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11 results on '"Kuhn N"'

1. Tunneling nanotubes and gap junctions–their role in long-range intercellular communication during development, health, and disease conditions

Author

Ariazi, J. (Jennifer), Benowitz, A. (Andrew), De Biasi, V. (Vern), Boer, M.L. (Monique) den, Cherqui, S. (Stephanie), Cui, H. (Haifeng), Douillet, N. (Nathalie), Eugenin, E.A. (Eliseo A.), Favre, D. (David), Goodman, S. (Spencer), Gousset, K. (Karine), Hanein, D. (Dorit), Israel, D.I. (David I.), Kimura, S. (Shunsuke), Kirkpatrick, R.B. (Robert B.), Kuhn, N. (Nastaran), Jeong, C. (Claire), Lou, E. (Emil), Mailliard, R. (Robbie), Maio, S. (Stephen), Okafo, G. (George), Osswald, M. (Matthias), Pasquier, J. (Jennifer), Polak, R. (Roel), Pradel, G. (Gabriele), Rooij, B. (Bob) de, Schaeffer, P. (Peter), Skeberdis, V.A. (Vytenis A.), Smith, I.F. (Ian F.), Tanveer, A. (Ahmad), Volkmann, N. (Niels), Wu, Z. (Zhenhua), Zurzolo, C. (Chiara), Ariazi, J. (Jennifer), Benowitz, A. (Andrew), De Biasi, V. (Vern), Boer, M.L. (Monique) den, Cherqui, S. (Stephanie), Cui, H. (Haifeng), Douillet, N. (Nathalie), Eugenin, E.A. (Eliseo A.), Favre, D. (David), Goodman, S. (Spencer), Gousset, K. (Karine), Hanein, D. (Dorit), Israel, D.I. (David I.), Kimura, S. (Shunsuke), Kirkpatrick, R.B. (Robert B.), Kuhn, N. (Nastaran), Jeong, C. (Claire), Lou, E. (Emil), Mailliard, R. (Robbie), Maio, S. (Stephen), Okafo, G. (George), Osswald, M. (Matthias), Pasquier, J. (Jennifer), Polak, R. (Roel), Pradel, G. (Gabriele), Rooij, B. (Bob) de, Schaeffer, P. (Peter), Skeberdis, V.A. (Vytenis A.), Smith, I.F. (Ian F.), Tanveer, A. (Ahmad), Volkmann, N. (Niels), Wu, Z. (Zhenhua), and Zurzolo, C. (Chiara)

Abstract

Cell-to-cell communication is essential for the organization, coordination, and development of cellular networks and multi-cellular systems. Intercellular communication is mediated by soluble factors (including growth factors, neurotransmitters, and cytokines/chemokines), gap junctions, exosomes and recently described tunneling nanotubes (TNTs). It is unknown whether a combination of these communication mechanisms such as TNTs and gap junctions may be important, but further research is required. TNTs are long cytoplasmic bridges that enable long-range, directed communication between connected cells. The proposed functions of TNTs are diverse and not well understood but have been shown to include the cell-to-cell transfer of vesicles, organelles, electrical stimuli and small molecules. However, the exact role of TNTs and gap junctions for intercellular communication and their impact on disease is still uncertain and thus, the subject of much debate. The combined data from numerous laboratories indicate that some TNT mediate a long-range gap junctional communication to coordinate metabolism and signaling, in relation to infectious, genetic, metabolic, cancer, and age-related diseases. This review aims to describe the current knowledge, challenges and future perspectives to characterize and explore this new intercellular communication system and to design TNT-based therapeutic strategies.

Published
2017
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2. Tunneling Nanotubes and Gap Junctions-Their Role in Long-Range Intercellular Communication during Development, Health, and Disease Conditions

Author

Ariazi, J, Benowitz, A, De Biasi, V, den Boer, Monique, Cherqui, S, Cui, HF, Douillet, N, Eugenin, EA, Favre, D, Goodman, S, Gousset, K, Hanein, D, Israel, DI, Kimura, S, Kirkpatrick, RB, Kuhn, N, Jeong, C, Lou, E, Mailliard, R, Maio, S, Okafo, G, Osswald, M, Pasquier, J, Polak, R, Pradel, G, Rooij, Bob, Schaeffer, P, Skeberdis, VA, Smith, IF, Tanveer, A, Volkmann, N, Wu, ZH, Zurzolo, C, Ariazi, J, Benowitz, A, De Biasi, V, den Boer, Monique, Cherqui, S, Cui, HF, Douillet, N, Eugenin, EA, Favre, D, Goodman, S, Gousset, K, Hanein, D, Israel, DI, Kimura, S, Kirkpatrick, RB, Kuhn, N, Jeong, C, Lou, E, Mailliard, R, Maio, S, Okafo, G, Osswald, M, Pasquier, J, Polak, R, Pradel, G, Rooij, Bob, Schaeffer, P, Skeberdis, VA, Smith, IF, Tanveer, A, Volkmann, N, Wu, ZH, and Zurzolo, C

Published
2017

7. CLIFT: a Cross-Layer InFormation Tool to perform cross-layer analysis based on real physical traces

Author

Kuhn, N., Lochin, E., Lacan, J., Boreli, R., Bes, C., Clarac, L., Kuhn, N., Lochin, E., Lacan, J., Boreli, R., Bes, C., and Clarac, L.

Abstract

Considering real physical (MAC/PHY) traces inside network simulations is a complex task that might lead to complex yet approximated models. However, realistic cross-layer analysis with the upper layer and in particular the transport layer cannot be driven without considering the MAC/PHY level. In this paper, we propose to cope with this problem by introducing a software that translates real physical events from a given trace in order to be used inside a network simulator such as $ns$-2. The main objective is to accurately perform analysis of the impact of link layer reliability schemes (obtained by the use of real physical traces) on transport layer performance. We detail the internal mechanisms and the benefits of this software with a focus on 4G satellite communications scenarios and present the resulting metrics provided by CLIFT to perform consistent cross-layer analysis.

Published
2012

10. ExoFiT: ExoMars-Like Field Trials – a Mission Simulation.

Author

Hall, A., Dobke, B., Lisle, M., Shilton, M., Allouis, E., Waugh, L., Carroll, J., Doignon, G., Azkarate, M., van Winnendael, M., Duvet, L., Martin, D., Delfa, J., Vago, J., Schwenzer, S. P., Balme, M., Fawdon, P., Turner, S., Bedford, C., Sargeant, Hannah, Pegg, D., Mirino, M., Barrett, T., Ladegaard, A., Rull, F., Veneranda, M., Bontognali, T., Josset, T., Josset, J.-L., Josset, M., Ciarletti, V., Plettemeier, D., Le Gall, A., Hervé, Y., Corbel, C., Vieau, A.-J., Oudart, N. R., Trainer, V., Benedix, W.-S., Hegler, S., Lopez, G., Saiz, J., Preston, L., Cousins, C., Allender, E., Banham, S., Barnes, R., Northwood-Smith, G., Sangwan, K., Grindrod, P., Davis, J., Motaghian, S., Dickeson, Z., Boazman, S., Schroder, C., Hauber, E., Schmitz, N., Parkes-Bowen, A., Bahir, R., Barcenilla, R., Leff, C., Persud, D., Coates, A., Griffiths, A., Stabbins, R., Bohacek, E., Kuhn, N., Westall, F., Hall, A., Dobke, B., Lisle, M., Shilton, M., Allouis, E., Waugh, L., Carroll, J., Doignon, G., Azkarate, M., van Winnendael, M., Duvet, L., Martin, D., Delfa, J., Vago, J., Schwenzer, S. P., Balme, M., Fawdon, P., Turner, S., Bedford, C., Sargeant, Hannah, Pegg, D., Mirino, M., Barrett, T., Ladegaard, A., Rull, F., Veneranda, M., Bontognali, T., Josset, T., Josset, J.-L., Josset, M., Ciarletti, V., Plettemeier, D., Le Gall, A., Hervé, Y., Corbel, C., Vieau, A.-J., Oudart, N. R., Trainer, V., Benedix, W.-S., Hegler, S., Lopez, G., Saiz, J., Preston, L., Cousins, C., Allender, E., Banham, S., Barnes, R., Northwood-Smith, G., Sangwan, K., Grindrod, P., Davis, J., Motaghian, S., Dickeson, Z., Boazman, S., Schroder, C., Hauber, E., Schmitz, N., Parkes-Bowen, A., Bahir, R., Barcenilla, R., Leff, C., Persud, D., Coates, A., Griffiths, A., Stabbins, R., Bohacek, E., Kuhn, N., and Westall, F.

11. ExoFiT: ExoMars-Like Field Trials – a Mission Simulation.

Author

Hall, A., Dobke, B., Lisle, M., Shilton, M., Allouis, E., Waugh, L., Carroll, J., Doignon, G., Azkarate, M., van Winnendael, M., Duvet, L., Martin, D., Delfa, J., Vago, J., Schwenzer, S. P., Balme, M., Fawdon, P., Turner, S., Bedford, C., Sargeant, Hannah, Pegg, D., Mirino, M., Barrett, T., Ladegaard, A., Rull, F., Veneranda, M., Bontognali, T., Josset, T., Josset, J.-L., Josset, M., Ciarletti, V., Plettemeier, D., Le Gall, A., Hervé, Y., Corbel, C., Vieau, A.-J., Oudart, N. R., Trainer, V., Benedix, W.-S., Hegler, S., Lopez, G., Saiz, J., Preston, L., Cousins, C., Allender, E., Banham, S., Barnes, R., Northwood-Smith, G., Sangwan, K., Grindrod, P., Davis, J., Motaghian, S., Dickeson, Z., Boazman, S., Schroder, C., Hauber, E., Schmitz, N., Parkes-Bowen, A., Bahir, R., Barcenilla, R., Leff, C., Persud, D., Coates, A., Griffiths, A., Stabbins, R., Bohacek, E., Kuhn, N., Westall, F., Hall, A., Dobke, B., Lisle, M., Shilton, M., Allouis, E., Waugh, L., Carroll, J., Doignon, G., Azkarate, M., van Winnendael, M., Duvet, L., Martin, D., Delfa, J., Vago, J., Schwenzer, S. P., Balme, M., Fawdon, P., Turner, S., Bedford, C., Sargeant, Hannah, Pegg, D., Mirino, M., Barrett, T., Ladegaard, A., Rull, F., Veneranda, M., Bontognali, T., Josset, T., Josset, J.-L., Josset, M., Ciarletti, V., Plettemeier, D., Le Gall, A., Hervé, Y., Corbel, C., Vieau, A.-J., Oudart, N. R., Trainer, V., Benedix, W.-S., Hegler, S., Lopez, G., Saiz, J., Preston, L., Cousins, C., Allender, E., Banham, S., Barnes, R., Northwood-Smith, G., Sangwan, K., Grindrod, P., Davis, J., Motaghian, S., Dickeson, Z., Boazman, S., Schroder, C., Hauber, E., Schmitz, N., Parkes-Bowen, A., Bahir, R., Barcenilla, R., Leff, C., Persud, D., Coates, A., Griffiths, A., Stabbins, R., Bohacek, E., Kuhn, N., and Westall, F.

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