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101 results on '"Poliomyelitis metabolism"'

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1. Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate.

2. Ribosomal protein RACK1 enhances translation of poliovirus and other viral IRESs.

3. A Redundant Mechanism of Recruitment Underlies the Remarkable Plasticity of the Requirement of Poliovirus Replication for the Cellular ArfGEF GBF1.

4. Multiple poliovirus-induced organelles suggested by comparison of spatiotemporal dynamics of membranous structures and phosphoinositides.

5. Selection of cellular genetic markers for the detection of infectious poliovirus.

6. T-bet, but not Gata3, overexpression is detrimental in a neurotropic viral infection.

7. CRISPR/Cas9-mediated gene knockout screens and target identification via whole-genome sequencing uncover host genes required for picornavirus infection.

8. Covalently circularized nanodiscs for studying membrane proteins and viral entry.

9. Loss of galectin-3 decreases the number of immune cells in the subventricular zone and restores proliferation in a viral model of multiple sclerosis.

10. Inhibition of poliovirus-induced cleavage of cellular protein PCBP2 reduces the levels of viral RNA replication.

11. mRNA decapping enzyme 1a (Dcp1a)-induced translational arrest through protein kinase R (PKR) activation requires the N-terminal enabled vasodilator-stimulated protein homology 1 (EVH1) domain.

12. Bacterial lipopolysaccharide binding enhances virion stability and promotes environmental fitness of an enteric virus.

13. Elevated expression of prostaglandin E2 synthetic pathway in skeletal muscle of prior polio patients.

14. Upregulation of voltage-gated Ca2+ channels in mouse astrocytes infected with Theiler's murine encephalomyelitis virus (TMEV).

15. Ribosomal protein S25 dependency reveals a common mechanism for diverse internal ribosome entry sites and ribosome shunting.

16. Increased long chain acyl-Coa synthetase activity and fatty acid import is linked to membrane synthesis for development of picornavirus replication organelles.

17. Valosin-containing protein (VCP/p97) is required for poliovirus replication and is involved in cellular protein secretion pathway in poliovirus infection.

18. Intracellular vesicle acidification promotes maturation of infectious poliovirus particles.

19. Complex dynamic development of poliovirus membranous replication complexes.

20. Poliovirus unlinks TIA1 aggregation and mRNA stress granule formation.

21. Re-localization of cellular protein SRp20 during poliovirus infection: bridging a viral IRES to the host cell translation apparatus.

22. Calcium flux between the endoplasmic reticulum and mitochondrion contributes to poliovirus-induced apoptosis.

23. Axon-myelin interactions during a viral infection of the central nervous system.

24. Receptor-dependent and -independent axonal retrograde transport of poliovirus in motor neurons.

25. Inhibition of cytoplasmic mRNA stress granule formation by a viral proteinase.

26. Poliovirus infection blocks ERGIC-to-Golgi trafficking and induces microtubule-dependent disruption of the Golgi complex.

27. Expression of L* protein of Theiler's murine encephalomyelitis virus in the chronic phase of infection.

28. Evidence for emergence of diverse polioviruses from C-cluster coxsackie A viruses and implications for global poliovirus eradication.

29. Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivity.

30. Proteolytic cleavage of the p65-RelA subunit of NF-kappaB during poliovirus infection.

31. Translation of eukaryotic translation initiation factor 4GI (eIF4GI) proceeds from multiple mRNAs containing a novel cap-dependent internal ribosome entry site (IRES) that is active during poliovirus infection.

32. Immunohistochemical detection of osteopontin in the spinal cords of mice with Theiler's murine encephalomyelitis virus-induced demyelinating disease.

33. The double-stranded RNA-activated protein kinase mediates viral-induced encephalitis.

34. Quantitative RT-PCR ELISA to determine the amount and ratio of positive- and negative strand viral RNA synthesis and the effect of guanidine in poliovirus infected cells.

35. Acute encephalitis, a poliomyelitis-like syndrome and neurological sequelae in a hamster model for flavivirus infections.

36. ICAM-1 is crucial for protection from TMEV-induced neuronal damage but not demyelination.

37. Unstable receptors disappear from cell surface during poliovirus infection.

38. Immunofluorescence analysis of poliovirus receptor expression in Peyer's patches of humans, primates, and CD155 transgenic mice: implications for poliovirus infection.

39. Age-dependent poliomyelitis in mice is associated with respiratory failure and viral replication in the central nervous system and lung.

40. Central nervous system chemokine expression during Theiler's virus-induced demyelinating disease.

41. Spontaneous demyelinating myelopathy in aging laboratory mice.

42. Monoclonal remyelination-promoting natural autoantibody SCH 94.03: pharmacokinetics and in vivo targets within demyelinated spinal cord in a mouse model of multiple sclerosis.

43. Fibrin deposition in the central nervous system correlates with the degree of Theiler's murine encephalomyelitis virus-induced demyelinating disease.

44. The outcome of poliovirus infections in K562 cells is cytolytic rather than persistent after hemin-induced differentiation.

45. DNA binding domain and subunit interactions of transcription factor IIIC revealed by dissection with poliovirus 3C protease.

46. Human protein Sam68 relocalization and interaction with poliovirus RNA polymerase in infected cells.

47. Phosphorylation state of the cap-binding protein eIF4E during viral infection.

48. Contractile properties in single muscle fibres from chronically overused motor units in relation to motoneuron firing properties in prior polio patients.

49. Expression of poliovirus receptor in human spinal cord and muscle.

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