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Objectives: To assess coronary artery calcification (CAC) on non-contrast non-ECG-gated CT thorax (NC-NECG-CTT) and to evaluate its correlation with short-term risk of cardiovascular disease (CVD) events and death., Methods: Single-institution retrospective study including all patients 40-70 years old who underwent NC-NECG-CTT over a period of 6 months. Individuals with known CVD were excluded. The presence of CAC was assessed and quantified by the Agatston score (CACS). CAC severity was defined as mild (< 100), moderate (100-400), or severe (> 400). CVD events (including CVD death, myocardial infarction, revascularisation procedures, ischaemic stroke, acute peripheral atherosclerotic ischaemia), and all-cause mortality over a median of 3.5 years were recorded. Cox proportional-hazards regression modelling was performed including CACS, age, gender and CVD risk factors (smoking, hypertension, diabetes mellitus, dyslipidaemia, and family history of CVD)., Results: Of the total 717 eligible cases, 325 (45%) had CAC. In patients without CAC, there was only one CVD event, compared to 26 CVD events including 5 deaths in patients with CAC. The presence and severity of CAC correlated with CVD events (p < 0.001). A CACS > 100 was significantly associated with both CVD events, hazard ratio (HR) 5.74, 95% confidence interval: 2.19-15.02; p < 0.001, and all-cause mortality, HR 1.7, 95% CI: 1.08-2.66; p = 0.02. Ever-smokers with CAC had a significantly higher risk for all-cause mortality compared to never-smokers (p = 0.03), but smoking status was not an independent predictor for CVD events in any subgroup category of CAC severity., Conclusions: The presence and severity of CAC assessed on NC-NECG-CTT correlates with short-term cardiovascular events and death., Key Points: • Patients aged 40-70 years old without known CVD but with CAC on NC-NECG-CTT have a higher risk of CVD events compared to those without CAC. • CAC (Agatston) score above 100 confers a 5.7-fold increase in the risk of short-term CVD events in these patients. • The presence and severity of CAC on NC-NECG-CTT may have prognostic and therapeutic implications., (© 2023. The Author(s), under exclusive licence to European Society of Radiology.)

Background: Vessel sizing and calcium detection by intracoronary imaging informs optimal strategy during coronary interventions, but image interpretation and analysis software vary considerably between platforms. We compared the interobserver variability of clinicians with a range of experience in assessing co-registered optical coherence tomography (OCT) and 20 MHz solid state intravascular ultrasound (IVUS) vessel/ lumen geometry and quantitative plaque data., Methods: Co-registered OCT and IVUS frames at the minimum lumen area (MLA) and 5 frames at 2 mm intervals upstream and downstream were read blinded by an expert, consultant, interventional fellow and registrar to define vessel and lumen sizes, plaque characteristics (arc of calcium and lipid) and presence of OCT-defined thin-capped fibroatheroma (TCFA)., Results: Overall, 143 paired frames of OCT and IVUS were analysed. Excellent consistency was seen for all OCT measures of vessel/luminal geometry irrespective of experience (all intraclass correlation coefficients (ICC) >0.89). Inexperience compromised ICC for IVUS (lumen area ICC 0.56; vessel size ICC 0.65) and overestimated lumen size compared to expert (p < 0.001). Calcium arc agreement for OCT and IVUS was equally strong for all but the most inexperienced reader (ICC >0.84). OCT lipid arc agreement was moderate for experienced readers but poor for all grades of reader with IVUS (ICC 0.24-0.43). OCT-TCFA agreement was moderate between expert and consultant (κ = 0.55) and poor for less experienced readers., Conclusion: OCT dimensions are minimally affected by observer experience and more consistent than IVUS. Inexperienced readers oversize with IVUS. Calcium arc is dependably assessed by IVUS and OCT by all but the most inexperienced reader., Competing Interests: Declaration of competing interest SPH has acted as a consultant for Abbott Vascular. NEJW previously acted as a consultant to and subsequently became an employee of Abbott Vascular. There are no other conflicts of interest to report. The study protocol, reader selection, data acquisition and analysis were performed completely independently from Abbott Vascular. The final manuscript was reviewed by Dr. Nick West, who provided comments, but the final editorial decision rested with the senior last author, Dr. Hoole., (Copyright © 2022 Elsevier Inc. All rights reserved.)

Introduction: Sun protection, particularly the appropriate use of sunscreens is an important modifiable risk factor in the prevention of skin cancers. Our aim was to assess the current knowledge levels regarding sun protection, across plastic surgeons in the UK., Methods: A 12-point questionnaire based on the points contained in the patient information packs on sun protection produced by the British Association of Dermatology was circulated electronically amongst 551 BAPRAS members. We received 73 responses (13.3%). Questions were formulated around the basic information patients would expect to receive from a skin cancer specialist at the time of the diagnosis., Results: On average, participants could answer only 52.4% of the questions correctly. Only 9.7% (95% CI 3-17) of participants could accurately quantify the role of UV exposure in causation of melanoma. A total of 37.5% correctly identified the duration of action of sunscreen to be 3-4 h. Half of the participants were not aware that geographical conditions like altitude and latitude, as well as shade, could alter sun protection. A similar number could not answer questions related to the protective action of clothing., Conclusion: As principal stakeholders in the treatment and outcomes of skin cancer patients, plastic surgeons could be at the forefront of influencing patients' behaviour regarding sun protection measures. The results demonstrate a need for better awareness and education regarding the knowledge of sunscreens and UV protection. Improved education would lead to health benefits for patients and their relatives and influence the primary prevention of this enlarging health issue of skin cancer., (Copyright © 2012 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.)