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1. Effectiveness of psychological support to healthcare workers by the occupational health service: a pilot experience

Author

Dalmasso, Guendalina, Di Prinzio, Reparata Rosa, Gilardi, F., De Falco, F., Vinci, Maria Rosaria, Camisa, Vincenzo, Santoro, A., Casasanta, D., Raponi, M., Giorgi, G., Magnavita, Nicola, Zaffina, Salvatore, Dalmasso G., Di Prinzio R. R., Vinci M. R., Camisa V., Magnavita N. (ORCID:0000-0002-0988-7344), Zaffina S. (ORCID:0000-0002-8858-5423), Dalmasso, Guendalina, Di Prinzio, Reparata Rosa, Gilardi, F., De Falco, F., Vinci, Maria Rosaria, Camisa, Vincenzo, Santoro, A., Casasanta, D., Raponi, M., Giorgi, G., Magnavita, Nicola, Zaffina, Salvatore, Dalmasso G., Di Prinzio R. R., Vinci M. R., Camisa V., Magnavita N. (ORCID:0000-0002-0988-7344), and Zaffina S. (ORCID:0000-0002-8858-5423)

Abstract

Work-related stress is a significant risk for healthcare workers (HCWs). This study aims aevaluating the effectiveness of an individual psychological support programme for hospital workersIn all, 35 workers participated (n). A control group of 245 workers (7n) was set. Occupationadistress was measured by the General Health Questionnaire, (GHQ-12), the quality of life by the Short Form-36 health survey, (SF-36), and sickness absence was recorded. Costs and benefits of the service were evaluated and the return on investment (ROI) was calculated. The level of distress was significantly reduced in the treated group at the end of the follow-up (p < 0.001). Quality of life had significantly improved (p < 0.003). A 60% reduction of sickness absence days (SADs) following the intervention was recorded. After the treatment, absenteeism in cases was significantly lower than in controls (p < 0.02). The individual improvement of mental health and quality of life was significantly correlated with the number of meetings with the psychologist (p < 0.01 and p < 0.03, respectively)The recovery of direct costs due to reduced sick leave absence was significantly higher than the costs of the programme; ROI was 2.73. The results must be examined with caution, given the very limited number of workers treated; this first study, however, encouraged us to continue the experience.

Published
2021

2. Recurrence, Reactivation, or Inflammatory Rebound of SARS-CoV-2 Infection With Acute Vestibular Symptoms: A Case Report and Revision of Literature

Author

Zaffina, Salvatore, Lanteri, P., Gilardi, F., Garbarino, Sergio, Santoro, A., Vinci, Maria Rosaria, Carsetti, Rita, Scorpecci, A., Raponi, M., Magnavita, Nicola, Camisa, Vincenzo, Zaffina S. (ORCID:0000-0002-8858-5423), Garbarino S., Vinci M. R., Carsetti R., Magnavita N. (ORCID:0000-0002-0988-7344), Camisa V., Zaffina, Salvatore, Lanteri, P., Gilardi, F., Garbarino, Sergio, Santoro, A., Vinci, Maria Rosaria, Carsetti, Rita, Scorpecci, A., Raponi, M., Magnavita, Nicola, Camisa, Vincenzo, Zaffina S. (ORCID:0000-0002-8858-5423), Garbarino S., Vinci M. R., Carsetti R., Magnavita N. (ORCID:0000-0002-0988-7344), and Camisa V.

Abstract

A case of recurrent coronavirus disease 2019 (COVID-19) with neurovestibular symptoms was reported. In March 2020, a physician working in an Italian pediatric hospital had flu-like symptoms with anosmia and dysgeusia, and following a reverse transcription PCR (RT/PCR) test with a nasopharyngeal swab tested positive for SARS-CoV-2. After home quarantine, 21 days from the beginning of the symptoms, the patient tested negative in two subsequent swabs and was declared healed and readmitted to work. Serological testing showed a low level of immunoglobulin G (IgG) antibody title and absence of immunoglobulin M (IgM). However, 2 weeks later, before resuming work, the patient complained of acute vestibular syndrome, and the RT/PCR test with mucosal swab turned positive. On the basis of the literature examined and reviewed for recurrence cases and vestibular symptoms during COVID-19, to our knowledge this case is the first case of recurrence with vestibular impairment as a neurological symptom, and we defined it as probably a viral reactivation. The PCR retest positivity cannot differentiate re-infectivity, relapse, and dead-viral RNA detection. Serological antibody testing and viral genome sequencing could be always performed in recurrence cases.

Published
2021

3. Return on investment (ROI) and development of a workplace disability management program in a hospital—a pilot evaluation study

Author

Camisa, Vincenzo, Gilardi, F., Di Brino, E., Santoro, A., Vinci, Maria Rosaria, Sannino, S., Bianchi, N., Mesolella, V., Macina, N., Focarelli, M., Brugaletta, R., Raponi, M., Ferri, L., Cicchetti, Americo, Magnavita, Nicola, Zaffina, Salvatore, Camisa V., Vinci M. R., Cicchetti A. (ORCID:0000-0002-4633-9195), Magnavita N. (ORCID:0000-0002-0988-7344), Zaffina S. (ORCID:0000-0002-8858-5423), Camisa, Vincenzo, Gilardi, F., Di Brino, E., Santoro, A., Vinci, Maria Rosaria, Sannino, S., Bianchi, N., Mesolella, V., Macina, N., Focarelli, M., Brugaletta, R., Raponi, M., Ferri, L., Cicchetti, Americo, Magnavita, Nicola, Zaffina, Salvatore, Camisa V., Vinci M. R., Cicchetti A. (ORCID:0000-0002-4633-9195), Magnavita N. (ORCID:0000-0002-0988-7344), and Zaffina S. (ORCID:0000-0002-8858-5423)

Abstract

The progressive ageing of the working population and the increase in related chronic diseases tend to affect working capacity. The aim of this study was to evaluate a Workplace Disability Management Program (WDMP) within a pediatric hospital. Absenteeism due to healthcare workers’ (HCWs) pre-and post-WDMP and the related costs were used for the program evaluation. The Return on Investment (ROI), the Break-Even Analysis (BEA) and the value of the average annual productivity of HCWs who took advantage of the Disability Management (DM) interventions to assess the economic impact of the program, were also used. The HCWs enrolled in the program were 131 (approximately 4% of hospital staff), of which 89.7% females and with an average age of 50.4 years (SD ± 8.99). Sick leave days of the HCWs involved decreased by 66.6% in the year following the end of WDMP compared to the previous one (p < 0.001). The total estimated cost reduction of absenteeism is 427,896 € over a year. ROI was equal to 27.66 €. BEA indicated that the break-even point was reached by implementing the program on 3.27 HCWs. The program evaluation demonstrated the particular effectiveness of the implemented WDMP model, acting positively on the variables that affect productivity and the limitation to work.

Published
2020

4. Robotic Technology in Pediatric Neurorehabilitation. A Pilot Study of Human Factors in an Italian Pediatric Hospital

Author

Gilardi, F., De Falco, F., Casasanta, D., Andellini, M., Gazzellini, S., Petrarca, M., Morocutti, Augusto, Lettori, Donatella, Ritrovato, M., Castelli, E., Raponi, M., Magnavita, Nicola, Zaffina, Salvatore, Morocutti A., Lettori D., Magnavita N. (ORCID:0000-0002-0988-7344), Zaffina S. (ORCID:0000-0002-8858-5423), Gilardi, F., De Falco, F., Casasanta, D., Andellini, M., Gazzellini, S., Petrarca, M., Morocutti, Augusto, Lettori, Donatella, Ritrovato, M., Castelli, E., Raponi, M., Magnavita, Nicola, Zaffina, Salvatore, Morocutti A., Lettori D., Magnavita N. (ORCID:0000-0002-0988-7344), and Zaffina S. (ORCID:0000-0002-8858-5423)

Abstract

The introduction of robotic neurorehabilitation among the most recent technologies in pediatrics represents a new opportunity to treat pediatric patients. This study aims at evaluating the response of physiotherapists, patients and their parents to this new technology. The study considered the outcomes of technological innovation in physiotherapists (perception of the workload, satisfaction), as well as that in patients and their parents (quality of life, expectations, satisfaction) by comparing the answers to subjective questionnaires of those who made use of the new technology with those who used the traditional therapy. A total of 12 workers, 46 patients and 47 parents were enrolled in the study. Significant differences were recorded in the total workload score of physiotherapists who use the robotic technology compared with the traditional therapy (p < 0.001). Patients reported a higher quality of life and satisfaction after the use of the robotic neurorehabilitation therapy. The parents of patients undergoing the robotic therapy have moderately higher expectations and satisfaction than those undergoing the traditional therapy. In this pilot study, the robotic neurorehabilitation technique involved a significant increase in the patients' and parents' expectations. As it frequently happens in the introduction of new technologies, physiotherapists perceived a greater workload. Further studies are needed to verify the results achieved.

Published
2020

6. Profession and context: training teachers in a systemic, co-operative and auto/biographic view

Author

Antunes, F, Ambrósio, S, Araújo e Sá, MH, Aust, K, Bancheva, E, Barros, R, Biasin, C, Brunner, S, Brusch, M, Buddeberg, K, Busher, H, Büsch, V, Castiglioni, M, Cooper, T, Cox, A, Desmarais, D, Dietel, S, Durant, C, Ebner von Eschenbach, M, Eneau, J, Enoch, C, Evans, R, Eveleigh, A., Ewing, B, Fairfoot, G, Formenti, L, Foroughi, B, Galimberti, A, Gilardi, F, Gold, M, Guimarães, P, Härnsten, G, Heikkinen, A, Holmstrand, L, Iacovides, I, Isopahkala-Bouret, U, Ivanova, M, James, N, Jennett, C, Käpplinger, B, Kloetzer, L, Kretschmer, S, Langemeyer, I, Lucio-Villegas, E, Lundgren, H, Mallard, S, Matthews, C, Morrice, L, Németh, B, Olesen, H, Palmer, A-M, Paulos, C, Pätzold, H, Piela, A, Piirainen, A, Pojarliev, A, Quintana-Murci, E, Reid, J, Riekmann, W, Riva, MG, Rohrdantz Herrmann, I, Salvà-Mut, F, Sarra, G, Lichte, N, Haberzeth, E, Kulmus, C, FORMENTI, LAURA, Antunes, F, Ambrósio, S, Araújo e Sá, MH, Aust, K, Bancheva, E, Barros, R, Biasin, C, Brunner, S, Brusch, M, Buddeberg, K, Busher, H, Büsch, V, Castiglioni, M, Cooper, T, Cox, A, Desmarais, D, Dietel, S, Durant, C, Ebner von Eschenbach, M, Eneau, J, Enoch, C, Evans, R, Eveleigh, A., Ewing, B, Fairfoot, G, Formenti, L, Foroughi, B, Galimberti, A, Gilardi, F, Gold, M, Guimarães, P, Härnsten, G, Heikkinen, A, Holmstrand, L, Iacovides, I, Isopahkala-Bouret, U, Ivanova, M, James, N, Jennett, C, Käpplinger, B, Kloetzer, L, Kretschmer, S, Langemeyer, I, Lucio-Villegas, E, Lundgren, H, Mallard, S, Matthews, C, Morrice, L, Németh, B, Olesen, H, Palmer, A-M, Paulos, C, Pätzold, H, Piela, A, Piirainen, A, Pojarliev, A, Quintana-Murci, E, Reid, J, Riekmann, W, Riva, MG, Rohrdantz Herrmann, I, Salvà-Mut, F, Sarra, G, Lichte, N, Haberzeth, E, Kulmus, C, and FORMENTI, LAURA

Abstract

In the framework of lifelong and lifewide learning, training for teachers should be aimed to foster their positive attitude towards learning and learning to learn. A systemic, constructivist and auto/biographical approach was used in a course for teachers in mathematics and physics. To propitiate lifelong and lifewide learning, they were invited to taka an active and reflexive position towards their experience at school, teacher/student relationships, and concept of learning. The general aim was to develop a reflexive attitude and explicit ideas about knowledge, learning and the subject matter. Auto/biographical participatory inquiry was used as a method to learn through research, where learners were invited to develop an individual and collective satisfying theory about their choice to become a teacher, their struggles for identity, and the challenges of a difficult social and professional situation.

Published
2014

7. Influenza vaccination coverage among medical residents: an Italian multicenter survey

Author

Costantino, C, Mazzucco, Walter, Azzolini, E, Baldini, C, Bergomi, M, Biafiore, Ad, Bianco, M, Borsari, L, Cacciari, P, Cadeddu, Chiara, Camia, P, Carluccio, E, Conti, A, De Waure, Chiara, Di Gregori, V, Fabiani, L, Fallico, R, Filisetti, B, Flacco, Me, Franco, E, Furnari, R, Galis, V, Gallea, Mr, Gallone, Mf, Gallone, S, Gelatti, U, Gilardi, F, Giuliani, Ar, Grillo, Oc, Lanati, N, Mascaretti, S, Mattei, A, Micò, R, Morciano, L, Nante, N, Napoli, G, Nobile, Cg, Palladino, R, Parisi, S, Passaro, M, Pelissero, G, Quarto, M, Ricciardi, Walter, Romano, G, Rustico, E, Saponari, A, Schioppa, F, Signorelli, C, Siliquini, R, Trabacchi, V, Triassi, M, Varetta, A, Ziglio, A, Zoccali, A, Vitale, F, Amodio, E., Cadeddu, Chiara (ORCID:0000-0003-0149-1078), De Waure, Chiara (ORCID:0000-0002-4346-1494), Ricciardi, Gualtiero (ORCID:0000-0002-5655-688X), Costantino, C, Mazzucco, Walter, Azzolini, E, Baldini, C, Bergomi, M, Biafiore, Ad, Bianco, M, Borsari, L, Cacciari, P, Cadeddu, Chiara, Camia, P, Carluccio, E, Conti, A, De Waure, Chiara, Di Gregori, V, Fabiani, L, Fallico, R, Filisetti, B, Flacco, Me, Franco, E, Furnari, R, Galis, V, Gallea, Mr, Gallone, Mf, Gallone, S, Gelatti, U, Gilardi, F, Giuliani, Ar, Grillo, Oc, Lanati, N, Mascaretti, S, Mattei, A, Micò, R, Morciano, L, Nante, N, Napoli, G, Nobile, Cg, Palladino, R, Parisi, S, Passaro, M, Pelissero, G, Quarto, M, Ricciardi, Walter, Romano, G, Rustico, E, Saponari, A, Schioppa, F, Signorelli, C, Siliquini, R, Trabacchi, V, Triassi, M, Varetta, A, Ziglio, A, Zoccali, A, Vitale, F, Amodio, E., Cadeddu, Chiara (ORCID:0000-0003-0149-1078), De Waure, Chiara (ORCID:0000-0002-4346-1494), and Ricciardi, Gualtiero (ORCID:0000-0002-5655-688X)

Abstract

Although influenza vaccination is recognized to be safe and effective, recent studies have confirmed that immunization coverage among health care workers remain generally low, especially among medical residents (MRs). Aim of the present multicenter study was to investigate attitudes and determinants associated with acceptance of influenza vaccination among Italian MRs. A survey was performed in 2012 on MRs attending post-graduate schools of 18 Italian Universities. Each participant was interviewed via an anonymous, self-administered, web-based questionnaire including questions on attitudes regarding influenza vaccination. A total of 2506 MRs were recruited in the survey and 299 (11.9%) of these stated they had accepted influenza vaccination in 2011-2012 season. Vaccinated MRs were older (P = 0.006), working in clinical settings (P = 0.048), and vaccinated in the 2 previous seasons (P<0.001 in both seasons). Moreover, MRs who had recommended influenza vaccination to their patients were significantly more compliant with influenza vaccination uptake in 2011-2012 season (P<0.001). "To avoid spreading influenza among patients" was recognized as the main reason for accepting vaccination by less than 15% of vaccinated MRs. Italian MRs seem to have a very low compliance with influenza vaccination and they seem to accept influenza vaccination as a habit that is unrelated to professional and ethical responsibility. Otherwise, residents who refuse vaccination in the previous seasons usually maintain their behaviors. Promoting correct attitudes and good practice in order to improve the influenza immunization rates of MRs could represent a decisive goal for increasing immunization coverage among health care workers of the future.

Published
2014

8. Quantifying ChIP-seq data: a spiking method providing an internal reference for sample-to-sample normalization

Author

Bonhoure, N, Bounova, G, Bernasconi, D, Praz, V, Lammers, F, Canella, D, Willis, I M, Herr, W, Hernandez, N, Delorenzi, M, Deplancke, B, Desvergne, B, Guex, N, Naef, F, Rougemont, J, Schibler, U, Andersin, T, Cousin, P, Gilardi, F, Gos, P, Raghav, S, Villeneuve, D, Fabbretti, R, Vlegel, V, Xenarios, I, Migliavacca, E, David, F, Jarosz, Y, Kuznetsov, D, Liechti, R, Martin, O, Delafontaine, J, Cajan, J, Gustafson, K, Krier, I, Leleu, M, Molina, N, Naldi, A, Rib, L, Symul, L, Bonhoure, N, Bounova, G, Bernasconi, D, Praz, V, Lammers, F, Canella, D, Willis, I M, Herr, W, Hernandez, N, Delorenzi, M, Deplancke, B, Desvergne, B, Guex, N, Naef, F, Rougemont, J, Schibler, U, Andersin, T, Cousin, P, Gilardi, F, Gos, P, Raghav, S, Villeneuve, D, Fabbretti, R, Vlegel, V, Xenarios, I, Migliavacca, E, David, F, Jarosz, Y, Kuznetsov, D, Liechti, R, Martin, O, Delafontaine, J, Cajan, J, Gustafson, K, Krier, I, Leleu, M, Molina, N, Naldi, A, Rib, L, and Symul, L

Published
2014

9. Italian cancer figures, report 2012: Cancer in children and adolescents

Author

Pisani, P, Buzzoni, C, Crocetti, E, Maso, L, Rondelli, R, Alessi, D, Aricò, M, Bidoli, E, Ferrari, A, Fusco, M, Gatta, G, Guzzinati, S, Jankovic, M, Locatelli, F, Maule, M, Mosso, M, Pastore, G, Pession, A, Rashid, I, Sacerdote, C, Terracini, B, Tognazzo, S, Trama, A, Ferretti, S, Porta, F, Mazzoleni, G, Tschugguel, B, De Valiere, E, Facchinelli, G, Falk, M, Cappello, T, Giacomin, A, Vercellino, P, Andreone, S, Marzola, L, Migliari, E, Carletti, N, Nenci, I, Caldarella, A, Corbinelli, A, Intrieri, T, Manneschi, G, Nemcova, L, Ocello, C, Sacchettini, C, Zappa, M, Paci, E, Serraino, D, Angelin, T, Birri, S, De Dottori, M, De Santis, E, Forgiarini, O, Zucchetto, A, Zanier, L, Vercelli, M, Orengo, M, Casella, C, Marani, E, Puppo, A, Celesia, M, Cogno, R, Levrieri, I, Manenti, S, Garrone, E, Quaglia, A, Pannozzo, F, Busco, S, Ramazzotti, V, Cercato, M, Battisti, W, Sperduti, I, Macci, L, Bugliarello, E, Valerio, O, Bernazza, E, Tamburo, L, Rossi, M, Curatella, S, Tamburrino, S, Fattoruso, S, Bisanti, L, Autelitano, M, Cuccaro, F, Randi, G, Ghilardi, S, Leone, R, Filipazzi, L, Bonini, A, Giubelli, C, Federico, M, Artioli, M, Valla, K, Braghiroli, B, Cirilli, C, Luminari, S, Pirani, M, Ferrari, L, Bellatalla, C, Panico, M, Perrotta, C, Vassante, B, Vitale, M, Michiara, M, Bozzani, F, Sgargi, P, Tumino, R, Rosa, M, Cascone, G, Frasca, G, Giurdanella, M, Martorana, C, Morana, G, Nicita, C, Rollo, P, Ruggeri, M, Sigona, A, Spata, E, Vacirca, S, Mangone, L, Di Felice, E, Pezzarossi, A, Caroli, S, Pellegri, C, Vicentini, M, D'Angelo, S, Balottari, P, Romagna, R, Falcini, F, Colamartini, A, Bucchi, L, Balducci, C, Ravegnani, M, Vitali, B, Cordaro, C, Caprara, L, Giuliani, O, Giorgetti, S, Palumbo, M, Vattiato, R, Ravaioli, A, Mancini, S, Tonelli, C, Amadori, M, Cremone, L, Iannelli, A, Senatore, G, Zevola, A, Sechi, O, Budroni, M, Cesaraccio, R, Pirino, D, Carboni, D, Fiori, G, Soddu, M, Mameli, G, Mura, F, Contrino, M, Madeddu, A, Tisano, F, Sciacca, S, Muni, A, Mizzi, M, Russo, M, Sacco, G, Aletta, P, Ziino, A, Tessandori, R, Fanetti, A, Maspero, S, Cecconami, L, Annulli, M, Moroni, E, Gonzalez, M, Zanetti, R, Rosso, S, Patriarca, S, Prandi, R, Sobrato, I, Gilardi, F, Busso, P, Piffer, S, Rizzello, R, Gentilini, M, Cappelletti, M, Rosa, F, Stracci, F, D'Alò, D, Scheibel, M, Costarelli, D, Spano, F, Rossini, S, Santucci, C, Petrinelli, A, Solimene, C, Bianconi, F, Brunori, V, Crosignani, P, Tagliabue, G, Contiero, P, Preto, L, Tittarelli, A, Maghini, A, Codazzi, T, Frassoldi, E, Gada, D, Costa, E, Grazia, L, Zambon, P, Baracco, M, Bovo, E, Cin, A, Fiore, A, Greco, A, Monetti, D, Rosano, A, Stocco, C, Donato, F, Limina, R, Adorni, A, Andreis, P, Zani, G, Piovani, F, Salvi, O, Puleio, M, Vitarelli, S, Candela, G, Pappalardo, G, Scuderi, T, Lottero, B, Ribaudo, M, Ricci, P, Guarda, L, Gatti, L, Bozzeda, A, Dall'Acqua, M, Pironi, V, Sardo, A, Mazzei, A, Sirianni, N, Lavecchia, A, Mancuso, P, Vitale, F, Cusimano, R, Amodio, R, Guttadauro, A, Ravazzolo, B, Bucalo, G, Trapani, C, Sunseri, R, Cascio, M, Brucculeri, M, Adamo, M, Mannino, R, Mistretta, A, Costa, A, Rudisi, G, Gola, G, Corti, M, Prosperini, E, Grandi, L, Sciacchitano, S, Fidelbo, M, Benedetto, G, Vasquez, E, Torrisi, A, Pesce, P, Calabretta, L, Bella, F, Leone, A, Ieni, A, Varvarà, M, Castaing, M, Di Prima, A, Benedetto, A, Paderni, F, Usala, M, Pala, F, Sini, G, Pintori, N, Canu, L, Demurtas, G, Doa, N, Lazzarato, F, Magnani, C, Merletti, F, Sarcerdote, C, Macerata, V, de Leon, M, Domati, F, Rossi, G, Goldoni, C, Rossi, F, De Gaetani, C, Benatti, P, Roncucci, L, Di Gregorio, C, Pedroni, M, Pezzi, A, Maffei, S, Mariani, F, Borsi, E, Cocchioni, M, Pascucci, C, Gennaro, V, Lazzarotto, A, Benfatto, L, Mazzucco, G, Montanaro, F, Traina, A, Carruba, G, Dolcemascolo, C, Staiti, R, Zarcone, M, Bisogno, G, Cuttini, M, De Rosa, M, Haupt, R, Soresina, A, Valsecchi, M, Fagioli, F, Bona, G, Dini, G, Conter, V, Biondi, A, Zecca, M, Fedeli, F, Massimino, M, Nespoli, L, Roncarolo, M, Basso, G, Cesaro, S, Memo, L, Bellettato, M, Tamaro, P, Mascarin, M, Rosolen, A, Izzi, G, Paolucci, P, Borgna Pignatti, C, Vecchi, V, Abate, M, D'Ambrosio, A, Favre, C, Caniglia, M, Pierani, P, Felici, L, Visani, G, Fioritoni, G, Foà, R, Riccardi, R, Frega, G, Clerico, A, Casale, F, Poggi, V, Amendola, G, Filosa, A, Ladogana, S, Presta, G, Tornesello, A, De Mattia, D, Consarino, C, Nobile, F, Sperlì, D, D'Angelo, P, Marino, S, Cosmi, C, Mura, R, Battisti, L, Maso, LD, Mosso, ML, Cappello, TD, Vercellino, PC, Orengo, MA, Celesia, MV, Cercato, MC, Artioli, ME, Vitale, MF, Rosa, MG, Giurdanella, MC, Rollo, PC, Ruggeri, MG, Romagna, Rt, Contrino, ML, Ziino, AC, Fanetti, AC, Annulli, ML, Gonzalez, ME, Gentilini, MA, Rosa, FL, Petrinelli, AM, Grazia, Ld, Cin, AD, Fiore, AR, Limina, RM, Sardo, AS, Lavecchia, AM, Cascio, MA, Brucculeri, MA, Adamo, MS, Sini, GM, de Leon, MP, Goldoni, CA, VALSECCHI, MARIA GRAZIA, BIONDI, ANDREA, Roncarolo, MG, Abate, ME, Mura, RM, Battisti, L., Pisani, P, Buzzoni, C, Crocetti, E, Maso, L, Rondelli, R, Alessi, D, Aricò, M, Bidoli, E, Ferrari, A, Fusco, M, Gatta, G, Guzzinati, S, Jankovic, M, Locatelli, F, Maule, M, Mosso, M, Pastore, G, Pession, A, Rashid, I, Sacerdote, C, Terracini, B, Tognazzo, S, Trama, A, Ferretti, S, Porta, F, Mazzoleni, G, Tschugguel, B, De Valiere, E, Facchinelli, G, Falk, M, Cappello, T, Giacomin, A, Vercellino, P, Andreone, S, Marzola, L, Migliari, E, Carletti, N, Nenci, I, Caldarella, A, Corbinelli, A, Intrieri, T, Manneschi, G, Nemcova, L, Ocello, C, Sacchettini, C, Zappa, M, Paci, E, Serraino, D, Angelin, T, Birri, S, De Dottori, M, De Santis, E, Forgiarini, O, Zucchetto, A, Zanier, L, Vercelli, M, Orengo, M, Casella, C, Marani, E, Puppo, A, Celesia, M, Cogno, R, Levrieri, I, Manenti, S, Garrone, E, Quaglia, A, Pannozzo, F, Busco, S, Ramazzotti, V, Cercato, M, Battisti, W, Sperduti, I, Macci, L, Bugliarello, E, Valerio, O, Bernazza, E, Tamburo, L, Rossi, M, Curatella, S, Tamburrino, S, Fattoruso, S, Bisanti, L, 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Abstract

This study describes up-to-date cancer incidence and survival in Italian paediatric and adolescent patients, based on data collected by the network of Italian cancer registries (AIRTUM). It updates the monograph published on the same topic in 2008. The main objective of this monograph is to present the statistics according to standard rigorous epidemiological methods and disseminate them to a wide range of readers, including the lay public. Given the deep impact of the 2008 monograph on the general public, in this update we complement descriptive statistics with additional data and commentaries on issues of importance for public health, in order to provide unambiguous criteria on how to interpret the statistics. The study is the result of the collaboration between AIRTUM and AIEOP (Italian Association of Paediatric Haematology and Oncology) with contributions from interested parties, including representatives of parent associations. The monograph is divided into three parts. The first part presents incidence rates, survival probabilities, and time trends, by sex, age, geographical area, and cancer site or type, by means of tables and graphs as in the previous monograph, to facilitate direct comparisons. Four articles summarize and comment the results. The second part uses data from AIRTUM and AIEOP to outline patient management and health care issues; it includes estimates of the number of new cases in the next decade and of young adults living after a paediatric cancer diagnosis. Health organizational aspects of treatment services for paediatric patients, based on the AIEOP database, are also discussed, along with long-term complications in cured patients. The third section describes the changes in mortality trends due to improving therapies and healthcare services, and discusses risk factors and prevention of childhood cancer, late adverse events in cured patients, and other related issues.

Published
2013

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