Search

Your search keyword '"Al-Seraihy A"' showing total 28 results
Start Over Author "Al-Seraihy A" Database OAIster
28 results on '"Al-Seraihy A"'

1. Outcomes of Unmanipulated Haploidentical Transplantation Using Post-Transplant Cyclophosphamide (PT-Cy) in Pediatric Patients With Acute Lymphoblastic Leukemia

Author

Ruggeri, A., Galimard, J. -E., Paina, O., Fagioli, F., Tbakhi, A., Yesilipek, A., Navarro, J. M. F., Faraci, M., Hamladji, R. -M., Skorobogatova, E., Al-Seraihy, A., Sundin, M., Herrera, C., Rifon, J., Dalissier, A., Locatelli, Franco, Rocha, V., Corbacioglu, S., Locatelli F. (ORCID:0000-0002-7976-3654), Ruggeri, A., Galimard, J. -E., Paina, O., Fagioli, F., Tbakhi, A., Yesilipek, A., Navarro, J. M. F., Faraci, M., Hamladji, R. -M., Skorobogatova, E., Al-Seraihy, A., Sundin, M., Herrera, C., Rifon, J., Dalissier, A., Locatelli, Franco, Rocha, V., Corbacioglu, S., and Locatelli F. (ORCID:0000-0002-7976-3654)

Abstract

HLA-haploidentical transplantation (haplo-HCT) using post-transplantation-cyclophosphamide (PT-Cy) is a feasible procedure in children with malignancies. However, large studies on Haplo-HCT with PT-Cy for childhood acute lymphoblastic leukemia (ALL) are lacking. We analyzed haplo-HCT outcomes in 180 children with ALL. Median age was 9 years, and median follow-up was 2.7 years. Disease status was CR1 for 24%, CR2 for 45%, CR+3 for 12%, and active disease for 19%. All patients received PT-Cy day +3 and +4. Bone marrow (BM) was the stem cell source in 115 patients (64%). Cumulative incidence of 42-day engraftment was 88.9%. Cumulative incidence of day-100 acute graft-versus-host disease (GVHD) grade II-IV was 28%, and 2-year chronic GVHD was 21.9%. At 2 years, cumulative incidence of nonrelapse mortality (NRM) was 19.6%. Cumulative incidence was 41.9% for relapse and 25% for patients in CR1. Estimated 2-year leukemia free survival was 65%, 44%, and 18.8% for patients transplanted in CR1, CR2, CR3+ and 3% at 1 year for active disease. In multivariable analysis for patients in CR1 and CR2, disease status (CR2 [hazard ratio {HR} = 2.19; P = .04]), age at HCT older than 13 (HR = 2.07; P = .03) and use of peripheral blood stem cell (PBSC) (HR = 1.98; P = .04) were independent factors associated with decreased overall survival. Use of PBSC was also associated with higher NRM (HR = 3.13; P = .04). Haplo-HCT with PT-Cy is an option for children with ALL, namely those transplanted in CR1 and CR2. Age and disease status remain the most important factors for outcomes. BM cells as a graft source is associated with improved survival.

Published
2021

2. Hematopoietic cell transplantation in chronic granulomatous disease: a study of 712 children and adults

Author

HEE, MS CGO, KTO Office, Utrecht Valorisatie Centrum, SCT patientenzorg, Child Health, Infection & Immunity, Regenerative Medicine and Stem Cells, Chiesa, Robert, Wang, Junfeng, Blok, Henric-Jan, Hazelaar, Sheree, Neven, Benedicte, Moshous, Despina, Schulz, Ansgar, Hoenig, Manfred, Hauck, Fabian, Al Seraihy, Amal, Gozdzik, Jolanta, Ljungman, Per, Lindemans, Caroline A, Fernandes, Juliana F, Kalwak, Krzysztof, Strahm, Brigitte, Schanz, Urs, Sedlacek, Petr, Sykora, Karl-Walter, Aksoylar, Serap, Locatelli, Franco, Stepensky, Polina, Wynn, Robert, Lum, Su Han, Zecca, Marco, Porta, Fulvio, Taskinen, Mervi, Gibson, Brenda, Matthes, Susanne, Karakukcu, Musa, Hauri-Hohl, Mathias, Veys, Paul, Gennery, Andrew R, Lucchini, Giovanna, Felber, Matthias, Albert, Michael H, Balashov, Dmitry, Lankester, Arjan, Güngör, Tayfun, Slatter, Mary A, HEE, MS CGO, KTO Office, Utrecht Valorisatie Centrum, SCT patientenzorg, Child Health, Infection & Immunity, Regenerative Medicine and Stem Cells, Chiesa, Robert, Wang, Junfeng, Blok, Henric-Jan, Hazelaar, Sheree, Neven, Benedicte, Moshous, Despina, Schulz, Ansgar, Hoenig, Manfred, Hauck, Fabian, Al Seraihy, Amal, Gozdzik, Jolanta, Ljungman, Per, Lindemans, Caroline A, Fernandes, Juliana F, Kalwak, Krzysztof, Strahm, Brigitte, Schanz, Urs, Sedlacek, Petr, Sykora, Karl-Walter, Aksoylar, Serap, Locatelli, Franco, Stepensky, Polina, Wynn, Robert, Lum, Su Han, Zecca, Marco, Porta, Fulvio, Taskinen, Mervi, Gibson, Brenda, Matthes, Susanne, Karakukcu, Musa, Hauri-Hohl, Mathias, Veys, Paul, Gennery, Andrew R, Lucchini, Giovanna, Felber, Matthias, Albert, Michael H, Balashov, Dmitry, Lankester, Arjan, Güngör, Tayfun, and Slatter, Mary A

Published
2020

3. Risk factors and outcomes according to age at transplantation with an HLA-identical sibling for sickle cell disease

Author

Cappelli, B., Volt, F., Tozatto-Maio, K., Scigliuolo, G. M., Ferster, A., Dupont, S., Simoes, B. P., Al-Seraihy, A., Aljurf, M. D., Almohareb, F., Belendez, C., Matthes, S., Dhedin, N., Pondarre, C., Dalle, J. -H., Bertrand, Y., Vannier, J. P., Kuentz, M., Lutz, P., Michel, G., Rafii, H., Neven, B., Zecca, M., Bader, P., Cavazzana, M., Labopin, M., Locatelli, Franco, Magnani, A., Ruggeri, A., Rocha, V., Bernaudin, F., de la Fuente, J., Corbacioglu, S., Gluckman, E., Locatelli F. (ORCID:0000-0002-7976-3654), Cappelli, B., Volt, F., Tozatto-Maio, K., Scigliuolo, G. M., Ferster, A., Dupont, S., Simoes, B. P., Al-Seraihy, A., Aljurf, M. D., Almohareb, F., Belendez, C., Matthes, S., Dhedin, N., Pondarre, C., Dalle, J. -H., Bertrand, Y., Vannier, J. P., Kuentz, M., Lutz, P., Michel, G., Rafii, H., Neven, B., Zecca, M., Bader, P., Cavazzana, M., Labopin, M., Locatelli, Franco, Magnani, A., Ruggeri, A., Rocha, V., Bernaudin, F., de la Fuente, J., Corbacioglu, S., Gluckman, E., and Locatelli F. (ORCID:0000-0002-7976-3654)

Abstract

NO ABSTRACT

Published
2019

4. Risk factors and outcomes according to age at transplantation with an HLA-identical sibling for sickle cell disease

Author

Cappelli, Barbara, Volt, Fernanda, Tozatto-Maio, Karina, Scigliuolo, Graziana Maria, Ferster, Alina, Dupont, Sophie, Simões, Belinda Pinto, Al-Seraihy, Amal, Aljurf, Mahmoud, Almohareb, Fahad, Belendez, Cristina, Matthes, Susanne, Dhedin, Nathalie, Pondarre, Corinne, Dalle, Jean Hugues, Bertrand, Yves, Vannier, Jean Pierre, Kuentz, Mathieu, Lutz, Patrick, Michel, Gérard, Rafii, Hanadi, Neven, Bénédicte, Zecca, Marco, Bader, Peter, Cavazzana, Marina, Labopin, Myriam, Locatelli, Franco, Magnani, Alessandra, Ruggeri, A., Rocha, Vanderson Geraldo, Bernaudin, Françoise, de la Fuente, Josu, Corbacioglu, Selim, Gluckman, Éliane E., Cappelli, Barbara, Volt, Fernanda, Tozatto-Maio, Karina, Scigliuolo, Graziana Maria, Ferster, Alina, Dupont, Sophie, Simões, Belinda Pinto, Al-Seraihy, Amal, Aljurf, Mahmoud, Almohareb, Fahad, Belendez, Cristina, Matthes, Susanne, Dhedin, Nathalie, Pondarre, Corinne, Dalle, Jean Hugues, Bertrand, Yves, Vannier, Jean Pierre, Kuentz, Mathieu, Lutz, Patrick, Michel, Gérard, Rafii, Hanadi, Neven, Bénédicte, Zecca, Marco, Bader, Peter, Cavazzana, Marina, Labopin, Myriam, Locatelli, Franco, Magnani, Alessandra, Ruggeri, A., Rocha, Vanderson Geraldo, Bernaudin, Françoise, de la Fuente, Josu, Corbacioglu, Selim, and Gluckman, Éliane E.

Abstract

SCOPUS: le.j, info:eu-repo/semantics/published

Published
2019

5. Early and late outcomes after cord blood transplantation for pediatric patients with inherited leukodystrophies

Author

Van Den Broek, Brigitte A., Page, Kristin, Paviglianiti, Annalisa, Hol, Janna, Allewelt, Heather, Volt, Fernanda, Michel, Gerard, Diaz, Miguel Angel, Bordon, Victoria, O'Brien, Tracey, Shaw, Peter J., Kenzey, Chantal, Al-Seraihy, Amal, Van Hasselt, Peter M., Gennery, Andrew R., Gluckman, Eliane, Rocha, Vanderson, Ruggeri, Annalisa, Kurtzberg, Joanne, Boelens, Jaap Jan, Van Den Broek, Brigitte A., Page, Kristin, Paviglianiti, Annalisa, Hol, Janna, Allewelt, Heather, Volt, Fernanda, Michel, Gerard, Diaz, Miguel Angel, Bordon, Victoria, O'Brien, Tracey, Shaw, Peter J., Kenzey, Chantal, Al-Seraihy, Amal, Van Hasselt, Peter M., Gennery, Andrew R., Gluckman, Eliane, Rocha, Vanderson, Ruggeri, Annalisa, Kurtzberg, Joanne, and Boelens, Jaap Jan

Published
2018

6. Early and late outcomes after cord blood transplantation for pediatric patients with inherited leukodystrophies

Author

Van Den Broek, Brigitte A., Page, Kristin, Paviglianiti, Annalisa, Hol, Janna, Allewelt, Heather, Volt, Fernanda, Michel, Gerard, Diaz, Miguel Angel, Bordon, Victoria, O'Brien, Tracey, Shaw, Peter J., Kenzey, Chantal, Al-Seraihy, Amal, Van Hasselt, Peter M., Gennery, Andrew R., Gluckman, Eliane, Rocha, Vanderson, Ruggeri, Annalisa, Kurtzberg, Joanne, Boelens, Jaap Jan, Van Den Broek, Brigitte A., Page, Kristin, Paviglianiti, Annalisa, Hol, Janna, Allewelt, Heather, Volt, Fernanda, Michel, Gerard, Diaz, Miguel Angel, Bordon, Victoria, O'Brien, Tracey, Shaw, Peter J., Kenzey, Chantal, Al-Seraihy, Amal, Van Hasselt, Peter M., Gennery, Andrew R., Gluckman, Eliane, Rocha, Vanderson, Ruggeri, Annalisa, Kurtzberg, Joanne, and Boelens, Jaap Jan

Published
2018

7. Early and late outcomes after cord blood transplantation for pediatric patients with inherited leukodystrophies

Author

UMC Utrecht, CTI Management, SCT onderzoek, Genetica Klinische Genetica, Cluster C, Metabole ziekten patientenzorg, Child Health, Regenerative Medicine and Stem Cells, CTI Nierkens, Infection & Immunity, Van Den Broek, Brigitte A., Page, Kristin, Paviglianiti, Annalisa, Hol, Janna, Allewelt, Heather, Volt, Fernanda, Michel, Gerard, Diaz, Miguel Angel, Bordon, Victoria, O'Brien, Tracey, Shaw, Peter J., Kenzey, Chantal, Al-Seraihy, Amal, Van Hasselt, Peter M., Gennery, Andrew R., Gluckman, Eliane, Rocha, Vanderson, Ruggeri, Annalisa, Kurtzberg, Joanne, Boelens, Jaap Jan, UMC Utrecht, CTI Management, SCT onderzoek, Genetica Klinische Genetica, Cluster C, Metabole ziekten patientenzorg, Child Health, Regenerative Medicine and Stem Cells, CTI Nierkens, Infection & Immunity, Van Den Broek, Brigitte A., Page, Kristin, Paviglianiti, Annalisa, Hol, Janna, Allewelt, Heather, Volt, Fernanda, Michel, Gerard, Diaz, Miguel Angel, Bordon, Victoria, O'Brien, Tracey, Shaw, Peter J., Kenzey, Chantal, Al-Seraihy, Amal, Van Hasselt, Peter M., Gennery, Andrew R., Gluckman, Eliane, Rocha, Vanderson, Ruggeri, Annalisa, Kurtzberg, Joanne, and Boelens, Jaap Jan

Published
2018

8. An integrative scoring system for survival prediction following umbilical cord blood transplantation in acute leukemia

Author

Shouval, Roni, Ruggeri, Annalisa, Labopin, Myriam, Mohty, Mohamad, Sanz, Guillermo, Michel, Gerard, Kuball, Jürgen, Chevallier, Patrice, Al-Seraihy, Amal, Milpied, Noel Jean, De Heredia, Cristina Diaz, Arcese, William, Blaise, Didier, Rocha, Vanderson, Fein, Joshua, Unger, Ron, Baron, Frederic, Bader, Peter, Gluckman, Eliane, Nagler, Arnon, Shouval, Roni, Ruggeri, Annalisa, Labopin, Myriam, Mohty, Mohamad, Sanz, Guillermo, Michel, Gerard, Kuball, Jürgen, Chevallier, Patrice, Al-Seraihy, Amal, Milpied, Noel Jean, De Heredia, Cristina Diaz, Arcese, William, Blaise, Didier, Rocha, Vanderson, Fein, Joshua, Unger, Ron, Baron, Frederic, Bader, Peter, Gluckman, Eliane, and Nagler, Arnon

Published
2017

9. An integrative scoring system for survival prediction following umbilical cord blood transplantation in acute leukemia

Author

Shouval, Roni, Ruggeri, Annalisa, Labopin, Myriam, Mohty, Mohamad, Sanz, Guillermo, Michel, Gerard, Kuball, Jürgen, Chevallier, Patrice, Al-Seraihy, Amal, Milpied, Noel Jean, De Heredia, Cristina Diaz, Arcese, William, Blaise, Didier, Rocha, Vanderson, Fein, Joshua, Unger, Ron, Baron, Frederic, Bader, Peter, Gluckman, Eliane, Nagler, Arnon, Shouval, Roni, Ruggeri, Annalisa, Labopin, Myriam, Mohty, Mohamad, Sanz, Guillermo, Michel, Gerard, Kuball, Jürgen, Chevallier, Patrice, Al-Seraihy, Amal, Milpied, Noel Jean, De Heredia, Cristina Diaz, Arcese, William, Blaise, Didier, Rocha, Vanderson, Fein, Joshua, Unger, Ron, Baron, Frederic, Bader, Peter, Gluckman, Eliane, and Nagler, Arnon

Published
2017

10. An integrative scoring system for survival prediction following umbilical cord blood transplantation in acute leukemia

Author

Shouval, Roni, Ruggeri, Annalisa, Labopin, Myriam, Mohty, Mohamad, Sanz, Guillermo, Michel, Gerard, Kuball, Jürgen, Chevallier, Patrice, Al-Seraihy, Amal, Milpied, Noel Jean, De Heredia, Cristina Diaz, Arcese, William, Blaise, Didier, Rocha, Vanderson, Fein, Joshua, Unger, Ron, Baron, Frederic, Bader, Peter, Gluckman, Eliane, Nagler, Arnon, Shouval, Roni, Ruggeri, Annalisa, Labopin, Myriam, Mohty, Mohamad, Sanz, Guillermo, Michel, Gerard, Kuball, Jürgen, Chevallier, Patrice, Al-Seraihy, Amal, Milpied, Noel Jean, De Heredia, Cristina Diaz, Arcese, William, Blaise, Didier, Rocha, Vanderson, Fein, Joshua, Unger, Ron, Baron, Frederic, Bader, Peter, Gluckman, Eliane, and Nagler, Arnon

Published
2017

11. An integrative scoring system for survival prediction following umbilical cord blood transplantation in acute leukemia

Author

UMC Utrecht, CTI Kuball, MS Hematologie, Cancer, Regenerative Medicine and Stem Cells, Infection & Immunity, Shouval, Roni, Ruggeri, Annalisa, Labopin, Myriam, Mohty, Mohamad, Sanz, Guillermo, Michel, Gerard, Kuball, Jürgen, Chevallier, Patrice, Al-Seraihy, Amal, Milpied, Noel Jean, De Heredia, Cristina Diaz, Arcese, William, Blaise, Didier, Rocha, Vanderson, Fein, Joshua, Unger, Ron, Baron, Frederic, Bader, Peter, Gluckman, Eliane, Nagler, Arnon, UMC Utrecht, CTI Kuball, MS Hematologie, Cancer, Regenerative Medicine and Stem Cells, Infection & Immunity, Shouval, Roni, Ruggeri, Annalisa, Labopin, Myriam, Mohty, Mohamad, Sanz, Guillermo, Michel, Gerard, Kuball, Jürgen, Chevallier, Patrice, Al-Seraihy, Amal, Milpied, Noel Jean, De Heredia, Cristina Diaz, Arcese, William, Blaise, Didier, Rocha, Vanderson, Fein, Joshua, Unger, Ron, Baron, Frederic, Bader, Peter, Gluckman, Eliane, and Nagler, Arnon

Published
2017

12. Incidence and severity of crucial late effects after allogeneic HSCT for malignancy under the age of 3 years : TBI is what really matters

Author

Bresters, D, Lawitschka, A, Cugno, C, Pötschger, U, Dalissier, A, Michel, G, Vettenranta, K, Sundin, M, Al-Seraihy, A, Faraci, M, Sedlacek, P, Versluys, A B, Jenkins, A, Lutz, P, Gibson, B, Leiper, A, Diaz, M A, Shaw, P J, Skinner, R, O'Brien, T A, Salooja, N, Bader, P, Peters, C, Bresters, D, Lawitschka, A, Cugno, C, Pötschger, U, Dalissier, A, Michel, G, Vettenranta, K, Sundin, M, Al-Seraihy, A, Faraci, M, Sedlacek, P, Versluys, A B, Jenkins, A, Lutz, P, Gibson, B, Leiper, A, Diaz, M A, Shaw, P J, Skinner, R, O'Brien, T A, Salooja, N, Bader, P, and Peters, C

Published
2016

13. Outcomes after Unrelated Umbilical Cord Blood Transplantation for Children with Osteopetrosis.

Author

UCL - SSS/IREC/PEDI - Pôle de Pédiatrie, UCL - (SLuc) Service d'hématologie et d'oncologie pédiatrique, Chiesa, Robert, Ruggeri, Annalisa, Paviglianiti, Annalisa, Zecca, Marco, Gónzalez-Vicent, Marta, Bordon, Victoria, Stein, Jerry, Lawson, Sarah, Dupont, Sophie, Lanino, Edoardo, Abecasis, Manuel, Al-Seraihy, Amal, Kenzey, Chantal, Bierings, Marc, Locatelli, Franco, Gluckman, Eliane, Schulz, Ansgar, Gennery, Andrew, Page, Kristin, Kurtzberg, Joanne, Rocha, Vanderson, European Group for Blood and Marrow Transplantation, UCL - SSS/IREC/PEDI - Pôle de Pédiatrie, UCL - (SLuc) Service d'hématologie et d'oncologie pédiatrique, Chiesa, Robert, Ruggeri, Annalisa, Paviglianiti, Annalisa, Zecca, Marco, Gónzalez-Vicent, Marta, Bordon, Victoria, Stein, Jerry, Lawson, Sarah, Dupont, Sophie, Lanino, Edoardo, Abecasis, Manuel, Al-Seraihy, Amal, Kenzey, Chantal, Bierings, Marc, Locatelli, Franco, Gluckman, Eliane, Schulz, Ansgar, Gennery, Andrew, Page, Kristin, Kurtzberg, Joanne, Rocha, Vanderson, and European Group for Blood and Marrow Transplantation

Abstract

Hematopoietic stem cell transplantation (HSCT) is the only curative treatment for most children with osteopetrosis (OP). Timing of HSCT is critical; therefore, umbilical cord blood transplantation (UCBT) is an attractive option. We analyzed outcomes after UCBT in 51 OP children. Median age at UCBT was 6 months. Seventy-seven percent of the cord blood grafts had 0 or 1 HLA disparity with the recipient. Conditioning regimen was myeloablative (mostly busulfan-based in 84% and treosulfan-based in 10%). Antithymocyte globulin was given to 90% of patients. Median number of total nucleated and CD34 cells infused was 14 × 10/kg and 3.4 × 10/kg, respectively. Median follow-up for survivors was 74 months. Cumulative incidence (CI) of neutrophil recovery was 67% with a median time to recovery of 23 days; 33% of patients had graft failure, 81% of engrafted patients had full donor engraftment, and 19% had mixed donor chimerism. Day 100 CI of acute graft-versus-host disease (grades II to IV) was 31% and 6-year CI of chronic graft-versus-host disease was 21%. Mechanical ventilation was required in 28%, and veno-occlusive disease was diagnosed in 16% of cases. Six-year overall survival rate was 46%. Comparative studies with other alternative donors should be performed to evaluate whether UCBT remains a valid alternative for children with OP without an HLA-matched donor.

Published
2016

14. Incidence and severity of crucial late effects after allogeneic HSCT for malignancy under the age of 3 years : TBI is what really matters

Author

Bresters, D, Lawitschka, A, Cugno, C, Pötschger, U, Dalissier, A, Michel, G, Vettenranta, K, Sundin, M, Al-Seraihy, A, Faraci, M, Sedlacek, P, Versluys, A B, Jenkins, A, Lutz, P, Gibson, B, Leiper, A, Diaz, M A, Shaw, P J, Skinner, R, O'Brien, T A, Salooja, N, Bader, P, Peters, C, Bresters, D, Lawitschka, A, Cugno, C, Pötschger, U, Dalissier, A, Michel, G, Vettenranta, K, Sundin, M, Al-Seraihy, A, Faraci, M, Sedlacek, P, Versluys, A B, Jenkins, A, Lutz, P, Gibson, B, Leiper, A, Diaz, M A, Shaw, P J, Skinner, R, O'Brien, T A, Salooja, N, Bader, P, and Peters, C

Published
2016

15. Outcomes after Unrelated Umbilical Cord Blood Transplantation for Children with Osteopetrosis

Author

Chiesa, Robert, Ruggeri, Annalisa, Paviglianiti, Annalisa, Zecca, Marco, Gónzalez-Vicent, Marta, Bordon, Victoria, Stein, Jerry, Lawson, Sarah, Dupont, Sophie, Lanino, Edoardo, Abecasis, Manuel, Al-Seraihy, Amal, Kenzey, Chantal, Bierings, Marc, Locatelli, Franco, Gluckman, Eliane, Schulz, Ansgar, Gennery, Andrew, Page, Kristin, Kurtzberg, Joanne, Rocha, Vanderson, Chiesa, Robert, Ruggeri, Annalisa, Paviglianiti, Annalisa, Zecca, Marco, Gónzalez-Vicent, Marta, Bordon, Victoria, Stein, Jerry, Lawson, Sarah, Dupont, Sophie, Lanino, Edoardo, Abecasis, Manuel, Al-Seraihy, Amal, Kenzey, Chantal, Bierings, Marc, Locatelli, Franco, Gluckman, Eliane, Schulz, Ansgar, Gennery, Andrew, Page, Kristin, Kurtzberg, Joanne, and Rocha, Vanderson

Published
2016

16. Incidence and severity of crucial late effects after allogeneic HSCT for malignancy under the age of 3 years : TBI is what really matters

Author

Bresters, D, Lawitschka, A, Cugno, C, Pötschger, U, Dalissier, A, Michel, G, Vettenranta, K, Sundin, M, Al-Seraihy, A, Faraci, M, Sedlacek, P, Versluys, A B, Jenkins, A, Lutz, P, Gibson, B, Leiper, A, Diaz, M A, Shaw, P J, Skinner, R, O'Brien, T A, Salooja, N, Bader, P, Peters, C, Bresters, D, Lawitschka, A, Cugno, C, Pötschger, U, Dalissier, A, Michel, G, Vettenranta, K, Sundin, M, Al-Seraihy, A, Faraci, M, Sedlacek, P, Versluys, A B, Jenkins, A, Lutz, P, Gibson, B, Leiper, A, Diaz, M A, Shaw, P J, Skinner, R, O'Brien, T A, Salooja, N, Bader, P, and Peters, C

Published
2016

17. Outcomes after Unrelated Umbilical Cord Blood Transplantation for Children with Osteopetrosis

Author

Chiesa, Robert, Ruggeri, Annalisa, Paviglianiti, Annalisa, Zecca, Marco, Gónzalez-Vicent, Marta, Bordon, Victoria, Stein, Jerry, Lawson, Sarah, Dupont, Sophie, Lanino, Edoardo, Abecasis, Manuel, Al-Seraihy, Amal, Kenzey, Chantal, Bierings, Marc, Locatelli, Franco, Gluckman, Eliane, Schulz, Ansgar, Gennery, Andrew, Page, Kristin, Kurtzberg, Joanne, Rocha, Vanderson, Chiesa, Robert, Ruggeri, Annalisa, Paviglianiti, Annalisa, Zecca, Marco, Gónzalez-Vicent, Marta, Bordon, Victoria, Stein, Jerry, Lawson, Sarah, Dupont, Sophie, Lanino, Edoardo, Abecasis, Manuel, Al-Seraihy, Amal, Kenzey, Chantal, Bierings, Marc, Locatelli, Franco, Gluckman, Eliane, Schulz, Ansgar, Gennery, Andrew, Page, Kristin, Kurtzberg, Joanne, and Rocha, Vanderson

Published
2016

18. Incidence and severity of crucial late effects after allogeneic HSCT for malignancy under the age of 3 years: TBI is what really matters

Author

Haematologie patientenzorg, Child Health, Bresters, D, Lawitschka, A, Cugno, C, Pötschger, U, Dalissier, A, Michel, G, Vettenranta, K, Sundin, M, Al-Seraihy, A, Faraci, M, Sedlacek, P, Versluys, A B, Jenkins, A, Lutz, P, Gibson, B, Leiper, A, Diaz, M A, Shaw, P J, Skinner, R, O'Brien, T A, Salooja, N, Bader, P, Peters, C, Haematologie patientenzorg, Child Health, Bresters, D, Lawitschka, A, Cugno, C, Pötschger, U, Dalissier, A, Michel, G, Vettenranta, K, Sundin, M, Al-Seraihy, A, Faraci, M, Sedlacek, P, Versluys, A B, Jenkins, A, Lutz, P, Gibson, B, Leiper, A, Diaz, M A, Shaw, P J, Skinner, R, O'Brien, T A, Salooja, N, Bader, P, and Peters, C

Published
2016

19. Outcomes after Unrelated Umbilical Cord Blood Transplantation for Children with Osteopetrosis

Author

Haematologie, Child Health, Regenerative Medicine and Stem Cells, Chiesa, Robert, Ruggeri, Annalisa, Paviglianiti, Annalisa, Zecca, Marco, Gónzalez-Vicent, Marta, Bordon, Victoria, Stein, Jerry, Lawson, Sarah, Dupont, Sophie, Lanino, Edoardo, Abecasis, Manuel, Al-Seraihy, Amal, Kenzey, Chantal, Bierings, Marc, Locatelli, Franco, Gluckman, Eliane, Schulz, Ansgar, Gennery, Andrew, Page, Kristin, Kurtzberg, Joanne, Rocha, Vanderson, Haematologie, Child Health, Regenerative Medicine and Stem Cells, Chiesa, Robert, Ruggeri, Annalisa, Paviglianiti, Annalisa, Zecca, Marco, Gónzalez-Vicent, Marta, Bordon, Victoria, Stein, Jerry, Lawson, Sarah, Dupont, Sophie, Lanino, Edoardo, Abecasis, Manuel, Al-Seraihy, Amal, Kenzey, Chantal, Bierings, Marc, Locatelli, Franco, Gluckman, Eliane, Schulz, Ansgar, Gennery, Andrew, Page, Kristin, Kurtzberg, Joanne, and Rocha, Vanderson

Published
2016

20. Outcomes after Unrelated Umbilical Cord Blood Transplantation for Children with Osteopetrosis

Author

Chiesa, R., Ruggeri, A., Paviglianiti, A., Zecca, M., Gonzalez-Vicent, M., Bordon, V., Stein, J., Lawson, S., Dupont, S., Lanino, E., Abecasis, M., Al-Seraihy, A., Kenzey, C., Bierings, M., Locatelli, Franco, Gluckman, E., Schulz, A., Gennery, A., Page, K., Kurtzberg, J., Rocha, V., Locatelli F. (ORCID:0000-0002-7976-3654), Chiesa, R., Ruggeri, A., Paviglianiti, A., Zecca, M., Gonzalez-Vicent, M., Bordon, V., Stein, J., Lawson, S., Dupont, S., Lanino, E., Abecasis, M., Al-Seraihy, A., Kenzey, C., Bierings, M., Locatelli, Franco, Gluckman, E., Schulz, A., Gennery, A., Page, K., Kurtzberg, J., Rocha, V., and Locatelli F. (ORCID:0000-0002-7976-3654)

Abstract

Hematopoietic stem cell transplantation (HSCT) is the only curative treatment for most children with osteopetrosis (OP). Timing of HSCT is critical; therefore, umbilical cord blood transplantation (UCBT) is an attractive option. We analyzed outcomes after UCBT in 51 OP children. Median age at UCBT was 6 months. Seventy-seven percent of the cord blood grafts had 0 or 1 HLA disparity with the recipient. Conditioning regimen was myeloablative (mostly busulfan-based in 84% and treosulfan-based in 10%). Antithymocyte globulin was given to 90% of patients. Median number of total nucleated and CD34+ cells infused was 14 × 107/kg and 3.4 × 105/kg, respectively. Median follow-up for survivors was 74 months. Cumulative incidence (CI) of neutrophil recovery was 67% with a median time to recovery of 23 days; 33% of patients had graft failure, 81% of engrafted patients had full donor engraftment, and 19% had mixed donor chimerism. Day 100 CI of acute graft-versus-host disease (grades II to IV) was 31% and 6-year CI of chronic graft-versus-host disease was 21%. Mechanical ventilation was required in 28%, and veno-occlusive disease was diagnosed in 16% of cases. Six-year overall survival rate was 46%. Comparative studies with other alternative donors should be performed to evaluate whether UCBT remains a valid alternative for children with OP without an HLA-matched donor.

Published
2016

21. Hematopoietic stem cell transplantation for infantile osteopetrosis

Author

Orchard, Paul J., Fasth, Anders L., Le Rademacher, Jennifer L., He, Wensheng, Boelens, Jaap Jan, Horwitz, Edwin M., Al-Seraihy, Amal, Ayas, Mouhab, Bonfim, Carmem M., Boulad, Farid, Lund, Troy, Buchbinder, David K., Kapoor, Neena, OBrien, Tracey A., Perez, Miguel A Diaz, Veys, Paul A., Eapen, Mary, Orchard, Paul J., Fasth, Anders L., Le Rademacher, Jennifer L., He, Wensheng, Boelens, Jaap Jan, Horwitz, Edwin M., Al-Seraihy, Amal, Ayas, Mouhab, Bonfim, Carmem M., Boulad, Farid, Lund, Troy, Buchbinder, David K., Kapoor, Neena, OBrien, Tracey A., Perez, Miguel A Diaz, Veys, Paul A., and Eapen, Mary

Published
2015

22. Stem cell transplantation in severe congenital neutropenia : an analysis from the European Society for Blood and Marrow Transplantation

Author

Fioredda, Francesca, Iacobelli, Simona, van Biezen, Anja, Gaspar, Bobby, Ancliff, Phil, Donadieu, Jean, Aljurf, Mahmoud, Peters, Christina, Calvillo, Michaela, Matthes-Martin, Susanne, Morreale, Giuseppe, van 't Veer-Tazelaar, Nelleke, de Wreede, Liesbeth, Al Seraihy, Amal, Yesilipek, Akif, Fischer, Alain, Bierings, Marc, Ozturk, Gulyuz, Smith, Owen, Veys, Paul, Ljungman, Per, Peffault de Latour, Régis, Sánchez de Toledo Codina, José, Or, Reuven, Ganser, Arnold, Afanasyev, Boris, Wynn, Robert, Kalwak, Krzysztof, Marsh, Judith, Dufour, Carlo, Severe Aplastic Anemia the Inborn Error, and the Pediatric Disease Working Parties of the European Society for Blood and Bone Marrow Transplantation (EBMT) and Stem Cell Transplant for Immunodeficiencies in Europe (SCETIDE), Fioredda, Francesca, Iacobelli, Simona, van Biezen, Anja, Gaspar, Bobby, Ancliff, Phil, Donadieu, Jean, Aljurf, Mahmoud, Peters, Christina, Calvillo, Michaela, Matthes-Martin, Susanne, Morreale, Giuseppe, van 't Veer-Tazelaar, Nelleke, de Wreede, Liesbeth, Al Seraihy, Amal, Yesilipek, Akif, Fischer, Alain, Bierings, Marc, Ozturk, Gulyuz, Smith, Owen, Veys, Paul, Ljungman, Per, Peffault de Latour, Régis, Sánchez de Toledo Codina, José, Or, Reuven, Ganser, Arnold, Afanasyev, Boris, Wynn, Robert, Kalwak, Krzysztof, Marsh, Judith, Dufour, Carlo, and Severe Aplastic Anemia the Inborn Error, and the Pediatric Disease Working Parties of the European Society for Blood and Bone Marrow Transplantation (EBMT) and Stem Cell Transplant for Immunodeficiencies in Europe (SCETIDE)

Published
2015

23. Stem cell transplantation in severe congenital neutropenia : an analysis from the European Society for Blood and Marrow Transplantation

Author

Fioredda, Francesca, Iacobelli, Simona, van Biezen, Anja, Gaspar, Bobby, Ancliff, Phil, Donadieu, Jean, Aljurf, Mahmoud, Peters, Christina, Calvillo, Michaela, Matthes-Martin, Susanne, Morreale, Giuseppe, van 't Veer-Tazelaar, Nelleke, de Wreede, Liesbeth, Al Seraihy, Amal, Yesilipek, Akif, Fischer, Alain, Bierings, Marc, Ozturk, Gulyuz, Smith, Owen, Veys, Paul, Ljungman, Per, Peffault de Latour, Régis, Sánchez de Toledo Codina, José, Or, Reuven, Ganser, Arnold, Afanasyev, Boris, Wynn, Robert, Kalwak, Krzysztof, Marsh, Judith, Dufour, Carlo, Severe Aplastic Anemia the Inborn Error, and the Pediatric Disease Working Parties of the European Society for Blood and Bone Marrow Transplantation (EBMT) and Stem Cell Transplant for Immunodeficiencies in Europe (SCETIDE), Fioredda, Francesca, Iacobelli, Simona, van Biezen, Anja, Gaspar, Bobby, Ancliff, Phil, Donadieu, Jean, Aljurf, Mahmoud, Peters, Christina, Calvillo, Michaela, Matthes-Martin, Susanne, Morreale, Giuseppe, van 't Veer-Tazelaar, Nelleke, de Wreede, Liesbeth, Al Seraihy, Amal, Yesilipek, Akif, Fischer, Alain, Bierings, Marc, Ozturk, Gulyuz, Smith, Owen, Veys, Paul, Ljungman, Per, Peffault de Latour, Régis, Sánchez de Toledo Codina, José, Or, Reuven, Ganser, Arnold, Afanasyev, Boris, Wynn, Robert, Kalwak, Krzysztof, Marsh, Judith, Dufour, Carlo, and Severe Aplastic Anemia the Inborn Error, and the Pediatric Disease Working Parties of the European Society for Blood and Bone Marrow Transplantation (EBMT) and Stem Cell Transplant for Immunodeficiencies in Europe (SCETIDE)

Published
2015

24. Hematopoietic stem cell transplantation for infantile osteopetrosis

Author

Orchard, Paul J., Fasth, Anders L., Le Rademacher, Jennifer L., He, Wensheng, Boelens, Jaap Jan, Horwitz, Edwin M., Al-Seraihy, Amal, Ayas, Mouhab, Bonfim, Carmem M., Boulad, Farid, Lund, Troy, Buchbinder, David K., Kapoor, Neena, OBrien, Tracey A., Perez, Miguel A Diaz, Veys, Paul A., Eapen, Mary, Orchard, Paul J., Fasth, Anders L., Le Rademacher, Jennifer L., He, Wensheng, Boelens, Jaap Jan, Horwitz, Edwin M., Al-Seraihy, Amal, Ayas, Mouhab, Bonfim, Carmem M., Boulad, Farid, Lund, Troy, Buchbinder, David K., Kapoor, Neena, OBrien, Tracey A., Perez, Miguel A Diaz, Veys, Paul A., and Eapen, Mary

Published
2015

25. Hematopoietic stem cell transplantation for infantile osteopetrosis

Author

Orchard, Paul J., Fasth, Anders L., Le Rademacher, Jennifer L., He, Wensheng, Boelens, Jaap Jan, Horwitz, Edwin M., Al-Seraihy, Amal, Ayas, Mouhab, Bonfim, Carmem M., Boulad, Farid, Lund, Troy, Buchbinder, David K., Kapoor, Neena, OBrien, Tracey A., Perez, Miguel A Diaz, Veys, Paul A., Eapen, Mary, Orchard, Paul J., Fasth, Anders L., Le Rademacher, Jennifer L., He, Wensheng, Boelens, Jaap Jan, Horwitz, Edwin M., Al-Seraihy, Amal, Ayas, Mouhab, Bonfim, Carmem M., Boulad, Farid, Lund, Troy, Buchbinder, David K., Kapoor, Neena, OBrien, Tracey A., Perez, Miguel A Diaz, Veys, Paul A., and Eapen, Mary

Published
2015

26. Stem cell transplantation in severe congenital neutropenia : an analysis from the European Society for Blood and Marrow Transplantation

Author

Fioredda, Francesca, Iacobelli, Simona, van Biezen, Anja, Gaspar, Bobby, Ancliff, Phil, Donadieu, Jean, Aljurf, Mahmoud, Peters, Christina, Calvillo, Michaela, Matthes-Martin, Susanne, Morreale, Giuseppe, van 't Veer-Tazelaar, Nelleke, de Wreede, Liesbeth, Al Seraihy, Amal, Yesilipek, Akif, Fischer, Alain, Bierings, Marc, Ozturk, Gulyuz, Smith, Owen, Veys, Paul, Ljungman, Per, Peffault de Latour, Régis, Sánchez de Toledo Codina, José, Or, Reuven, Ganser, Arnold, Afanasyev, Boris, Wynn, Robert, Kalwak, Krzysztof, Marsh, Judith, Dufour, Carlo, Severe Aplastic Anemia the Inborn Error, and the Pediatric Disease Working Parties of the European Society for Blood and Bone Marrow Transplantation (EBMT) and Stem Cell Transplant for Immunodeficiencies in Europe (SCETIDE), Fioredda, Francesca, Iacobelli, Simona, van Biezen, Anja, Gaspar, Bobby, Ancliff, Phil, Donadieu, Jean, Aljurf, Mahmoud, Peters, Christina, Calvillo, Michaela, Matthes-Martin, Susanne, Morreale, Giuseppe, van 't Veer-Tazelaar, Nelleke, de Wreede, Liesbeth, Al Seraihy, Amal, Yesilipek, Akif, Fischer, Alain, Bierings, Marc, Ozturk, Gulyuz, Smith, Owen, Veys, Paul, Ljungman, Per, Peffault de Latour, Régis, Sánchez de Toledo Codina, José, Or, Reuven, Ganser, Arnold, Afanasyev, Boris, Wynn, Robert, Kalwak, Krzysztof, Marsh, Judith, Dufour, Carlo, and Severe Aplastic Anemia the Inborn Error, and the Pediatric Disease Working Parties of the European Society for Blood and Bone Marrow Transplantation (EBMT) and Stem Cell Transplant for Immunodeficiencies in Europe (SCETIDE)

Published
2015

27. Stem cell transplantation in severe congenital neutropenia: an analysis from the European Society for Blood and Marrow Transplantation

Author

Haematologie, Child Health, Regenerative Medicine and Stem Cells, Fioredda, Francesca, Iacobelli, Simona, van Biezen, Anja, Gaspar, Bobby, Ancliff, Phil, Donadieu, Jean, Aljurf, Mahmoud, Peters, Christina, Calvillo, Michaela, Matthes-Martin, Susanne, Morreale, Giuseppe, van 't Veer-Tazelaar, Nelleke, de Wreede, Liesbeth, Al Seraihy, Amal, Yesilipek, Akif, Fischer, Alain, Bierings, Marc, Ozturk, Gulyuz, Smith, Owen, Veys, Paul, Ljungman, Per, Peffault de Latour, Régis, Sánchez de Toledo Codina, José, Or, Reuven, Ganser, Arnold, Afanasyev, Boris, Wynn, Robert, Kalwak, Krzysztof, Marsh, Judith, Dufour, Carlo, Severe Aplastic Anemia the Inborn Error, and the Pediatric Disease Working Parties of the European Society for Blood and Bone Marrow Transplantation (EBMT) and Stem Cell Transplant for Immunodeficiencies in Europe (SCETIDE), Haematologie, Child Health, Regenerative Medicine and Stem Cells, Fioredda, Francesca, Iacobelli, Simona, van Biezen, Anja, Gaspar, Bobby, Ancliff, Phil, Donadieu, Jean, Aljurf, Mahmoud, Peters, Christina, Calvillo, Michaela, Matthes-Martin, Susanne, Morreale, Giuseppe, van 't Veer-Tazelaar, Nelleke, de Wreede, Liesbeth, Al Seraihy, Amal, Yesilipek, Akif, Fischer, Alain, Bierings, Marc, Ozturk, Gulyuz, Smith, Owen, Veys, Paul, Ljungman, Per, Peffault de Latour, Régis, Sánchez de Toledo Codina, José, Or, Reuven, Ganser, Arnold, Afanasyev, Boris, Wynn, Robert, Kalwak, Krzysztof, Marsh, Judith, Dufour, Carlo, and Severe Aplastic Anemia the Inborn Error, and the Pediatric Disease Working Parties of the European Society for Blood and Bone Marrow Transplantation (EBMT) and Stem Cell Transplant for Immunodeficiencies in Europe (SCETIDE)

Published
2015

28. Hematopoietic stem cell transplantation for infantile osteopetrosis

Author

CTI Nierkens, Regenerative Medicine and Stem Cells, Child Health, Infection & Immunity, SCT onderzoek, Orchard, Paul J., Fasth, Anders L., Le Rademacher, Jennifer L., He, Wensheng, Boelens, Jaap Jan, Horwitz, Edwin M., Al-Seraihy, Amal, Ayas, Mouhab, Bonfim, Carmem M., Boulad, Farid, Lund, Troy, Buchbinder, David K., Kapoor, Neena, OBrien, Tracey A., Perez, Miguel A Diaz, Veys, Paul A., Eapen, Mary, CTI Nierkens, Regenerative Medicine and Stem Cells, Child Health, Infection & Immunity, SCT onderzoek, Orchard, Paul J., Fasth, Anders L., Le Rademacher, Jennifer L., He, Wensheng, Boelens, Jaap Jan, Horwitz, Edwin M., Al-Seraihy, Amal, Ayas, Mouhab, Bonfim, Carmem M., Boulad, Farid, Lund, Troy, Buchbinder, David K., Kapoor, Neena, OBrien, Tracey A., Perez, Miguel A Diaz, Veys, Paul A., and Eapen, Mary

Published
2015

Catalog

Books, media, physical & digital resources
See catalog results