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The Supreme Court decision in Dobbs v. Jackson in June 2022 reversed precedent which had previously protected abortion prior to fetal viability as a universal right within the United States. This decision almost immediately led to abortion restrictions across 25 states. The resulting lack of access to abortion care for millions of pregnant people will have profound physical and mental health consequences, the full effects of which will not be realized for years to come. Approximately 1 in 5 women access abortions in the U.S. each year. These women are diverse and represent all American groups. The Supreme court decision, however, will affect populations that have and continue to be marginalized the most. Forcing pregnant individuals to carry unwanted pregnancies worsens health outcomes and mortality risk for both the perinatal individual and the offspring. The US has one of the highest maternal mortality rates and this rate is projected to increase with abortion bans. Abortion policies also interfere with appropriate medical care of pregnant people leading to less safe pregnancies for all. Beyond the physical morbidity, the psychological sequelae of carrying a forced pregnancy to term will lead to an even greater burden of maternal mental illness, exacerbating the already existing maternal mental health crisis. This perspective piece reviews the current evidence of abortion denial on women's mental health and care. Based on the current evidence, we discuss the clinical, educational, societal, research, and policy implications of the Dobbs v. Jackson Supreme Court decision.

We analyze the multilayer architecture of the global input-output network using sectoral trade data (WIOD, 2016 release). With a focus on the mesoscale structure and related properties, our multilayer analysis takes into consideration the splitting into industry-based layers in order to catch more peculiar relationships between countries that cannot be detected from the analysis of the single-layer aggregated network. We can identify several large international communities in which some countries trade more intensively in some specific layers. However, interestingly, our results show that these clusters can restructure and evolve over time. In general, not only their internal composition changes, but the centrality rankings of the members inside are also reordered, industries from some countries diminishing their role and others from other countries growing importance. These changes in the large international clusters may reflect the outcomes and the dynamics of cooperation, partner selection and competition among industries and among countries in the global input-output network.

This thesis presents the design and the implementation of Oulu Traffic Simulation System (OTSS), a traffic simulation system for the City of Oulu, Finland. Following agent-based approach, the simulation generates artificial agents that represent the population synthesis of the City of Oulu. Data from several sources, including official statistics, government-organized open data and crowdsourced information were collected and used as input for the simulation. Two traffic demand models are presented in this thesis: (1) the random model which generates traffic trips as random, discrete events; and (2) the activity-based model which defines traffic trips as sequential events in the agents’ day plan. The software development of the system follows the spiral model of software development and enhancement. During the implementation, several development cycles were conducted before the UML software design. The system was executed on two computation systems to test its real-time performance. To evaluate the traffic models, data extracted from the simulation was compared with aggregated survey data from Finnish Transport Agency and traffic count stations around the city. The results showed that a typical server is capable of running the simulation, and even though there were differences in the duration and distance of individual trips, the simulation reflects real-life traffic count significantly well.

Background: Individuals with 1st degree relatives harboring an intracranial aneurysm (IA) are at an increased risk of IA, suggesting genetic variation is an important risk factor. Methods: Families with multiple members having ruptured or unruptured IA were recruited and all available medical records and imaging data were reviewed to classify possible IA subjects as definite, probable or possible IA or not a case. A 6 K SNP genome screen was performed in 333 families, representing the largest linkage study of IA reported to date. A 'narrow' (n = 705 definite IA cases) and 'broad' (n = 866 definite or probable IA) disease definition were used in multipoint model-free linkage analysis and parametric linkage analysis, maximizing disease parameters. Ordered subset analysis (OSA) was used to detect gene × smoking interaction. Results: Model-free linkage analyses detected modest evidence of possible linkage (all LOD < 1.5). Parametric analyses yielded an unadjusted LOD score of 2.6 on chromosome 4q (162 cM) and 3.1 on chromosome 12p (50 cM). Significant evidence for a gene × smoking interaction was detected using both disease models on chromosome 7p (60 cM; p ≤ 0.01). Our study provides modest evidence of possible linkage to several chromosomes. Conclusion: These data suggest it is unlikely that there is a single common variant with a strong effect in the majority of the IA families. Rather, it is likely that multiple genetic and environmental risk factors contribute to the susceptibility for intracranial aneurysms.

The Proceedings of the 2008 Antenna Applications Symposium is a collection of state-of-the art papers relating to antenna arrays, millimeter wave antennas, simulation, and measurement of antennas integrated antennas and antenna bandwidth and radiation improvements., Volume 1 of 2. Volume 2, AFRL-RY-HS-TR-2008-0026-Vol-2. Volume 1 contains pages 1-269. The original document contains color images. Presented at Proceedings of the Antenna Applications Symposium (32nd) held in Monticello, Illinois on 16-18 September 2008. See also ADA494633.

The Proceedings of the 2007 Antenna Applications Symposium is a collection of state-of-the art papers relating to antenna arrays millimeter wave antennas simulation and measurement of antennas integrated antennas and antenna bandwidth and radiation improvements., Volume 2 of 2. Volume 1, AFRL-RY-HS-TR-2008-0026-VOL-1. Volume 2 contains pages 270-524. The original document contains color images. Presented at Proceedings of the Antenna Applications Symposium (32nd) held in Monticello, Illinois on 16-18 September 2008. See also ADA494632.