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Introduction: First of all, Tinospora cordifolia, sometimes referred to as “Amrita” or “Guduchi,” is a crucial  medication utilized in Indian Systems of Medicine and has been for ages. The Sanskrit term “guduchi” means “which  protects the body from diseases.” This herb is also known by the name “Amrita,” which in Hindu mythology alludes  to the celestial nectar. Aim: This well-known Indian bitter is recommended for fevers, diabetes, dyspepsia, jaundice, skin conditions,  kidney issues, persistent diarrhea, and dysentery. Leprosy, helminthiasis, rheumatoid arthritis, and cardiac problems  have all been shown to benefit from it. It is a significant medication that is utilized in a variety of preparations,  including Swarasa, Ghrita, Satva, Tail, etc. Material and Methods: For this review article, Charaka Samhita, Sushruta Samhita, Ashtanga Hridaya, Ashtanga  Sangraha, Bhavprakash Nighantu, Raj Nighantu, Dhanvantari Nighantu, Shaligrama Nighantu, Priya Nighantu, Kaiydev Nighantu, Madanpal Nighantu, Shodhal Nighantu. Results: It has long been recognized that the T. cordifolia plant possesses strong therapeutic, medicinal, healing, and  soothing properties. Discussion: Guduchi’s anti-toxic, anti-inflammatory, antipyretic, and anti-oxidant qualities make it a highly  promising medicinal herb. In addition, there is no proof that Guduchi contains any harmful substances or adverse  effects, demonstrating its safety. Conclusion: T. cordifolia, often known as Giloy, is an herb with medicinal characteristics that can prevent many  diseases or abnormalities by naturally boosting immunity in human bodies. These properties are confirmed by the  therapeutic and safety aspects research included in this review. Herbal and traditional medicines have a long history and are widely  used in India. Natural medicines are becoming more and more  important in clinical research these days. In

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