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This article summarizes the experience of managing patients with COVID-19-associated pneumonia treated in one of the intensive care units of a multidisciplinary hospital with and without a heated oxygen-helium mixture. It has been shown that the use of a heated oxygen-helium mixture in the complex therapy of pneumonia caused by SARS-CoV-2 is effective. A comparative analysis of the clinical manifestations of the disease and the results of laboratory tests in the main and control groups of patients confirm with a high degree of reliability the improvement of blood oxygenation, the normalization of the acid-base balance and the positive dynamics of the main parameters, which ultimately increases the efficacy and reduces the time of treatment., Competing Interests: CONFLICT OF INTERESTSThe authors declare that they do not have a conflict of interest., (© Pleiades Publishing, Inc. 2022, ISSN 0362-1197, Human Physiology, 2022, Vol. 48, No. 7, pp. 863–870. © Pleiades Publishing, Inc., 2022.Russian Text © The Author(s), 2021, published in Aviakosmicheskaya i Ekologicheskaya Meditsina, 2021, Vol. 55, No. 1, pp. 51–58.)

This paper presents a comparison of simple self-consistent theory data and experimental results aimed to study the influence of the anode voltage on the frequency of the subterahertz gyrotron with the goal of frequency stabilization. Numerical simulations of the electron beam formation and beam-wave interaction in a 0.26 THz gyrotron are performed. The experimental dependence of the gyrotron frequency tuning on mod-anode voltage is in agreement with theoretical predictions.

We present the first experimental results of the study on a novel second harmonic THz-band double-beam gyrotron. The tube has demonstrated a stable single-mode operation with output parameters that are appropriate for the next-generation 1.2 GHz dynamic nuclear polarization-nuclear magnetic resonance spectroscopy. Besides the design mode (TE 8,5 ), a series of other fundamental and second harmonic modes have been excited. This makes the new gyrotron a versatile radiation source, which can be used also in other applications of the high-power science and technologies.

A 263 GHz continuous-wave (CW) gyrotron was developed at the IAP RAS for future applications as a microwave power source in Dynamic Nuclear Polarization / Nuclear magnetic resonance (DNP/NMR) spectrometers. A new experimental facility with a computerized control was built to test this and subsequent gyrotrons. We obtained the maximum CW power up to 1 kW in the 15 kV/0.4 A operation regime. The power about 10 W, which is sufficient for many spectroscopic applications, was realized in the low current 14 kV/0.02 A regime. The possibility of frequency tuning by variation of the coolant temperature about 4 MHz/1 °C was demonstrated. The spectral width of the gyrotron radiation was about 10(-6).

Record-breaking high power coherent radiation at a subterahertz frequency region from a gyrotron utilizing second harmonic resonance modes was attained with a simple cavity. In order to aim at high power and high frequency simultaneously, the oscillation mode was selected carefully enough to realize stable radiation free from mode competition. The cavity radius was determined from the viewpoints of the oscillation frequency, the coupling coefficient between the electron beam, and the rf-electric field. The cavity length was also optimized for the highest perpendicular efficiency. In addition, a new electron gun which is capable of generating a thin laminar beam for a large current was introduced. Consequently, single mode second harmonic radiation with powers of 52 and 37 kW at frequencies of about 349 and 390 GHz, respectively, was achieved.

Coherent terahertz high-harmonic radiation has been obtained in a gyrotron with an axis-encircling electron beam. An electron-optical system with a cusp gun and a following drift section of adiabatic magnetic compression with an area factor of 3000 provides the formation of an 80-keV/0.7-A beam of gyrating electrons in a wide range of voltages and magnetic fields. Stable single-mode generation with a power of 0.3-1.8 kW in microsecond pulses is detected at four frequencies in the range 0.55-1.00 THz at resonant magnetic fields 10.5-14 T.