1. Acetylcholinesterase from Bungarus venom: a monomeric species.
- Author
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UCL, Cousin, X, Créminon, C, Grassi, J., Méflah, K, Cornu, Guy, Saliou, B, Bon, S, Massoulié, J, Bon, C, UCL, Cousin, X, Créminon, C, Grassi, J., Méflah, K, Cornu, Guy, Saliou, B, Bon, S, Massoulié, J, and Bon, C
- Abstract
The venom of Bungarus fasciatus, an Elapidae snake, contains a high level of AChE activity. Partial peptide sequences show that it is closely homologous to other AChEs. Bungarus venom AChE is a non-amphiphilic monomeric species, a molecular form of AChE which has not been previously found in significant levels in other tissues. The composition of carbohydrates suggests the presence of N-glycans of the 'complex' and 'hybrid' types. Ion exchange chromatography, isoelectric focusing and electrophoresis in non-denaturing and denaturing conditions reveal a complex microheterogeneity of this enzyme, which is partly related to its glycosylation.
- Published
- 1996