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The double-weave structure of a fabric allows for the use of different materials and weave structures for the upper and lower layer, which can be advantageous in the functionalization of 3D printed textiles. Therefore, the aim of this research was to investigate the influence of simple and double-weave structures on the adhesion of 3D printed fabrics. From this perspective, we investigated the influence of different twill derivates and weft densities on the adhesion force. We produced fabrics specifically for this study and printed them with a polylactic acid filament using Fused Deposition Modeling technology. The T-peel test was performed to measure the adhesion, and the results were statistically analyzed. A morphological study of the surfaces and cross-sections of the 3D printed fabrics helped us interpret the results. We found that adhesion was higher for double fabrics when printed with a smaller z-distance, where the molten polymer reached the lower layer of the fabric and adhered to it. The opposite was confirmed when printing with a larger z-distance, where adhesion was higher for simple fabrics. Both weave and density had a significant effect on adhesion in all cases. Surprisingly, different twill derivatives generally had a greater influence on adhesion than density.