each species were recorded at 60 days for cassava, 30 days for grape and 180 days for olive. Presence of the fungus in the roots of each plant species was checked by staining with trypan blue. Due to the high survival percentage of the control plants, non significant differences between the survival of the control and mycorrhizal cassava and grape plants were found. On the contrary, there was a beneficial effect of mycorrhizal on olive plant surviving. With the differences due to time (days from transplanting) and plant species, in all cases mycorrhizal significantly improved aerial plant growth and biomass production. Mycorrhizal only affected positively the relative content of P in both cassava and olive plants, and Fe in olive. Considering the bigger biomass of the mycorrhized plants the total amount of each nutrient was higher in these plants. All the mycorrhizal plants responded positively to trypan blue treatment.

This study reports the effectiveness of an arbuscular mycorrhizal (AM) fungus Glomus intraradices on three clones (SOM-1, 05 and 50) of cassava (Manihot esculenta). Arbuscular mycorrhizal inoculation increased plant resistance to transplant stress from “in vitro” to “ex vitro” conditions and plant biomass (shoot and root) production was greatly enhanced by AM-colonization. The magnitude of AM growth stimulation over control clones was: 861% (SOM-1), 1042% (05) and 854% (50). Arbuscular mycorrhizal colonized cassava plants increased cassavawater uptake in terms of percentage, 62% in clone SOM-1, 24% in clone 05, and 157% in clone 50. The highest effect of AM-colonization on water content in root of clone 50 was correlated with the greatest increment in leaf tissue production (1218% over control) and with the maximum shoot/root ratio determined. The biomass distribution between shoot and root was changed by AMsymbiosis and such effect varied for each clone that may be caused by mycorrhizal changes in macro/micro-nutrients translocation/compartimentation. Cassava dependence on AM symbiosis was greatest in clone SOM-1 since AM-colonization provided the highest stem (weight, length, and diameters), leaf (weight and number), bud number, and root weight. These results lead to practical applications because AM inoculation is crucial for improving cassava yield (shoot and root) and nutrition irrespective of the clone involved. Thus, importance of AM symbiosis in micropropagated cassava clones is of great practical interest in agriculture and allows the selection of the most suitable clone for dry environments due to the particular effect on root water content that improves drought adaptation.