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WiFi human sensing is highly regarded for its low-cost and privacy advantages in recognizing human activities. However, its effectiveness is largely confined to controlled, single-user, line-of-sight settings, limited by data collection complexities and the scarcity of labeled datasets. Traditional cross-modal methods, aimed at mitigating these limitations by enabling self-supervised learning without labeled data, struggle to extract meaningful features from amplitude-phase combinations. In response, we introduce AutoSen, an innovative automatic WiFi sensing solution that departs from conventional approaches. AutoSen establishes a direct link between amplitude and phase through automated cross-modal autoencoder learning. This autoencoder efficiently extracts valuable features from unlabeled CSI data, encompassing amplitude and phase information while eliminating their respective unique noises. These features are then leveraged for specific tasks using few-shot learning techniques. AutoSen's performance is rigorously evaluated on a publicly accessible benchmark dataset, demonstrating its exceptional capabilities in automatic WiFi sensing through the extraction of comprehensive cross-modal features.

WiFi-based human action recognition (HAR) has been regarded as a promising solution in applications such as smart living and remote monitoring due to the pervasive and unobtrusive nature of WiFi signals. However, the efficacy of WiFi signals is prone to be influenced by the change in the ambient environment and varies over different sub-carriers. To remedy this issue, we propose an end-to-end Gabor residual anti-aliasing sensing network (GraSens) to directly recognize the actions using the WiFi signals from the wireless devices in diverse scenarios. In particular, a new Gabor residual block is designed to address the impact of the changing surrounding environment with a focus on learning reliable and robust temporal-frequency representations of WiFi signals. In each block, the Gabor layer is integrated with the anti-aliasing layer in a residual manner to gain the shift-invariant features. Furthermore, fractal temporal and frequency self-attention are proposed in a joint effort to explicitly concentrate on the efficacy of WiFi signals and thus enhance the quality of output features scattered in different subcarriers. Experimental results throughout our wireless-vision action recognition dataset (WVAR) and three public datasets demonstrate that our proposed GraSens scheme outperforms state-of-the-art methods with respect to recognition accuracy.

Human Activity Recognition (HAR) has recently received remarkable attention in numerous applications such as assisted living and remote monitoring. Existing solutions based on sensors and vision technologies have obtained achievements but still suffering from considerable limitations in the environmental requirement. Wireless signals like WiFi-based sensing have emerged as a new paradigm since it is convenient and not restricted in the environment. In this paper, a new WiFi-based and video-based neural network (WiNN) is proposed to improve the robustness of activity recognition where the synchronized video serves as the supplement for the wireless data. Moreover, a wireless-vision benchmark (WiVi) is collected for 9 class actions recognition in three different visual conditions, including the scenes without occlusion, with partial occlusion, and with full occlusion. Both machine learning methods - support vector machine (SVM) as well as deep learning methods are used for the accuracy verification of the data set. Our results show that WiVi data set satisfies the primary demand and all three branches in the proposed pipeline keep more than $80\%$ of activity recognition accuracy over multiple action segmentation from 1s to 3s. In particular, WiNN is the most robust method in terms of all the actions on three action segmentation compared to the others.

WiFi-based sensing for human activity recognition (HAR) has recently become a hot topic as it brings great benefits when compared with video-based HAR, such as eliminating the demands of line-of-sight (LOS) and preserving privacy. Making the WiFi signals to 'see' the action, however, is quite coarse and thus still in its infancy. An end-to-end spatiotemporal WiFi signal neural network (STWNN) is proposed to enable WiFi-only sensing in both line-of-sight and non-line-of-sight scenarios. Especially, the 3D convolution module is able to explore the spatiotemporal continuity of WiFi signals, and the feature self-attention module can explicitly maintain dominant features. In addition, a novel 3D representation for WiFi signals is designed to preserve multi-scale spatiotemporal information. Furthermore, a small wireless-vision dataset (WVAR) is synchronously collected to extend the potential of STWNN to 'see' through occlusions. Quantitative and qualitative results on WVAR and the other three public benchmark datasets demonstrate the effectiveness of our approach on both accuracy and shift consistency.

Objective: Patients with renal failure suffer from symptoms caused by uraemic toxins, possibly of gut microbial origin, as deduced from studies in animals. The aim of the study is to characterise relationships between the intestinal microbiome composition, uraemic toxins and renal failure symptoms in human end-stage renal disease (ESRD). Design: Characterisation of gut microbiome, serum and faecal metabolome and human phenotypes in a cohort of 223 patients with ESRD and 69 healthy controls. Multidimensional data integration to reveal links between these datasets and the use of chronic kidney disease (CKD) rodent models to test the effects of intestinal microbiome on toxin accumulation and disease severity. Results: A group of microbial species enriched in ESRD correlates tightly to patient clinical variables and encode functions involved in toxin and secondary bile acids synthesis; the relative abundance of the microbial functions correlates with the serum or faecal concentrations of these metabolites. Microbiota from patients transplanted to renal injured germ-free mice or antibiotic-Treated rats induce higher production of serum uraemic toxins and aggravated renal fibrosis and oxidative stress more than microbiota from controls. Two of the species, Eggerthella lenta and Fusobacterium nucleatum, increase uraemic toxins production and promote renal disease development in a CKD rat model. A probiotic Bifidobacterium animalis decreases abundance of these species, reduces levels of toxins and the severity of the disease in rats. Conclusion: Aberrant gut microbiota in patients with ESRD sculpts a detrimental metabolome aggravating clinical outcomes, suggesting that the gut microbiota will be a promising target for diminishing uraemic toxicity in those patients. Trial registration number: This study was registered at ClinicalTrials.gov (NCT03010696).

Objective: Patients with renal failure suffer from symptoms caused by uraemic toxins, possibly of gut microbial origin, as deduced from studies in animals. The aim of the study is to characterise relationships between the intestinal microbiome composition, uraemic toxins and renal failure symptoms in human end-stage renal disease (ESRD). Design: Characterisation of gut microbiome, serum and faecal metabolome and human phenotypes in a cohort of 223 patients with ESRD and 69 healthy controls. Multidimensional data integration to reveal links between these datasets and the use of chronic kidney disease (CKD) rodent models to test the effects of intestinal microbiome on toxin accumulation and disease severity. Results: A group of microbial species enriched in ESRD correlates tightly to patient clinical variables and encode functions involved in toxin and secondary bile acids synthesis; the relative abundance of the microbial functions correlates with the serum or faecal concentrations of these metabolites. Microbiota from patients transplanted to renal injured germ-free mice or antibiotic-Treated rats induce higher production of serum uraemic toxins and aggravated renal fibrosis and oxidative stress more than microbiota from controls. Two of the species, Eggerthella lenta and Fusobacterium nucleatum, increase uraemic toxins production and promote renal disease development in a CKD rat model. A probiotic Bifidobacterium animalis decreases abundance of these species, reduces levels of toxins and the severity of the disease in rats. Conclusion: Aberrant gut microbiota in patients with ESRD sculpts a detrimental metabolome aggravating clinical outcomes, suggesting that the gut microbiota will be a promising target for diminishing uraemic toxicity in those patients. Trial registration number: This study was registered at ClinicalTrials.gov (NCT03010696).

Luminescent nanomaterials, with wide applications in biosensing, bioimaging, illumination and display techniques, have been consistently garnering enormous research attention. In particular, those with wavelength-controllable emissions could be highly beneficial. Carbon nanostructures, including graphene quantum dots (GQDs) and other graphene oxide derivates (GODs), with excitation-dependent photoluminescence (PL), which means their fluorescence color could be tuned simply by changing the excitation wavelength, have attracted lots of interest. However the intrinsic mechanism for the excitation-dependent PL is still obscure and fiercely debated presently. In this review, we attempt to summarize the latest efforts to explore the mechanism, including the quantum confinement effect, surface traps model, giant red-edge effect, edge states model and electronegativity of heteroatom model, as well as the newly developed synergistic model, to seek some clues to unravel the mechanism. Meanwhile the controversial difficulties for each model are further discussed. Besides this, the challenges and potential influences of the synthetic methodology and development of the materials are illustrated extensively to elicit more thought and constructive attempts toward their application., QC 20160513

Lactobacillus rhamnosus GG is a lactic acid bacterium widely marketed by the food industry. Its genomic analysis led to the identification of a gene cluster encoding mucus-binding SpaCBA pili, which is located in a genomic island enriched in insertion sequence (IS) elements. In the present study, we analyzed by genome-wide resequencing the genomic integrity of L. rhamnosus GG in four distinct evolutionary experiments conducted for approximately 1,000 generations under conditions of no stress or salt, bile, and repetitive-shearing stress. Under both stress-free and salt-induced stress conditions, the GG population (excluding the mutator lineage in the stress-free series [see below]) accumulated only a few single nucleotide polymorphisms (SNPs) and no frequent chromosomal rearrangements. In contrast, in the presence of bile salts or repetitive shearing stress, some IS elements were found to be activated, resulting in the deletion of large chromosomal segments that include the spaCBA-srtC1 pilus gene cluster. Remarkably, a high number of SNPs were found in three strains obtained after 900 generations of stress-free growth. Detailed analysis showed that these three strains derived from a founder mutant with an altered DNA polymerase subunit that resulted in a mutator phenotype. The present work confirms the stability of the pilus production phenotype in L. rhamnosus GG under stress-free conditions, highlights the possible evolutionary scenarios that may occur when this probiotic strain is extensively cultured, and identifies external factors that affect the chromosomal integrity of GG. The results provide mechanistic insights into the stability of GG in regard to its extensive use in probiotic and other functional food products.