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En este vídeo se contrastan las formas iconográficas que la tradición de la historia del arte ha tratado en las representaciones de David y Goliath según la el relato bíblico.

En este vídeo se contrastan las formas iconográficas que la tradición de la historia del arte ha tratado en las representaciones de Eros y Psique según la mitografía.

Tuber aestivum is associated with a wide range of tree species and is the most widespread edible truffle. Its capability of colonizing many different areas along with a long reaping period, increased in the last decades scientific studies and commercial interest. A number of large- and fine-scale population genetics studies have been conducted to explore its genetic diversity and genetic structure. Recent investigations based on ITS sequence analyses revealed a strong phylogenetic pattern and a higher level of genetic diversity in Turkish and southern European populations than in northern European populations, suggesting that Turkey and southern Europe may have acted as glacial refugia for this species. Despite these findings, the southernmost distributional range of the species is not yet fully explored. With the aim of evaluating other potential diversity hotspots in this study we expand previous investigation, extending the sampling to other southernmost natural T. aestivum areas, such as Moroccan mountainous regions (Middle Atlas), Serbia and several Spanish regions. The ongoing analyses based on haplotypes alignment of the ITS region of the rDNA, reveal as preliminary result a pronounced genetic variability among Moroccan T. aestivum populations, suggesting a possible phylogeographic differentiation also in these new areas of investigation. Additional analyses are underway to better trace natural populations of T. aestivum according to their geographic origin. These aims could be critical both for truffle industry interest in selecting well-adapted inoculum for the production of mycorrhizal seedlings or traceability of truffles provenance, and for the establishment of programs devoted to biodiversity conservation.

[EN] A diversity-oriented approach to enantiomerically pure densely substituted pyrazoles, ¿-aryl-¿-pyrazolylatrolactic acid and ¿-aryl-¿-pyrazolylacetophenones has been developed. The approach utilises the conjugated addition of the lithium enolate of the (2S,5S)-cis-1,3-dioxolan-4-one derived from optically active (S)-mandelic acid and pivalaldehyde to several 2-arylidene-1,3-diketones, which proceeds readily to give the corresponding Michael adducts in good yields and diastereoselectivities. The cyclocondensation of the 1,3-diketone moieties present in Michael adducts with several hydrazines leads to enantiomerically pure densely substituted pyrazoles. Subsequent basic hydrolysis of the dioxolanone moiety present in these products leads to enantiomerically pure ¿-aryl-¿-pyrazolylatrolactic acids. Finally, oxidative decarboxylation of these using oxygen, pivalaldehyde and the Co(III)¿Me2opba complex as catalyst gives ¿-aryl-¿-pyrazolylacetophenones. In this approach four points of diversity are introduced, one of them is the configuration of the (S)-mandelic acid, which acts as an umpoled chiral equivalent of the benzoyl anion.

[EN] A diversity-oriented approach to enantiomerically pure densely substituted pyrazoles, ¿-aryl-¿-pyrazolylatrolactic acid and ¿-aryl-¿-pyrazolylacetophenones has been developed. The approach utilises the conjugated addition of the lithium enolate of the (2S,5S)-cis-1,3-dioxolan-4-one derived from optically active (S)-mandelic acid and pivalaldehyde to several 2-arylidene-1,3-diketones, which proceeds readily to give the corresponding Michael adducts in good yields and diastereoselectivities. The cyclocondensation of the 1,3-diketone moieties present in Michael adducts with several hydrazines leads to enantiomerically pure densely substituted pyrazoles. Subsequent basic hydrolysis of the dioxolanone moiety present in these products leads to enantiomerically pure ¿-aryl-¿-pyrazolylatrolactic acids. Finally, oxidative decarboxylation of these using oxygen, pivalaldehyde and the Co(III)¿Me2opba complex as catalyst gives ¿-aryl-¿-pyrazolylacetophenones. In this approach four points of diversity are introduced, one of them is the configuration of the (S)-mandelic acid, which acts as an umpoled chiral equivalent of the benzoyl anion.