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Astragali Radix (Huangqi) is a popular traditional Chinese medicine for Qi-deficiency and Yang-weakness. The active constituents include saponins, flavonoids and polysaccharides; however, the levels of these components vary in different sources of Astragali Radix. By using HPLC and spectrophotometry, the amounts of isoflavonoids I-V, astragalosides I-IV and total polysaccharide were determined in two Astragali Radices: Astragalus membranaceus and A. membranaceus var. mongolicus; its adulterants: A. hoantchy, A. lehmannianus, A. aksuensis and A. propinquus; and its substitute: Hedysarum polybotrys (Hedysari Radix, Hongqi). Various specimens of these plants, either cultivated or wild, from different regions of China were also analyzed for their saponin, isoflavonoid and polysaccharide contents. The results showed that the amounts of isoflavonoids I-V and astragalosides I-IV varied in different species, and in plants from different habitat regions. The chemical composition was compared between various species sources of Astragali Radix, and their quality was discussed to give useful information for the quality control of Astragali Radix.

Astragali Radix (Huangqi) is a popular traditional Chinese medicine for Qi-deficiency and Yang-weakness. The active constituents include saponins, flavonoids and polysaccharides; however, the levels of these components vary in different sources of Astragali Radix. By using HPLC and spectrophotometry, the amounts of isoflavonoids I-V, astragalosides I-IV and total polysaccharide were determined in two Astragali Radices: Astragalus membranaceus and A. membranaceus var. mongolicus; its adulterants: A. hoantchy, A. lehmannianus, A. aksuensis and A. propinquus; and its substitute: Hedysarum polybotrys (Hedysari Radix, Hongqi). Various specimens of these plants, either cultivated or wild, from different regions of China were also analyzed for their saponin, isoflavonoid and polysaccharide contents. The results showed that the amounts of isoflavonoids I-V and astragalosides I-IV varied in different species, and in plants from different habitat regions. The chemical composition was compared between various species sources of Astragali Radix, and their quality was discussed to give useful information for the quality control of Astragali Radix.

Astragali Radix (Huangqi) is a popular traditional Chinese medicine for Qi-deficiency and Yang-weakness. The active constituents include saponins, flavonoids and polysaccharides; however, the levels of these components vary in different sources of Astragali Radix. By using HPLC and spectrophotometry, the amounts of isoflavonoids I-V, astragalosides I-IV and total polysaccharide were determined in two Astragali Radices: Astragalus membranaceus and A. membranaceus var. mongolicus; its adulterants: A. hoantchy, A. lehmannianus, A. aksuensis and A. propinquus; and its substitute: Hedysarum polybotrys (Hedysari Radix, Hongqi). Various specimens of these plants, either cultivated or wild, from different regions of China were also analyzed for their saponin, isoflavonoid and polysaccharide contents. The results showed that the amounts of isoflavonoids I-V and astragalosides I-IV varied in different species, and in plants from different habitat regions. The chemical composition was compared between various species sources of Astragali Radix, and their quality was discussed to give useful information for the quality control of Astragali Radix.