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2. Risikowahrnehmung, Stress und Wohlbefinden von Kindern und Jugendlichen mit rheumatischen Erkrankungen während der Corona-Pandemie - Daten aus der multizentrischen KickCOVID-Studie

Author

Sengler, C, Grösch, N, Niewerth, M, Göldel, J, Holl, R, Windschall, D, Haas, JP, Dressler, F, Trauzeddel, R, Hospach, A, Weller-Heinemann, F, Warschburger, P, Minden, K, Sengler, C, Grösch, N, Niewerth, M, Göldel, J, Holl, R, Windschall, D, Haas, JP, Dressler, F, Trauzeddel, R, Hospach, A, Weller-Heinemann, F, Warschburger, P, and Minden, K

Published
2023

5. Langzeitwirksamkeit von Canakinumab bei autoinflammatorischen periodischen Syndromen - Interimsanalyse des RELIANCE-Registers

Author

Kallinich, T, Blank, N, Henes, J, Kortus-Götze, B, Oommen, PT, Pankow, A, Krickau, T, Schütz, C, Horneff, G, Foeldvari, I, Rech, J, Weller-Heinemann, F, Janda, A, Hufnagel, M, Meier, F, Dressler, F, Borte, M, Andreica, I, Wasiliew, P, Fiene, M, Windschall, D, Weber-Arden, J, Kümmerle-Deschner, JB, Kallinich, T, Blank, N, Henes, J, Kortus-Götze, B, Oommen, PT, Pankow, A, Krickau, T, Schütz, C, Horneff, G, Foeldvari, I, Rech, J, Weller-Heinemann, F, Janda, A, Hufnagel, M, Meier, F, Dressler, F, Borte, M, Andreica, I, Wasiliew, P, Fiene, M, Windschall, D, Weber-Arden, J, and Kümmerle-Deschner, JB

Published
2023

6. Führt die Langzeitbehandlung mit Canakinumab bei autoinflammatorischen periodischen Fiebersyndromen vermehrt zu Infektionen? 48-Monats-Daten des RELIANCE-Registers

Author

Kümmerle-Deschner, JB, Henes, J, Kortus-Götze, B, Oommen, PT, Pankow, A, Kallinich, T, Krickau, T, Schütz, C, Horneff, G, Foeldvari, I, Rech, J, Weller-Heinemann, F, Janda, A, Hufnagel, M, Meier, F, Dressler, F, Borte, M, Andreica, I, Wasiliew, P, Fiene, M, Windschall, D, Weber-Arden, J, Blank, N, Kümmerle-Deschner, JB, Henes, J, Kortus-Götze, B, Oommen, PT, Pankow, A, Kallinich, T, Krickau, T, Schütz, C, Horneff, G, Foeldvari, I, Rech, J, Weller-Heinemann, F, Janda, A, Hufnagel, M, Meier, F, Dressler, F, Borte, M, Andreica, I, Wasiliew, P, Fiene, M, Windschall, D, Weber-Arden, J, and Blank, N

Published
2023

7. Auswirkungen der Coronavirus-Pandemie auf Patienten mit autoinflammatorischen periodischen Syndromen unter Canakinumab-Behandlung - Interimsergebnisse aus dem RELIANCE-Register

Author

Blank, N, Kümmerle-Deschner, JB, Henes, J, Kortus-Götze, B, Oommen, PT, Pankow, A, Krickau, T, Schütz, C, Horneff, G, Foeldvari, I, Rech, J, Weller-Heinemann, F, Janda, A, Hufnagel, M, Meier, F, Dressler, F, Borte, M, Andreica, I, Wasiliew, P, Fiene, M, Windschall, D, Weber-Arden, J, Kallinich, T, Blank, N, Kümmerle-Deschner, JB, Henes, J, Kortus-Götze, B, Oommen, PT, Pankow, A, Krickau, T, Schütz, C, Horneff, G, Foeldvari, I, Rech, J, Weller-Heinemann, F, Janda, A, Hufnagel, M, Meier, F, Dressler, F, Borte, M, Andreica, I, Wasiliew, P, Fiene, M, Windschall, D, Weber-Arden, J, and Kallinich, T

Published
2023

9. Prävalenz und Korrelate von Angst- und Depressionssymptomen bei Jugendlichen und jungen Erwachsenen mit juveniler idiopathischer Arthritis (JIA): Ergebnisse aus COACH

Author

Milatz, F, Niewerth, M, Tomuscheit, J, Sengler, C, Grösch, N, Klotsche, J, Windschall, D, Kallinich, T, Dressler, F, Trauzeddel, R, Holl, RW, Foeldvari, I, Brück, N, Temming, S, Hospach, A, Warschburger, P, Berendes, R, Kümmerle-Deschner, J, Weller-Heinemann, F, Haas, JP, Müller-Stierlin, AS, Mutter, A, Meissner, T, Baumeister, H, Minden, K, Milatz, F, Niewerth, M, Tomuscheit, J, Sengler, C, Grösch, N, Klotsche, J, Windschall, D, Kallinich, T, Dressler, F, Trauzeddel, R, Holl, RW, Foeldvari, I, Brück, N, Temming, S, Hospach, A, Warschburger, P, Berendes, R, Kümmerle-Deschner, J, Weller-Heinemann, F, Haas, JP, Müller-Stierlin, AS, Mutter, A, Meissner, T, Baumeister, H, and Minden, K

Published
2023

11. Prävalenz und Korrelate von Angst- und Depressionssymptomen bei Jugendlichen und jungen Erwachsenen mit juveniler idiopathischer Arthritis (JIA): Ergebnisse aus COACH

Author

Milatz, F, Niewerth, M, Tomuscheit, J, Sengler, C, Grösch, N, Klotsche, J, Windschall, D, Kallinich, T, Dressler, F, Trauzeddel, R, Holl, RW, Foeldvari, I, Brück, N, Temming, S, Hospach, A, Warschburger, P, Berendes, R, Kümmerle-Deschner, J, Weller-Heinemann, F, Haas, JP, Müller-Stierlin, AS, Mutter, A, Meissner, T, Baumeister, H, Minden, K, Milatz, F, Niewerth, M, Tomuscheit, J, Sengler, C, Grösch, N, Klotsche, J, Windschall, D, Kallinich, T, Dressler, F, Trauzeddel, R, Holl, RW, Foeldvari, I, Brück, N, Temming, S, Hospach, A, Warschburger, P, Berendes, R, Kümmerle-Deschner, J, Weller-Heinemann, F, Haas, JP, Müller-Stierlin, AS, Mutter, A, Meissner, T, Baumeister, H, and Minden, K

Published
2023

13. Auswirkungen der Coronavirus-Pandemie auf Patienten mit autoinflammatorischen periodischen Syndromen unter Canakinumab-Behandlung - Interimsergebnisse aus dem RELIANCE-Register

Author

Blank, N, Kümmerle-Deschner, JB, Henes, J, Kortus-Götze, B, Oommen, PT, Pankow, A, Krickau, T, Schütz, C, Horneff, G, Foeldvari, I, Rech, J, Weller-Heinemann, F, Janda, A, Hufnagel, M, Meier, F, Dressler, F, Borte, M, Andreica, I, Wasiliew, P, Fiene, M, Windschall, D, Weber-Arden, J, Kallinich, T, Blank, N, Kümmerle-Deschner, JB, Henes, J, Kortus-Götze, B, Oommen, PT, Pankow, A, Krickau, T, Schütz, C, Horneff, G, Foeldvari, I, Rech, J, Weller-Heinemann, F, Janda, A, Hufnagel, M, Meier, F, Dressler, F, Borte, M, Andreica, I, Wasiliew, P, Fiene, M, Windschall, D, Weber-Arden, J, and Kallinich, T

Published
2023

15. Führt die Langzeitbehandlung mit Canakinumab bei autoinflammatorischen periodischen Fiebersyndromen vermehrt zu Infektionen? 48-Monats-Daten des RELIANCE-Registers

Author

Kümmerle-Deschner, JB, Henes, J, Kortus-Götze, B, Oommen, PT, Pankow, A, Kallinich, T, Krickau, T, Schütz, C, Horneff, G, Foeldvari, I, Rech, J, Weller-Heinemann, F, Janda, A, Hufnagel, M, Meier, F, Dressler, F, Borte, M, Andreica, I, Wasiliew, P, Fiene, M, Windschall, D, Weber-Arden, J, Blank, N, Kümmerle-Deschner, JB, Henes, J, Kortus-Götze, B, Oommen, PT, Pankow, A, Kallinich, T, Krickau, T, Schütz, C, Horneff, G, Foeldvari, I, Rech, J, Weller-Heinemann, F, Janda, A, Hufnagel, M, Meier, F, Dressler, F, Borte, M, Andreica, I, Wasiliew, P, Fiene, M, Windschall, D, Weber-Arden, J, and Blank, N

Published
2023

16. Langzeitwirksamkeit von Canakinumab bei autoinflammatorischen periodischen Syndromen - Interimsanalyse des RELIANCE-Registers

Author

Kallinich, T, Blank, N, Henes, J, Kortus-Götze, B, Oommen, PT, Pankow, A, Krickau, T, Schütz, C, Horneff, G, Foeldvari, I, Rech, J, Weller-Heinemann, F, Janda, A, Hufnagel, M, Meier, F, Dressler, F, Borte, M, Andreica, I, Wasiliew, P, Fiene, M, Windschall, D, Weber-Arden, J, Kümmerle-Deschner, JB, Kallinich, T, Blank, N, Henes, J, Kortus-Götze, B, Oommen, PT, Pankow, A, Krickau, T, Schütz, C, Horneff, G, Foeldvari, I, Rech, J, Weller-Heinemann, F, Janda, A, Hufnagel, M, Meier, F, Dressler, F, Borte, M, Andreica, I, Wasiliew, P, Fiene, M, Windschall, D, Weber-Arden, J, and Kümmerle-Deschner, JB

Published
2023

17. Risikowahrnehmung, Stress und Wohlbefinden von Kindern und Jugendlichen mit rheumatischen Erkrankungen während der Corona-Pandemie - Daten aus der multizentrischen KickCOVID-Studie

Author

Sengler, C, Grösch, N, Niewerth, M, Göldel, J, Holl, R, Windschall, D, Haas, JP, Dressler, F, Trauzeddel, R, Hospach, A, Weller-Heinemann, F, Warschburger, P, Minden, K, Sengler, C, Grösch, N, Niewerth, M, Göldel, J, Holl, R, Windschall, D, Haas, JP, Dressler, F, Trauzeddel, R, Hospach, A, Weller-Heinemann, F, Warschburger, P, and Minden, K

Published
2023

19. When Internet of Things Meets Metaverse: Convergence of Physical and Cyber Worlds

Author

Li, K, Cui, Y, Li, W, Lv, T, Yuan, X, Li, S, Ni, W, Simsek, M, Dressler, F, Li, K, Cui, Y, Li, W, Lv, T, Yuan, X, Li, S, Ni, W, Simsek, M, and Dressler, F

Abstract

In recent years, the Internet of Things (IoT) has been studied in the context of the Metaverse to provide users with immersive cyber-virtual experiences in mixed-reality environments. This survey introduces six typical IoT applications in the Metaverse, including collaborative healthcare, education, smart city, entertainment, real estate, and socialization. In the IoT-inspired Metaverse, we also comprehensively survey four pillar technologies that enable augmented reality (AR) and virtual reality (VR), namely, responsible artificial intelligence (AI), high-speed data communications, cost-effective mobile edge computing (MEC), and digital twins. According to the physical-world demands, we outline the current industrial efforts and seven key requirements for building the IoT-inspired Metaverse: immersion, variety, economy, civility, interactivity, authenticity, and independence. In addition, this survey describes the open issues in the IoT-inspired Metaverse, which need to be addressed to eventually achieve the convergence of physical and cyber worlds.

Published
2023

21. Depressive und ängstliche Symptome bei Patienten mit juveniler idiopathischer Arthritis (JIA) - Daten aus der Inzeptionskohorte neu diagnostizierter Kinder und Jugendlicher mit JIA (ICON)

Author

Sengler, C, Oommen, P, Klotsche, J, Berendes, R, Dressler, F, Foeldvari, I, Föll, D, Geikowski, T, Haller, M, Horneff, G, Hospach, A, Kallinich, T, Kümmerle-Deschner, J, Liedmann, I, Mönkemöller, K, Niewerth, M, Rühlmann, M, Schmalbach, T, Siemer, C, Weller-Heinemann, F, Windschall, D, Minden, K, Sengler, C, Oommen, P, Klotsche, J, Berendes, R, Dressler, F, Foeldvari, I, Föll, D, Geikowski, T, Haller, M, Horneff, G, Hospach, A, Kallinich, T, Kümmerle-Deschner, J, Liedmann, I, Mönkemöller, K, Niewerth, M, Rühlmann, M, Schmalbach, T, Siemer, C, Weller-Heinemann, F, Windschall, D, and Minden, K

Published
2022

22. Wirksamkeit und Sicherheit von IL-6-Inhibition (Tocilizumab) im Vergleich zu TNF-Inhibition bei polyartikulärer juveniler idiopathischer Arthritis: Ergebnisse aus dem BIKER-Register

Author

Klein, A, Zimmer, A, Hospach, A, Weller-Heinemann, F, Hansmann, S, Kuemmerle Deschner, J, Fasshauer, M, Minden, K, Foeldvari, I, Rietschel, C, Windschall, D, Ralf, T, Hufnagel, M, Foell, D, Berende, R, Oommen, P, Böschow, G, Dressler, F, Horneff, G, Klein, A, Zimmer, A, Hospach, A, Weller-Heinemann, F, Hansmann, S, Kuemmerle Deschner, J, Fasshauer, M, Minden, K, Foeldvari, I, Rietschel, C, Windschall, D, Ralf, T, Hufnagel, M, Foell, D, Berende, R, Oommen, P, Böschow, G, Dressler, F, and Horneff, G

Published
2022

23. Verlauf der Uveitis bei Kindern mit juveniler idiopathischer Arthritis: Daten aus der Inzeptionskohorte ICON-JIA

Author

Klotsche, J, Sengler, C, Foell, D, Foeldvari, I, Haas, JP, Horneff, G, Dressler, F, Hospach, A, Kallinich, T, Liedmann, I, Mönkemöller, K, Niewerth, M, Weller-Heinemann, F, Windschall, D, Heiligenhaus, A, Minden, K, Baquet-Walscheid, K, Klotsche, J, Sengler, C, Foell, D, Foeldvari, I, Haas, JP, Horneff, G, Dressler, F, Hospach, A, Kallinich, T, Liedmann, I, Mönkemöller, K, Niewerth, M, Weller-Heinemann, F, Windschall, D, Heiligenhaus, A, Minden, K, and Baquet-Walscheid, K

Published
2022

24. Impfsicherheit unter Canakinumab bei Patienten mit autoinflammatorischen periodischen Syndromen - Interimsanalyse des RELIANCE-Registers

Author

Kümmerle-Deschner, JB, Henes, J, Kortus-Götze, B, Kallinich, T, Oommen, PT, Rech, J, Krickau, T, Weller-Heinemann, F, Horneff, G, Janda, A, Foeldvari, I, Meier, F, Schütz, C, Dressler, F, Borte, M, Hufnagel, M, Fiene, M, Weber-Arden, J, Blank, N, Kümmerle-Deschner, JB, Henes, J, Kortus-Götze, B, Kallinich, T, Oommen, PT, Rech, J, Krickau, T, Weller-Heinemann, F, Horneff, G, Janda, A, Foeldvari, I, Meier, F, Schütz, C, Dressler, F, Borte, M, Hufnagel, M, Fiene, M, Weber-Arden, J, and Blank, N

Published
2022

25. Gesundheitsbezogene Transitionskompetenz bei Jugendlichen und jungen Erwachsenen mit juveniler idiopathischer Arthritis (JIA)

Author

Niewerth, M, Minden, K, Schalm, S, Foeldvari, I, Dollinger, S, Horneff, G, Windschall, D, Kallinich, T, Dressler, F, Weller-Heinemann, F, Berendes, R, Hospach, T, Hufnagel, M, Haller, M, Hansmann, S, Klotsche, J, Niewerth, M, Minden, K, Schalm, S, Foeldvari, I, Dollinger, S, Horneff, G, Windschall, D, Kallinich, T, Dressler, F, Weller-Heinemann, F, Berendes, R, Hospach, T, Hufnagel, M, Haller, M, Hansmann, S, and Klotsche, J

Published
2022

26. Langzeitwirksamkeit und Sicherheit von Canakinumab bei Patienten mit familiärem Mittelmeerfieber (FMF) - Zwischenanalyse des RELIANCE-Registers

Author

Henes, J, Kümmerle-Deschner, JB, Krickau, T, Kallinich, T, Dressler, F, Horneff, G, Meier, F, Foeldvari, I, Weller-Heinemann, F, Kortus-Götze, B, Hufnagel, M, Rech, J, Oommen, PT, Weber-Arden, J, Blank, N, Henes, J, Kümmerle-Deschner, JB, Krickau, T, Kallinich, T, Dressler, F, Horneff, G, Meier, F, Foeldvari, I, Weller-Heinemann, F, Kortus-Götze, B, Hufnagel, M, Rech, J, Oommen, PT, Weber-Arden, J, and Blank, N

Published
2022

27. Vehicloak: A blockchain-enabled privacy-preserving payment scheme for location-based vehicular services

Author

Guo, Y., Wan, Z., Cui, H., Cheng, X., Dressler, F., Guo, Y., Wan, Z., Cui, H., Cheng, X., and Dressler, F.

Abstract

The Internet of Vehicles (IoV) technology enables vehicles to communicate with each other, with pedestrians and with roadside infrastructures, to realize more efficient, safer and more environmentally friendly transportation. IoV also promises rich location-based services for vehicles, such as parking and toll highway. However, preserving privacy for location-based service payments emerges as a critical and challenging problem in IoV. Existing schemes rely on centralized banks for payment processing, resulting in location privacy leakage to centralized entities. In this paper, we propose a decentralized privacy-preserving payment scheme named Vehicloak for IoV based on the blockchain technology. The biggest challenge is to provide location privacy for vehicles while guaranteeing correct service payments using the transparent blockchain. To tackle this challenge, we introduce a new cryptographic technique called zk-GSigproof that integrates zero-knowledge proof with group signature. Vehicloak implements this technique in a smart contract to process payment, which verifies zero-knowledge proof and group signature without leaking location information. It is not limited to IoV and can be applied in many payment scenarios. To evaluate the performance of our scheme, we implement Vehicloak on a private blockchain of 100 nodes on Aliyun, and conduct a test with up to 4,000 transactions. The experimental results prove the feasibility of Vehicloak.

Published
2022

29. Wirksamkeit und Sicherheit von IL-6-Inhibition (Tocilizumab) im Vergleich zu TNF-Inhibition bei polyartikulärer juveniler idiopathischer Arthritis: Ergebnisse aus dem BIKER-Register

Author

Klein, A, Zimmer, A, Hospach, A, Weller-Heinemann, F, Hansmann, S, Kuemmerle Deschner, J, Fasshauer, M, Minden, K, Foeldvari, I, Rietschel, C, Windschall, D, Ralf, T, Hufnagel, M, Foell, D, Berende, R, Oommen, P, Böschow, G, Dressler, F, Horneff, G, Klein, A, Zimmer, A, Hospach, A, Weller-Heinemann, F, Hansmann, S, Kuemmerle Deschner, J, Fasshauer, M, Minden, K, Foeldvari, I, Rietschel, C, Windschall, D, Ralf, T, Hufnagel, M, Foell, D, Berende, R, Oommen, P, Böschow, G, Dressler, F, and Horneff, G

Published
2022

30. Langzeitwirksamkeit und Sicherheit von Canakinumab bei Patienten mit familiärem Mittelmeerfieber (FMF) - Zwischenanalyse des RELIANCE-Registers

Author

Henes, J, Kümmerle-Deschner, JB, Krickau, T, Kallinich, T, Dressler, F, Horneff, G, Meier, F, Foeldvari, I, Weller-Heinemann, F, Kortus-Götze, B, Hufnagel, M, Rech, J, Oommen, PT, Weber-Arden, J, Blank, N, Henes, J, Kümmerle-Deschner, JB, Krickau, T, Kallinich, T, Dressler, F, Horneff, G, Meier, F, Foeldvari, I, Weller-Heinemann, F, Kortus-Götze, B, Hufnagel, M, Rech, J, Oommen, PT, Weber-Arden, J, and Blank, N

Published
2022

31. Depressive und ängstliche Symptome bei Patienten mit juveniler idiopathischer Arthritis (JIA) - Daten aus der Inzeptionskohorte neu diagnostizierter Kinder und Jugendlicher mit JIA (ICON)

Author

Sengler, C, Oommen, P, Klotsche, J, Berendes, R, Dressler, F, Foeldvari, I, Föll, D, Geikowski, T, Haller, M, Horneff, G, Hospach, A, Kallinich, T, Kümmerle-Deschner, J, Liedmann, I, Mönkemöller, K, Niewerth, M, Rühlmann, M, Schmalbach, T, Siemer, C, Weller-Heinemann, F, Windschall, D, Minden, K, Sengler, C, Oommen, P, Klotsche, J, Berendes, R, Dressler, F, Foeldvari, I, Föll, D, Geikowski, T, Haller, M, Horneff, G, Hospach, A, Kallinich, T, Kümmerle-Deschner, J, Liedmann, I, Mönkemöller, K, Niewerth, M, Rühlmann, M, Schmalbach, T, Siemer, C, Weller-Heinemann, F, Windschall, D, and Minden, K

Published
2022

32. Impfsicherheit unter Canakinumab bei Patienten mit autoinflammatorischen periodischen Syndromen - Interimsanalyse des RELIANCE-Registers

Author

Kümmerle-Deschner, JB, Henes, J, Kortus-Götze, B, Kallinich, T, Oommen, PT, Rech, J, Krickau, T, Weller-Heinemann, F, Horneff, G, Janda, A, Foeldvari, I, Meier, F, Schütz, C, Dressler, F, Borte, M, Hufnagel, M, Fiene, M, Weber-Arden, J, Blank, N, Kümmerle-Deschner, JB, Henes, J, Kortus-Götze, B, Kallinich, T, Oommen, PT, Rech, J, Krickau, T, Weller-Heinemann, F, Horneff, G, Janda, A, Foeldvari, I, Meier, F, Schütz, C, Dressler, F, Borte, M, Hufnagel, M, Fiene, M, Weber-Arden, J, and Blank, N

Published
2022

33. Gesundheitsbezogene Transitionskompetenz bei Jugendlichen und jungen Erwachsenen mit juveniler idiopathischer Arthritis (JIA)

Author

Niewerth, M, Minden, K, Schalm, S, Foeldvari, I, Dollinger, S, Horneff, G, Windschall, D, Kallinich, T, Dressler, F, Weller-Heinemann, F, Berendes, R, Hospach, T, Hufnagel, M, Haller, M, Hansmann, S, Klotsche, J, Niewerth, M, Minden, K, Schalm, S, Foeldvari, I, Dollinger, S, Horneff, G, Windschall, D, Kallinich, T, Dressler, F, Weller-Heinemann, F, Berendes, R, Hospach, T, Hufnagel, M, Haller, M, Hansmann, S, and Klotsche, J

Published
2022

34. TRANSITION COMPETENCE IN YOUNG PEOPLE WITH JUVENILE IDIOPATHIC ARTHRITIS HAS IMPROVED OVER TIME

Author

Minden, K., Niewerth, M., Schalm, S., Foeldvari, I., Haas, J. P., Horneff, G., Windschall, D., Kallinich, T., Dressler, F., Weller-Heinemann, F., Berendes, R., Hospach, T., Hufnagel, M., Haller, M., Hansmann, S., Klotsche, J., Minden, K., Niewerth, M., Schalm, S., Foeldvari, I., Haas, J. P., Horneff, G., Windschall, D., Kallinich, T., Dressler, F., Weller-Heinemann, F., Berendes, R., Hospach, T., Hufnagel, M., Haller, M., Hansmann, S., and Klotsche, J.

Published
2022

35. EFFECTIVENESS AND SAFETY OF IL-6 INHIBITION (TOCILIZUMAB) VERSUS TUMOUR NECROSIS FACTOR INHIBITION IN POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS: RESULTS FROM THE OBSERVATIONAL BIKER STUDY

Author

Klein, A., Zimmer, A., Hospach, T., Weller-Heinemann, F., Hansmann, S., Kuemmerle-Deschner, J., Fasshauer, M., Minden, K., Foeldvari, I., Rietschel, C., Windschall, D., Trauzeddel, R., Hufnagel, M., Foell, D., Berendes, R., Boeschow, G., Oommen, P., Dressler, F., Horneff, G., Klein, A., Zimmer, A., Hospach, T., Weller-Heinemann, F., Hansmann, S., Kuemmerle-Deschner, J., Fasshauer, M., Minden, K., Foeldvari, I., Rietschel, C., Windschall, D., Trauzeddel, R., Hufnagel, M., Foell, D., Berendes, R., Boeschow, G., Oommen, P., Dressler, F., and Horneff, G.

Published
2022

36. Continuous Maneuver Control and Data Capture Scheduling of Autonomous Drone in Wireless Sensor Networks

Author

Li, K, Ni, W, Dressler, F, Li, K, Ni, W, and Dressler, F

Abstract

Thanks to flexible deployment and excellent maneuverability, autonomous drones are regarded as an effective means to enable aerial data capture in large-scale wireless sensor networks with limited to no cellular infrastructure, e.g., smart farming in a remote area. A key challenge in drone-assisted sensor networks is that the autonomous drone's maneuvering can give rise to buffer overflows at the ground sensors and unsuccessful data collection due to lossy airborne channels. In this paper, we propose a new Deep Deterministic Policy Gradient based Maneuver Control (DDPG-MC) scheme which minimizes the overall data packet loss through online training instantaneous headings and patrol velocities of the drone, and the selection of the ground sensors for data collection in a continuous action space. Moreover, the maneuver control of the drone and communication schedule is formulated as an absorbing Markov chain, where network states consist of battery energy levels, data queue backlogs, timestamps of the data collection, and channel conditions between the ground sensors and the drone. An experience replay memory is utilized onboard at the drone to store the training experiences of the maneuver control and communication schedule at each time step.

Published
2022

37. LSTM-Characterized Deep Reinforcement Learning for Continuous Flight Control and Resource Allocation in UAV-Assisted Sensor Network

Author

Li, K, Ni, W, Dressler, F, Li, K, Ni, W, and Dressler, F

Abstract

Unmanned aerial vehicles (UAVs) can be employed to collect sensory data in remote wireless sensor networks (WSNs). Due to UAV's maneuvering, scheduling a sensor device to transmit data can overflow data buffers of the unscheduled ground devices. Moreover, lossy airborne channels can result in packet reception errors at the scheduled sensor. This article proposes a new deep reinforcement learning-based flight resource allocation framework (DeFRA) to minimize the overall data packet loss in a continuous action space. DeFRA is based on deep deterministic policy gradient (DDPG), optimally controls instantaneous headings and speeds of the UAV, and selects the ground device for data collection. Furthermore, a state characterization layer, leveraging long short-term memory (LSTM), is developed to predict network dynamics, resulting from time-varying airborne channels and energy arrivals at the ground devices. To validate the effectiveness of DeFRA, experimental data collected from a real-world UAV testbed and energy harvesting WSN are utilized to train the actions of the UAV. Numerical results demonstrate that the proposed DeFRA achieves a fast convergence while reducing the packet loss by over 15%, as compared to the existing deep reinforcement learning solutions.

Published
2022

38. Outcome of children with oligoarticular juvenile idiopathic arthritis compared to polyarthritis on methotrexate- data of the German BIKER registry

Author

Raab, A., Kallinich, T., Huscher, D., Foeldvari, I., Weller-Heinemann, F., Dressler, F., Kuemmerle-Deschner, J. B., Klein, A., Horneff, G., Raab, A., Kallinich, T., Huscher, D., Foeldvari, I., Weller-Heinemann, F., Dressler, F., Kuemmerle-Deschner, J. B., Klein, A., and Horneff, G.

Abstract

BackgroundOligoarticular juvenile idiopathic arthritis (oligoJIA) is the most commonly diagnosed category of chronic arthritis in children. Nevertheless, there are no evidence- based guidelines for its treatment, in particular for the use of methotrexate (MTX). The primary objective of this analysis is to evaluate the outcomes in patients with persistent oligoJIA compared to those with extended oligoJIA and rheumatoid factor (RF) negative polyarthritis treated with methotrexate.MethodsPatients with persistent or extended oligoJIA or RF negative PA recorded in the Biologics in Pediatric Rheumatology Registry (BiKeR), receiving methotrexate for the first time were included in the analyses. Efficacy was determined using the Juvenile Arthritis Disease Activity Score 10 (JADAS 10). Safety assessment included the documentation of adverse and serious adverse events.ResultsFrom 2005 through 2011, 1056 patients were included: 370 patients with persistent oligoJIA, 221 patients with extended oligoJIA and 467 patients with RF negative PA. Therapeutic efficacy was observed following the start of methotrexate.Over a period of 24months JADAS-minimal disease activity (JADAS <= 2) was reached in 44% of patients with persistent oligoJIA, 38% with extended oligoJIA, 46% with RF negative PA, JADAS-remission defined as JADAS <= 1 was reached in 33% of patients with persistent oligoJIA, 29% with extended oligoJIA and 35% (RF negative PA). Patients with extended oligoJIA achieved JADAS remission significantly later and received additional biologic disease-modifying drugs significantly more often than patients with persistent oligoJIA or RF negative PA (p <0.001). Tolerability was comparable. New onset uveitis occurred in 0.3 to 2.2 per 100 patient years.ConclusionsPatients with persistent oligoJIA taking methotrexate are at least as likely to enter remission as patients with extended oligo JIA or polyarticular JIA. Patients with extended oligoJIA achieved JADAS remission significantly la

Published
2021

39. COMPARISON OF THREE DIFFERENT ALGORITHMS FOR THE TREATMENT OF CHILDREN WITH POLYARTICULAR JIA: THE FIRST YEAR AFTER DIAGNOSIS

Author

Minden, K., Schwarz, T., Dressler, F., Foeldvari, I., Haas, J. P., Horneff, G., Hospach, T., Kuemmerle-Deschner, J., Moenkemoeller, K., Weller-Heinemann, F., Tenbrock, K., Niewerth, M., Sengler, C., Foell, D., Klotsche, J., Minden, K., Schwarz, T., Dressler, F., Foeldvari, I., Haas, J. P., Horneff, G., Hospach, T., Kuemmerle-Deschner, J., Moenkemoeller, K., Weller-Heinemann, F., Tenbrock, K., Niewerth, M., Sengler, C., Foell, D., and Klotsche, J.

Published
2021

40. PREVALENCE AND CORRELATES OF UNDERWEIGHT, OVERWEIGHT AND OBESITY AMONG PATIENTS WITH JUVENILE IDIOPATHIC ARTHRITIS (JIA): EVIDENCE FROM THE NATIONAL PAEDIATRIC RHEUMATOLOGIC DATABASE (NPRD)

Author

Milatz, F., Klotsche, J., Niewerth, M., Hoerstermann, J., Windschall, D., Weller-Heinemann, F., Dressler, F., Berendes, R., Haas, J. P., Horneff, G., Minden, K., Milatz, F., Klotsche, J., Niewerth, M., Hoerstermann, J., Windschall, D., Weller-Heinemann, F., Dressler, F., Berendes, R., Haas, J. P., Horneff, G., and Minden, K.

Published
2021

41. Langzeitwirksamkeit und -sicherheit von Canakinumab bei Patienten mit Familiärem Mittelmeerfieber (FMF) - Interimsanalyse des RELIANCE-Registers

Author

Henes, J, Kümmerle-Deschner, J, Kallinich, T, Dressler, F, Weller-Heinemann, F, Kortus-Götze, B, Foeldvari, I, Horneff, G, Hufnagel, M, Meier, F, Weber-Arden, J, Blank, N, Henes, J, Kümmerle-Deschner, J, Kallinich, T, Dressler, F, Weller-Heinemann, F, Kortus-Götze, B, Foeldvari, I, Horneff, G, Hufnagel, M, Meier, F, Weber-Arden, J, and Blank, N

Published
2021

42. Langzeitwirksamkeit und -sicherheit von Canakinumab bei Patienten mit Familiärem Mittelmeerfieber (FMF) - Interimsanalyse des RELIANCE-Registers

Author

Henes, J, Kümmerle-Deschner, J, Kallinich, T, Dressler, F, Weller-Heinemann, F, Kortus-Götze, B, Foeldvari, I, Horneff, G, Hufnagel, M, Meier, F, Weber-Arden, J, Blank, N, Henes, J, Kümmerle-Deschner, J, Kallinich, T, Dressler, F, Weller-Heinemann, F, Kortus-Götze, B, Foeldvari, I, Horneff, G, Hufnagel, M, Meier, F, Weber-Arden, J, and Blank, N

Published
2021

43. COMPARISON OF THREE DIFFERENT ALGORITHMS FOR THE TREATMENT OF CHILDREN WITH POLYARTICULAR JIA: THE FIRST YEAR AFTER DIAGNOSIS

Author

Minden, K., Schwarz, T., Dressler, F., Foeldvari, I., Haas, J. P., Horneff, G., Hospach, T., Kuemmerle-Deschner, J., Moenkemoeller, K., Weller-Heinemann, F., Tenbrock, K., Niewerth, M., Sengler, C., Foell, D., Klotsche, J., Minden, K., Schwarz, T., Dressler, F., Foeldvari, I., Haas, J. P., Horneff, G., Hospach, T., Kuemmerle-Deschner, J., Moenkemoeller, K., Weller-Heinemann, F., Tenbrock, K., Niewerth, M., Sengler, C., Foell, D., and Klotsche, J.

Published
2021

44. Outcome of children with oligoarticular juvenile idiopathic arthritis compared to polyarthritis on methotrexate- data of the German BIKER registry

Author

Raab, A., Kallinich, T., Huscher, D., Foeldvari, I., Weller-Heinemann, F., Dressler, F., Kuemmerle-Deschner, J. B., Klein, A., Horneff, G., Raab, A., Kallinich, T., Huscher, D., Foeldvari, I., Weller-Heinemann, F., Dressler, F., Kuemmerle-Deschner, J. B., Klein, A., and Horneff, G.

Abstract

BackgroundOligoarticular juvenile idiopathic arthritis (oligoJIA) is the most commonly diagnosed category of chronic arthritis in children. Nevertheless, there are no evidence- based guidelines for its treatment, in particular for the use of methotrexate (MTX). The primary objective of this analysis is to evaluate the outcomes in patients with persistent oligoJIA compared to those with extended oligoJIA and rheumatoid factor (RF) negative polyarthritis treated with methotrexate.MethodsPatients with persistent or extended oligoJIA or RF negative PA recorded in the Biologics in Pediatric Rheumatology Registry (BiKeR), receiving methotrexate for the first time were included in the analyses. Efficacy was determined using the Juvenile Arthritis Disease Activity Score 10 (JADAS 10). Safety assessment included the documentation of adverse and serious adverse events.ResultsFrom 2005 through 2011, 1056 patients were included: 370 patients with persistent oligoJIA, 221 patients with extended oligoJIA and 467 patients with RF negative PA. Therapeutic efficacy was observed following the start of methotrexate.Over a period of 24months JADAS-minimal disease activity (JADAS <= 2) was reached in 44% of patients with persistent oligoJIA, 38% with extended oligoJIA, 46% with RF negative PA, JADAS-remission defined as JADAS <= 1 was reached in 33% of patients with persistent oligoJIA, 29% with extended oligoJIA and 35% (RF negative PA). Patients with extended oligoJIA achieved JADAS remission significantly later and received additional biologic disease-modifying drugs significantly more often than patients with persistent oligoJIA or RF negative PA (p <0.001). Tolerability was comparable. New onset uveitis occurred in 0.3 to 2.2 per 100 patient years.ConclusionsPatients with persistent oligoJIA taking methotrexate are at least as likely to enter remission as patients with extended oligo JIA or polyarticular JIA. Patients with extended oligoJIA achieved JADAS remission significantly la

Published
2021

45. PREVALENCE AND CORRELATES OF UNDERWEIGHT, OVERWEIGHT AND OBESITY AMONG PATIENTS WITH JUVENILE IDIOPATHIC ARTHRITIS (JIA): EVIDENCE FROM THE NATIONAL PAEDIATRIC RHEUMATOLOGIC DATABASE (NPRD)

Author

Milatz, F., Klotsche, J., Niewerth, M., Hoerstermann, J., Windschall, D., Weller-Heinemann, F., Dressler, F., Berendes, R., Haas, J. P., Horneff, G., Minden, K., Milatz, F., Klotsche, J., Niewerth, M., Hoerstermann, J., Windschall, D., Weller-Heinemann, F., Dressler, F., Berendes, R., Haas, J. P., Horneff, G., and Minden, K.

Published
2021

46. Langzeitüberwachung der Sicherheit von Biologikatherapien bei systemischer juveniler idiopathischer Arthritis

Author

Klein, A, Klotsche, J, Dressler, F, Trauzeddel, R, Minden, K, Hospach, A, Rietschel, C, Rühlmann, M, Weller-Heinemann, F, Lilienthal, E, Sailer-Höck, M, Hufnagel, M, Urban, A, Ganser, G, Emminger, W, Hügle, B, Hansmann, S, Horneff, G, Klein, A, Klotsche, J, Dressler, F, Trauzeddel, R, Minden, K, Hospach, A, Rietschel, C, Rühlmann, M, Weller-Heinemann, F, Lilienthal, E, Sailer-Höck, M, Hufnagel, M, Urban, A, Ganser, G, Emminger, W, Hügle, B, Hansmann, S, and Horneff, G

Published
2019

49. Langzeitüberwachung der Sicherheit von Biologikatherapien bei systemischer juveniler idiopathischer Arthritis

Author

Klein, A, Klotsche, J, Dressler, F, Trauzeddel, R, Minden, K, Hospach, A, Rietschel, C, Rühlmann, M, Weller-Heinemann, F, Lilienthal, E, Sailer-Höck, M, Hufnagel, M, Urban, A, Ganser, G, Emminger, W, Hügle, B, Hansmann, S, Horneff, G, Klein, A, Klotsche, J, Dressler, F, Trauzeddel, R, Minden, K, Hospach, A, Rietschel, C, Rühlmann, M, Weller-Heinemann, F, Lilienthal, E, Sailer-Höck, M, Hufnagel, M, Urban, A, Ganser, G, Emminger, W, Hügle, B, Hansmann, S, and Horneff, G

Published
2019

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