1. Serodiagnosis of dengue virus infection in patients presenting to a tertiary care hospital.
- Author
-
Neeraja M, Lakshmi V, Teja VD, Umabala P, and Subbalakshmi MV
- Subjects
- Adolescent, Adult, Aged, Child, Dengue mortality, Dengue virology, Female, Humans, Immunoglobulin G blood, Immunoglobulin M blood, India epidemiology, Male, Middle Aged, Serologic Tests, Severe Dengue diagnosis, Severe Dengue mortality, Severe Dengue physiopathology, Severe Dengue virology, Shock, Septic diagnosis, Shock, Septic mortality, Shock, Septic virology, Academic Medical Centers, Antibodies, Viral blood, Dengue diagnosis, Dengue physiopathology, Dengue Virus immunology
- Abstract
Dengue is an acute infectious disease of viral etiology. It is probably one of the most important arthropod borne viral disease in terms of human morbidity and mortality. The spectrum of disease ranges from self-limited dengue fever to more severe forms of dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). Laboratory diagnosis of dengue virus infection mainly depends on detection of virus specific antibodies. The aim of the study was to correlate the serological results with clinical presentation in patients with a diagnosis of dengue. Eleven out of 15 (73.3%) patients with DHF and DSS had secondary antibody response and mortality was 100% in these patients.
- Published
- 2006
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