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19 results on '"Haberstroh J"'

1. Huosi und Husibald. Tradition, Interferenz und Kommunikation mit Namen

Author

Haberstroh, Jochen, Heitmeier, Irmtraut, Haberstroh, J ( Jochen ), Heitmeier, I ( Irmtraut ), Rübekeil, Ludwig; https://orcid.org/0000-0001-7331-7517, Haberstroh, Jochen, Heitmeier, Irmtraut, Haberstroh, J ( Jochen ), Heitmeier, I ( Irmtraut ), and Rübekeil, Ludwig; https://orcid.org/0000-0001-7331-7517

Published
2019

8. Determination of respiratory system mechanics during inspiration and expiration by FLow-controlled EXpiration (FLEX) : a pilot study in anesthetized pigs

Author

Schumann, S., Goebel, U., Haberstroh, J., Vimlati, Laszlo, Schneider, M., Lichtwarck-Aschoff, Michael, Guttmann, J., Schumann, S., Goebel, U., Haberstroh, J., Vimlati, Laszlo, Schneider, M., Lichtwarck-Aschoff, Michael, and Guttmann, J.

Abstract

Background. Differences between inspiratory and expiratory lung mechanics result in the hysteresis of the pressure volume-loop. While hysteresis area is a global parameter describing the difference between inspiration and expiration in mechanics under quasi-static conditions, a detailed analysis of this difference under the dynamic conditions of mechanical ventilation is feasible once inspiratory and expiratory compliance (C-in/C-ex) are determined separately. This requires uncoupling of expiratory flow rate and volume (V). Methods. Five piglets were mechanically ventilated at positive end-expiratory pressure (PEEP) levels ranging from 0 to 15 cmH(2)O. Expiratory flow rate was linearized by a computer-controlled resistor (flow-controlled expiration). The volume-dependent C-in(V) and C-ex(V) profiles were calculated from the tracheal pressure volume-loops. Results. The intratidal curve-progression of C-ex(V) was altogether higher with a steeper slope compared to C-in(V). With increasing positive end-expiratory pressure (PEEP) dynamic hysteresis area decreased and C-ex(V) tended to run more parallel to C-in(V), Conclusion. The relation between inspiratory and expiratory compliance profiles is associated with the hysteresis area and behaves PEEP dependent. Analysing the C-in-C-ex-relation might therefore potentially offer a new approach to titrate PEEP and tidal volume.

Published
2014

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