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Purpose To investigate associations between substitutions of foods varying in fat quality and all-cause mortality in elderly Swedish men and to examine effect measure modification by a gene involved in fatty acid desaturation (rs174550 FADS1). Methods Using Cox-regression models in the ULSAM cohort (n = 1133 men aged 71), we aimed to investigate; (1) Associations between the substitution of a nutrient or food for another on all-cause mortality (primary outcome) and CVD (secondary outcome) and (2) Associations between the addition of various fat-rich foods to the habitual diet and all-cause mortality and CVD. Subgroup analyses based on the rs174550 FADS1 genotype were conducted. Results Over a mean follow-up of 11.6–13.7 years, n = 774 died and n = 494 developed CVD, respectively. No clear associations were observed for the vast majority of substitution nor addition models. Adding saturated fatty acids (SFA) on top of the habitual diet was however associated with an increased risk of mortality in men with the CT/CC-genotype [HR (95% CI) 1.44 (1.05, 1.97)]. Post-hoc analyses showed an inverse association of substituting SFA with carbohydrates [HR (95% CI) 0.79 (0.65, 0.97)], which was somewhat stronger in men with the CT/CC-genotype compared to men carrying the TT-genotype. Conclusions Few associations were observed between diet and all-cause mortality and CVD in this population. However, substituting SFA with carbohydrates was associated with lower mortality in post-hoc analyses and adding SFA to the habitual diet increased mortality in men with the CT/CC-genotype. The latter observation is novel and warrants further investigation in larger cohort studies including women.

Purpose To investigate associations between substitutions of foods varying in fat quality and all-cause mortality in elderly Swedish men and to examine effect measure modification by a gene involved in fatty acid desaturation (rs174550 FADS1). Methods Using Cox-regression models in the ULSAM cohort (n = 1133 men aged 71), we aimed to investigate; (1) Associations between the substitution of a nutrient or food for another on all-cause mortality (primary outcome) and CVD (secondary outcome) and (2) Associations between the addition of various fat-rich foods to the habitual diet and all-cause mortality and CVD. Subgroup analyses based on the rs174550 FADS1 genotype were conducted. Results Over a mean follow-up of 11.6–13.7 years, n = 774 died and n = 494 developed CVD, respectively. No clear associations were observed for the vast majority of substitution nor addition models. Adding saturated fatty acids (SFA) on top of the habitual diet was however associated with an increased risk of mortality in men with the CT/CC-genotype [HR (95% CI) 1.44 (1.05, 1.97)]. Post-hoc analyses showed an inverse association of substituting SFA with carbohydrates [HR (95% CI) 0.79 (0.65, 0.97)], which was somewhat stronger in men with the CT/CC-genotype compared to men carrying the TT-genotype. Conclusions Few associations were observed between diet and all-cause mortality and CVD in this population. However, substituting SFA with carbohydrates was associated with lower mortality in post-hoc analyses and adding SFA to the habitual diet increased mortality in men with the CT/CC-genotype. The latter observation is novel and warrants further investigation in larger cohort studies including women.

Purpose To investigate associations between substitutions of foods varying in fat quality and all-cause mortality in elderly Swedish men and to examine effect measure modification by a gene involved in fatty acid desaturation (rs174550 FADS1). Methods Using Cox-regression models in the ULSAM cohort (n = 1133 men aged 71), we aimed to investigate; (1) Associations between the substitution of a nutrient or food for another on all-cause mortality (primary outcome) and CVD (secondary outcome) and (2) Associations between the addition of various fat-rich foods to the habitual diet and all-cause mortality and CVD. Subgroup analyses based on the rs174550 FADS1 genotype were conducted. Results Over a mean follow-up of 11.6–13.7 years, n = 774 died and n = 494 developed CVD, respectively. No clear associations were observed for the vast majority of substitution nor addition models. Adding saturated fatty acids (SFA) on top of the habitual diet was however associated with an increased risk of mortality in men with the CT/CC-genotype [HR (95% CI) 1.44 (1.05, 1.97)]. Post-hoc analyses showed an inverse association of substituting SFA with carbohydrates [HR (95% CI) 0.79 (0.65, 0.97)], which was somewhat stronger in men with the CT/CC-genotype compared to men carrying the TT-genotype. Conclusions Few associations were observed between diet and all-cause mortality and CVD in this population. However, substituting SFA with carbohydrates was associated with lower mortality in post-hoc analyses and adding SFA to the habitual diet increased mortality in men with the CT/CC-genotype. The latter observation is novel and warrants further investigation in larger cohort studies including women.

Purpose To investigate associations between substitutions of foods varying in fat quality and all-cause mortality in elderly Swedish men and to examine effect measure modification by a gene involved in fatty acid desaturation (rs174550 FADS1). Methods Using Cox-regression models in the ULSAM cohort (n = 1133 men aged 71), we aimed to investigate; (1) Associations between the substitution of a nutrient or food for another on all-cause mortality (primary outcome) and CVD (secondary outcome) and (2) Associations between the addition of various fat-rich foods to the habitual diet and all-cause mortality and CVD. Subgroup analyses based on the rs174550 FADS1 genotype were conducted. Results Over a mean follow-up of 11.6–13.7 years, n = 774 died and n = 494 developed CVD, respectively. No clear associations were observed for the vast majority of substitution nor addition models. Adding saturated fatty acids (SFA) on top of the habitual diet was however associated with an increased risk of mortality in men with the CT/CC-genotype [HR (95% CI) 1.44 (1.05, 1.97)]. Post-hoc analyses showed an inverse association of substituting SFA with carbohydrates [HR (95% CI) 0.79 (0.65, 0.97)], which was somewhat stronger in men with the CT/CC-genotype compared to men carrying the TT-genotype. Conclusions Few associations were observed between diet and all-cause mortality and CVD in this population. However, substituting SFA with carbohydrates was associated with lower mortality in post-hoc analyses and adding SFA to the habitual diet increased mortality in men with the CT/CC-genotype. The latter observation is novel and warrants further investigation in larger cohort studies including women.

Purpose To investigate associations between substitutions of foods varying in fat quality and all-cause mortality in elderly Swedish men and to examine effect measure modification by a gene involved in fatty acid desaturation (rs174550 FADS1). Methods Using Cox-regression models in the ULSAM cohort (n = 1133 men aged 71), we aimed to investigate; (1) Associations between the substitution of a nutrient or food for another on all-cause mortality (primary outcome) and CVD (secondary outcome) and (2) Associations between the addition of various fat-rich foods to the habitual diet and all-cause mortality and CVD. Subgroup analyses based on the rs174550 FADS1 genotype were conducted. Results Over a mean follow-up of 11.6–13.7 years, n = 774 died and n = 494 developed CVD, respectively. No clear associations were observed for the vast majority of substitution nor addition models. Adding saturated fatty acids (SFA) on top of the habitual diet was however associated with an increased risk of mortality in men with the CT/CC-genotype [HR (95% CI) 1.44 (1.05, 1.97)]. Post-hoc analyses showed an inverse association of substituting SFA with carbohydrates [HR (95% CI) 0.79 (0.65, 0.97)], which was somewhat stronger in men with the CT/CC-genotype compared to men carrying the TT-genotype. Conclusions Few associations were observed between diet and all-cause mortality and CVD in this population. However, substituting SFA with carbohydrates was associated with lower mortality in post-hoc analyses and adding SFA to the habitual diet increased mortality in men with the CT/CC-genotype. The latter observation is novel and warrants further investigation in larger cohort studies including women.

Targeting tunas associated with drifting Fish Aggregating Devices (dFADs) raises questions on the sustainability of tropical tuna fisheries. To limit catches of juvenile tunas, multiple time-area dFADs-fishing moratoria have been implemented by ICCAT since 1998. In this study we assessed the effectiveness of two different dFADs time-area closures implemented for the protection of both bigeye and yellowfin tuna juveniles. Using Atlantic Ocean Tunas Tagging Program (AOTTP) data from 2016 to 2019, we estimated the relative risk for individuals tagged inside the moratorium strata to be recaptured inside in comparison to the recapture rate outside the spatio-temporal strata. AOTTP releases were not homogeneously distributed in terms of areas and school type, therefore to assess the effect of the moratorium without potential bias a matching procedure was used to rebalance the release areas. As a result of the matching procedure and subsequent filtering applied to the dataset, the number of bigeyes recaptures retained inside and outside the time-area closure were below the threshold from which any conclusion could be drawn. In contrast, our results show that a majority of yellowfin and skipjack tunas tagged within the closed area stayed within the closed area during the moratorium period. Consequently, the last moratorium can be considered as effective for these two species, at least during the months of fishing ban on dFADs. Previous article in issue

Targeting tunas associated with drifting Fish Aggregating Devices (dFADs) raises questions on the sustainability of tropical tuna fisheries. To limit catches of juvenile tunas, multiple time-area dFADs-fishing moratoria have been implemented by ICCAT since 1998. In this study we assessed the effectiveness of two different dFADs time-area closures implemented for the protection of both bigeye and yellowfin tuna juveniles. Using Atlantic Ocean Tunas Tagging Program (AOTTP) data from 2016 to 2019, we estimated the relative risk for individuals tagged inside the moratorium strata to be recaptured inside in comparison to the recapture rate outside the spatio-temporal strata. AOTTP releases were not homogeneously distributed in terms of areas and school type, therefore to assess the effect of the moratorium without potential bias a matching procedure was used to rebalance the release areas. As a result of the matching procedure and subsequent filtering applied to the dataset, the number of bigeyes recaptures retained inside and outside the time-area closure were below the threshold from which any conclusion could be drawn. In contrast, our results show that a majority of yellowfin and skipjack tunas tagged within the closed area stayed within the closed area during the moratorium period. Consequently, the last moratorium can be considered as effective for these two species, at least during the months of fishing ban on dFADs. Previous article in issue

This paper presents an associative behavior-based abundance index (ABBI) providing direct estimates of the abundance of yellowfin tuna (Thunnus albacares) based on their associative behavior around floating objects (FOBs). Considering the associative dynamics of small yellowfin tuna individuals (<10 kg) at FOBs through residence and absence times at FOBs, together with acoustic data obtained from fisher’s echosounder buoys, the ABBI index is derived for yellowfin tuna in the western Indian Ocean over the period 2013-2019. This index accounts for both the FOB-associated and free-swimming components of the tuna populations, as well as for the effects of increasing numbers of FOBs on each component.

This paper presents an associative behavior-based abundance index (ABBI) providing direct estimates of the abundance of yellowfin tuna (Thunnus albacares) based on their associative behavior around floating objects (FOBs). Considering the associative dynamics of small yellowfin tuna individuals (<10 kg) at FOBs through residence and absence times at FOBs, together with acoustic data obtained from fisher’s echosounder buoys, the ABBI index is derived for yellowfin tuna in the western Indian Ocean over the period 2013-2019. This index accounts for both the FOB-associated and free-swimming components of the tuna populations, as well as for the effects of increasing numbers of FOBs on each component.

This paper presents an associative behavior-based abundance index (ABBI) providing direct estimates of the abundance of yellowfin tuna (Thunnus albacares) based on their associative behavior around floating objects (FOBs). Considering the associative dynamics of small yellowfin tuna individuals (<10 kg) at FOBs through residence and absence times at FOBs, together with acoustic data obtained from fisher’s echosounder buoys, the ABBI index is derived for yellowfin tuna in the western Indian Ocean over the period 2013-2019. This index accounts for both the FOB-associated and free-swimming components of the tuna populations, as well as for the effects of increasing numbers of FOBs on each component.

This paper presents an associative behavior-based abundance index (ABBI) providing direct estimates of the abundance of yellowfin tuna (Thunnus albacares) based on their associative behavior around floating objects (FOBs). Considering the associative dynamics of small yellowfin tuna individuals (<10 kg) at FOBs through residence and absence times at FOBs, together with acoustic data obtained from fisher’s echosounder buoys, the ABBI index is derived for yellowfin tuna in the western Indian Ocean over the period 2013-2019. This index accounts for both the FOB-associated and free-swimming components of the tuna populations, as well as for the effects of increasing numbers of FOBs on each component.

The objective of the present study was to test for associations between changes in fatty acids (FAs) and changes in plasma triglyceride (TG) levels after an n-3 FA supplementation and to test whether SNPs from the FADS gene cluster were associ-ated with plasma FA levels or with specific FA patterns. A total of 210 subjects completed a 2-wk run-in period followed by 6-wk supplementation with 5g/d of fish oil. FA profiles of plasma phospholipids (PPLs) were obtained and 19 SNPs from the FADS gene cluster were genotyped. Principal component analysis was conducted and scores were calculated. There was an increase in EPA, DPA and DHA levels in PPLs as well as a decrease in ALA and all n-6 FA levels after the supplementa-tion. Factor analysis suggested 4 post-n-3 FA supplementation patterns. Changes in AA, ALA, DGLA, as well as changes in total n-3 and omega-6 FAs in absolute quantities of FAs were all associated with a change in TG levels whereas the cor-relation remained significant only for AA and DGLA when FAs were expressed as percentage of total FAs. Several SNPs from the FADS gene cluster were associated with post-supplementation FA levels. These results suggest that FAs alone or regrouped in factors could play a role in modulating plasma TG levels after fish oil supplementation. SNPs from the FADSgene cluster interact with both FAs and/or factors to modulate TG levels.

Man-made floating objects in the surface of tropical oceans, also called drifting fish aggregating devices (DFADs), attract tens of marine species, including tunas and nontuna species. In the Indian Ocean, around 80% of the sets currently made by the EU purse-seine fleet are on DFADs. Due to the importance and value of this fishery, understanding the habitat characteristics and dynamics of pelagic species aggregated under DFADs is key to improve fishery management and fishing practices. This study implements Bayesian hierarchical spatial models to investigate tuna and non-tuna species seasonal distribution based on fisheries-independent data derived from fishers’ echo-sounder buoys, environmental information (Sea Surface Temperature, Chlorophyll, Salinity, Eddie Kinetic Energy, Oxygen concentration, Sea Surface Height, Velocity and Heading) and DFAD variables (DFAD identification, days at sea). Results highlighted group-specific spatial distributions and habitat preferences, finding higher probability of tuna presence in warmer waters, with higher sea surface height and low eddy kinetic energy values. In contrast, highest probabilities of non-tuna species were found in colder and productive waters. Days at sea were relevant for both groups, with higher probabilities at objects with higher soak time. Our results also showed speciesspecific temporal distributions, suggesting that both tuna and non-tuna species may have different habitat preferences depending on the monsoon period. The new findings provided by this study will contribute to the understanding of the ecology and behavior of target and non-target species and their sustainable management.

Whether circulating fatty acids (FAs) play a causal role in the development of cardiovascular disease (CVD) remains unclear. We conducted a Mendelian randomisation study to explore the associations between plasma phospholipid FA levels and 15 CVDs. Summary-level data from the CARDIoGRAMp1usC4D, MEGASTROKE, and Atrial Fibrillation consortia and UK Biobank were used. Sixteen single-nucleotide polymorphisms (SNPs) associated with ten plasma FAs were used as instrumental variables. SNPs in or close to the FADS1 gene were associated with most FAs. We performed a secondary analysis of the association between a functional variant (rs174547) in FADS1, which encodes Delta 5-desaturase (a key enzyme in the endogenous FA synthesis), and CVD. Genetic predisposition to higher plasma alpha-linolenic, linoleic, and oleic acid levels was associated with lower odds of large-artery stroke and venous thromboembolism, whereas higher arachidonic and stearic acid levels were associated with higher odds of these two CVDs. The associations were driven by SNPs in or close to FADS1. In the secondary analysis, the minor allele of rs174547 in FADS1 was associated with significantly lower odds of any ischemic stroke, large-artery stroke, and venous thromboembolism and showed suggestive evidence of inverse association with coronary artery disease, abdominal aortic aneurysm and aortic valve stenosis. Genetically higher plasma alpha-linolenic, linoleic, and oleic acid levels are inversely associated with large-artery stroke and venous thromboembolism, whereas arachidonic and stearic acid levels are positively associated with these CVDs. The associations were driven by FADS1, which was also associated with other CVDs.

Whether circulating fatty acids (FAs) play a causal role in the development of cardiovascular disease (CVD) remains unclear. We conducted a Mendelian randomisation study to explore the associations between plasma phospholipid FA levels and 15 CVDs. Summary-level data from the CARDIoGRAMp1usC4D, MEGASTROKE, and Atrial Fibrillation consortia and UK Biobank were used. Sixteen single-nucleotide polymorphisms (SNPs) associated with ten plasma FAs were used as instrumental variables. SNPs in or close to the FADS1 gene were associated with most FAs. We performed a secondary analysis of the association between a functional variant (rs174547) in FADS1, which encodes Delta 5-desaturase (a key enzyme in the endogenous FA synthesis), and CVD. Genetic predisposition to higher plasma alpha-linolenic, linoleic, and oleic acid levels was associated with lower odds of large-artery stroke and venous thromboembolism, whereas higher arachidonic and stearic acid levels were associated with higher odds of these two CVDs. The associations were driven by SNPs in or close to FADS1. In the secondary analysis, the minor allele of rs174547 in FADS1 was associated with significantly lower odds of any ischemic stroke, large-artery stroke, and venous thromboembolism and showed suggestive evidence of inverse association with coronary artery disease, abdominal aortic aneurysm and aortic valve stenosis. Genetically higher plasma alpha-linolenic, linoleic, and oleic acid levels are inversely associated with large-artery stroke and venous thromboembolism, whereas arachidonic and stearic acid levels are positively associated with these CVDs. The associations were driven by FADS1, which was also associated with other CVDs.

Whether circulating fatty acids (FAs) play a causal role in the development of cardiovascular disease (CVD) remains unclear. We conducted a Mendelian randomisation study to explore the associations between plasma phospholipid FA levels and 15 CVDs. Summary-level data from the CARDIoGRAMp1usC4D, MEGASTROKE, and Atrial Fibrillation consortia and UK Biobank were used. Sixteen single-nucleotide polymorphisms (SNPs) associated with ten plasma FAs were used as instrumental variables. SNPs in or close to the FADS1 gene were associated with most FAs. We performed a secondary analysis of the association between a functional variant (rs174547) in FADS1, which encodes Delta 5-desaturase (a key enzyme in the endogenous FA synthesis), and CVD. Genetic predisposition to higher plasma alpha-linolenic, linoleic, and oleic acid levels was associated with lower odds of large-artery stroke and venous thromboembolism, whereas higher arachidonic and stearic acid levels were associated with higher odds of these two CVDs. The associations were driven by SNPs in or close to FADS1. In the secondary analysis, the minor allele of rs174547 in FADS1 was associated with significantly lower odds of any ischemic stroke, large-artery stroke, and venous thromboembolism and showed suggestive evidence of inverse association with coronary artery disease, abdominal aortic aneurysm and aortic valve stenosis. Genetically higher plasma alpha-linolenic, linoleic, and oleic acid levels are inversely associated with large-artery stroke and venous thromboembolism, whereas arachidonic and stearic acid levels are positively associated with these CVDs. The associations were driven by FADS1, which was also associated with other CVDs.

Whether circulating fatty acids (FAs) play a causal role in the development of cardiovascular disease (CVD) remains unclear. We conducted a Mendelian randomisation study to explore the associations between plasma phospholipid FA levels and 15 CVDs. Summary-level data from the CARDIoGRAMp1usC4D, MEGASTROKE, and Atrial Fibrillation consortia and UK Biobank were used. Sixteen single-nucleotide polymorphisms (SNPs) associated with ten plasma FAs were used as instrumental variables. SNPs in or close to the FADS1 gene were associated with most FAs. We performed a secondary analysis of the association between a functional variant (rs174547) in FADS1, which encodes Delta 5-desaturase (a key enzyme in the endogenous FA synthesis), and CVD. Genetic predisposition to higher plasma alpha-linolenic, linoleic, and oleic acid levels was associated with lower odds of large-artery stroke and venous thromboembolism, whereas higher arachidonic and stearic acid levels were associated with higher odds of these two CVDs. The associations were driven by SNPs in or close to FADS1. In the secondary analysis, the minor allele of rs174547 in FADS1 was associated with significantly lower odds of any ischemic stroke, large-artery stroke, and venous thromboembolism and showed suggestive evidence of inverse association with coronary artery disease, abdominal aortic aneurysm and aortic valve stenosis. Genetically higher plasma alpha-linolenic, linoleic, and oleic acid levels are inversely associated with large-artery stroke and venous thromboembolism, whereas arachidonic and stearic acid levels are positively associated with these CVDs. The associations were driven by FADS1, which was also associated with other CVDs.

The EU project BIOFAD was launched in August 2017. This 28-months EU project is coordinated by a Consortium comprising three European research centers: AZTI, IRD (Institut de recherche pour le développement) and IEO (Instituto Español de Oceanografía). The International Seafood Sustainability Foundation (ISSF) is also actively collaborating by providing the biodegradable materials needed to test biodegradable dFADs (drifting FADs). Following IOTC, along with other tuna RFMOs, recommendations and resolutions to promote the use of natural or biodegradable materials for dFADs, this project is seeking to develop and implement the use of dFADs with both characteristics, non-entangling and biodegradable, in the IOTC Convention Area. However, there are no technical guidelines on the type of materials and FAD designs to be used. The main objectives of the project are: (1) to test the use of specific biodegradable materials and designs for the construction of dFADs in real fishing conditions; (2) to identify options to mitigate dFADs impacts on the ecosystem; and (3) to assess the socio-economic viability of the use of biodegradable dFADs in the purse seine tropical tuna fishery. This document shows the preliminary results regarding the effectiveness of around 716 BIOFADs deployed, in terms of tuna aggregation, drift, materials’ durability, etc. in comparison to currently deployed NEFADs (non-entangling dFADs). The project BIOFAD has counted since its inception with the support of the whole EU purse seine tuna fishery and, more recently, with the collaboration of the Korean purse seine fleet.

Whether circulating fatty acids (FAs) play a causal role in the development of cardiovascular disease (CVD) remains unclear. We conducted a Mendelian randomisation study to explore the associations between plasma phospholipid FA levels and 15 CVDs. Summary-level data from the CARDIoGRAMp1usC4D, MEGASTROKE, and Atrial Fibrillation consortia and UK Biobank were used. Sixteen single-nucleotide polymorphisms (SNPs) associated with ten plasma FAs were used as instrumental variables. SNPs in or close to the FADS1 gene were associated with most FAs. We performed a secondary analysis of the association between a functional variant (rs174547) in FADS1, which encodes Delta 5-desaturase (a key enzyme in the endogenous FA synthesis), and CVD. Genetic predisposition to higher plasma alpha-linolenic, linoleic, and oleic acid levels was associated with lower odds of large-artery stroke and venous thromboembolism, whereas higher arachidonic and stearic acid levels were associated with higher odds of these two CVDs. The associations were driven by SNPs in or close to FADS1. In the secondary analysis, the minor allele of rs174547 in FADS1 was associated with significantly lower odds of any ischemic stroke, large-artery stroke, and venous thromboembolism and showed suggestive evidence of inverse association with coronary artery disease, abdominal aortic aneurysm and aortic valve stenosis. Genetically higher plasma alpha-linolenic, linoleic, and oleic acid levels are inversely associated with large-artery stroke and venous thromboembolism, whereas arachidonic and stearic acid levels are positively associated with these CVDs. The associations were driven by FADS1, which was also associated with other CVDs.

Weight gain can creep up on us. Over the winter months we enjoy foods that create a feeling of comfort and warmth. Many of these foods tend to be higher in calories, usually from fat or added sugars. As we enter the summer months, some of us start to think about getting in shape - and how we're going to look in a bathing costume. These concerns might be met with the temptation to seek a "quick fix" to weight loss. But this sort of approach is likely to mean finding yourself back in the same position this time next year. Looking past the quick fix and fad diets to longer-term solutions will improve your chance of keeping the weight off and staying healthy all year round.

Background: Dietary and endogenously formed long-chain polyunsaturated fatty acids (LCPUFAs) are hypothesized to improve cognitive development, but results are inconclusive, with suggestions of sex specificity. One study suggested that single-nucleotide polymorphisms (SNPs) rs1535 and rs174448 in the fatty acid desaturase (FADS) gene cluster have opposite effects on erythrocyte LCPUFAs at 9 mo.Objective: To explore whether SNPs in FADS and elongase (ELOVL) genes were associated with school performance in a sex-specific manner, we performed a Mendelian randomization study using data from the Optimal well-being, development and health for Danish children through a healthy New Nordic Diet (OPUS) School Meal Study with 765 Danish schoolchildren 8-11 y old.Design: Associations between selected FADS1/2 SNPs (rs1535, rs174448, and rs174468) and ELOVL5 rs2397142, whole-blood fatty acid composition, and performance in the d2 Test of Attention and a reading test were analyzed in multiple regression models including all SNPs, SNP-sex interactions, and covariates related to testing conditions.Results:FADS, rs1535 minor allele carriage associated with lower whole-blood arachidonic acid (P ≤ 0.002), and minor alleles of rs174448 tended to associate with lower docosahexaenoic acid (DHA) (P = 0.052). We identified sex interactions in 50% of the SNP performance sets. Sex-dependent associations were observed for rs174448 and rs1535 on the d2 Test of Attention outcomes (P < 0.03) and for the associations between reading scores and rs174448 and rs2397142 (P < 0.01). All of the sex-specific analyses showed associations in opposite directions in girls and boys. The minor allele carriage of rs174448 was associated with lower d2 Test of Attention performance (P < 0.02) and reading scores (P < 0.001) in boys but with better reading scores in girls (P ≤ 0.002). The associations were consistently the opposite for rs1535 minor allele carriage (P < 0.05). Associations with rs2

The Fishing Industry in the Philippines plays an important role in the food and employment need of Filipino fishers. By using anchored Fish Aggregating Devices (FADs or payao), the Philippine tuna fisheries was transformed into a million-dollar industry. Minimal studies on exploitation rates and fish behavior around anchored FADs hampered further understanding of this fishery practice. Studies on fish behavior using Local Ecological Knowledge (LEK) are good complement where data is limited. A study using semi-structured interview (n = 46) and three focus group discussions (n = 39 participants) to record fishers' knowledge and observations on the behavior of different fish species around anchored FADs was conducted. This particularly focused on attraction, retention, and departure behavior of fishes in identified FAD sites. Based on the fishers' knowledge, tuna schools are attracted to anchored FADs at 10 km distance. In anchored FADs, tuna form schools segregated by species and size. There was no relationship between the attraction distance and the reported school size and the various waiting times for fish to aggregate below the FADs. There was no variation between the species present at day or night time although fishers have reported a distinction of species found near the surface (0-10 m) and those found at other depths (11-20 m). Juvenile yellowfin tuna (Thunnus albacares), skipjack (Katsuwonus pelamis), and frigate and bullet tunas (Auxis spp.) are found to stay at 25-50 m from the FAD at a depth of >20 m. Adult oceanic tunas reside in deeper waters (75 m). The fish visual census produced similar results with the semi-structured interviews and FGDs but did not observe oceanic tunas at depths of 15-20 m in the anchored FADs examined.

Exposure to polyunsaturated fatty acids (PUFA) influences immune function and may affect the risk of allergy development. Long chain PUFAs are produced from dietary precursors catalyzed by desaturases and elongases encoded by FADS and ELOVL genes. In 211 subjects, we investigated whether polymorphisms in the FADS gene cluster and the ELOVL2 gene were associated with allergy or PUFA composition in serum phospholipids in a Swedish birth-cohort sampled at birth and at 13 years of age; allergy was diagnosed at 13 years of age. Minor allele carriers of rs102275 and rs174448 (FADS gene cluster) had decreased proportions of 20:4 n-6 in cord and adolescent serum and increased proportions of 20:3 n-6 in cord serum as well as a nominally reduced risk of developing atopic eczema, but not respiratory allergy, at 13 years of age. Minor allele carriers of rs17606561 in the ELOVL2 gene had nominally decreased proportions of 20:4 n-6 in cord serum but ELOVL polymorphisms (rs2236212 and rs17606561) were not associated with allergy development. Thus, reduced capacity to desaturase n-6 PUFAs due to FADS polymorphisms was nominally associated with reduced risk for eczema development, which could indicate a pathogenic role for long-chain PUFAs in allergy development.

Exposure to polyunsaturated fatty acids (PUFA) influences immune function and may affect the risk of allergy development. Long chain PUFAs are produced from dietary precursors catalyzed by desaturases and elongases encoded by FADS and ELOVL genes. In 211 subjects, we investigated whether polymorphisms in the FADS gene cluster and the ELOVL2 gene were associated with allergy or PUFA composition in serum phospholipids in a Swedish birth-cohort sampled at birth and at 13 years of age; allergy was diagnosed at 13 years of age. Minor allele carriers of rs102275 and rs174448 (FADS gene cluster) had decreased proportions of 20:4 n-6 in cord and adolescent serum and increased proportions of 20:3 n-6 in cord serum as well as a nominally reduced risk of developing atopic eczema, but not respiratory allergy, at 13 years of age. Minor allele carriers of rs17606561 in the ELOVL2 gene had nominally decreased proportions of 20:4 n-6 in cord serum but ELOVL polymorphisms (rs2236212 and rs17606561) were not associated with allergy development. Thus, reduced capacity to desaturase n-6 PUFAs due to FADS polymorphisms was nominally associated with reduced risk for eczema development, which could indicate a pathogenic role for long-chain PUFAs in allergy development.

Exposure to polyunsaturated fatty acids (PUFA) influences immune function and may affect the risk of allergy development. Long chain PUFAs are produced from dietary precursors catalyzed by desaturases and elongases encoded by FADS and ELOVL genes. In 211 subjects, we investigated whether polymorphisms in the FADS gene cluster and the ELOVL2 gene were associated with allergy or PUFA composition in serum phospholipids in a Swedish birth-cohort sampled at birth and at 13 years of age; allergy was diagnosed at 13 years of age. Minor allele carriers of rs102275 and rs174448 (FADS gene cluster) had decreased proportions of 20:4 n-6 in cord and adolescent serum and increased proportions of 20:3 n-6 in cord serum as well as a nominally reduced risk of developing atopic eczema, but not respiratory allergy, at 13 years of age. Minor allele carriers of rs17606561 in the ELOVL2 gene had nominally decreased proportions of 20:4 n-6 in cord serum but ELOVL polymorphisms (rs2236212 and rs17606561) were not associated with allergy development. Thus, reduced capacity to desaturase n-6 PUFAs due to FADS polymorphisms was nominally associated with reduced risk for eczema development, which could indicate a pathogenic role for long-chain PUFAs in allergy development.

The objective of the present study was to test for associations between changes in fatty acids (FAs) and changes in plasma triglyceride (TG) levels after an n-3 FA supplementation and to test whether SNPs from the FADS gene cluster were associ-ated with plasma FA levels or with specific FA patterns. A total of 210 subjects completed a 2-wk run-in period followed by 6-wk supplementation with 5g/d of fish oil. FA profiles of plasma phospholipids (PPLs) were obtained and 19 SNPs from the FADS gene cluster were genotyped. Principal component analysis was conducted and scores were calculated. There was an increase in EPA, DPA and DHA levels in PPLs as well as a decrease in ALA and all n-6 FA levels after the supplementa-tion. Factor analysis suggested 4 post-n-3 FA supplementation patterns. Changes in AA, ALA, DGLA, as well as changes in total n-3 and omega-6 FAs in absolute quantities of FAs were all associated with a change in TG levels whereas the cor-relation remained significant only for AA and DGLA when FAs were expressed as percentage of total FAs. Several SNPs from the FADS gene cluster were associated with post-supplementation FA levels. These results suggest that FAs alone or regrouped in factors could play a role in modulating plasma TG levels after fish oil supplementation. SNPs from the FADSgene cluster interact with both FAs and/or factors to modulate TG levels.

ADS (Air Data Sensor) measurements on HYFLEX (Hypersonic Flight Experiment) were performed. FADS (Flush Air Data System) was used because the conventional ADS like a Pitot static tube, can not be used in hypersonic flights. The objective of the ADS measurements on HYFLEX was to confirm the capability of FADS in hypersonic flights and get the fundamental data for research. ADS on HYFLEX consisted of nine flush orifices, each of which was led to an absolute pressure transducer. These orifices are suitably located on the C/C (Carbon/Carbon composite) nose cap. Only the pressure measurements were carried out during the flight. All pressure measurements were successful. The air data were obtained from the measured pressure data and compared with the air data, estimated from other devices. This paper presents the concept of ADS on HYFLEX, the data analyzing method and the associated results., HYFLEX(極超音速飛行実験)においてADS(大気データセンサ)計測を実施した。本飛行実験では、極超音速飛行であるため通常のピトー管方式のADSは使用できないので、FADS(フラッシュ大気データシステム)方式を採用した。本計測は極超音速飛行におけるFADSの能力を確認し、研究のための基礎的なデータを取得することを目的とした。ADSのためHYFLEXのC/C(カーボン/カーボン複合材)ノーズキャップ上に9つのフラッシュ型圧力ポートを適切に配置し、各ポートを絶対圧力変換器に導き、飛行中は圧力計測だけを行なった。圧力計測は全て正常に取得された。実測圧力データから飛行データを求めて、他の装置からの推定値と比較した。本論文ではHYFLEXに搭載したADSの概要、データ解析手法、解析結果について報告する。

Quinoa is an Andean pseudo-grain that has been rapidly incorporated into the lives and diets of Americans in the last twenty years. The majority of Americans see it as a superfood that has the ability to help the population of the United States with issues of health and nutrition, yet quinoa is expensive and the price is constantly rising. In the United States, quinoa is portrayed as the ultimate health food, accented by its non-U.S. origins. This thesis considers how quinoa has been incorporated into the local diets of residents of Central Pennsylvania, a primarily rural agricultural area with a large working class population and a growing population of educated professionals, due to several universities and a major medical center in the area . Central Pennsylvania is home to numerous natural food stores and locally owned restaurants that pride themselves on natural, local and fresh ingredients. However, one of the major stores in the area is Walmart, which typically attracts customers earning a lower income and yet is also selling unprocessed and organic quinoa. During 2014-2015, I conducted field research and interviews in order to understand how North Americans view quinoa in terms of its symbolic importance as a health food and a marker of social and economic class in light of its recent and rapid incorporation into United States diets. My informants, Bucknell students, professors, and Lewisburg locals, consider quinoa to be a food that mirrors class divisions in the United States. This is displayed through the attainment of beauty and healthy living in relation to class. They perceive it as a food in high demand in more affluent areas, as those with a higher income have the ability to keep up with the health trends and the foods that make healthy living possible. Nevertheless, in Central Pennsylvania where the majority of the population earns a lower income, the trend of quinoa as a class divided food can be seen as well, because the non-rich also eat quinoa e

Exposure to polyunsaturated fatty acids (PUFA) influences immune function and may affect the risk of allergy development. Long chain PUFAs are produced from dietary precursors catalyzed by desaturases and elongases encoded by FADS and ELOVL genes. In 211 subjects, we investigated whether polymorphisms in the FADS gene cluster and the ELOVL2 gene were associated with allergy or PUFA composition in serum phospholipids in a Swedish birth-cohort sampled at birth and at 13 years of age; allergy was diagnosed at 13 years of age. Minor allele carriers of rs102275 and rs174448 (FADS gene cluster) had decreased proportions of 20:4 n-6 in cord and adolescent serum and increased proportions of 20:3 n-6 in cord serum as well as a nominally reduced risk of developing atopic eczema, but not respiratory allergy, at 13 years of age. Minor allele carriers of rs17606561 in the ELOVL2 gene had nominally decreased proportions of 20:4 n-6 in cord serum but ELOVL polymorphisms (rs2236212 and rs17606561) were not associated with allergy development. Thus, reduced capacity to desaturase n-6 PUFAs due to FADS polymorphisms was nominally associated with reduced risk for eczema development, which could indicate a pathogenic role for long-chain PUFAs in allergy development.

Exposure to polyunsaturated fatty acids (PUFA) influences immune function and may affect the risk of allergy development. Long chain PUFAs are produced from dietary precursors catalyzed by desaturases and elongases encoded by FADS and ELOVL genes. In 211 subjects, we investigated whether polymorphisms in the FADS gene cluster and the ELOVL2 gene were associated with allergy or PUFA composition in serum phospholipids in a Swedish birth-cohort sampled at birth and at 13 years of age; allergy was diagnosed at 13 years of age. Minor allele carriers of rs102275 and rs174448 (FADS gene cluster) had decreased proportions of 20:4 n-6 in cord and adolescent serum and increased proportions of 20:3 n-6 in cord serum as well as a nominally reduced risk of developing atopic eczema, but not respiratory allergy, at 13 years of age. Minor allele carriers of rs17606561 in the ELOVL2 gene had nominally decreased proportions of 20:4 n-6 in cord serum but ELOVL polymorphisms (rs2236212 and rs17606561) were not associated with allergy development. Thus, reduced capacity to desaturase n-6 PUFAs due to FADS polymorphisms was nominally associated with reduced risk for eczema development, which could indicate a pathogenic role for long-chain PUFAs in allergy development.

In this project we present, first, a new mechanism to find patterns in memory accesses and then compress them achieving compress ratios higher than 200x without compromising decompression performance. We also present a new methodology to drive simulations reproducing with 100% accuracy an execution.

We hypothesize the existence of a slow-moving fad component in art prices. Using unique panel survey data on art market participants’ confidence levels in the outlook for a set of artists, we find that sentiment indeed predicts short-term returns.

Fish aggregating devices, or FADs, are used widely in developing countries to concentrate pelagic fish, making them easier to catch. Nearshore FADs anchored close to the coast allow access for rural communities, but despite their popularity among policy makers, there is a dearth of empirical analysis of their contributions to the supply of fish and to fisheries management. In this paper we demonstrate that nearshore FADs increased the supply of fish to four communities in Solomon Islands. Estimated total annual fish catch ranged from 4300 to 12 000 kg across the study villages, with nearshore FADs contributing up to 45% of the catch. While it is clear that FADs increased the supply of fish, FAD catch rates were not consistently higher than other fishing grounds. Villages with limited access to diverse or productive fishing grounds seemingly utilized FADs to better effect. Villagers believed FADs increased household income and nutrition, as well as providing a source of fish for community events. FADs were also perceived to increase intrahousehold conflict and reduce fishers' participation in community activities. FADs need to be placed within a broader rural development context and treated as another component in the diversified livelihoods of rural people; as with other livelihood options they bring trade-offs and risks.

In this effort was developed a high temperature 1-D solver to reconstruct the Longshot wind tunnel conditions. It supports calorically imperfect, thermally perfect flows in thermal equilibrium or non-equilibrium. For non-equilibrium in the Longshot, the vibrational temperature has to be imposed. A prediction was obtained by solving Vibrational-Translational Energy Transfer and energy conservation equations for the Longshot nozzle geometry. Compared to the traditional rebuilding method, thermal nonequilibrium has a strong effect on the reconstructed density and Mach number of up to 6% and 4% respectively. Caloric imperfection had a more limited effect of up to 1% and 0,4% respectively. These results indicate that better understanding of thermal non-equilibrium due to the strong nozzle expansion is required to use the wind tunnel as a FADS calibration tool. Specifically, prior knowledge of the vibrational temperature is required. Caloric imperfections need to be taken into account to reconstruct the flow conditions as well, but this requires no prior knowledge., The original document contains color images.

A central area of research in linguistics is the study of changes in vocabulary over time, be it over historical time periods or faster changes within generations. One contributing factor driving such fast changes could be “fashion cycles”, as this is a very general cultural phenomenon. Here, results are reported from a corpus study investigating trends over time in the use of cyber as the first part of compound nouns, and of alternatives which carry a similar meaning, such as e- as short for electronic. It is found that cyber was commonly used in the time period 1995-2004. Usage then strongly declined, but there was a new peak in popularity in the last year of available data (2012). Interestingly, cyber was initially used in positively charged or neutral contexts (e.g. cyberspace), but in recent years mostly in negatively charged words such as cyberbullying or cyber warfare. The hypothesis that cyber has been replaced with e- was partially supported (in particular in the case of e-mail, but e-books is another prominent example of a recent rising trend in vocabulary). However, in most other contexts usage of e- actually peaked a few years before the last years of the available corpus data. In general, results were consistent with “fashion cycles” in that the popularity of using cyber or e-, and in particular of specific words including these compound noun parts, seems to come and go rapidly over time. Interestingly use of cyber was seen mostly in negative contexts during later time periods. No such change was apparent in the use of e-. An emerging hypothesis partially supported by the data is that words in commercial contexts (e.g. cyber-business, e-business) rapidly lose their positive charge as they become common and are replaced by other, more novel and more fashionable words. Corpus linguistics is a very powerful tool for investigating such patterns of change in the popularity of words, and the processes behind them.

Tropical tunas associate with objects floating at the surface of the ocean, a behavior widely exploited by fishers. However, the respective roles played by environmental variables and behavioral processes (e.g. social behavior) in the formation of these aggregations remain elusive. To investigate the role of social behavior in the dynamics of such aggregations, we used the binary choice approach. The experimental design comprised two close and identical anchored fish aggregating devices (FADs) equipped with an echo sounder buoy to monitor the aggregated biomass of tuna under each device. Analysis of the results entailed characterizing whether the aggregated biomass is distributed asymmetrically (indicative of social behavior playing a role in the dynamics) or symmetrically between the two close and identical FADs, and comparing the results with theoretical distributions based on different definitions of basic units (individual fish or small schools). The results suggest that social interactions underlie aggregation processes, which represents a major advance in our understanding of these aggregations, a priority for science-based fishery management. While recognizing the logistical and technical constraints, we encourage the development of experimental studies (e.g. in which animals are presented with controlled situations) to enhance our understanding of the behavior of large pelagic fish. © 2013 Elsevier B.V., SCOPUS: ar.j, info:eu-repo/semantics/published

A central area of research in linguistics is the study of changes in vocabulary over time, be it over historical time periods or faster changes within generations. One contributing factor driving such fast changes could be “fashion cycles”, as this is a very general cultural phenomenon. Here, results are reported from a corpus study investigating trends over time in the use of cyber as the first part of compound nouns, and of alternatives which carry a similar meaning, such as e- as short for electronic. It is found that cyber was commonly used in the time period 1995-2004. Usage then strongly declined, but there was a new peak in popularity in the last year of available data (2012). Interestingly, cyber was initially used in positively charged or neutral contexts (e.g. cyberspace), but in recent years mostly in negatively charged words such as cyberbullying or cyber warfare. The hypothesis that cyber has been replaced with e- was partially supported (in particular in the case of e-mail, but e-books is another prominent example of a recent rising trend in vocabulary). However, in most other contexts usage of e- actually peaked a few years before the last years of the available corpus data. In general, results were consistent with “fashion cycles” in that the popularity of using cyber or e-, and in particular of specific words including these compound noun parts, seems to come and go rapidly over time. Interestingly use of cyber was seen mostly in negative contexts during later time periods. No such change was apparent in the use of e-. An emerging hypothesis partially supported by the data is that words in commercial contexts (e.g. cyber-business, e-business) rapidly lose their positive charge as they become common and are replaced by other, more novel and more fashionable words. Corpus linguistics is a very powerful tool for investigating such patterns of change in the popularity of words, and the processes behind them.

Tropical tunas associate with objects floating at the surface of the ocean, a behavior widely exploited by fishers. However, the respective roles played by environmental variables and behavioral processes (e.g. social behavior) in the formation of these aggregations remain elusive. To investigate the role of social behavior in the dynamics of such aggregations, we used the binary choice approach. The experimental design comprised two close and identical anchored fish aggregating devices (FADs) equipped with an echo sounder buoy to monitor the aggregated biomass of tuna under each device. Analysis of the results entailed characterizing whether the aggregated biomass is distributed asymmetrically (indicative of social behavior playing a role in the dynamics) or symmetrically between the two close and identical FADs, and comparing the results with theoretical distributions based on different definitions of basic units (individual fish or small schools). The results suggest that social interactions underlie aggregation processes, which represents a major advance in our understanding of these aggregations, a priority for science-based fishery management. While recognizing the logistical and technical constraints, we encourage the development of experimental studies (e.g. in which animals are presented with controlled situations) to enhance our understanding of the behavior of large pelagic fish. © 2013 Elsevier B.V., SCOPUS: ar.j, info:eu-repo/semantics/published

Background: The protective effect of breastfeeding (BF) on the development of asthma has been widely recognized, even if not all results have been consistent. Gene variants of the FADS gene cluster have a major impact on fatty acid composition in blood and in breast milk. Therefore, we evaluated the influence of the FADS1 FADS2 gene cluster polymorphisms on the association between BF and asthma.Methods: The analysis was based on data (N = 2245) from two German prospective birth cohort studies. Information on asthma and BF during the first 6 months was collected using questionnaires completed by the parents. Logistic regression modelling was used to analyse the association between exclusive BF and ever having asthma stratified by genotype.Results: In the stratified analyses, BF for 3 or 4 months after birth had a protective effect for heterozygous and homozygous carriers of the minor allele (adjusted odds ratio between 0.37 (95% CI: 0.18–0.80) and 0.42 (95% CI: 0.20–0.88). Interaction terms of BF with genotype were significant and ranged from −1.17 (P-value: 0.015) to −1.33 (0.0066). Moreover, heterozygous and homozygous carriers of the minor allele who were exclusively breastfed for 5 or 6 months after birth had a reduced risk of asthma [0.32 (0.18–0.57) to 0.47 (0.27–0.81)] in the stratified analyses. For individuals carrying the homozygous major allele, BF showed no significant effect on the development of asthma.

This thesis project is a collection of articles that discuss American fashion during the 20th century. The articles are grouped by decade, starting in the year 1900 and finishing in the year 2000; with a double-decade piece for the beginning of the century. Fashion is an ever-changing, growing entity that connects with every person in the United States; some embrace it while others ignore it, yet fashion has a place in the American society that is constant. Through world wars and depressions, fashion takes on revolutionary hardships and transforms itself accordingly, becoming selections of style that fit every occasion, taste, and social standard. What happens in society is demonstrated in fashion. Coco Chanel quoted, "fashion is always of the time in which you live." These articles correspond to and represent that.

Fatty acids (FA) have been applied as indicators of the influence of coastal sea-cage fish farming on wild fish communities in several recent scientific publications. Due to the relatively high conservation of FA composition throughout the food web, they are useful for characterizing trophic relationships. The increasing utilization of vegetable or alternative animal oils in the production of aquafeeds results in cultivated fish exhibiting higher levels of terrestrial FAs in their tissues. As previously reported, wild fish ubiquitously aggregate around fish farms as a consequence of the introduction of new habitat and the easy availability of food—fish farms act as enhanced fish aggregation devices (FADs). The influence of food pellets on the composition of wild fish has been detected in recent studies on salmon, sea bass and sea bream aquaculture, with increased levels of linoleic acid (18:2n-6) and a low n-3/n-6 ratio as clear indicators of the consumption of food pellets from the farms. The potential ecological and physiological effects on wild fish are presently unknown. In the present article, guidelines are proposed for the investigation and use of terrestrial FAs to track the effects of coastal aquaculture on wild fish communities and local fisheries, as well as the benefits or limitations of this technique.

This thesis project is a collection of articles that discuss American fashion during the 20th century. The articles are grouped by decade, starting in the year 1900 and finishing in the year 2000; with a double-decade piece for the beginning of the century. Fashion is an ever-changing, growing entity that connects with every person in the United States; some embrace it while others ignore it, yet fashion has a place in the American society that is constant. Through world wars and depressions, fashion takes on revolutionary hardships and transforms itself accordingly, becoming selections of style that fit every occasion, taste, and social standard. What happens in society is demonstrated in fashion. Coco Chanel quoted, "fashion is always of the time in which you live." These articles correspond to and represent that.

This thesis project is a collection of articles that discuss American fashion during the 20th century. The articles are grouped by decade, starting in the year 1900 and finishing in the year 2000; with a double-decade piece for the beginning of the century. Fashion is an ever-changing, growing entity that connects with every person in the United States; some embrace it while others ignore it, yet fashion has a place in the American society that is constant. Through world wars and depressions, fashion takes on revolutionary hardships and transforms itself accordingly, becoming selections of style that fit every occasion, taste, and social standard. What happens in society is demonstrated in fashion. Coco Chanel quoted, "fashion is always of the time in which you live." These articles correspond to and represent that.

This thesis project is a collection of articles that discuss American fashion during the 20th century. The articles are grouped by decade, starting in the year 1900 and finishing in the year 2000; with a double-decade piece for the beginning of the century. Fashion is an ever-changing, growing entity that connects with every person in the United States; some embrace it while others ignore it, yet fashion has a place in the American society that is constant. Through world wars and depressions, fashion takes on revolutionary hardships and transforms itself accordingly, becoming selections of style that fit every occasion, taste, and social standard. What happens in society is demonstrated in fashion. Coco Chanel quoted, "fashion is always of the time in which you live." These articles correspond to and represent that.

This thesis project is a collection of articles that discuss American fashion during the 20th century. The articles are grouped by decade, starting in the year 1900 and finishing in the year 2000; with a double-decade piece for the beginning of the century. Fashion is an ever-changing, growing entity that connects with every person in the United States; some embrace it while others ignore it, yet fashion has a place in the American society that is constant. Through world wars and depressions, fashion takes on revolutionary hardships and transforms itself accordingly, becoming selections of style that fit every occasion, taste, and social standard. What happens in society is demonstrated in fashion. Coco Chanel quoted, "fashion is always of the time in which you live." These articles correspond to and represent that.

This thesis project is a collection of articles that discuss American fashion during the 20th century. The articles are grouped by decade, starting in the year 1900 and finishing in the year 2000; with a double-decade piece for the beginning of the century. Fashion is an ever-changing, growing entity that connects with every person in the United States; some embrace it while others ignore it, yet fashion has a place in the American society that is constant. Through world wars and depressions, fashion takes on revolutionary hardships and transforms itself accordingly, becoming selections of style that fit every occasion, taste, and social standard. What happens in society is demonstrated in fashion. Coco Chanel quoted, "fashion is always of the time in which you live." These articles correspond to and represent that.