1. Upregulated Ubiquitin D is a Favorable Prognostic Indicator for Rectal Cancer Patients Undergoing Preoperative Concurrent Chemoradiotherapy
- Author
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Chou,Chia-Lin, Chen,Tzu-Ju, Li,Wan-Shan, Lee,Sung-Wei, Yang,Ching-Chieh, Tian,Yu-Feng, Lin,Cheng-Yi, He,Hong-Lin, Wu,Hung-Chang, Shiue,Yow-Ling, Li,Chien-Feng, Kuo,Yu-Hsuan, Chou,Chia-Lin, Chen,Tzu-Ju, Li,Wan-Shan, Lee,Sung-Wei, Yang,Ching-Chieh, Tian,Yu-Feng, Lin,Cheng-Yi, He,Hong-Lin, Wu,Hung-Chang, Shiue,Yow-Ling, Li,Chien-Feng, and Kuo,Yu-Hsuan
- Abstract
Chia-Lin Chou,1,2 Tzu-Ju Chen,1,3â 5 Wan-Shan Li,1,3,5 Sung-Wei Lee,6 Ching-Chieh Yang,7,8 Yu-Feng Tian,2 Cheng-Yi Lin,9 Hong-Lin He,10 Hung-Chang Wu,8,11 Yow-Ling Shiue,5,12 Chien-Feng Li,12â 14 Yu-Hsuan Kuo5,8,11,12 1Department of Medical Technology, Chung Hwa University of Medical Technology, Tainan, 717, Taiwan; 2Division of Colon and Rectal Surgery, Department of Surgery, Chi Mei Medical Center, Tainan, 710, Taiwan; 3Department of Pathology, Chi Mei Medical Center, Tainan, 710, Taiwan; 4Department of Clinical Pathology, Chi Mei Medical Center, Tainan, 710, Taiwan; 5Institute of Biomedical Science, National Sun Yat-Sen University, Kaohsiung, 804, Taiwan; 6Department of Radiation Oncology, Chi Mei Medical Center, Liouying, 736, Taiwan; 7Department of Radiation Oncology, Chi Mei Medical Center, Tainan, 710, Taiwan; 8College of Pharmacy and Science, Chia Nan University, Tainan, Taiwan; 9Division of Gastroenterology and Hepatology, Department of Internal Medicine, Chi Mei Medical Center, Tainan, 710, Taiwan; 10Department of Pathology, E-DA Hospital & E-DA Cancer Hospital, I-Shou University, Kaohsiung, 82445, Taiwan; 11Division of Hematology and Oncology, Department of Internal Medicine, Chi-Mei Medical Center, Tainan, Taiwan; 12Institute of Precision Medicine, National Sun Yat-Sen University, Kaohsiung, 804, Taiwan; 13Department of Medical Research, Chi Mei Medical Center, Tainan, 710, Taiwan; 14National Institute of Cancer Research, National Health Research Institutes, Miaoli County, 35053, TaiwanCorrespondence: Yu-Hsuan Kuo; Chien-Feng Li, No. 901, Zhonghua Road Yongkang Dist, Tainan City, Taiwan, Tel +886-6-2812811, Fax +886-6-2510218 ; Fax +886-6-2510218, Email beethovan@gmail.com; angelo.p@yahoo.com.twPurpose: For locally advanced rectal cancer, neoadjuvant concurrent chemoradiotherapy (CCRT) allows tumor downstaging and makes curative radical proctectomy possible. However, we lack a genetic biomarker to predict cancer prognosis or treatment response. W
- Published
- 2022