1. Co-morbid Insomnia and Sleep Apnea (COMISA) in a large sample of Iranian: prevalence and associations in a sleep clinic population.
- Author
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Khazaie H, Aghazadeh M, Zakiei A, Maazinezhad S, Tavallaie A, Moghbel B, Azarian M, Mozafari F, Norouzi E, Sweetman A, and Sharafkhaneh A
- Subjects
- Humans, Male, Iran epidemiology, Female, Middle Aged, Adult, Aged, Sleep Apnea, Obstructive epidemiology, Cross-Sectional Studies, Sleep Initiation and Maintenance Disorders epidemiology, Comorbidity, Polysomnography
- Abstract
Background: Sleep apnea (SA) and insomnia (INS) are prevalent sleep disorders among referrals to sleep clinics. People with comorbid insomnia and sleep apnea (COMISA) suffer both disorders simultaneously. The epidemiology of COMISA is not well known in the Middle East including Iran. We hypothesized that COMISA is prevalent in metropolitan sleep clinic cohorts in Iran., Method: The records of patients aged < 95 years referred to sleep disorders centers in four large metropolitan areas including Kermanshah, Tabriz, Shiraz, and Ahvaz were examined. Polysomnography (PSG) was performed in all these patients in specialized centers and the results were scored by a trained technician and interpreted by a sleep specialist. SA was defined as an Apnea-Hypopnea Index (AHI ≥ 5), INS was defined by psychiatrists according to self-report and clinical interviews, and COMISA was defined if both disorders were present. Participants with neither condition were included in as comparator group. One-way ANOVAs, correlation, and linear/logistic regression analyses were used., Results: This study included 1807 patients (Mean age 49.3, SE ± 13.7; 38.8% Female). Comparator, INS, SA and COMISA made up 7.2%, 16%, 50.2% and 26.6% of the sample, respectively. Logistic regression analyses showed that male gender, older age, and increasing neck circumference, but not BMI, were associated with COMISA. Epworth Sleepiness Scale scores were lower in INS (5.39 ± 5.78) compared to the other three groups., Conclusion: COMISA is a prevalent condition in metropolitan sleep centers in Iran among participants referred to sleep centers. The data showed that male gender and age were associated significantly with COMISA., Competing Interests: Declarations Ethics approval and consent to participate The Review Board of the Kermanshah University of Medical Sciences (Ethical Approval ID: IR.KUMS.REC.1401.423) approved the study, which was performed in accordance with the ethical principles laid down in the seventh and current edition (2013) of the Declaration of Helsinki. Participant s’ signed the written informed consent sheet and gave their assent to participate in the present study. Consent for publication For all details include data and images relating to an individual person, written informed consent for the publication of these details and any potentially identifiable images were obtained from that person. Consent to participate Participants were fully informed about the aims and the procedure of the study, and the anonymous data handling. They all signed the written informed consent sheet to participate in the present study., (© 2024. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)
- Published
- 2024
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