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35 results on '"ten Hacken, Elisa"'

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1. T-bet suppresses proliferation of malignant B cells in chronic lymphocytic leukemia.

2. Updates on the biology of chronic lymphocytic leukemia: introductory editorial.

3. Special issue on chronic lymphocytic leukemia: Prognostication and therapeutic options introductory editorial.

4. Generation of mouse models carrying B cell restricted single or multiplexed loss-of-function mutations through CRISPR-Cas9 gene editing.

5. Loss-of-function lesions impact B-cell development and fitness but are insufficient to drive CLL in mouse models.

6. Richter syndrome: novel insights into the biology of transformation.

7. Mitochondrial DNA Mutations as Natural Barcodes for Lineage Tracing of Murine Tumor Models.

8. In Vivo Modeling of CLL Transformation to Richter Syndrome Reveals Convergent Evolutionary Paths and Therapeutic Vulnerabilities.

9. Understanding CLL biology through mouse models of human genetics.

10. Activation of Notch and Myc Signaling via B-cell-Restricted Depletion of Dnmt3a Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia.

11. A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation.

12. High throughput single-cell detection of multiplex CRISPR-edited gene modifications.

13. The BET inhibitor GS-5829 targets chronic lymphocytic leukemia cells and their supportive microenvironment.

14. CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del(11q) CLL cells to dual BCR and PARP inhibition.

15. Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies.

16. SLAMF6 as a Regulator of Exhausted CD8 + T Cells in Cancer.

17. A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion.

18. The importance of B cell receptor isotypes and stereotypes in chronic lymphocytic leukemia.

19. Splicing modulation sensitizes chronic lymphocytic leukemia cells to venetoclax by remodeling mitochondrial apoptotic dependencies.

20. Functional and clinical relevance of VLA-4 (CD49d/CD29) in ibrutinib-treated chronic lymphocytic leukemia.

21. SnapShot: Chronic Lymphocytic Leukemia.

22. Calreticulin as a novel B-cell receptor antigen in chronic lymphocytic leukemia.

24. Ibrutinib modifies the function of monocyte/macrophage population in chronic lymphocytic leukemia.

25. Functional Differences between IgM and IgD Signaling in Chronic Lymphocytic Leukemia.

26. Ofatumumab and Lenalidomide for Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia: Correlation between Responses and Immune Characteristics.

27. HIF-1α regulates the interaction of chronic lymphocytic leukemia cells with the tumor microenvironment.

28. Microenvironment interactions and B-cell receptor signaling in Chronic Lymphocytic Leukemia: Implications for disease pathogenesis and treatment.

29. Microenvironment dependency in Chronic Lymphocytic Leukemia: The basis for new targeted therapies.

30. Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers.

31. Molecular pathways: targeting the microenvironment in chronic lymphocytic leukemia--focus on the B-cell receptor.

32. Targeting B-cell anergy in chronic lymphocytic leukemia.

33. Targeting the LYN/HS1 signaling axis in chronic lymphocytic leukemia.

34. HS1 has a central role in the trafficking and homing of leukemic B cells.

35. How the microenvironment shapes chronic lymphocytic leukemia: the cytoskeleton connection.

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