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Ex vivo organ perfusion is a technique that aims to increase the amount of organ donors by treating an otherwise nonfunctional organ with a perfusion fluid outside of the body to restore its function. UGLK Science is an ex vivo organ perfusion company outside of Lund specializing in kidney transplantation. The organ is perfused in a machine which restores kidney function, allowing the organ to survive longer outside of the body. The tube for circulation of fluid in the system pumps the fluid upwards over the edge of the container. However, this causes air bubbles to form which have to be removed in order for the system to proceed without interruption. The presented project has therefore been carried out in collaboration with UGLK Science with the aim of developing a possible outlet located at the bottom of the container, maintaining a safe flow through a sterile barrier below the waterline. Risk analysis, fluid flow simulations and a literature study were performed in order to evaluate potential solutions. This resulted in a prototype and a specification of requirements. The requirements included, among other things, that the outlet must be biocompatible with blood, not affect the flow and allow emptying of the fluid. The final idea was a silicone-based, external outlet designed similarly to a funnel. The rounded edge of the outlet was inspired by a V-ring seal, which enables a geometric attachment to the container. The solution meets all criteria in the specification of requirements and enables a safe flow over the sterile barrier. A fully developed product based on the presented prototype of the outlet could facilitate UGLK Sciences' work and in the long run contribute to an increased number of available kidney donors.

Classification of similar looking handwritten characters in Indian languages is challenging. Especially in the case of Malayalam, a Dravidian language from the Brahmic script which is characterized by its highly curvy and looped nature.  So by considering such a nature of the language, a new feature extraction method in the field of HCR (Handwritten Character Recognition) named as Angular Method is used by using fuzzy logic classifiers with k –NN algorithm.

Classification of similar looking handwritten characters in Indian languages is challenging. Especially in the case of Malayalam, a Dravidian language from the Brahmic script which is characterized by its highly curvy and looped nature.  So by considering such a nature of the language, a new feature extraction method in the field of HCR (Handwritten Character Recognition) named as Angular Method is used by using fuzzy logic classifiers with k –NN algorithm.

Classification of similar looking handwritten characters in Indian languages is challenging. Especially in the case of Malayalam, a Dravidian language from the Brahmic script which is characterized by its highly curvy and looped nature.  So by considering such a nature of the language, a new feature extraction method in the field of HCR (Handwritten Character Recognition) named as Angular Method is used by using fuzzy logic classifiers with k –NN algorithm.

Classification of similar looking handwritten characters in Indian languages is challenging. Especially in the case of Malayalam, a Dravidian language from the Brahmic script which is characterized by its highly curvy and looped nature.  So by considering such a nature of the language, a new feature extraction method in the field of HCR (Handwritten Character Recognition) named as Angular Method is used by using fuzzy logic classifiers with k –NN algorithm.

Classification of similar looking handwritten characters in Indian languages is challenging. Especially in the case of Malayalam, a Dravidian language from the Brahmic script which is characterized by its highly curvy and looped nature.  So by considering such a nature of the language, a new feature extraction method in the field of HCR (Handwritten Character Recognition) named as Angular Method is used by using fuzzy logic classifiers with k –NN algorithm.

Classification of similar looking handwritten characters in Indian languages is challenging. Especially in the case of Malayalam, a Dravidian language from the Brahmic script which is characterized by its highly curvy and looped nature.  So by considering such a nature of the language, a new feature extraction method in the field of HCR (Handwritten Character Recognition) named as Angular Method is used by using fuzzy logic classifiers with k –NN algorithm.

Classification of similar looking handwritten characters in Indian languages is challenging. Especially in the case of Malayalam, a Dravidian language from the Brahmic script which is characterized by its highly curvy and looped nature.  So by considering such a nature of the language, a new feature extraction method in the field of HCR (Handwritten Character Recognition) named as Angular Method is used by using fuzzy logic classifiers with k –NN algorithm.

info:eu-repo/semantics/published

Presentaciones utilizadas para la impartición de la asignatura de Presas en el Grado de Ingeniería Fluvial, curso 2013-2014, Universidad de Alicante.

Presentaciones utilizadas para la impartición de la asignatura de Presas en el Grado de Ingeniería Fluvial, curso 2013-2014, Universidad de Alicante.

The PSORS1 locus in the major histocompatibility complex region is the major genetic determinant for psoriasis vulgaris. Within the PSORS1 region reside at least three potential candidate genes for psoriasis susceptibility. Specific allelic variants of the genes HLA-Cw*6, HCR*WWCC, and CDSN*5 are strongly associated with psoriasis vulgaris and are in strong linkage disequilibrium with each other. We have genotyped the three psoriasis vulgaris susceptibility alleles of the PSORS1 locus in two clinical variants of psoriasis (guttate psoriasis and palmoplantar pustulosis) to study whether PSORS1 is also involved in the pathogenesis of these variants. We also asked whether these two clinical subgroups could help us to distinguish the causative gene within the high-risk PSORS1 haplotype. The association of guttate psoriasis with the three PSORS1 susceptibility alleles was similar and even stronger than seen with psoriasis vulgaris. Palmoplantar pustulosis, however, did not show association with any of the three candidate genes at this locus. Finally, no correlation with the age of onset for disease was observed. Our results show conclusively that psoriasis vulgaris and guttate psoriasis have a similar genetic basis for their association to PSORS1, whereas palmoplantar pustulosis appears to be a distinct disorder.

The PSORS1 locus in the major histocompatibility complex region is the major genetic determinant for psoriasis vulgaris. Within the PSORS1 region reside at least three potential candidate genes for psoriasis susceptibility. Specific allelic variants of the genes HLA-Cw*6, HCR*WWCC, and CDSN*5 are strongly associated with psoriasis vulgaris and are in strong linkage disequilibrium with each other. We have genotyped the three psoriasis vulgaris susceptibility alleles of the PSORS1 locus in two clinical variants of psoriasis (guttate psoriasis and palmoplantar pustulosis) to study whether PSORS1 is also involved in the pathogenesis of these variants. We also asked whether these two clinical subgroups could help us to distinguish the causative gene within the high-risk PSORS1 haplotype. The association of guttate psoriasis with the three PSORS1 susceptibility alleles was similar and even stronger than seen with psoriasis vulgaris. Palmoplantar pustulosis, however, did not show association with any of the three candidate genes at this locus. Finally, no correlation with the age of onset for disease was observed. Our results show conclusively that psoriasis vulgaris and guttate psoriasis have a similar genetic basis for their association to PSORS1, whereas palmoplantar pustulosis appears to be a distinct disorder.

This thesis presents results of an experiment to investigate the dynamics of air motions within the outflow of tropical deep convection in the upper troposphere above Darwin, Australia. The research involved analyzing in situ measurements within the anvil outflow from the Egrett aircraft and also coincident laser remote sensing measurements of cloud structure from a King Air aircraft, flying directly below the Egrett. The data included the only in situ turbulence measurements that have been obtained with a resolution of 4 meters inside of an anvil outflow. The research shows that gravity waves and coherent structures exist in the anvil outflow. High frequency gravity waves were identified from the 90ᵒ phase lag between temperature and vertical wind oscillations. The gravity waves had wavelengths of 2 – 5 km and were observed as isolated waves with less than two oscillations, or, as extended waves with several oscillations. In some instances, correlations between temperature and vertical wind oscillations had zero phase lag between them and this was consistent with Rayleigh-Bénard convective rolls. Turbulence in the outflow was observed to be intense within patches separated by more quiescent flow. This turbulence had some characteristics that were unique in comparison to previous turbulence measurements at similar altitudes in the jet stream or midlatitude cirrus clouds. The ratio of the power spectral density of vertical wind fluctuations to the horizontal wind fluctuations was greater in the anvil outflow in comparison to the measurements in turbulence generated by shear in mid latitude jet stream and cirrus clouds. The relative magnitude of the vertical wind fluctuation spectrum decreases at all wavelengths with increasing distance away from the core region of the storm. This constitutes the first evidence that is consistent with theoretical predictions of “stratified turbulence.” Measurements in flights above and below the outflow base indicate that momentum flu

Le récit du réfugié peut être étudié à la lumière du récit de l’analysant, avec lequel il partage un certain nombre de similitudes. Ces deux récits de souffrance demandent, sont écoutés, interrogés, interprétés. Cherchant à dire une histoire personnelle dans l’Histoire, entre mémoire et résistance, réalité et fantasme, ces récits ouvrent un lieu de liberté, et l’espace d’une re-création de soi avec l’autre., Are Stories Told by Refugees Fictions ? The stories told by refugees may be studied in the same light as that used to examine those told by analysands as the two are similar in many ways. Both are accounts of suffering addressed to others, both are listened to, questioned and interpreted. They are a means of expressing one’s personal history as a part of History, somewhere between memory and resistance, reality and fantasy and such stories create a place of total freedom, in which the bonds between self and other may be rebuilt.

Cet article détaille la pluralité du système éducatif destiné aux populations réfugiées dans la capitale indienne, Delhi. Il expose le rôle des différents acteurs qui interviennent dans le champ de l’éducation : les organisations de tutelle des réfugiés mais également, comblant une part du vide laissé par ces institutions, des fondations politiques et des Églises qui participent à l’établissement d’un dispositif pluriel et hybride, au cœur duquel les réfugiés évoluent. Cette étude permet de montrer l’articulation existant entre les différents acteurs qui interviennent auprès des réfugiés mais aussi la part de ces derniers dans la définition des cadres éducatifs., The multiplicity of the refugee educational offer in Delhi India This paper examines the plurality of the education system intended for the refugee populations in the Indian capital, Delhi. It describes the role of the different actors involved in the educational field : the Tibetan administration and the UNHCR but also, filling part of the gap, political foundations and Churches, which participate in creating a plural and hybrid device, in the middle of which refugees evolve. This case study shows the links that exist between these different actors and the role of the refugees themselves in defining educational frameworks.

RésuméL’objectif de cette contribution est d’interroger la politique d’asile mise en œuvre par le HCR à la lumière des différentes options préconisées par l’institution à Delhi. La réflexion est organisée autour de deux axes. Le premier est consacré à l’analyse des solutions mises en œuvre localement par le HCR, qui adapte ses solutions de principe à la réalité indienne et internationale. Dans le deuxième axe, l’analyse, selon une approche diachronique de la politique de l’agence à Delhi depuis les années 1980, apporte l’illustration des mutations à l’œuvre dans le mandat de l’agence des Nations Unies et montre les répercussions qu’elles ont sur le statut de réfugié., This article aims at nurturing a reflection on UNHCR’s asylum policy by looking at the different solutions proposed by the institution in Delhi. The paper is organised around two points. The first one is devoted to the analysis of the solutions UNHCR locally implements, adapting his principle solutions to the Indian and international reality. In the second point an historical approach of UNHCR’s policy since the 1980s gives the illustration of the changes at work in the mandate of the United Nations’ agency and shows the consequences of these changes on the refugee status.