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8 results on '"DYKEN, M"'

1. Selective potentiation of peripheral chemoreflex sensitivity in obstructive sleep apnea.

Author

Narkiewicz, K, Van De Borne, Philippe, Pesek, C A, Dyken, M E, Montano, Nicola, Somers, Virend Kristen, Narkiewicz, K, Van De Borne, Philippe, Pesek, C A, Dyken, M E, Montano, Nicola, and Somers, Virend Kristen

Abstract

The chemoreflexes are an important mechanism for regulation of both breathing and autonomic cardiovascular function. Abnormalities in chemoreflex mechanisms may be implicated in increased cardiovascular stress in patients with obstructive sleep apnea (OSA). We tested the hypothesis that chemoreflex function is altered in patients with OSA., Clinical Trial, Controlled Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S., info:eu-repo/semantics/published

Published
1999

2. Selective potentiation of peripheral chemoreflex sensitivity in obstructive sleep apnea.

Author

Narkiewicz, K, Van De Borne, Philippe, Pesek, C A, Dyken, M E, Montano, Nicola, Somers, Virend Kristen, Narkiewicz, K, Van De Borne, Philippe, Pesek, C A, Dyken, M E, Montano, Nicola, and Somers, Virend Kristen

Abstract

The chemoreflexes are an important mechanism for regulation of both breathing and autonomic cardiovascular function. Abnormalities in chemoreflex mechanisms may be implicated in increased cardiovascular stress in patients with obstructive sleep apnea (OSA). We tested the hypothesis that chemoreflex function is altered in patients with OSA., Clinical Trial, Controlled Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S., info:eu-repo/semantics/published

Published
1999

3. Contribution of tonic chemoreflex activation to sympathetic activity and blood pressure in patients with obstructive sleep apnea.

Author

Narkiewicz, K, Van De Borne, Philippe, Montano, Nicola, Dyken, M E, Phillips, B G, Somers, Virend Kristen, Narkiewicz, K, Van De Borne, Philippe, Montano, Nicola, Dyken, M E, Phillips, B G, and Somers, Virend Kristen

Abstract

Muscle sympathetic nerve activity (MSNA) is increased in patients with obstructive sleep apnea (OSA). We tested the hypothesis that tonic activation of excitatory chemoreceptor afferents contributes to the elevated sympathetic activity in OSA., Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S., info:eu-repo/semantics/published

Published
1998

4. Altered cardiovascular variability in obstructive sleep apnea.

Author

Narkiewicz, K, Montano, Nicola, Cogliati, C, Van De Borne, Philippe, Dyken, M E, Somers, Virend Kristen, Narkiewicz, K, Montano, Nicola, Cogliati, C, Van De Borne, Philippe, Dyken, M E, and Somers, Virend Kristen

Abstract

Altered cardiovascular variability is a prognostic indicator for cardiovascular events. Patients with obstructive sleep apnea (OSA) are at an increased risk for cardiovascular disease. We tested the hypothesis that OSA is accompanied by alterations in cardiovascular variability, even in the absence of overt cardiovascular disease., Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S., info:eu-repo/semantics/published

Published
1998

5. Sympathetic activity in obese subjects with and without obstructive sleep apnea.

Author

Narkiewicz, K, Van De Borne, Philippe, Cooley, R L, Dyken, M E, Somers, Virend Kristen, Narkiewicz, K, Van De Borne, Philippe, Cooley, R L, Dyken, M E, and Somers, Virend Kristen

Abstract

Obese humans are reported to have increased muscle sympathetic nerve activity (MSNA). Obstructive sleep apnea (OSA) may also be accompanied by increased MSNA. Because there is a high prevalence of OSA in obese humans, it is possible that high MSNA reported in obese subjects may in fact reflect the presence of OSA in these subjects. We tested the hypothesis that obesity, per se, in the absence of OSA, is not accompanied by increased MSNA., Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S., info:eu-repo/semantics/published

Published
1998

6. Contribution of tonic chemoreflex activation to sympathetic activity and blood pressure in patients with obstructive sleep apnea.

Author

Narkiewicz, K, Van De Borne, Philippe, Montano, Nicola, Dyken, M E, Phillips, B G, Somers, Virend Kristen, Narkiewicz, K, Van De Borne, Philippe, Montano, Nicola, Dyken, M E, Phillips, B G, and Somers, Virend Kristen

Abstract

Muscle sympathetic nerve activity (MSNA) is increased in patients with obstructive sleep apnea (OSA). We tested the hypothesis that tonic activation of excitatory chemoreceptor afferents contributes to the elevated sympathetic activity in OSA., Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S., info:eu-repo/semantics/published

Published
1998

7. Sympathetic activity in obese subjects with and without obstructive sleep apnea.

Author

Narkiewicz, K, Van De Borne, Philippe, Cooley, R L, Dyken, M E, Somers, Virend Kristen, Narkiewicz, K, Van De Borne, Philippe, Cooley, R L, Dyken, M E, and Somers, Virend Kristen

Abstract

Obese humans are reported to have increased muscle sympathetic nerve activity (MSNA). Obstructive sleep apnea (OSA) may also be accompanied by increased MSNA. Because there is a high prevalence of OSA in obese humans, it is possible that high MSNA reported in obese subjects may in fact reflect the presence of OSA in these subjects. We tested the hypothesis that obesity, per se, in the absence of OSA, is not accompanied by increased MSNA., Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S., info:eu-repo/semantics/published

Published
1998

8. Altered cardiovascular variability in obstructive sleep apnea.

Author

Narkiewicz, K, Montano, Nicola, Cogliati, C, Van De Borne, Philippe, Dyken, M E, Somers, Virend Kristen, Narkiewicz, K, Montano, Nicola, Cogliati, C, Van De Borne, Philippe, Dyken, M E, and Somers, Virend Kristen

Abstract

Altered cardiovascular variability is a prognostic indicator for cardiovascular events. Patients with obstructive sleep apnea (OSA) are at an increased risk for cardiovascular disease. We tested the hypothesis that OSA is accompanied by alterations in cardiovascular variability, even in the absence of overt cardiovascular disease., Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S., info:eu-repo/semantics/published

Published
1998

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