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Liposomal bupivacaine has reportedly been used as an adjunct for perioperative pain management in total knee replacement (TKR). The purpose of our single-blind, prospective study is to show that wound infiltration with long-acting liposomal bupivacaine during TKR will shorten length of stay (LOS) as compared with standard bupivacaine injection and spinal anesthetic with or without spinal narcotic. A total of 195 patients were randomized into three groups: wound infiltration with bupivacaine and a spinal with narcotic (Group 1, N  = 65), wound infiltration with liposomal bupivacaine and a spinal without narcotic (Group 2, N  = 67), and bupivacaine wound infiltration with a spinal without narcotic (Group 3, N  = 64). The groups were then compared with look for any benefit in using the liposomal bupivacaine with regard to LOS, pain control, function, and complications. There was a trend toward a decreased LOS (days) in the liposomal bupivacaine (Group 2) with a mean LOS of 1.83 as compared with wound infiltration with bupivacaine with spinal narcotic LOS of 2.04 (Group 1) and without spinal narcotic LOS of 1.94 (Group 3). These results were not statistically significant ( p  = 0.37). Patient-reported pain scores were no different between the three groups. The daily narcotic usage (morphine equivalents) during the hospitalization was statistically highest in the liposomal bupivacaine group at 77.2 versus 55.0 in Group 1 and 68.1 in Group 3 ( p  = 0.025). Nausea or vomiting was most common in Group 1 at 42%, followed by 28% in Group 2 and 22% in Group 3. Pruritus was most common in the spinal narcotic group at 38% versus Group 2 at 14% and Group 3 at 11%.Liposomal bupivacaine showed a trend toward a decreased LOS, but this was not statistically significant. There was no difference in pain scores reported by these patients. In conclusion, we cannot justify the extra cost of liposomal bupivacaine as compared with plain bupivacaine as an adjunct for perioperative pain management in TKR patients., Competing Interests: None., (Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.)

Elderly patients undergoing both elective and nonelective hip arthroplasty contribute markedly to health care spending, and the current aging population is likely to require even more resources. Several national joint replacement registries show a lower risk of revision surgery in patients older than 75 years who received cemented femoral components compared with cementless implants for primary total hip arthroplasty. Despite a higher incidence of early periprosthetic femoral fracture, noncemented femoral components are being used with increasing frequency in elderly patients worldwide. Improvements in cementing technique and modifications to cemented stem design over several decades allow surgeons to obtain femoral component fixation in poor-quality bone with a relatively low risk of complications. Achieving durable cemented stem fixation requires the surgeon to understand the basic handling properties of cement, how to prepare the femoral bone, and differences in stem design and surface finish.

Purpose: The existing literature lacks a functional outcomes study addressing instrumented posterior lumbar fusion surgery for isthmic spondylolisthesis in physically active patients. Presently, spinal surgeons can provide only anecdotal advice when discussing operative outcomes with these patients. This is a nonrandomized analysis of consecutive military servicemen treated operatively for chronic back pain and low-grade isthmic spondylolisthesis with single-level lumbar disc degeneration with emphasis on functional outcomes. The purpose was to evaluate patient-assessed function/pain/satisfaction and military job performance in U.S. servicemen treated with posterior lumbar interbody fusion (PLIF)., Methods: Thirty consecutive U.S. military servicemen with chronic low back pain and low-grade lumbar isthmic spondylolisthesis were referred to the same surgeon at a military treatment facility. All servicemen were treated operatively with instrumented PLIF using autogenous iliac crest bone graft, one or two nonthreaded interbody cages (Brantigan or Harms), and a four-pedicle screw/rod construct. A concomitant bilateral posterolateral fusion was performed in all 30 cases. The average follow-up time was 15 months (range 12-48 months). Twenty-five of the 30 servicemen completed a functional outcomes questionnaire (American Academy of Orthopaedic Surgeons/Scoliosis Research Society) with emphasis on pre- and posttreatment function, pain, and satisfaction. The servicemen were also evaluated using standard military job performance parameters., Results: Three of the 30 servicemen (10%) requested and received a disability discharge from the military for back pain that continued throughout the postoperative period and prevented return to military duty. An additional 8 of the original 30 soldiers (27%) required some form of permanent physical activity limitation (situps/pushups/running/lifting) to permit their return to military duty, and 19 of 30 (63%) soldiers were able to return to full and unrestricted military duty after surgery. Those soldiers who were able to return to unrestricted military duty (n = 19) did so at an average of 6 months post treatment (range 2-16 months). Of the soldiers who were able to return to military duty, 21 of 30 (70%) were able to complete the posttreatment military physical fitness test at an average of 8 months postoperatively (range 2-32 months). No significant differences were observed between premorbid and postsurgical physical fitness test scores. There was a trend toward lower postsurgical scores. Complications included dural tear (n = 4), unilateral transient lower extremity paresthesia (n = 1), and wound seroma requiring reoperation (n = 1)., Conclusions: In this nonrandomized study of 30 U.S. servicemen with chronic low back pain, low-grade isthmic spondylolisthesis, and single-level lumbar disc degeneration, instrumented PLIF surgery was associated with a high rate of return to functional military duty. Outcomes with respect to posttreatment pain, function, and satisfaction were high in patients treated with instrumented PLIF.