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"[...] und doch scheint es dem schulischen Tramtram immer wieder zu gelingen, den Lernenden die Freude an der deutschen Sprache zu nehmen. Je länger jemand in der Schule Deutsch lernt, umso weniger gefällt ihm oder ihr diese Sprache" (167). Dies ist eine der vielen Zwischenzusammenfassungen in diesem engagierten, schwierigen und zornigen Buch Antonie Hornungs zum Schreiben. Es ist ein fulminantes Buch, eines, das die DaF-Lehrenden (in aller Welt) auffordert, nicht immer nur stur sprach- und didaktik/methodikgeleitet Schreiben zu unterrichten, sondern die eigene Sprache der Lernenden mit einzubeziehen (171).

"[...] und doch scheint es dem schulischen Tramtram immer wieder zu gelingen, den Lernenden die Freude an der deutschen Sprache zu nehmen. Je länger jemand in der Schule Deutsch lernt, umso weniger gefällt ihm oder ihr diese Sprache" (167). Dies ist eine der vielen Zwischenzusammenfassungen in diesem engagierten, schwierigen und zornigen Buch Antonie Hornungs zum Schreiben. Es ist ein fulminantes Buch, eines, das die DaF-Lehrenden (in aller Welt) auffordert, nicht immer nur stur sprach- und didaktik/methodikgeleitet Schreiben zu unterrichten, sondern die eigene Sprache der Lernenden mit einzubeziehen (171).

"[...] und doch scheint es dem schulischen Tramtram immer wieder zu gelingen, den Lernenden die Freude an der deutschen Sprache zu nehmen. Je länger jemand in der Schule Deutsch lernt, umso weniger gefällt ihm oder ihr diese Sprache" (167). Dies ist eine der vielen Zwischenzusammenfassungen in diesem engagierten, schwierigen und zornigen Buch Antonie Hornungs zum Schreiben. Es ist ein fulminantes Buch, eines, das die DaF-Lehrenden (in aller Welt) auffordert, nicht immer nur stur sprach- und didaktik/methodikgeleitet Schreiben zu unterrichten, sondern die eigene Sprache der Lernenden mit einzubeziehen (171).

Von Netscape und Floppy Disk zu »Online Religion« und digitalen Gottesdiensten – im Zuge der Digitalisierung verändert sich so einiges in unserer Gesellschaft. Doch wie wirkt sich das digitale Zeitalter konkret auf unsere Gesellschaft aus und in welcher Form müssen wir mit unserem Tun und Handeln auf die Digitalisierung reagieren? Thomas Schlag spricht im Interview über die Notwendigkeit von asketischen, schlanken und elementaren Design, das »entschleunigt« und »still hält«, um der Flut der heutigen Medien entgegen zu wirken. Design als eine Art »Vermittlungsmedium«, das in Zukunft noch partizipativer zu gestalten ist und seine Zielgruppe zu Mitgestaltern macht – »sicherlich ein spannender Prozess«, den Designer da vor sich haben.

An interview in two sessions, June and July 2014, with Hans Georg Hornung, Clarence L. Johnson Professor of Aeronautics, emeritus, in the Division of Engineering and Applied Science. Dr. Hornung describes the origins of the German Templer Colony in Palestine and his upbringing there before and during World War II. Family moves to Templer settlement, Melbourne, Australia, 1948. He attends technical college; University of Melbourne; master’s in engineering, 1962. Researcher, Aeronautical Research Laboratories, Melbourne; PhD, Imperial College, London, 1965. He recalls his academic career at the Australian National University, Canberra (1967-1980); his interest in hypersonics; building free-piston shock tunnel with Raymond Stalker. Sabbatical in Darmstadt with Ernst Becker. Seven years as director of fluid-mechanics institute of the DLR [Deutsches Zentrum für Luft- und Raumfahrt], in Göttingen. Comes to Caltech in 1987 to succeed Hans W. Liepmann as director of GALCIT [Graduate Aerospace Laboratories, California Institute of Technology]. Recalls his various aero colleagues, his work with Rocketdyne on Caltech’s T5 (successor to Canberra’s T3 shock tunnel) and Ludwieg tube, collaboration with JPL on space program, and work with graduate students Simon Sanderson and Eric Cummings. Discusses his involvement in various scientific societies and his current activities and continuing research as an emeritus professor.

An interview in two sessions, June and July 2014, with Hans Georg Hornung, Clarence L. Johnson Professor of Aeronautics, emeritus, in the Division of Engineering and Applied Science. Dr. Hornung describes the origins of the German Templer Colony in Palestine and his upbringing there before and during World War II. Family moves to Templer settlement, Melbourne, Australia, 1948. He attends technical college; University of Melbourne; master’s in engineering, 1962. Researcher, Aeronautical Research Laboratories, Melbourne; PhD, Imperial College, London, 1965. He recalls his academic career at the Australian National University, Canberra (1967-1980); his interest in hypersonics; building free-piston shock tunnel with Raymond Stalker. Sabbatical in Darmstadt with Ernst Becker. Seven years as director of fluid-mechanics institute of the DLR [Deutsches Zentrum für Luft- und Raumfahrt], in Göttingen. Comes to Caltech in 1987 to succeed Hans W. Liepmann as director of GALCIT [Graduate Aerospace Laboratories, California Institute of Technology]. Recalls his various aero colleagues, his work with Rocketdyne on Caltech’s T5 (successor to Canberra’s T3 shock tunnel) and Ludwieg tube, collaboration with JPL on space program, and work with graduate students Simon Sanderson and Eric Cummings. Discusses his involvement in various scientific societies and his current activities and continuing research as an emeritus professor.

An interview in two sessions, June and July 2014, with Hans Georg Hornung, Clarence L. Johnson Professor of Aeronautics, emeritus, in the Division of Engineering and Applied Science. Dr. Hornung describes the origins of the German Templer Colony in Palestine and his upbringing there before and during World War II. Family moves to Templer settlement, Melbourne, Australia, 1948. He attends technical college; University of Melbourne; master’s in engineering, 1962. Researcher, Aeronautical Research Laboratories, Melbourne; PhD, Imperial College, London, 1965. He recalls his academic career at the Australian National University, Canberra (1967-1980); his interest in hypersonics; building free-piston shock tunnel with Raymond Stalker. Sabbatical in Darmstadt with Ernst Becker. Seven years as director of fluid-mechanics institute of the DLR [Deutsches Zentrum für Luft- und Raumfahrt], in Göttingen. Comes to Caltech in 1987 to succeed Hans W. Liepmann as director of GALCIT [Graduate Aerospace Laboratories, California Institute of Technology]. Recalls his various aero colleagues, his work with Rocketdyne on Caltech’s T5 (successor to Canberra’s T3 shock tunnel) and Ludwieg tube, collaboration with JPL on space program, and work with graduate students Simon Sanderson and Eric Cummings. Discusses his involvement in various scientific societies and his current activities and continuing research as an emeritus professor.

An interview in two sessions, June and July 2014, with Hans Georg Hornung, Clarence L. Johnson Professor of Aeronautics, emeritus, in the Division of Engineering and Applied Science. Dr. Hornung describes the origins of the German Templer Colony in Palestine and his upbringing there before and during World War II. Family moves to Templer settlement, Melbourne, Australia, 1948. He attends technical college; University of Melbourne; master’s in engineering, 1962. Researcher, Aeronautical Research Laboratories, Melbourne; PhD, Imperial College, London, 1965. He recalls his academic career at the Australian National University, Canberra (1967-1980); his interest in hypersonics; building free-piston shock tunnel with Raymond Stalker. Sabbatical in Darmstadt with Ernst Becker. Seven years as director of fluid-mechanics institute of the DLR [Deutsches Zentrum für Luft- und Raumfahrt], in Göttingen. Comes to Caltech in 1987 to succeed Hans W. Liepmann as director of GALCIT [Graduate Aerospace Laboratories, California Institute of Technology]. Recalls his various aero colleagues, his work with Rocketdyne on Caltech’s T5 (successor to Canberra’s T3 shock tunnel) and Ludwieg tube, collaboration with JPL on space program, and work with graduate students Simon Sanderson and Eric Cummings. Discusses his involvement in various scientific societies and his current activities and continuing research as an emeritus professor.

The species Chrysallida maiae (Hornung & Mermod, 1924) is one of the better known Indo-Pacific migrants into the Mediterranean. It was mentioned first by van Aartsen (1963: 1116) from the coast of Israel and later on by Barash & Danin (1977: 96, 111 fig. 11). In 1958 it was found in Iskenderun (Turkey) and today it is one of the most common Pyramidellidae in the eastern Mediterranean. Nordsieck (1973: 245, 243 fig. 66) described it as Dunkeria scalaris dentata n. subspec. as could be determined from the types in the Nordsieck collection (Senkenberg Museum).

In his article "Chinese Ideas and American Politics: Confucius as a Guideline for Leadership", Alfred Hornung traces the influence of Chinese ideas on American politics with a focus on the works of Confucius. The more than 2.500-year-old impact of the Chinese philosopher on public conduct and his pursuit of virtuous perfection has served as a guideline for leadership emanating from China to Europe and America. For this trajectory of ideas, the historic and the new Silk Road play a decisive role. The exchange of goods along the land-based and maritime routes, which inform Xi Jinping's Belt and Road Initiative, also involved an exchange of cultural ideas, reflected in Marco Polo's thirteenth-century account of his trip and the Jesuits' Latin translations of Confucius. The publication of Confucius Sinarum Philosophus in Paris in 1687 made the Chinese philosopher a major source of knowledge for Europeans and turned him into "the patron saint of the eighteenth-century Enlightenment." It is the transcultural impetus of Benjamin Franklin, who reviewed Confucius' teachings in his Pennsylvania Gazette in 1737, to apply his ideas to the foundation of the American Republic. Likewise, the Founding Fathers and American presidents John Adams, Thomas Jefferson and James Madison were familiar with Confucius' moral stance for leadership, shared his rejection of corrupt regimes and promised the pursuit of happiness for all. The Confucian influence on the moral constitution of the United States of America is an important topic in the modernist poetry of Ezra Pound who takes up the history of the Chinese civilization and Confucius' role for the political formation of his country in his Cantos. It is also visible in the choice of Confucius as one of three lawgivers who figure on the eastern pediment of the 1935 US Supreme Court building in Washington, D.C. China's reconnection with the legacy of its major philosopher in 1989 becomes part of the public diplomacy to promote Chinese langua

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Thermal Management Systems (TMS) for future aircraft were investigated due to the increased expected waste heat of novel propulsion systems such as (hybrid) electric powertrains. With computational component models, the impact of different TMS on the aircraft was quantified mainly through its mass, drag and required power. Finally, the use of simplified substitute models to incorporate detailed TMS results in the conceptual aircraft design phase was demonstrated., Wärmemanagementsysteme (WMS) für zukünftige Flugzeuge wurden aufgrund des erwarteten steigenden Kühlbedarfs von zukünftigen Antriebssystemen wie z.B. hybrid elektrischen Antriebssträngen untersucht. Mithilfe von numerischen Komponentenmodellen wurde der Einfluss des WMS auf das Flugzeug durch seine Masse, seinen Widerstand und seine Leistung quantifiziert. Die Erstellung und Nutzung von Ersatzmodellen zur Integration der WMS Modelle in den konzeptionellen Flugzeugentwurf wurde demonstriert.

This thesis presents research of Urban Air Mobility infrastructure focusing on vertiports. Through means of Agent-Based Modeling and Simulation, the design drivers of airfield operations were identified and quantified. These are peak-hour demand, imbalances between arrivals and departures, number of pads and gates, approach/departure time, and boarding time. Lastly, through simulation studies, a design heuristic was created to aid vertiport layout planning., Diese Arbeit untersucht die Infrastruktur städtischer Luftmobilität mit Fokus auf Landeplätzen für Flugtaxis. Hierfür wurden durch Agenten-basierte Simulation die Treiber des Flugfeldbetriebes identifiziert. Diese umfassen den Durchsatz in der Spitzenstunde, Ungleichgewichte zwischen Starts und Landungen, Anzahl von Landeplätzen und Flugsteigen, An- und Abflugzeiten sowie die Einstiegszeit von Passagieren. Durch Simulationsstudien wurde eine Entwurfsheuristik entwickelt mit dem Ziel die Flugfeldplanung zu erleichtern.

Issue introduction by the editor in chief of the Journal of Transnational American Studies

Background: Angioedema is a rare but potentially life-threatening adverse drug reaction in patients receiving angiotensin-converting enzyme inhibitors (ACEis). Research suggests that susceptibility to ACEi-induced angioedema (ACEi-AE) involves both genetic and nongenetic risk factors. Genome- and exome-wide studies of ACEi-AE have identified the first genetic risk loci. However, understanding of the underlying pathophysiology remains limited. Objective: We sought to identify further genetic factors of ACEi-AE to eventually gain a deeper understanding of its pathophysiology. Methods: By combining data from 8 cohorts, a genome-wide association study meta-analysis was performed in more than 1000 European patients with ACEi-AE. Secondary bioinformatic analyses were conducted to fine-map associated loci, identify relevant genes and pathways, and assess the genetic overlap between ACEi-AE and other traits. Finally, an exploratory cross-ancestry analysis was performed to assess shared genetic factors in European and African-American patients with ACEi-AE. Results: Three genome-wide significant risk loci were identified. One of these, located on chromosome 20q11.22, has not been implicated previously in ACEi-AE. Integrative secondary analyses highlighted previously reported genes (BDKRB2 [bradykinin receptor B2] and F5 [coagulation factor 5]) as well as biologically plausible novel candidate genes (PROCR [protein C receptor] and EDEM2 [endoplasmic reticulum degradation enhancing alpha-mannosidase like protein 2]). Lead variants at the risk loci were found with similar effect sizes and directions in an African-American cohort. Conclusions: The present results contributed to a deeper understanding of the pathophysiology of ACEi-AE by (1) providing further evidence for the involvement of bradykinin signaling and coagulation pathways and (2) suggesting, for the first time, the involvement of the fibrinolysis pathway in this adverse drug reaction. An exploratory cross-ancestr

Background: Single-cell sequencing techniques are revolutionizing every field of biology by providing the ability to measure the abundance of biological molecules at a single-cell resolution. Although single-cell sequencing approaches have been developed for several molecular modalities, single-cell transcriptome sequencing is the most prevalent and widely applied technique. SPLiT-seq (split-pool ligation-based transcriptome sequencing) is one of these single-cell transcriptome techniques that applies a unique combinatorial-barcoding approach by splitting and pooling cells into multi-well plates containing barcodes. This unique approach required the development of dedicated computational tools to preprocess the data and extract the count matrices. Here we compare eight bioinformatic pipelines (alevin-fry splitp, LR-splitpipe, SCSit, splitpipe, splitpipeline, SPLiTseq-demultiplex, STARsolo and zUMI) that have been developed to process SPLiT-seq data. We provide an overview of the tools, their computational performance, functionality and impact on downstream processing of the single-cell data, which vary greatly depending on the tool used. Results: We show that STARsolo, splitpipe and alevin-fry splitp can all handle large amount of data within reasonable time. In contrast, the other five pipelines are slow when handling large datasets. When using smaller dataset, cell barcode results are similar with the exception of SPLiTseq-demultiplex and splitpipeline. LR-splitpipe that is originally designed for processing long-read sequencing data is the slowest of all pipelines. Alevin-fry produced different down-stream results that are difficult to interpret. STARsolo functions nearly identical to splitpipe and produce results that are highly similar to each other. However, STARsolo lacks the function to collapse random hexamer reads for which some additional coding is required. Conclusion: Our comprehensive comparati

Background: Angioedema is a rare but potentially life-threatening adverse drug reaction in patients receiving angiotensin-converting enzyme inhibitors (ACEis). Research suggests that susceptibility to ACEi-induced angioedema (ACEi-AE) involves both genetic and nongenetic risk factors. Genome- and exome-wide studies of ACEi-AE have identified the first genetic risk loci. However, understanding of the underlying pathophysiology remains limited. Objective: We sought to identify further genetic factors of ACEi-AE to eventually gain a deeper understanding of its pathophysiology. Methods: By combining data from 8 cohorts, a genome-wide association study meta-analysis was performed in more than 1000 European patients with ACEi-AE. Secondary bioinformatic analyses were conducted to fine-map associated loci, identify relevant genes and pathways, and assess the genetic overlap between ACEi-AE and other traits. Finally, an exploratory cross-ancestry analysis was performed to assess shared genetic factors in European and African-American patients with ACEi-AE. Results: Three genome-wide significant risk loci were identified. One of these, located on chromosome 20q11.22, has not been implicated previously in ACEi-AE. Integrative secondary analyses highlighted previously reported genes (BDKRB2 [bradykinin receptor B2] and F5 [coagulation factor 5]) as well as biologically plausible novel candidate genes (PROCR [protein C receptor] and EDEM2 [endoplasmic reticulum degradation enhancing alpha-mannosidase like protein 2]). Lead variants at the risk loci were found with similar effect sizes and directions in an African-American cohort. Conclusions: The present results contributed to a deeper understanding of the pathophysiology of ACEi-AE by (1) providing further evidence for the involvement of bradykinin signaling and coagulation pathways and (2) suggesting, for the first time, the involvement of the fibrinolysis pathway in this adverse drug reaction. An exploratory cross-ancestr

For applications like surveillance or cargo transport, unmanned fixed-wing aircraft with vertical takeoff and landing capability are preferred over multirotor drones because they offer higher ranges, flight times and speeds. Thus, eleven fully electric representatives of this hybrid aircraft type are compared for performance and cost using a multidisciplinary conceptual aircraft design and optimization tool chain. Further, solutions for aircraft type specific issues like low drag stopped rotor storage and hybrid battery architectures are proposed and evaluated., Für Aufgaben wie Luftaufklärung oder Frachttransport werden unbemannte, senkrechtstartfähige Tragflächenflugzeuge gegenüber Multirotordrohnen bevorzugt, da sie höhere Reichweiten, Flugzeiten und Geschwindigkeiten bieten. Daher werden elf vollelektrische Vertreter dieses hybriden Flugzeugtyps mit einer multidisziplinären Flugzeugentwurfstoolkette auf Flugleistung und Kosten verglichen. Weiter werden Lösungen für flugzeugtypspezifische Probleme vorgeschlagen, wie z. B. für die Widerstandsreduktion gestoppter Rotoren und hybride Batteriearchitekturen.

Assisted by Caroline Cassidy, piano.; This recital is presented in partial fulfillment of the requirements for the degree Master of Music., Series XXX, Number 283., This archival material has been provided for educational purposes. Ball State University Libraries recognizes that some historic items may include offensive content. Our statement regarding objectionable content is available at: https://dmr.bsu.edu/digital/about

Assisted by Caroline Cassidy, piano.; This recital is presented in partial fulfillment of the requirements for the degree Master of Music., Series XXX, Number 283., This archival material has been provided for educational purposes. Ball State University Libraries recognizes that some historic items may include offensive content. Our statement regarding objectionable content is available at: https://dmr.bsu.edu/digital/about

Signaturformel: A4, B2, Vorlageform des Erscheinungsvermerks: (Gedruckt zu Wittem||berg durch Nickel || Schirlentz.|| Ym Jar.|| M.D.XXX.||)

Signaturformel: A4, B2, Vorlageform des Erscheinungsvermerks: (Gedruckt zu Wittem||berg durch Nickel || Schirlentz.|| Ym Jar.|| M.D.XXX.||)

Collection : Collection Morari, Collection : Collection Morari, Contient une table des matières, Avec mode texte

Collection : Collection Morari, Collection : Collection Morari, Contient une table des matières, Avec mode texte

Comprend : CANTIQUE 319 - PSAUME 42 - PSAUME 25 - CANTIQUE 372 - CANTIQUE 370 - PSAUME 97, BnF-Partenariats, Collection sonore - Believe, Contient une table des matières