1. Hidradenitis suppurativa is associated with non-alcoholic fatty liver disease:A cross-sectional study
- Author
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González-Villanueva, Iris, DE GRACIA, Cristina, Planells, Mariana, Poveda, Inés, Álvarez, Pedro, Schneller-Pavelescu, Luca, Betlloch, Isabel, Jemec, Gregor B., Ramos, José M., Pascual, José C., González-Villanueva, Iris, DE GRACIA, Cristina, Planells, Mariana, Poveda, Inés, Álvarez, Pedro, Schneller-Pavelescu, Luca, Betlloch, Isabel, Jemec, Gregor B., Ramos, José M., and Pascual, José C.
- Abstract
Non-alcoholic fatty liver disease (NAFLD) is currently the most common cause of end-stage liver disease. The aim of this controlled cross-sectional study was to as-sess the association between NAFLD and hidradenitis suppurativa. NAFLD was assessed using hepatic ultra-sound. A total of 125 patients with hidradenitis suppu-rativa and 120 patients without hidradenitis suppu-rativa were recruited, matched for age, sex and body mass index (< 25 or ≥ 25 kg/m2), a risk factor related to NAFLD. Both groups presented similar proportions of overweight or obesity (89.6% vs 90%). Patients with hidradenitis suppurativa presented significantly higher prevalence of NAFLD compared with those with non-hidradenitis suppurativa (57.6% vs 31.7%, p < 0.001). Multivariable analysis confirmed independent association between hidradenitis suppurativa and NAFLD (odds ratio 2.79, 95% confidence interval 1.48–5.25; p = 0.001) besides age, body mass index, hypertension and hypertransaminasaemia. Hidrade-nitis suppurativa is significantly associated with the development of NALFD regardless of the presence of classic metabolic risk factors.
- Published
- 2020