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Objective: Human milk (HM) is the most necessary and complete food for infants and their survival. It is a dynamic system influenced by different factors such as the sex of the infant. The study of the factors affecting the composition of mother's milk can provide us better insight into the nutritional needs of infants with different sex and improve the nutrition of babies who do not have access to HM. This study aimed to study the effects of infant sex on mother's milk composition. Methods: Sixty-one mother's milk samples were collected from mothers with female or male infants and divided into two (32 sons, 29 daughters) groups. The samples were analyzed by the Lacto-Scan milk analyzer and the obtained data were compared between the groups. Results: The results showed that the mean fat content in the milk samples of mothers with female infants (daughters group) (3.42 ± 1.80%) was significantly ( p  = 0.029) higher than that in mothers with male infants (sons group) (2.53 ± 1.18%). However, the sons group had higher ( p  = 0.024) levels of salts (0.76 ± 0.14%) compared with the daughters group (0.67 ± 0.18%). There was no significant ( p  > 0.05) difference in other indices between the groups. Conclusions: The sex of the infant is one of the important factors affecting the composition of mother's milk. The difference in the composition of mother's milk may reflect the differences in metabolic substrate needed for optimal growth and development in female and male infants.

Background: Despite advances in the treatment of cardiovascular diseases in recent decades, patients experience high levels of depression, anxiety, stress, and insomnia. Since the calming effect of Melissa officinalis (MO) has been known, this study aimed to determine the effects of MO supplementation on depression, anxiety, stress, and sleep disturbances in patients with chronic stable angina (CSA)., Methods: In this double-blind placebo-controlled clinical trial, 80 patients with CSA were divided randomly into two groups (taking 3 g MO supplement or placebo daily for 8 weeks). The shortened 21-item version of the depression, anxiety and stress scale (DASS-21) test and Pittsburgh sleep quality index were done before and after the intervention., Results: At the end of the study, the intervention group receiving MO capsules had a significant reduction in scores of depression, anxiety, stress, and total sleep disturbance, compared with the placebo group (P < 0.05)., Conclusions: The results showed that 8-week supplementation with 3 g MO can decrease depression, anxiety, stress, and sleep disorder in patients with CSA., (Copyright © 2018 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.)