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There is much evidence pointing out eye movement alterations in several neurological diseases. To the best of our knowledge, this is the first video-oculography study describing potential alterations of eye movements in the post-COVID-19 condition. Visually guided saccades, memory-guided saccades, and antisaccades in horizontal axis were measured. In all visual tests, the stimulus was deployed with a gap condition. The duration of the test was between 5 and 7 min per participant. A group of n=9 patients with the post-COVID-19 condition was included in this study. Values were compared with a group (n=9) of healthy volunteers whom the SARS-CoV-2 virus had not infected. Features such as centripetal and centrifugal latencies, success rates in memory saccades, antisaccades, and blinks were computed. We found that patients with the post-COVID-19 condition had eye movement alterations mainly in centripetal latency in visually guided saccades, the success rate in memory-guided saccade test, latency in antisaccades, and its standard deviation, which suggests the involvement of frontoparietal networks. Further work is required to understand these eye movements' alterations and their functional consequences.

Partial vitreous liquefaction (PVL) is a common physical and biochemical degenerative change in the vitreous body in which the liquid component becomes separated from collagen fiber network and this might form the pocket of liquefaction known as lacuna. The main objective of this research is to investigate how the saccade movements influence flow dynamics of the PVL. A three-dimensional model of the vitreous cavity is subjected to saccadic movement and the numerical simulations for various saccade amplitudes and volume fractions are performed. We consider concentric and eccentric configurations of the PVL with the initial spherical shape inside a spherical cavity. In this paper, a specific 3D numerical solver is developed to capture the interface effects and dynamic characteristics of a two-phase viscoelastic-Newtonian fluid flow by using the OpenFOAM CFD. The code is based on a set of time-dependent non-linear partial differential equations (PDE) such as continuity, momentum and constitutive relation for polymeric stresses tensor. The finite volume method with a modified volume-of-fluid model and dynamic mesh technique are used to solve PDEs. Firstly, the validity of the present numerical model was verified by comparing the obtained results with the analytical solutions which demonstrated remarkable agreement. Then, the time- and space-dependent velocity field, shear stress and normal stress distributions were computed and how the PVL responds to the saccadic motions was discussed., (Copyright © 2020 Elsevier Ltd. All rights reserved.)