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Intimate partner violence (IPV) is a major public health issue that is more evident in societies that are dominated by Patriarchal cultures. Some Males' alcohol may lead them to develop aggressive behaviors, and this may lead to domestic violence. The present work aims to examine the association between alcohol use and IPV in ever-married women of Pakistan. Cross-sectional data from PDHS 2017-18 was used with a sample of 171 ever-married women whose husbands consumed alcohol to determine socioeconomic and demographic factors associated with IPV. Data reveals that 61.4% of women reported experiencing intimate partner violence (IPV), with increased frequency among those in lower socioeconomic strata. Research indicated that women from lower-income households were more susceptible to violence, with those in the lowest wealth groups demonstrating markedly higher prevalence rates. The multivariate logistic regression analysis yielded adjusted odds ratios (AOR) that indicated significant findings. Women with the lowest levels of wealth were 4.93 times more likely to experience intimate partner violence compared to those with higher levels of wealth (AOR = 4.93; 95% CI: 1.13-21.47). The likelihood of intimate partner violence (IPV) was also elevated for women from families classified as middle-income (AOR = 3.63; 95% CI: 1.02-12.91) and affluent (AOR = 4.46; 95% CI: 1.12-17.71). Moreover, residing in urban areas was associated with an increased likelihood of intimate partner violence (AOR = 3.14; 95% CI: 1.42-6.93), underscoring the socio-environmental complexities of violence. Based on these findings, it is imperative to call for effective prevention and intervention programs that focus on alcohol use and IPV in Pakistan, especially amongst low-income women.

Once unimaginable, fertility management is now a nationally established part of cancer care in institutions, from academic centers to community hospitals to private practices. Over the last two decades, advances in medicine and reproductive science have made it possible for men, women and children to be connected with an oncofertility specialist or offered fertility preservation soon after a cancer diagnosis. The Oncofertility Consortium's National Physicians Cooperative is a large-scale effort to engage physicians across disciplines - oncology, urology, obstetrics and gynecology, reproductive endocrinology, and behavioral health - in clinical and research activities to enable significant progress in providing fertility preservation options to children and adults. Here, we review the structure and function of the National Physicians Cooperative and identify next steps.

Once unimaginable, fertility management is now a nationally established part of cancer care in institutions, from academic centers to community hospitals to private practices. Over the last two decades, advances in medicine and reproductive science have made it possible for men, women and children to be connected with an oncofertility specialist or offered fertility preservation soon after a cancer diagnosis. The Oncofertility Consortium's National Physicians Cooperative is a large-scale effort to engage physicians across disciplines - oncology, urology, obstetrics and gynecology, reproductive endocrinology, and behavioral health - in clinical and research activities to enable significant progress in providing fertility preservation options to children and adults. Here, we review the structure and function of the National Physicians Cooperative and identify next steps.

Asma Javed,1 Rahul Kashyap,2 Aida N Lteif1 1Pediatric and Adolescent Medicine, Division of Pediatric Endocrinology Mayo Clinic, Rochester, MN, USA; 2Department of Anesthesia and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA Objective: To compare the reproductive, metabolic, and skeletal profiles of young athletic women with functional hypothalamic amenorrhea (FHA) as well as clinical or biochemical hyperandrogenism (FHA-EX+HA) with body mass index matched women with FHA due to exercise (FHA-EX) or anorexia nervosa (FHA-AN) alone.Design: Retrospective cohort study.Setting: Tertiary care teaching hospital.Population: Adolescents and young women, 15–30 years of age, diagnosed with FHA along with concurrent signs of hyperandrogenism (n=22) and body mass index matched control groups consisting of 22 women in each group of FHA-EX and FHA-AN. Main outcomes: 1) Reproductive hormone profile: luteinizing hormone (LH), follicle stimulating hormone (FSH), total testosterone, pelvic ultrasound features. 2) Metabolic function and skeletal health markers: fasting glucose, cholesterol, number of stress fractures and bone mineral density as assessed by spine dual-energy X-ray absorptiometry z scores. Results: FHA-EX+HA group was older at diagnosis compared to the other groups with a median (interquartile range [IQR]) age of 22 (18.75–25.25) years versus (vs) 17.5 (15.75–19) for FHA-EX; (P<0.01) and 18 (16–22.25) years for FHA-AN (P=0.01). There were no differences among the groups based on number of hours of exercise per week, type of physical activity or duration of amenorrhea. Median (IQR) LH/FSH ratio was higher in FHA-EX+HA than both other groups, 1.44 (1.03–1.77) vs 0.50 (0.20–0.94) for FHA-EX and 0.67 (0.51–0.87) for FHA-AN (P<0.01 for both). Total testosterone concentrations were not different among the groups. Median (IQR) fasting serum glucose concentration was higher in FHA-EX+HA