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1. Fit for CCUS: amending the EU legal framework in order to foster carbon capture technologies & reach net zero

Author: Mannetje , I.S. 't, Mannetje , I.S. 't, Mannetje , I.S. 't, and Mannetje , I.S. 't
Abstract: The full text of this thesis is not available due to privacy or embargo reasons.
Published: 2023

2. Let them flourish:enhancing higher education students’ well-being

Author: 't Mannetje, Jolise and 't Mannetje, Jolise
Abstract: Student well-being in higher education is receiving increasing attention. This is a good development, partly because well-being is related to being able to study successfully. Using the Job Demands-Resources model as a theoretical foundation, this dissertation investigates the well-being and promotion of well-being of students in general and honours students in particular, aiming to answer the research question: What personal resources promote higher education students’ well-being and how can these personal resources be enhanced by education? Exploratory interviews with honours students investigated which personal resources they believe are important for achieving success. Path analysis was then used to investigate which personal resources are most strongly associated with levels of engagement and stress of students. The systematic review that followed described, from 123 included studies, the characteristics of interventions to promote well-being, the underlying theories, the effects of interventions and possible factors influencing effectiveness. Finally, educational design principles are formulated for designing interventions to (further) develop four personal resources of honours students; self-efficacy, optimism, inquiry mindedness, and self-regulation. It is recommended that, based on the findings, further educational design research is conducted to both design effective interventions to develop students' personal resources and further develop the associated theory. In this way, increasingly evidence-based work can be done to promote student well-being.
Published: 2023

3. Exploring the boundaries of endovascular aneurysm repair: studying an all-comers population

Author: 't Mannetje, Yannick Willem, 't Mannetje, Yannick Willem, 't Mannetje, Yannick Willem, and 't Mannetje, Yannick Willem
Abstract: An abdominal aortic aneurysm can be treated endovascularly since the early 1990s. In the endovascular technique, a stent is placed through the groin, which is less invasive than the open technique. An important limitation is that ruptured and complex aneurysms are less suitable and more long-term complications are seen. With the help of registration studies, this thesis investigated how stents function at the extremes of the manufacturers' instructions for use. The thesis shows that in the case of ruptured aneurysms, the technical results are good. Additionally, it is shown that in complex aneurysms the short-term number of complications is not unacceptable, despite the challenging anatomy. The long-term results will have to be determined in the future. The above results can contribute to determining the optimal treatment strategy of ruptured and complex aneurysms.
Published: 2020

4. Occupational exposures to pesticides and other chemicals: a New Zealand motor neuron disease case-control study

Author: Chen, Grace Xia, Douwes, J, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, Glass, Bill, McLean, David J, 't Mannetje, Andrea Martine, Chen, Grace Xia, Douwes, J, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, Glass, Bill, McLean, David J, and 't Mannetje, Andrea Martine
Abstract: Objectives: To assess associations between occupational exposures to pesticides and other chemicals and motor neuron disease (MND). Methods: A population-based case-control study that included 319 MND cases (64% male/36% female) recruited through the New Zealand MND Association complemented with hospital discharge data, and 604 controls identified from the Electoral Roll. For each job held, a questionnaire collected information on 11 exposure categories (dust, fibres, tobacco smoke, fumes, gas, fumigants, oils/solvents, acids/alkalis, pesticides, other chemicals and animals/animal products). ORs were estimated using logistic regression adjusting for age, sex, ethnicity, socioeconomic status, education, smoking, alcohol consumption, physical activities, head/spine injury and other occupational exposures. Results: Two exposure categories were associated with increased MND risks: pesticides (OR 1.70, 95% CI 1.17 to 2.48) and fumigants (OR 3.98, 95% CI 1.81 to 8.76), with risks increasing with longer exposure duration (p<0.01). Associations were also observed for: methyl bromide (OR 5.28, 95% CI 1.63 to 17.15), organochlorine insecticides (OR 3.28, 95% CI 1.18 to 9.07), organophosphate insecticides (OR 3.11, 95% CI 1.40 to 6.94), pyrethroid insecticides (OR 6.38, 95% CI 1.13 to 35.96), inorganic (copper) fungicides (OR 4.66, 95% CI 1.53 to 14.19), petrol/diesel fuel (OR 2.24, 95% CI 1.27 to 3.93) and unspecified solvents (OR 1.91, 95% CI 1.22 to 2.99). In women, exposure to textile fibres (OR 2.49, 95% CI 1.13 to 5.50), disinfectants (OR 9.66, 95% CI 1.29 to 72.44) and cleaning products (OR 3.53, 95% CI 1.64 to 7.59) were also associated with MND; this was not observed in men (OR 0.80, 95% CI 0.44 to 1.48; OR 0.72, 95% CI 0.29 to 1.84; OR 0.57, 95% CI 0.21 to 1.56, respectively). Conclusions: This study adds to the evidence that pesticides, especially insecticides, fungicides, and fumigants, are risk factors for MND.
Published: 2022

5. Wireless phone use in childhood and adolescence and neuroepithelial brain tumours: Results from the international MOBI-Kids study

Author: Castaño-Vinyals, G, Sadetzki, S, Vermeulen, R, Momoli, F, Kundi, M, Merletti, F, Maslanyj, M, Calderon, C, Wiart, J, Lee, A-K, Taki, M, Sim, M, Armstrong, B, Benke, G, Schattner, R, Hutter, H-P, Krewski, D, Mohipp, C, Ritvo, P, Spinelli, J, Lacour, B, Remen, T, Radon, K, Weinmann, T, Petridou, E Th, Moschovi, M, Pourtsidis, A, Oikonomou, K, Kanavidis, P, Bouka, E, Dikshit, R, Nagrani, R, Chetrit, A, Bruchim, R, Maule, M, Migliore, E, Filippini, G, Miligi, L, Mattioli, S, Kojimahara, N, Yamaguchi, N, Ha, M, Choi, K, Kromhout, H, Goedhart, G, 't Mannetje, A, Eng, A, Langer, C E, Alguacil, J, Aragonés, N, Morales-Suárez-Varela, M, Badia, F, Albert, A, Carretero, G, Cardis, E, Castaño-Vinyals, G, Sadetzki, S, Vermeulen, R, Momoli, F, Kundi, M, Merletti, F, Maslanyj, M, Calderon, C, Wiart, J, Lee, A-K, Taki, M, Sim, M, Armstrong, B, Benke, G, Schattner, R, Hutter, H-P, Krewski, D, Mohipp, C, Ritvo, P, Spinelli, J, Lacour, B, Remen, T, Radon, K, Weinmann, T, Petridou, E Th, Moschovi, M, Pourtsidis, A, Oikonomou, K, Kanavidis, P, Bouka, E, Dikshit, R, Nagrani, R, Chetrit, A, Bruchim, R, Maule, M, Migliore, E, Filippini, G, Miligi, L, Mattioli, S, Kojimahara, N, Yamaguchi, N, Ha, M, Choi, K, Kromhout, H, Goedhart, G, 't Mannetje, A, Eng, A, Langer, C E, Alguacil, J, Aragonés, N, Morales-Suárez-Varela, M, Badia, F, Albert, A, Carretero, G, and Cardis, E
Abstract: In recent decades, the possibility that use of mobile communicating devices, particularly wireless (mobile and cordless) phones, may increase brain tumour risk, has been a concern, particularly given the considerable increase in their use by young people. MOBI-Kids, a 14-country (Australia, Austria, Canada, France, Germany, Greece, India, Israel, Italy, Japan, Korea, the Netherlands, New Zealand, Spain) case-control study, was conducted to evaluate whether wireless phone use (and particularly resulting exposure to radiofrequency (RF) and extremely low frequency (ELF) electromagnetic fields (EMF)) increases risk of brain tumours in young people. Between 2010 and 2015, the study recruited 899 people with brain tumours aged 10 to 24 years old and 1,910 controls (operated for appendicitis) matched to the cases on date of diagnosis, study region and age. Participation rates were 72% for cases and 54% for controls. The mean ages of cases and controls were 16.5 and 16.6 years, respectively; 57% were males. The vast majority of study participants were wireless phones users, even in the youngest age group, and the study included substantial numbers of long-term (over 10 years) users: 22% overall, 51% in the 20-24-year-olds. Most tumours were of the neuroepithelial type (NBT; n = 671), mainly glioma. The odds ratios (OR) of NBT appeared to decrease with increasing time since start of use of wireless phones, cumulative number of calls and cumulative call time, particularly in the 15-19 years old age group. A decreasing trend in ORs was also observed with increasing estimated cumulative RF specific energy and ELF induced current density at the location of the tumour. Further analyses suggest that the large number of ORs below 1 in this study is unlikely to represent an unknown causal preventive effect of mobile phone exposure: they can be at least partially explained by differential recall by proxies and prodromal symptoms affecting phone use before diagnosis of the cases. W
Published: 2022

6. Occupational exposures to pesticides and other chemicals: a New Zealand motor neuron disease case-control study

Author: IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Chen, Grace Xia, Douwes, J, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, Glass, Bill, McLean, David J, 't Mannetje, Andrea Martine, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Chen, Grace Xia, Douwes, J, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, Glass, Bill, McLean, David J, and 't Mannetje, Andrea Martine
Published: 2022

7. Wireless phone use in childhood and adolescence and neuroepithelial brain tumours: Results from the international MOBI-Kids study

Author: IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Castaño-Vinyals, G, Sadetzki, S, Vermeulen, R, Momoli, F, Kundi, M, Merletti, F, Maslanyj, M, Calderon, C, Wiart, J, Lee, A-K, Taki, M, Sim, M, Armstrong, B, Benke, G, Schattner, R, Hutter, H-P, Krewski, D, Mohipp, C, Ritvo, P, Spinelli, J, Lacour, B, Remen, T, Radon, K, Weinmann, T, Petridou, E Th, Moschovi, M, Pourtsidis, A, Oikonomou, K, Kanavidis, P, Bouka, E, Dikshit, R, Nagrani, R, Chetrit, A, Bruchim, R, Maule, M, Migliore, E, Filippini, G, Miligi, L, Mattioli, S, Kojimahara, N, Yamaguchi, N, Ha, M, Choi, K, Kromhout, H, Goedhart, G, 't Mannetje, A, Eng, A, Langer, C E, Alguacil, J, Aragonés, N, Morales-Suárez-Varela, M, Badia, F, Albert, A, Carretero, G, Cardis, E, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Castaño-Vinyals, G, Sadetzki, S, Vermeulen, R, Momoli, F, Kundi, M, Merletti, F, Maslanyj, M, Calderon, C, Wiart, J, Lee, A-K, Taki, M, Sim, M, Armstrong, B, Benke, G, Schattner, R, Hutter, H-P, Krewski, D, Mohipp, C, Ritvo, P, Spinelli, J, Lacour, B, Remen, T, Radon, K, Weinmann, T, Petridou, E Th, Moschovi, M, Pourtsidis, A, Oikonomou, K, Kanavidis, P, Bouka, E, Dikshit, R, Nagrani, R, Chetrit, A, Bruchim, R, Maule, M, Migliore, E, Filippini, G, Miligi, L, Mattioli, S, Kojimahara, N, Yamaguchi, N, Ha, M, Choi, K, Kromhout, H, Goedhart, G, 't Mannetje, A, Eng, A, Langer, C E, Alguacil, J, Aragonés, N, Morales-Suárez-Varela, M, Badia, F, Albert, A, Carretero, G, and Cardis, E
Published: 2022

8. Occupational exposures to pesticides and other chemicals: a New Zealand motor neuron disease case-control study

Author: IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Chen, Grace Xia, Douwes, J, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, Glass, Bill, McLean, David J, 't Mannetje, Andrea Martine, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Chen, Grace Xia, Douwes, J, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, Glass, Bill, McLean, David J, and 't Mannetje, Andrea Martine
Published: 2022

9. Wireless phone use in childhood and adolescence and neuroepithelial brain tumours: Results from the international MOBI-Kids study

Author: IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Castaño-Vinyals, G, Sadetzki, S, Vermeulen, R, Momoli, F, Kundi, M, Merletti, F, Maslanyj, M, Calderon, C, Wiart, J, Lee, A-K, Taki, M, Sim, M, Armstrong, B, Benke, G, Schattner, R, Hutter, H-P, Krewski, D, Mohipp, C, Ritvo, P, Spinelli, J, Lacour, B, Remen, T, Radon, K, Weinmann, T, Petridou, E Th, Moschovi, M, Pourtsidis, A, Oikonomou, K, Kanavidis, P, Bouka, E, Dikshit, R, Nagrani, R, Chetrit, A, Bruchim, R, Maule, M, Migliore, E, Filippini, G, Miligi, L, Mattioli, S, Kojimahara, N, Yamaguchi, N, Ha, M, Choi, K, Kromhout, H, Goedhart, G, 't Mannetje, A, Eng, A, Langer, C E, Alguacil, J, Aragonés, N, Morales-Suárez-Varela, M, Badia, F, Albert, A, Carretero, G, Cardis, E, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Castaño-Vinyals, G, Sadetzki, S, Vermeulen, R, Momoli, F, Kundi, M, Merletti, F, Maslanyj, M, Calderon, C, Wiart, J, Lee, A-K, Taki, M, Sim, M, Armstrong, B, Benke, G, Schattner, R, Hutter, H-P, Krewski, D, Mohipp, C, Ritvo, P, Spinelli, J, Lacour, B, Remen, T, Radon, K, Weinmann, T, Petridou, E Th, Moschovi, M, Pourtsidis, A, Oikonomou, K, Kanavidis, P, Bouka, E, Dikshit, R, Nagrani, R, Chetrit, A, Bruchim, R, Maule, M, Migliore, E, Filippini, G, Miligi, L, Mattioli, S, Kojimahara, N, Yamaguchi, N, Ha, M, Choi, K, Kromhout, H, Goedhart, G, 't Mannetje, A, Eng, A, Langer, C E, Alguacil, J, Aragonés, N, Morales-Suárez-Varela, M, Badia, F, Albert, A, Carretero, G, and Cardis, E
Published: 2022

10. Occupational/environmental and lifestyle risk factors for motor neurone disease in New Zealand : a thesis with publications presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Public Health (epidemiology) at Massey University, Wellington, New Zealand

Author: 't Mannetje, Andrea, Chen, Grace Xia, 't Mannetje, Andrea, and Chen, Grace Xia
Abstract: Motor Neurone Diseases (MND) are a group of progressive, irreversible, and terminal neurodegenerative diseases, with death usually resulting about three years after first symptoms of weakness. No cure is available. Whilst the aetiology of MND is largely unknown, some occupations, occupational exposures, and lifestyle factors have been associated with elevated risks, but evidence has been mixed. This thesis describes a case-control study that assessed associations with MND for a range of potentially modifiable risk factors, including specific occupations; occupational exposures (extremely low frequency-magnetic fields (ELF-MF), electric shocks, and a range of chemicals including pesticides); physical and emotional trauma; and leisure sports. A total of 321 cases and 605 population controls participated in the study. Elevated risks for MND were observed for several horticultural occupations, including field crop and vegetable growers, fruit growers, gardeners and nursery growers, crop and livestock producers. Employment as a builder, electrician, caregiver, forecourt attendant, plant and machine operator and assembler, and telecommunications technician was also positively associated with MND. Having ever worked in an occupation with potential for electric shocks was positively associated with MND, but no association was observed for occupational exposure to ELF-MF. Occupational exposure to pesticides, in particular insecticides, fungicides, and fumigants was associated with MND, with longer exposure duration associated with higher risk. Elevated odds for MND were also found for exposure to petrol/diesel fuel, unspecified solvents, disinfectants, and cleaning products. Having had multiple head injuries with concussion was associated with increased odds of MND; spine injury was not associated with MND. Playing sports throughout childhood and adulthood increased the risk of MND compared to never engaging in sports. Playing football (soccer) for >12 years was also positiv
Published: 2022

11. Occupational exposures to pesticides and other chemicals: a New Zealand motor neuron disease case-control study

Author: IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Chen, Grace Xia, Douwes, J, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, Glass, Bill, McLean, David J, 't Mannetje, Andrea Martine, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Chen, Grace Xia, Douwes, J, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, Glass, Bill, McLean, David J, and 't Mannetje, Andrea Martine
Published: 2022

12. Wireless phone use in childhood and adolescence and neuroepithelial brain tumours: Results from the international MOBI-Kids study

Author: IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Castaño-Vinyals, G, Sadetzki, S, Vermeulen, R, Momoli, F, Kundi, M, Merletti, F, Maslanyj, M, Calderon, C, Wiart, J, Lee, A-K, Taki, M, Sim, M, Armstrong, B, Benke, G, Schattner, R, Hutter, H-P, Krewski, D, Mohipp, C, Ritvo, P, Spinelli, J, Lacour, B, Remen, T, Radon, K, Weinmann, T, Petridou, E Th, Moschovi, M, Pourtsidis, A, Oikonomou, K, Kanavidis, P, Bouka, E, Dikshit, R, Nagrani, R, Chetrit, A, Bruchim, R, Maule, M, Migliore, E, Filippini, G, Miligi, L, Mattioli, S, Kojimahara, N, Yamaguchi, N, Ha, M, Choi, K, Kromhout, H, Goedhart, G, 't Mannetje, A, Eng, A, Langer, C E, Alguacil, J, Aragonés, N, Morales-Suárez-Varela, M, Badia, F, Albert, A, Carretero, G, Cardis, E, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Castaño-Vinyals, G, Sadetzki, S, Vermeulen, R, Momoli, F, Kundi, M, Merletti, F, Maslanyj, M, Calderon, C, Wiart, J, Lee, A-K, Taki, M, Sim, M, Armstrong, B, Benke, G, Schattner, R, Hutter, H-P, Krewski, D, Mohipp, C, Ritvo, P, Spinelli, J, Lacour, B, Remen, T, Radon, K, Weinmann, T, Petridou, E Th, Moschovi, M, Pourtsidis, A, Oikonomou, K, Kanavidis, P, Bouka, E, Dikshit, R, Nagrani, R, Chetrit, A, Bruchim, R, Maule, M, Migliore, E, Filippini, G, Miligi, L, Mattioli, S, Kojimahara, N, Yamaguchi, N, Ha, M, Choi, K, Kromhout, H, Goedhart, G, 't Mannetje, A, Eng, A, Langer, C E, Alguacil, J, Aragonés, N, Morales-Suárez-Varela, M, Badia, F, Albert, A, Carretero, G, and Cardis, E
Published: 2022

13. Occupational exposures to pesticides and other chemicals: a New Zealand motor neuron disease case-control study

Author: MS CGO, Neurologen, Projectafdeling ALS, Brain, Regenerative Medicine and Stem Cells, Chen, Grace Xia, Douwes, J, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, Glass, Bill, McLean, David J, 't Mannetje, Andrea Martine, MS CGO, Neurologen, Projectafdeling ALS, Brain, Regenerative Medicine and Stem Cells, Chen, Grace Xia, Douwes, J, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, Glass, Bill, McLean, David J, and 't Mannetje, Andrea Martine
Published: 2022

14. Sports and trauma as risk factors for Motor Neurone Disease: New Zealand case-control study

Author: Neurologen, Projectafdeling ALS, Brain, Regenerative Medicine and Stem Cells, Chen, Grace Xia, Douwes, Jeroen, van den Berg, Leonard H, Glass, Bill, McLean, David, 't Mannetje, Andrea Martine, Neurologen, Projectafdeling ALS, Brain, Regenerative Medicine and Stem Cells, Chen, Grace Xia, Douwes, Jeroen, van den Berg, Leonard H, Glass, Bill, McLean, David, and 't Mannetje, Andrea Martine
Published: 2022

15. Lung cancer risk in painters: results from the SYNERGY pooled case–control study consortium

Author: Guha, Neela, Bouaoun, Liacine, Kromhout, Hans, Vermeulen, Roel, Brüning, Thomas, Behrens, Thomas, Peters, Susan, Luzon, Véronique, Siemiatycki, Jack, Xu, Mengting, Kendzia, Benjamin, Guenel, Pascal, Luce, Danièle, Karrasch, Stefan, Wichmann, Heinz-Erich, Consonni, Dario, Landi, Maria Teresa, Caporaso, Neil E, Gustavsson, Per, Plato, Nils, Merletti, Franco, Mirabelli, Dario, Richiardi, Lorenzo, Jöckel, Karl-Heinz, Ahrens, Wolfgang, Pohlabeln, Hermann, TSE, Lap Ah, Yu, Ignatius Tak-Sun, Tardón, Adonina, Boffetta, Paolo, Zaridze, David, 't Mannetje, Andrea, Pearce, Neil, Davies, Michael P A, Lissowska, Jolanta, Świątkowska, Beata, McLaughlin, John, Demers, Paul A, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Pándics, Tamás, Fabianova, Eleonora, Mates, Dana, Forastiere, Francesco, Bueno-de-Mesquita, Bas, Schüz, Joachim, Straif, Kurt, Olsson, Ann, Guha, Neela, Bouaoun, Liacine, Kromhout, Hans, Vermeulen, Roel, Brüning, Thomas, Behrens, Thomas, Peters, Susan, Luzon, Véronique, Siemiatycki, Jack, Xu, Mengting, Kendzia, Benjamin, Guenel, Pascal, Luce, Danièle, Karrasch, Stefan, Wichmann, Heinz-Erich, Consonni, Dario, Landi, Maria Teresa, Caporaso, Neil E, Gustavsson, Per, Plato, Nils, Merletti, Franco, Mirabelli, Dario, Richiardi, Lorenzo, Jöckel, Karl-Heinz, Ahrens, Wolfgang, Pohlabeln, Hermann, TSE, Lap Ah, Yu, Ignatius Tak-Sun, Tardón, Adonina, Boffetta, Paolo, Zaridze, David, 't Mannetje, Andrea, Pearce, Neil, Davies, Michael P A, Lissowska, Jolanta, Świątkowska, Beata, McLaughlin, John, Demers, Paul A, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Pándics, Tamás, Fabianova, Eleonora, Mates, Dana, Forastiere, Francesco, Bueno-de-Mesquita, Bas, Schüz, Joachim, Straif, Kurt, and Olsson, Ann
Abstract: Objectives We evaluated the risk of lung cancer associated with ever working as a painter, duration of employment and type of painter by histological subtype as well as joint effects with smoking, within the SYNERGY project. Methods Data were pooled from 16 participating case–control studies conducted internationally. Detailed individual occupational and smoking histories were available for 19 369 lung cancer cases (684 ever employed as painters) and 23 674 age-matched and sex-matched controls (532 painters). Multivariable unconditional logistic regression models were adjusted for age, sex, centre, cigarette pack-years, time-since-smoking cessation and lifetime work in other jobs that entailed exposure to lung carcinogens. Results Ever having worked as a painter was associated with an increased risk of lung cancer in men (OR 1.30; 95% CI 1.13 to 1.50). The association was strongest for construction and repair painters and the risk was elevated for all histological subtypes, although more evident for small cell and squamous cell lung cancer than for adenocarcinoma and large cell carcinoma. There was evidence of interaction on the additive scale between smoking and employment as a painter (relative excess risk due to interaction >0). Conclusions Our results by type/industry of painter may aid future identification of causative agents or exposure scenarios to develop evidence-based practices for reducing harmful exposures in painters.
Published: 2021

16. Occupational Exposure to Electric Shocks and Extremely Low-Frequency Magnetic Fields and Motor Neurone Disease

Author: Chen, Grace X, Mannetje, Andrea't, Douwes, Jeroen, Berg, Leonard H, Pearce, Neil, Kromhout, Hans, Glass, Bill, Brewer, Naomi, McLean, Dave J, Chen, Grace X, Mannetje, Andrea't, Douwes, Jeroen, Berg, Leonard H, Pearce, Neil, Kromhout, Hans, Glass, Bill, Brewer, Naomi, and McLean, Dave J
Abstract: In a New Zealand population-based case-control study we assessed associations with occupational exposure to electric shocks, extremely low-frequency magnetic fields (ELF-MF) and motor neurone disease using job-exposure matrices to assess exposure. Participants were recruited between 2013 and 2016. Associations with ever/never, duration, and cumulative exposure were assessed using logistic regression adjusted for age, sex, ethnicity, socioeconomic status, education, smoking, alcohol consumption, sports, head or spine injury and solvents, and mutually adjusted for the other exposure. All analyses were repeated stratified by sex. An elevated risk was observed for having ever worked in a job with potential for electric shocks (odds ratio (OR)=1.35, 95% confidence interval (CI): 0.98, 1.86), with the strongest association for the highest level of exposure (OR=2.01, 95%CI: 1.31, 3.09). Analysis by duration suggested a non-linear association: risk was increased for both short-duration (<3 years) (OR= 4.69, 95%CI: 2.25, 9.77) and long-duration in a job with high level of electric shock exposure (>24 years; OR=1.88; 95%CI: 1.05, 3.36), with less pronounced associations for intermediate durations. No association with ELF-MF was found. Our findings provide support for an association between occupational exposure to electric shocks and motor neurone disease but did not show associations with exposure to work-related ELF-MF.
Published: 2021

17. Personal resources conducive to educational success: high achieving students’ perspectives

Author: 't Mannetje, J., Heijne-Penninga, Marjolein, Mastenbroek, N., Wolfensberger, Marca, Jaarsma, D., 't Mannetje, J., Heijne-Penninga, Marjolein, Mastenbroek, N., Wolfensberger, Marca, and Jaarsma, D.
Abstract: This study was explorative and aimed at in-depth understanding of personal resources students use to reach success, in the demanding context of honours education. Becoming successful in higher education demands a lot from students. Considering the Job Demands-Resources model it is expected that personal resources help students succeed. We explore which personal resources benefit students’ performance in demanding contexts of honours education. Using a questionnaire and semi-structured interviews, we asked thirteen honours students of three institutions which personal resources had helped them to achieve success. Results suggest that honours students use different personal resources. Most frequently mentioned resources could be grouped around five themes: self-directiveness, inquiry-mindedness, perseverance, social involvement and motivation. Especially resources in the themes self-directiveness, inquiry-mindedness and perseverance were perceived as important facilitators for educational success. The outcomes may inform interventions to help students develop personal resources needed to handle high educational demands. Further research is needed to identify the most effective interventions.
Published: 2021

18. Lung cancer risk in painters: results from the SYNERGY pooled case–control study consortium

Author: IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Guha, Neela, Bouaoun, Liacine, Kromhout, Hans, Vermeulen, Roel, Brüning, Thomas, Behrens, Thomas, Peters, Susan, Luzon, Véronique, Siemiatycki, Jack, Xu, Mengting, Kendzia, Benjamin, Guenel, Pascal, Luce, Danièle, Karrasch, Stefan, Wichmann, Heinz-Erich, Consonni, Dario, Landi, Maria Teresa, Caporaso, Neil E, Gustavsson, Per, Plato, Nils, Merletti, Franco, Mirabelli, Dario, Richiardi, Lorenzo, Jöckel, Karl-Heinz, Ahrens, Wolfgang, Pohlabeln, Hermann, TSE, Lap Ah, Yu, Ignatius Tak-Sun, Tardón, Adonina, Boffetta, Paolo, Zaridze, David, 't Mannetje, Andrea, Pearce, Neil, Davies, Michael P A, Lissowska, Jolanta, Świątkowska, Beata, McLaughlin, John, Demers, Paul A, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Pándics, Tamás, Fabianova, Eleonora, Mates, Dana, Forastiere, Francesco, Bueno-de-Mesquita, Bas, Schüz, Joachim, Straif, Kurt, Olsson, Ann, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Guha, Neela, Bouaoun, Liacine, Kromhout, Hans, Vermeulen, Roel, Brüning, Thomas, Behrens, Thomas, Peters, Susan, Luzon, Véronique, Siemiatycki, Jack, Xu, Mengting, Kendzia, Benjamin, Guenel, Pascal, Luce, Danièle, Karrasch, Stefan, Wichmann, Heinz-Erich, Consonni, Dario, Landi, Maria Teresa, Caporaso, Neil E, Gustavsson, Per, Plato, Nils, Merletti, Franco, Mirabelli, Dario, Richiardi, Lorenzo, Jöckel, Karl-Heinz, Ahrens, Wolfgang, Pohlabeln, Hermann, TSE, Lap Ah, Yu, Ignatius Tak-Sun, Tardón, Adonina, Boffetta, Paolo, Zaridze, David, 't Mannetje, Andrea, Pearce, Neil, Davies, Michael P A, Lissowska, Jolanta, Świątkowska, Beata, McLaughlin, John, Demers, Paul A, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Pándics, Tamás, Fabianova, Eleonora, Mates, Dana, Forastiere, Francesco, Bueno-de-Mesquita, Bas, Schüz, Joachim, Straif, Kurt, and Olsson, Ann
Published: 2021

19. Occupational Exposure to Electric Shocks and Extremely Low-Frequency Magnetic Fields and Motor Neurone Disease

Author: IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Chen, Grace X, Mannetje, Andrea't, Douwes, Jeroen, Berg, Leonard H, Pearce, Neil, Kromhout, Hans, Glass, Bill, Brewer, Naomi, McLean, Dave J, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Chen, Grace X, Mannetje, Andrea't, Douwes, Jeroen, Berg, Leonard H, Pearce, Neil, Kromhout, Hans, Glass, Bill, Brewer, Naomi, and McLean, Dave J
Published: 2021

20. Clinical presentation of young people (10-24 years old) with brain tumors: results from the international MOBI-Kids study

Author: Zumel-Marne, Angela, Kundi, Michael, Castaño-Vinyals, Gemma, Alguacil, Juan, Petridou, Eleni Th, Georgakis, Marios K, Morales-Suárez-Varela, Maria, Sadetzki, Siegal, Piro, Sara, Nagrani, Rajini, Filippini, Graziella, Hutter, Hans-Peter, Dikshit, Rajesh, Woehrer, Adelheid, Maule, Milena, Weinmann, Tobias, Krewski, Daniel, T Mannetje, Andrea, Momoli, Franco, Lacour, Brigitte, Mattioli, Stefano, Spinelli, John J, Ritvo, Paul, Remen, Thomas, Kojimahara, Noriko, Eng, Amanda, Thurston, Angela, Lim, Hyungryul, Ha, Mina, Yamaguchi, Naohito, Mohipp, Charmaine, Bouka, Evdoxia, Eastman, Chelsea, Vermeulen, Roel, Kromhout, Hans, Cardis, Elisabeth, Zumel-Marne, Angela, Kundi, Michael, Castaño-Vinyals, Gemma, Alguacil, Juan, Petridou, Eleni Th, Georgakis, Marios K, Morales-Suárez-Varela, Maria, Sadetzki, Siegal, Piro, Sara, Nagrani, Rajini, Filippini, Graziella, Hutter, Hans-Peter, Dikshit, Rajesh, Woehrer, Adelheid, Maule, Milena, Weinmann, Tobias, Krewski, Daniel, T Mannetje, Andrea, Momoli, Franco, Lacour, Brigitte, Mattioli, Stefano, Spinelli, John J, Ritvo, Paul, Remen, Thomas, Kojimahara, Noriko, Eng, Amanda, Thurston, Angela, Lim, Hyungryul, Ha, Mina, Yamaguchi, Naohito, Mohipp, Charmaine, Bouka, Evdoxia, Eastman, Chelsea, Vermeulen, Roel, Kromhout, Hans, and Cardis, Elisabeth
Abstract: INTRODUCTION: We used data from MOBI-Kids, a 14-country international collaborative case-control study of brain tumors (BTs), to study clinical characteristics of the tumors in older children (10 years or older), adolescents and young adults (up to the age of 24).METHODS: Information from clinical records was obtained for 899 BT cases, including signs and symptoms, symptom onset, diagnosis date, tumor type and location.RESULTS: Overall, 64% of all tumors were low-grade, 76% were neuroepithelial tumors and 62% gliomas. There were more males than females among neuroepithelial and embryonal tumor cases, but more females with meningeal tumors. The most frequent locations were cerebellum (22%) and frontal (16%) lobe. The most frequent symptom was headaches (60%), overall, as well as for gliomas, embryonal and 'non-neuroepithelial' tumors; it was convulsions/seizures for neuroepithelial tumors other than glioma, and visual signs and symptoms for meningiomas. A cluster analysis showed that headaches and nausea/vomiting was the only combination of symptoms that exceeded a cutoff of 50%, with a joint occurrence of 67%. Overall, the median time from first symptom to diagnosis was 1.42 months (IQR 0.53-4.80); it exceeded 1 year in 12% of cases, though no particular symptom was associated with exceptionally long or short delays.CONCLUSIONS: This is the largest clinical epidemiology study of BT in young people conducted so far. Many signs and symptoms were identified, dominated by headaches and nausea/vomiting. Diagnosis was generally rapid but in 12% diagnostic delay exceeded 1 year with none of the symptoms been associated with a distinctly long time until diagnosis.
Published: 2020

21. Clinical presentation of young people (10-24 years old) with brain tumors: results from the international MOBI-Kids study

Author: IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Zumel-Marne, Angela, Kundi, Michael, Castaño-Vinyals, Gemma, Alguacil, Juan, Petridou, Eleni Th, Georgakis, Marios K, Morales-Suárez-Varela, Maria, Sadetzki, Siegal, Piro, Sara, Nagrani, Rajini, Filippini, Graziella, Hutter, Hans-Peter, Dikshit, Rajesh, Woehrer, Adelheid, Maule, Milena, Weinmann, Tobias, Krewski, Daniel, T Mannetje, Andrea, Momoli, Franco, Lacour, Brigitte, Mattioli, Stefano, Spinelli, John J, Ritvo, Paul, Remen, Thomas, Kojimahara, Noriko, Eng, Amanda, Thurston, Angela, Lim, Hyungryul, Ha, Mina, Yamaguchi, Naohito, Mohipp, Charmaine, Bouka, Evdoxia, Eastman, Chelsea, Vermeulen, Roel, Kromhout, Hans, Cardis, Elisabeth, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Zumel-Marne, Angela, Kundi, Michael, Castaño-Vinyals, Gemma, Alguacil, Juan, Petridou, Eleni Th, Georgakis, Marios K, Morales-Suárez-Varela, Maria, Sadetzki, Siegal, Piro, Sara, Nagrani, Rajini, Filippini, Graziella, Hutter, Hans-Peter, Dikshit, Rajesh, Woehrer, Adelheid, Maule, Milena, Weinmann, Tobias, Krewski, Daniel, T Mannetje, Andrea, Momoli, Franco, Lacour, Brigitte, Mattioli, Stefano, Spinelli, John J, Ritvo, Paul, Remen, Thomas, Kojimahara, Noriko, Eng, Amanda, Thurston, Angela, Lim, Hyungryul, Ha, Mina, Yamaguchi, Naohito, Mohipp, Charmaine, Bouka, Evdoxia, Eastman, Chelsea, Vermeulen, Roel, Kromhout, Hans, and Cardis, Elisabeth
Published: 2020

22. Clinical presentation of young people (10-24 years old) with brain tumors: results from the international MOBI-Kids study

Author: IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Zumel-Marne, Angela, Kundi, Michael, Castaño-Vinyals, Gemma, Alguacil, Juan, Petridou, Eleni Th, Georgakis, Marios K, Morales-Suárez-Varela, Maria, Sadetzki, Siegal, Piro, Sara, Nagrani, Rajini, Filippini, Graziella, Hutter, Hans-Peter, Dikshit, Rajesh, Woehrer, Adelheid, Maule, Milena, Weinmann, Tobias, Krewski, Daniel, T Mannetje, Andrea, Momoli, Franco, Lacour, Brigitte, Mattioli, Stefano, Spinelli, John J, Ritvo, Paul, Remen, Thomas, Kojimahara, Noriko, Eng, Amanda, Thurston, Angela, Lim, Hyungryul, Ha, Mina, Yamaguchi, Naohito, Mohipp, Charmaine, Bouka, Evdoxia, Eastman, Chelsea, Vermeulen, Roel, Kromhout, Hans, Cardis, Elisabeth, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Zumel-Marne, Angela, Kundi, Michael, Castaño-Vinyals, Gemma, Alguacil, Juan, Petridou, Eleni Th, Georgakis, Marios K, Morales-Suárez-Varela, Maria, Sadetzki, Siegal, Piro, Sara, Nagrani, Rajini, Filippini, Graziella, Hutter, Hans-Peter, Dikshit, Rajesh, Woehrer, Adelheid, Maule, Milena, Weinmann, Tobias, Krewski, Daniel, T Mannetje, Andrea, Momoli, Franco, Lacour, Brigitte, Mattioli, Stefano, Spinelli, John J, Ritvo, Paul, Remen, Thomas, Kojimahara, Noriko, Eng, Amanda, Thurston, Angela, Lim, Hyungryul, Ha, Mina, Yamaguchi, Naohito, Mohipp, Charmaine, Bouka, Evdoxia, Eastman, Chelsea, Vermeulen, Roel, Kromhout, Hans, and Cardis, Elisabeth
Published: 2020

23. Clinical presentation of young people (10-24 years old) with brain tumors: results from the international MOBI-Kids study

Author: IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Zumel-Marne, Angela, Kundi, Michael, Castaño-Vinyals, Gemma, Alguacil, Juan, Petridou, Eleni Th, Georgakis, Marios K, Morales-Suárez-Varela, Maria, Sadetzki, Siegal, Piro, Sara, Nagrani, Rajini, Filippini, Graziella, Hutter, Hans-Peter, Dikshit, Rajesh, Woehrer, Adelheid, Maule, Milena, Weinmann, Tobias, Krewski, Daniel, T Mannetje, Andrea, Momoli, Franco, Lacour, Brigitte, Mattioli, Stefano, Spinelli, John J, Ritvo, Paul, Remen, Thomas, Kojimahara, Noriko, Eng, Amanda, Thurston, Angela, Lim, Hyungryul, Ha, Mina, Yamaguchi, Naohito, Mohipp, Charmaine, Bouka, Evdoxia, Eastman, Chelsea, Vermeulen, Roel, Kromhout, Hans, Cardis, Elisabeth, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Zumel-Marne, Angela, Kundi, Michael, Castaño-Vinyals, Gemma, Alguacil, Juan, Petridou, Eleni Th, Georgakis, Marios K, Morales-Suárez-Varela, Maria, Sadetzki, Siegal, Piro, Sara, Nagrani, Rajini, Filippini, Graziella, Hutter, Hans-Peter, Dikshit, Rajesh, Woehrer, Adelheid, Maule, Milena, Weinmann, Tobias, Krewski, Daniel, T Mannetje, Andrea, Momoli, Franco, Lacour, Brigitte, Mattioli, Stefano, Spinelli, John J, Ritvo, Paul, Remen, Thomas, Kojimahara, Noriko, Eng, Amanda, Thurston, Angela, Lim, Hyungryul, Ha, Mina, Yamaguchi, Naohito, Mohipp, Charmaine, Bouka, Evdoxia, Eastman, Chelsea, Vermeulen, Roel, Kromhout, Hans, and Cardis, Elisabeth
Published: 2020

24. Exploring the boundaries of endovascular aneurysm repair: studying an all-comers population

Author: 't Mannetje, Yannick Willem and 't Mannetje, Yannick Willem
Abstract: An abdominal aortic aneurysm can be treated endovascularly since the early 1990s. In the endovascular technique, a stent is placed through the groin, which is less invasive than the open technique. An important limitation is that ruptured and complex aneurysms are less suitable and more long-term complications are seen. With the help of registration studies, this thesis investigated how stents function at the extremes of the manufacturers' instructions for use. The thesis shows that in the case of ruptured aneurysms, the technical results are good. Additionally, it is shown that in complex aneurysms the short-term number of complications is not unacceptable, despite the challenging anatomy. The long-term results will have to be determined in the future. The above results can contribute to determining the optimal treatment strategy of ruptured and complex aneurysms.
Published: 2020

25. Sex ratio of the offspring of New Zealand phenoxy herbicide producers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Author: 't Mannetje, Andrea, 't Mannetje, Andrea, Eng, Amanda, Walls, Chris, Dryson, Evan, Kogevinas, Manolis, Brooks, Collin, McLean, Dave, Cheng, Soo, Smith, Allan H, Pearce, Neil, 't Mannetje, Andrea, 't Mannetje, Andrea, Eng, Amanda, Walls, Chris, Dryson, Evan, Kogevinas, Manolis, Brooks, Collin, McLean, Dave, Cheng, Soo, Smith, Allan H, and Pearce, Neil
Abstract: ObjectivesExposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) has inconsistently been associated with a decreased sex ratio of the offspring (number of male births divided by total births). We conducted a study among men and women who were employed in a New Zealand phenoxy herbicide production plant between 1969 and 1984, to study their offspring sex ratio in relation to their back-calculated TCDD serum concentrations determined in 2007/2008.MethodsA total of 127 men and 21 women reported that 355 children were conceived after starting employment at the plant. The association between their lipid-standardised TCDD serum concentrations back-calculated to the time of their offspring's birth and the probability of a male birth was estimated through logistic regression, adjusting for the age of the exposed parent at birth, current body mass index and smoking.ResultsThe overall sex ratio was 0.55 (197 boys, 158 girls). For fathers with serum TCDD concentrations ≥20 pg/g lipid at time of birth, the sex ratio was 0.47 (OR 0.49; 95% CI 0.30 to 0.79). The probability of a male birth decreased with higher paternal serum TCDD at time of birth (<4; 4-20; 20-100; ≥100 pg/g lipid), with ORs of 1.00 (reference); 1.00 (95% CI 0.50 to 2.02); 0.52 (95% CI 0.29 to 0.92); 0.45 (95% CI 0.23 to 0.89), p trend 0.007. For exposed mothers, the sex ratio was not reduced.ConclusionsThis study indicates that paternal serum TCDD concentrations in excess of an estimated 20 pg/g lipid at time of conception are associated with a reduced sex ratio.
Published: 2017

26. Comparison of midterm results for the Talent and Endurant stent graft

Author: 't Mannetje, Yannick W., 't Mannetje, Yannick W., Cuypers, Philippe W. M., Saleem, Ben R., Bode, Aron S., Teijink, Joep A. W., van Sambeek, Marc R. H. M., 't Mannetje, Yannick W., 't Mannetje, Yannick W., Cuypers, Philippe W. M., Saleem, Ben R., Bode, Aron S., Teijink, Joep A. W., and van Sambeek, Marc R. H. M.
Abstract: Objective: Stent graft evolution is often addressed as a cause for improved outcomes of endovascular aneurysm repair for patients with an abdominal aortic aneurysm. In this study, we directly compared the midterm result of Endurant stent graft with its predecessor, the Talent stent graft (both Medtronic, Santa Rosa, Calif).Methods: Patient treated from January 2005 to December 2010 in a single tertiary center in The Netherlands with a Talent or Endurant stent graft were eligible for inclusion. Ruptured abdominal aortic aneurysms or patients with previous aortic surgery were excluded. The primary end point was the Kaplan-Meier estimated freedom from secondary interventions. Secondary end points were perioperative outcomes and indications for secondary interventions.Results: In total, 221 patients were included (131 Endurant and 90 Talent). At baseline, the median aortic bifurcation was narrower for the Endurant (30 mm vs 39 mm; PConclusions: Evolution from the Talent stent graft into the Endurant has resulted in significant reduction of infrarenal neck-related complications; on the other hand, iliac interventions increased. The overall midterm secondary intervention rate was comparable. (J Vasc Surg 2017;66:735-42.)
Published: 2017

27. Sex ratio of the offspring of New Zealand phenoxy herbicide producers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Author: 't Mannetje, Andrea, 't Mannetje, Andrea, Eng, Amanda, Walls, Chris, Dryson, Evan, Kogevinas, Manolis, Brooks, Collin, McLean, Dave, Cheng, Soo, Smith, Allan H, Pearce, Neil, 't Mannetje, Andrea, 't Mannetje, Andrea, Eng, Amanda, Walls, Chris, Dryson, Evan, Kogevinas, Manolis, Brooks, Collin, McLean, Dave, Cheng, Soo, Smith, Allan H, and Pearce, Neil
Abstract: ObjectivesExposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) has inconsistently been associated with a decreased sex ratio of the offspring (number of male births divided by total births). We conducted a study among men and women who were employed in a New Zealand phenoxy herbicide production plant between 1969 and 1984, to study their offspring sex ratio in relation to their back-calculated TCDD serum concentrations determined in 2007/2008.MethodsA total of 127 men and 21 women reported that 355 children were conceived after starting employment at the plant. The association between their lipid-standardised TCDD serum concentrations back-calculated to the time of their offspring's birth and the probability of a male birth was estimated through logistic regression, adjusting for the age of the exposed parent at birth, current body mass index and smoking.ResultsThe overall sex ratio was 0.55 (197 boys, 158 girls). For fathers with serum TCDD concentrations ≥20 pg/g lipid at time of birth, the sex ratio was 0.47 (OR 0.49; 95% CI 0.30 to 0.79). The probability of a male birth decreased with higher paternal serum TCDD at time of birth (<4; 4-20; 20-100; ≥100 pg/g lipid), with ORs of 1.00 (reference); 1.00 (95% CI 0.50 to 2.02); 0.52 (95% CI 0.29 to 0.92); 0.45 (95% CI 0.23 to 0.89), p trend 0.007. For exposed mothers, the sex ratio was not reduced.ConclusionsThis study indicates that paternal serum TCDD concentrations in excess of an estimated 20 pg/g lipid at time of conception are associated with a reduced sex ratio.
Published: 2017

28. Occupation and motor neuron disease : a New Zealand case-control study

Author: Chen, Grace Xia, 't Mannetje, Andrea Martine, Douwes, Jeroen, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, D'Souza, Wendyl, McConnell, Melanie, Glass, Bill, Brewer, Naomi, McLean, David J, Chen, Grace Xia, 't Mannetje, Andrea Martine, Douwes, Jeroen, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, D'Souza, Wendyl, McConnell, Melanie, Glass, Bill, Brewer, Naomi, and McLean, David J
Published: 2019

29. Occupation and motor neuron disease : a New Zealand case-control study

Author: Chen, Grace Xia, 't Mannetje, Andrea Martine, Douwes, Jeroen, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, D'Souza, Wendyl, McConnell, Melanie, Glass, Bill, Brewer, Naomi, McLean, David J, Chen, Grace Xia, 't Mannetje, Andrea Martine, Douwes, Jeroen, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, D'Souza, Wendyl, McConnell, Melanie, Glass, Bill, Brewer, Naomi, and McLean, David J
Published: 2019

30. Self-report occupational exposures and mnd in New Zealand

Author: One Health Chemisch, dIRAS RA-2, Chen, Grace, Mannetje, Andrea't, Douwes, Jeroen, Van Den Berg, Leonard, McLean, Dave, Pearce, Neil, Kromhout, Hans, D'Souza, Wendyl, McConnell, Melanie, One Health Chemisch, dIRAS RA-2, Chen, Grace, Mannetje, Andrea't, Douwes, Jeroen, Van Den Berg, Leonard, McLean, Dave, Pearce, Neil, Kromhout, Hans, D'Souza, Wendyl, and McConnell, Melanie
Published: 2019

31. Occupation and motor neuron disease : a New Zealand case-control study

Author: Chen, Grace Xia, 't Mannetje, Andrea Martine, Douwes, Jeroen, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, D'Souza, Wendyl, McConnell, Melanie, Glass, Bill, Brewer, Naomi, McLean, David J, Chen, Grace Xia, 't Mannetje, Andrea Martine, Douwes, Jeroen, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, D'Souza, Wendyl, McConnell, Melanie, Glass, Bill, Brewer, Naomi, and McLean, David J
Published: 2019

32. Self-report occupational exposures and mnd in New Zealand

Author: One Health Chemisch, dIRAS RA-2, Chen, Grace, Mannetje, Andrea't, Douwes, Jeroen, Van Den Berg, Leonard, McLean, Dave, Pearce, Neil, Kromhout, Hans, D'Souza, Wendyl, McConnell, Melanie, One Health Chemisch, dIRAS RA-2, Chen, Grace, Mannetje, Andrea't, Douwes, Jeroen, Van Den Berg, Leonard, McLean, Dave, Pearce, Neil, Kromhout, Hans, D'Souza, Wendyl, and McConnell, Melanie
Published: 2019

33. Occupation and motor neuron disease: a New Zealand case-control study

Author: ZL Neuromusculaire Ziekten Medisch, Brain, Regenerative Medicine and Stem Cells, Projectafdeling ALS, Chen, Grace Xia, 't Mannetje, Andrea Martine, Douwes, Jeroen, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, D'Souza, Wendyl, McConnell, Melanie, Glass, Bill, Brewer, Naomi, McLean, David J, ZL Neuromusculaire Ziekten Medisch, Brain, Regenerative Medicine and Stem Cells, Projectafdeling ALS, Chen, Grace Xia, 't Mannetje, Andrea Martine, Douwes, Jeroen, van den Berg, Leonard, Pearce, Neil, Kromhout, Hans, D'Souza, Wendyl, McConnell, Melanie, Glass, Bill, Brewer, Naomi, and McLean, David J
Published: 2019

34. Self-report occupational exposures and mnd in New Zealand

Author: One Health Chemisch, dIRAS RA-2, Chen, Grace, Mannetje, Andrea't, Douwes, Jeroen, Van Den Berg, Leonard, McLean, Dave, Pearce, Neil, Kromhout, Hans, D'Souza, Wendyl, McConnell, Melanie, One Health Chemisch, dIRAS RA-2, Chen, Grace, Mannetje, Andrea't, Douwes, Jeroen, Van Den Berg, Leonard, McLean, Dave, Pearce, Neil, Kromhout, Hans, D'Souza, Wendyl, and McConnell, Melanie
Published: 2019

35. Serum concentrations of chlorinated dibenzo-p-dioxins, furans and PCBs, among former phenoxy herbicide production workers and firefighters in New Zealand.

Author: 't Mannetje, Andrea, 't Mannetje, Andrea, Eng, Amanda, Walls, Chris, Dryson, Evan, McLean, Dave, Kogevinas, Manolis, Fowles, Jeff, Borman, Barry, O'Connor, Patrick, Cheng, Soo, Brooks, Collin, H Smith, Allan, Pearce, Neil, 't Mannetje, Andrea, 't Mannetje, Andrea, Eng, Amanda, Walls, Chris, Dryson, Evan, McLean, Dave, Kogevinas, Manolis, Fowles, Jeff, Borman, Barry, O'Connor, Patrick, Cheng, Soo, Brooks, Collin, H Smith, Allan, and Pearce, Neil
Abstract: PurposeTo quantify serum concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and dioxin-like compounds in former phenoxy herbicide production plant workers and firefighters, 20 years after 2,4,5-T production ceased.MethodsOf 1025 workers employed any time during 1969-1984, 430 were randomly selected and invited to take part in a morbidity survey and provide a blood sample; 244 (57%) participated. Firefighters stationed in close proximity of the plant and/or engaged in call-outs to the plant between 1962 and 1987 also participated (39 of 70 invited). Reported here are the serum concentrations of TCDD and other chlorinated dibenzo-dioxins, dibenzofurans, and polychlorinated biphenyls (PCBs). Determinants of the serum concentrations were assessed using linear regression.ResultsThe 60 men who had worked in the phenoxy/TCP production area had a mean TCDD serum concentration of 19.1 pg/g lipid, three times the mean concentration of the 141 men and 43 women employed in other parts of the plant (6.3 and 6.0 pg/g respectively), and more than 10 times the mean for the firefighters (1.6 pg/g). Duration of employment in phenoxy herbicide synthesis, maintenance work, and work as a boilerman, chemist, and packer were associated with increased serum concentrations of TCDD and 1,2,3,4,7-pentachlorodibenzo-p-dioxin (PeCDD). Employment as a boilerman was also associated with elevated serum concentrations of PCBs.ConclusionsOccupations in the plant associated with phenoxy herbicide synthesis had elevated levels of TCDD and PeCDD. Most other people working within the plant, and the local firefighters, had serum concentrations of dioxin-like compounds comparable to those of the general population.
Published: 2016

36. Serum concentrations of chlorinated dibenzo-p-dioxins, furans and PCBs, among former phenoxy herbicide production workers and firefighters in New Zealand.

Author: 't Mannetje, Andrea, 't Mannetje, Andrea, Eng, Amanda, Walls, Chris, Dryson, Evan, McLean, Dave, Kogevinas, Manolis, Fowles, Jeff, Borman, Barry, O'Connor, Patrick, Cheng, Soo, Brooks, Collin, H Smith, Allan, Pearce, Neil, 't Mannetje, Andrea, 't Mannetje, Andrea, Eng, Amanda, Walls, Chris, Dryson, Evan, McLean, Dave, Kogevinas, Manolis, Fowles, Jeff, Borman, Barry, O'Connor, Patrick, Cheng, Soo, Brooks, Collin, H Smith, Allan, and Pearce, Neil
Abstract: PurposeTo quantify serum concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and dioxin-like compounds in former phenoxy herbicide production plant workers and firefighters, 20 years after 2,4,5-T production ceased.MethodsOf 1025 workers employed any time during 1969-1984, 430 were randomly selected and invited to take part in a morbidity survey and provide a blood sample; 244 (57%) participated. Firefighters stationed in close proximity of the plant and/or engaged in call-outs to the plant between 1962 and 1987 also participated (39 of 70 invited). Reported here are the serum concentrations of TCDD and other chlorinated dibenzo-dioxins, dibenzofurans, and polychlorinated biphenyls (PCBs). Determinants of the serum concentrations were assessed using linear regression.ResultsThe 60 men who had worked in the phenoxy/TCP production area had a mean TCDD serum concentration of 19.1 pg/g lipid, three times the mean concentration of the 141 men and 43 women employed in other parts of the plant (6.3 and 6.0 pg/g respectively), and more than 10 times the mean for the firefighters (1.6 pg/g). Duration of employment in phenoxy herbicide synthesis, maintenance work, and work as a boilerman, chemist, and packer were associated with increased serum concentrations of TCDD and 1,2,3,4,7-pentachlorodibenzo-p-dioxin (PeCDD). Employment as a boilerman was also associated with elevated serum concentrations of PCBs.ConclusionsOccupations in the plant associated with phenoxy herbicide synthesis had elevated levels of TCDD and PeCDD. Most other people working within the plant, and the local firefighters, had serum concentrations of dioxin-like compounds comparable to those of the general population.
Published: 2016

37. Recall of mobile phone usage and laterality in young people: The multinational Mobi-Expo study

Author: Goedhart, Geertje, van Wel, Luuk, Langer, Chelsea Eastman, de Llobet Viladoms, Patricia, Wiart, Joe, Hours, Martine, Kromhout, Hans, Benke, Geza, Bouka, Evdoxia, Bruchim, Revital, Choi, Kyung-Hwa, Eng, Amanda, Ha, Mina, Huss, Anke, Kiyohara, Kosuke, Kojimahara, Noriko, Krewski, Daniel, Lacour, Brigitte, 't Mannetje, Andrea, Maule, Milena, Migliore, Enrica, Mohipp, Charmaine, Momoli, Franco, Petridou, Eleni Th, Radon, Katja, Remen, Thomas, Sadetzki, Siegal, Sim, Malcolm R, Weinmann, Tobias, Cardis, Elisabeth, Vrijheid, Martine, Vermeulen, Roel, Goedhart, Geertje, van Wel, Luuk, Langer, Chelsea Eastman, de Llobet Viladoms, Patricia, Wiart, Joe, Hours, Martine, Kromhout, Hans, Benke, Geza, Bouka, Evdoxia, Bruchim, Revital, Choi, Kyung-Hwa, Eng, Amanda, Ha, Mina, Huss, Anke, Kiyohara, Kosuke, Kojimahara, Noriko, Krewski, Daniel, Lacour, Brigitte, 't Mannetje, Andrea, Maule, Milena, Migliore, Enrica, Mohipp, Charmaine, Momoli, Franco, Petridou, Eleni Th, Radon, Katja, Remen, Thomas, Sadetzki, Siegal, Sim, Malcolm R, Weinmann, Tobias, Cardis, Elisabeth, Vrijheid, Martine, and Vermeulen, Roel
Abstract: OBJECTIVE: To study recall of mobile phone usage, including laterality and hands-free use, in young people.METHODS: Actual mobile phone use was recorded among volunteers aged between 10 and 24 years from 12 countries by the software application XMobiSense and was compared with self-reported mobile phone use at 6 and 18 months after using the application. The application recorded number and duration of voice calls, number of text messages, amount of data transfer, laterality (% of call time the phone was near the right or left side of the head, or neither), and hands-free usage. After data cleaning, 466 participants were available for the main analyses (recorded vs. self-reported phone use after 6 months).RESULTS: Participants were on average 18.6 years old (IQR 15.2-21.8 years). The Spearman correlation coefficients between recorded and self-reported (after 6 months) number and duration of voice calls were 0.68 and 0.65, respectively. Number of calls was on average underestimated by the participants (adjusted geometric mean ratio (GMR) self-report/recorded = 0.52, 95% CI = 0.47-0.58), while duration of calls was overestimated (GMR=1.32, 95%, CI = 1.15-1.52). The ratios significantly differed by country, age, maternal educational level, and level of reported phone use, but not by time of the interview (6 vs. 18 months). Individuals who reported low mobile phone use underestimated their use, while individuals who reported the highest level of phone use were more likely to overestimate their use. Individuals who reported using the phone mainly on the right side of the head used it more on the right (71.1%) than the left (28.9%) side. Self-reported left side users, however, used the phone only slightly more on the left (53.3%) than the right (46.7%) side. Recorded percentage hands-free use (headset, speaker mode, Bluetooth) increased with increasing self-reported frequency of hands-free device usage. Frequent (≥50% of call time) reported headset or spea
Published: 2018

38. Recall of mobile phone usage and laterality in young people: The multinational Mobi-Expo study

Author: One Health Chemisch, dIRAS RA-2, Goedhart, Geertje, van Wel, Luuk, Langer, Chelsea Eastman, de Llobet Viladoms, Patricia, Wiart, Joe, Hours, Martine, Kromhout, Hans, Benke, Geza, Bouka, Evdoxia, Bruchim, Revital, Choi, Kyung-Hwa, Eng, Amanda, Ha, Mina, Huss, Anke, Kiyohara, Kosuke, Kojimahara, Noriko, Krewski, Daniel, Lacour, Brigitte, 't Mannetje, Andrea, Maule, Milena, Migliore, Enrica, Mohipp, Charmaine, Momoli, Franco, Petridou, Eleni Th, Radon, Katja, Remen, Thomas, Sadetzki, Siegal, Sim, Malcolm R, Weinmann, Tobias, Cardis, Elisabeth, Vrijheid, Martine, Vermeulen, Roel, One Health Chemisch, dIRAS RA-2, Goedhart, Geertje, van Wel, Luuk, Langer, Chelsea Eastman, de Llobet Viladoms, Patricia, Wiart, Joe, Hours, Martine, Kromhout, Hans, Benke, Geza, Bouka, Evdoxia, Bruchim, Revital, Choi, Kyung-Hwa, Eng, Amanda, Ha, Mina, Huss, Anke, Kiyohara, Kosuke, Kojimahara, Noriko, Krewski, Daniel, Lacour, Brigitte, 't Mannetje, Andrea, Maule, Milena, Migliore, Enrica, Mohipp, Charmaine, Momoli, Franco, Petridou, Eleni Th, Radon, Katja, Remen, Thomas, Sadetzki, Siegal, Sim, Malcolm R, Weinmann, Tobias, Cardis, Elisabeth, Vrijheid, Martine, and Vermeulen, Roel
Published: 2018

39. Recall of mobile phone usage and laterality in young people: The multinational Mobi-Expo study

Author: One Health Chemisch, dIRAS RA-2, Goedhart, Geertje, van Wel, Luuk, Langer, Chelsea Eastman, de Llobet Viladoms, Patricia, Wiart, Joe, Hours, Martine, Kromhout, Hans, Benke, Geza, Bouka, Evdoxia, Bruchim, Revital, Choi, Kyung-Hwa, Eng, Amanda, Ha, Mina, Huss, Anke, Kiyohara, Kosuke, Kojimahara, Noriko, Krewski, Daniel, Lacour, Brigitte, 't Mannetje, Andrea, Maule, Milena, Migliore, Enrica, Mohipp, Charmaine, Momoli, Franco, Petridou, Eleni Th, Radon, Katja, Remen, Thomas, Sadetzki, Siegal, Sim, Malcolm R, Weinmann, Tobias, Cardis, Elisabeth, Vrijheid, Martine, Vermeulen, Roel, One Health Chemisch, dIRAS RA-2, Goedhart, Geertje, van Wel, Luuk, Langer, Chelsea Eastman, de Llobet Viladoms, Patricia, Wiart, Joe, Hours, Martine, Kromhout, Hans, Benke, Geza, Bouka, Evdoxia, Bruchim, Revital, Choi, Kyung-Hwa, Eng, Amanda, Ha, Mina, Huss, Anke, Kiyohara, Kosuke, Kojimahara, Noriko, Krewski, Daniel, Lacour, Brigitte, 't Mannetje, Andrea, Maule, Milena, Migliore, Enrica, Mohipp, Charmaine, Momoli, Franco, Petridou, Eleni Th, Radon, Katja, Remen, Thomas, Sadetzki, Siegal, Sim, Malcolm R, Weinmann, Tobias, Cardis, Elisabeth, Vrijheid, Martine, and Vermeulen, Roel
Published: 2018

40. Recall of mobile phone usage and laterality in young people: The multinational Mobi-Expo study

Author: One Health Chemisch, dIRAS RA-2, Goedhart, Geertje, van Wel, Luuk, Langer, Chelsea Eastman, de Llobet Viladoms, Patricia, Wiart, Joe, Hours, Martine, Kromhout, Hans, Benke, Geza, Bouka, Evdoxia, Bruchim, Revital, Choi, Kyung-Hwa, Eng, Amanda, Ha, Mina, Huss, Anke, Kiyohara, Kosuke, Kojimahara, Noriko, Krewski, Daniel, Lacour, Brigitte, 't Mannetje, Andrea, Maule, Milena, Migliore, Enrica, Mohipp, Charmaine, Momoli, Franco, Petridou, Eleni Th, Radon, Katja, Remen, Thomas, Sadetzki, Siegal, Sim, Malcolm R, Weinmann, Tobias, Cardis, Elisabeth, Vrijheid, Martine, Vermeulen, Roel, One Health Chemisch, dIRAS RA-2, Goedhart, Geertje, van Wel, Luuk, Langer, Chelsea Eastman, de Llobet Viladoms, Patricia, Wiart, Joe, Hours, Martine, Kromhout, Hans, Benke, Geza, Bouka, Evdoxia, Bruchim, Revital, Choi, Kyung-Hwa, Eng, Amanda, Ha, Mina, Huss, Anke, Kiyohara, Kosuke, Kojimahara, Noriko, Krewski, Daniel, Lacour, Brigitte, 't Mannetje, Andrea, Maule, Milena, Migliore, Enrica, Mohipp, Charmaine, Momoli, Franco, Petridou, Eleni Th, Radon, Katja, Remen, Thomas, Sadetzki, Siegal, Sim, Malcolm R, Weinmann, Tobias, Cardis, Elisabeth, Vrijheid, Martine, and Vermeulen, Roel
Published: 2018

41. Estimated infant intake of persistent organic pollutants through breast milk in New Zealand.

Author: 't Mannetje, Andrea, 't Mannetje, Andrea, Coakley, Jonathan, Bridgen, Phil, Smith, Allan H, Read, Deborah, Pearce, Neil, Douwes, Jeroen, 't Mannetje, Andrea, 't Mannetje, Andrea, Coakley, Jonathan, Bridgen, Phil, Smith, Allan H, Read, Deborah, Pearce, Neil, and Douwes, Jeroen
Abstract: AimTo estimate average infant daily intake of chlorinated persistent organic pollutants (POPs) through the consumption of breast milk in New Zealand.MethodBreast milk of 39 first-time mothers aged 20-30 years was collected during 2007-2010 and analysed for persistent organic pollutants including dioxin-like compounds and organochlorine pesticides. The quantity of POPs consumed by infants assuming exclusive breast feeding was estimated by calculating the Estimated Daily Intake (EDI) expressed as amount consumed through breast milk per kilogram of body weight per day.ResultsOf all POPs quantified, the EDI of DDT (principally in the form of its metabolite p,p'-DDE) was the highest (1.6 mcg/kg/day), and above the tolerable daily intake (TDI) of 0.5 mcg/kg/day. The mean EDI for dioxin-like compounds (including PCDD/Fs and PCBs) was 19.7 pg TEQ(toxic equivalency)/kg/day, which is among the lowest reported worldwide, yet above the TDI of 1 pg TEQ/kg/day. The EDI of HCH, HCB, dieldrin, heptachlor and mirex were 32.9, 37.9, 39.4, 2.0, and 0.9 ng/kg/day respectively, all of which were below the current TDI. Age of the mother was positively associated with higher EDIs for the infant, particularly for total-TEQ and total-DDT.ConcluisonInfant daily intakes of chlorinated POPs through breast milk estimated for New Zealand are low or average by international comparison, and 5 times lower than 25 years ago. Future breast milk monitoring will determine whether this diminishing trend is continuing as well as providing monitoring information on other POPs.
Published: 2014

42. Estimated infant intake of persistent organic pollutants through breast milk in New Zealand.

Author: 't Mannetje, Andrea, 't Mannetje, Andrea, Coakley, Jonathan, Bridgen, Phil, Smith, Allan H, Read, Deborah, Pearce, Neil, Douwes, Jeroen, 't Mannetje, Andrea, 't Mannetje, Andrea, Coakley, Jonathan, Bridgen, Phil, Smith, Allan H, Read, Deborah, Pearce, Neil, and Douwes, Jeroen
Abstract: AimTo estimate average infant daily intake of chlorinated persistent organic pollutants (POPs) through the consumption of breast milk in New Zealand.MethodBreast milk of 39 first-time mothers aged 20-30 years was collected during 2007-2010 and analysed for persistent organic pollutants including dioxin-like compounds and organochlorine pesticides. The quantity of POPs consumed by infants assuming exclusive breast feeding was estimated by calculating the Estimated Daily Intake (EDI) expressed as amount consumed through breast milk per kilogram of body weight per day.ResultsOf all POPs quantified, the EDI of DDT (principally in the form of its metabolite p,p'-DDE) was the highest (1.6 mcg/kg/day), and above the tolerable daily intake (TDI) of 0.5 mcg/kg/day. The mean EDI for dioxin-like compounds (including PCDD/Fs and PCBs) was 19.7 pg TEQ(toxic equivalency)/kg/day, which is among the lowest reported worldwide, yet above the TDI of 1 pg TEQ/kg/day. The EDI of HCH, HCB, dieldrin, heptachlor and mirex were 32.9, 37.9, 39.4, 2.0, and 0.9 ng/kg/day respectively, all of which were below the current TDI. Age of the mother was positively associated with higher EDIs for the infant, particularly for total-TEQ and total-DDT.ConcluisonInfant daily intakes of chlorinated POPs through breast milk estimated for New Zealand are low or average by international comparison, and 5 times lower than 25 years ago. Future breast milk monitoring will determine whether this diminishing trend is continuing as well as providing monitoring information on other POPs.
Published: 2014

43. Patterns of cellular phone use among young people in 12 countries: Implications for RF exposure

Author: Langer, Chelsea Eastman, de Llobet Viladoms, Patricia, Dalmau-Bueno, Albert, Wiart, Joe, Goedhart, Geertje, Hours, Martine, Benke, Geza P, Bouka, Evdoxia, Bruchim, Revital, Choi, Kyung-Hwa, Eng, Amanda, Ha, Mina, Karalexi, Maria, Kiyohara, Kosuke, Kojimahara, Noriko, Krewski, Daniel, Kromhout, Hans, Lacour, Brigitte, 't Mannetje, Andrea, Maule, Milena, Migliore, Enrica, Mohipp, Charmaine, Momoli, Franco, Petridou, Eleni, Radon, Katja, Remen, Thomas, Sadetzki, Siegal, Sim, Malcolm R, Weinmann, Tobias, Vermeulen, Roel, Cardis, Elisabeth, Vrijheid, Martine, Langer, Chelsea Eastman, de Llobet Viladoms, Patricia, Dalmau-Bueno, Albert, Wiart, Joe, Goedhart, Geertje, Hours, Martine, Benke, Geza P, Bouka, Evdoxia, Bruchim, Revital, Choi, Kyung-Hwa, Eng, Amanda, Ha, Mina, Karalexi, Maria, Kiyohara, Kosuke, Kojimahara, Noriko, Krewski, Daniel, Kromhout, Hans, Lacour, Brigitte, 't Mannetje, Andrea, Maule, Milena, Migliore, Enrica, Mohipp, Charmaine, Momoli, Franco, Petridou, Eleni, Radon, Katja, Remen, Thomas, Sadetzki, Siegal, Sim, Malcolm R, Weinmann, Tobias, Vermeulen, Roel, Cardis, Elisabeth, and Vrijheid, Martine
Abstract: Characterizing exposure to radiofrequency (RF) fields from wireless telecommunications technologies during childhood and adolescence is a research priority in investigating the health effects of RF. The Mobi-Expo study aimed to describe characteristics and determinants of cellular phone use in 534 young people (10-24years) in 12 countries. The study used a specifically designed software application installed on smartphones to collect data on the use of wireless telecommunications devices within this age group. The role of gender, age, maternal education, calendar period, and country was evaluated through multivariate models mutually adjusting for all variables. Call number and duration were higher among females compared to males (geometric mean (GM) ratio 1.17 and 1.42, respectively), among 20-24year olds compared to 10-14year olds (GM ratio 2.09 and 4.40, respectively), and among lowest compared to highest social classes (GM ratio 1.52 and 1.58, respectively). The number of SMS was higher in females (GM ratio 1.46) and the middle age group (15-19year olds: GM ratio 2.21 compared to 10-14year olds) and decreased over time. Data use was highest in the oldest age group, whereas Wi-Fi use was highest in the middle age group. Both data and Wi-Fi use increased over time. Large differences in the number and duration of calls, SMS, and data/Wi-Fi use were seen by country, with country and age accounting for up to 50% of the variance. Hands-free and laterality of use did not show significant differences by sex, age, education, study period, or country. Although limited by a convenience sample, these results provide valuable insights to the design, analysis, and interpretation of future epidemiological studies concerning the health effects of exposure resulting from cellular phone use in young people. In addition, the information provided by this research may be used to design strategies to minimize RF exposure.
Published: 2017

44. Wood Dust in Joineries and Furniture Manufacturing: An Exposure Determinant and Intervention Study

Author: Douwes, Jeroen, Cheung, Kerry, Prezant, Bradley, Sharp, Mark, Corbin, Marine, McLean, Dave, 't Mannetje, Andrea, Schlunssen, Vivi, Sigsgaard, Torben, Kromhout, Hans, LaMontagne, Anthony D, Pearce, Neil, McGlothlin, James D, Douwes, Jeroen, Cheung, Kerry, Prezant, Bradley, Sharp, Mark, Corbin, Marine, McLean, Dave, 't Mannetje, Andrea, Schlunssen, Vivi, Sigsgaard, Torben, Kromhout, Hans, LaMontagne, Anthony D, Pearce, Neil, and McGlothlin, James D
Abstract: Objectives: To assess wood dust exposures and determinants in joineries and furniture manufacturing and to evaluate the efficacy of specific interventions on dust emissions under laboratory conditions. Also, in a subsequent follow-up study in a small sample of joinery workshops, we aimed to develop, implement, and evaluate a cost-effective and practicable intervention to reduce dust exposures.Methods: Personal inhalable dust (n = 201) was measured in 99 workers from 10 joineries and 3 furniture-making factories. To assess exposure determinants, full-shift video exposure monitoring (VEM) was conducted in 19 workers and task-based VEM in 32 workers (in 7 joineries and 3 furniture factories). We assessed the efficacy of vacuum extraction on hand tools and the use of vacuum cleaners instead of sweeping and dry wiping under laboratory conditions. These measures were subsequently implemented in three joinery workshops with 'high' (>4 mg m-3) and one with 'low' (<2 mg m-3) baseline exposures. We also included two control workshops (one 'low' and one 'high' exposure workshop) in which no interventions were implemented. Exposures were measured 4 months prior and 4 months following the intervention.Results: Average (geometric means) exposures in joinery and furniture making were 2.5 mg m-3 [geometric standard deviations (GSD) 2.5] and 0.6 mg m-3 (GSD 2.3), respectively. In joinery workers cleaning was associated with a 3.0-fold higher (P < 0.001) dust concentration compared to low exposure tasks (e.g. gluing), while the use of hand tools showed 3.0- to 11.0-fold higher (P < 0.001) exposures. In furniture makers, we found a 5.4-fold higher exposure (P < 0.001) with using a table/circular saw. Laboratory efficiency experiments showed a 10-fold decrease in exposure (P < 0.001) when using a vacuum cleaner. Vacuum extraction on hand tools combined with a downdraft table reduced exposures by 42.5% for routing (P < 0.1) and 85.5% for orbital san
Published: 2017

45. Aortic Curvature Is a Predictor of Late Type Ia Endoleak and Migration after Endovascular Aneurysm Repair

Author: Schuurmann, R.C.L. (Richte C. L.), Van Noort, K. (Kim), Overeem, S.P. (Simon P.), Ouriel, K. (Kenneth), Jordan, W.D. (William D.), Muhs, B.E. (Bart), Mannetje, Y.T. (Yannick T), Reijnen, M.M.P.J. (Michel), Fioole, B. (Bram), Ünlü, Ç. (Çagdas), Brummel, P. (Peter), Vries, J.-P.P.M. (Jean-Paul) de, Schuurmann, R.C.L. (Richte C. L.), Van Noort, K. (Kim), Overeem, S.P. (Simon P.), Ouriel, K. (Kenneth), Jordan, W.D. (William D.), Muhs, B.E. (Bart), Mannetje, Y.T. (Yannick T), Reijnen, M.M.P.J. (Michel), Fioole, B. (Bram), Ünlü, Ç. (Çagdas), Brummel, P. (Peter), and Vries, J.-P.P.M. (Jean-Paul) de
Abstract: Purpose: To evaluate the association between aortic curvature and other preoperative anatomical characteristics and late (>1 year) type Ia endoleak and endograft migration in endovascular aneurysm repair (EVAR) patients. Methods: Eight high-volume EVAR centers contributed 116 EVAR patients (mean age 81±7 years; 103 men) to the study: 36 patients (mean age 82±7 years; 31 men) with endograft migration and/or type Ia endoleak diagnosed >1 year after the initial EVAR and 80 controls without early or late complications. Aortic curvature was calculated from the preoperative computed tomography scan as the maximum and average curvature over 5 predefined aortic segments: the entire infrarenal aortic neck, aneurysm sac, and the suprarenal, juxtarenal, and infrarenal aorta. Other morphological characteristics included neck length, neck diameter, mural neck calcification and thrombus, suprarenal and infrarenal angulation, and largest aneurysm sac diameter. Independent risk factors were identified using backward stepwise logistic regression. Relevant cutoff values for each of the variables in the final regression model were determined with the receiver operator characteristic curve. Results: Logistic regression identified maximum curvature over the length of the aneurysm sac (>47 m-1; p=0.023), largest aneurysm sac diameter (>56 mm; p=0.028), and mural neck thrombus (>11° circumference; p<0.001) as independent predictors of late migration and type Ia endoleak. Conclusion: Aortic curvature is a predictor for late type Ia endoleak and endograft migration after EVAR. These findings suggest that aortic curvature is a better parameter than angulation to predict post-EVAR failure and should be included as a hostile neck parameter.
Published: 2017
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46. Wood Dust in Joineries and Furniture Manufacturing: An Exposure Determinant and Intervention Study

Author: LS IRAS EEPI EXAS (Arb.hyg+bl.st.kar.), dIRAS RA-I&I RA, dIRAS RA-2, Douwes, Jeroen, Cheung, Kerry, Prezant, Bradley, Sharp, Mark, Corbin, Marine, McLean, Dave, 't Mannetje, Andrea, Schlunssen, Vivi, Sigsgaard, Torben, Kromhout, Hans, LaMontagne, Anthony D, Pearce, Neil, McGlothlin, James D, LS IRAS EEPI EXAS (Arb.hyg+bl.st.kar.), dIRAS RA-I&I RA, dIRAS RA-2, Douwes, Jeroen, Cheung, Kerry, Prezant, Bradley, Sharp, Mark, Corbin, Marine, McLean, Dave, 't Mannetje, Andrea, Schlunssen, Vivi, Sigsgaard, Torben, Kromhout, Hans, LaMontagne, Anthony D, Pearce, Neil, and McGlothlin, James D
Published: 2017

47. Patterns of cellular phone use among young people in 12 countries: Implications for RF exposure

Author: LS IRAS EEPI EXAS (Arb.hyg+bl.st.kar.), LS IRAS EEPI GRA (Gezh.risico-analyse), dIRAS RA-2, Langer, Chelsea Eastman, de Llobet Viladoms, Patricia, Dalmau-Bueno, Albert, Wiart, Joe, Goedhart, Geertje, Hours, Martine, Benke, Geza P, Bouka, Evdoxia, Bruchim, Revital, Choi, Kyung-Hwa, Eng, Amanda, Ha, Mina, Karalexi, Maria, Kiyohara, Kosuke, Kojimahara, Noriko, Krewski, Daniel, Kromhout, Hans, Lacour, Brigitte, 't Mannetje, Andrea, Maule, Milena, Migliore, Enrica, Mohipp, Charmaine, Momoli, Franco, Petridou, Eleni, Radon, Katja, Remen, Thomas, Sadetzki, Siegal, Sim, Malcolm R, Weinmann, Tobias, Vermeulen, Roel, Cardis, Elisabeth, Vrijheid, Martine, LS IRAS EEPI EXAS (Arb.hyg+bl.st.kar.), LS IRAS EEPI GRA (Gezh.risico-analyse), dIRAS RA-2, Langer, Chelsea Eastman, de Llobet Viladoms, Patricia, Dalmau-Bueno, Albert, Wiart, Joe, Goedhart, Geertje, Hours, Martine, Benke, Geza P, Bouka, Evdoxia, Bruchim, Revital, Choi, Kyung-Hwa, Eng, Amanda, Ha, Mina, Karalexi, Maria, Kiyohara, Kosuke, Kojimahara, Noriko, Krewski, Daniel, Kromhout, Hans, Lacour, Brigitte, 't Mannetje, Andrea, Maule, Milena, Migliore, Enrica, Mohipp, Charmaine, Momoli, Franco, Petridou, Eleni, Radon, Katja, Remen, Thomas, Sadetzki, Siegal, Sim, Malcolm R, Weinmann, Tobias, Vermeulen, Roel, Cardis, Elisabeth, and Vrijheid, Martine
Published: 2017

48. Wood dust in joineries and furniture manufacturing: an exposure determinant and intervention study

Author: Douwes, Jeroen, Cheung, Kerry, Prezant, Bradley, Sharp, Mark, Corbin, Marine, McLean, Dave, 't Mannetje, Andrea, Schlunssen, Vivi, Sigsgaard, Torben, Kromhout, Hans, LaMontagne, Anthony D, Pearce, Neil, McGlothlin, James D, Douwes, Jeroen, Cheung, Kerry, Prezant, Bradley, Sharp, Mark, Corbin, Marine, McLean, Dave, 't Mannetje, Andrea, Schlunssen, Vivi, Sigsgaard, Torben, Kromhout, Hans, LaMontagne, Anthony D, Pearce, Neil, and McGlothlin, James D
Published: 2017

49. Carcinogenicity of welding, molybdenum trioxide, and indium tin oxide

Author: dIRAS RA-2, LS IRAS EEPI EXAS (Arb.hyg+bl.st.kar.), Guha, Neela, Loomis, Dana, Guyton, Kathryn Z., Grosse, Yann, El Ghissassi, Fatiha, Bouvard, Véronique, Benbrahim-Tallaa, Lamia, Vilahur, Nadia, Muller, Karen, Straif, Kurt, International Agency for Research on Cancer Monograph Working Group, Hansen, J., Nersesyan, A.. K., Lavoué, J., Luce, D., Ahrens, W., Fukushima, S., Kromhout, J., Peters, Susan, 't Mannetje, A., Albin, M., Baker, M. G., Fritz, J. M., Gwinn, W. M., Lunn, R. M., Tokar, E. J., Zeidler-Erdely, P. C., dIRAS RA-2, LS IRAS EEPI EXAS (Arb.hyg+bl.st.kar.), Guha, Neela, Loomis, Dana, Guyton, Kathryn Z., Grosse, Yann, El Ghissassi, Fatiha, Bouvard, Véronique, Benbrahim-Tallaa, Lamia, Vilahur, Nadia, Muller, Karen, Straif, Kurt, International Agency for Research on Cancer Monograph Working Group, Hansen, J., Nersesyan, A.. K., Lavoué, J., Luce, D., Ahrens, W., Fukushima, S., Kromhout, J., Peters, Susan, 't Mannetje, A., Albin, M., Baker, M. G., Fritz, J. M., Gwinn, W. M., Lunn, R. M., Tokar, E. J., and Zeidler-Erdely, P. C.
Published: 2017

50. Carcinogenicity of welding, molybdenum trioxide, and indium tin oxide

Author: dIRAS RA-2, LS IRAS EEPI EXAS (Arb.hyg+bl.st.kar.), Guha, Neela, Loomis, Dana, Guyton, Kathryn Z., Grosse, Yann, El Ghissassi, Fatiha, Bouvard, Véronique, Benbrahim-Tallaa, Lamia, Vilahur, Nadia, Muller, Karen, Straif, Kurt, International Agency for Research on Cancer Monograph Working Group, Hansen, J., Nersesyan, A.. K., Lavoué, J., Luce, D., Ahrens, W., Fukushima, S., Kromhout, J., Peters, Susan, 't Mannetje, A., Albin, M., Baker, M. G., Fritz, J. M., Gwinn, W. M., Lunn, R. M., Tokar, E. J., Zeidler-Erdely, P. C., dIRAS RA-2, LS IRAS EEPI EXAS (Arb.hyg+bl.st.kar.), Guha, Neela, Loomis, Dana, Guyton, Kathryn Z., Grosse, Yann, El Ghissassi, Fatiha, Bouvard, Véronique, Benbrahim-Tallaa, Lamia, Vilahur, Nadia, Muller, Karen, Straif, Kurt, International Agency for Research on Cancer Monograph Working Group, Hansen, J., Nersesyan, A.. K., Lavoué, J., Luce, D., Ahrens, W., Fukushima, S., Kromhout, J., Peters, Susan, 't Mannetje, A., Albin, M., Baker, M. G., Fritz, J. M., Gwinn, W. M., Lunn, R. M., Tokar, E. J., and Zeidler-Erdely, P. C.
Published: 2017

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