Search

In recent decades, primal-dual neural networks, as a special type of recurrent neural networks, have received great success in real-time manipulator control. However, noises are usually ignored when neural controllers are designed based on them, and thus, they may fail to perform well in the presence of intensive noises. Harmonic noises widely exist in real applications and can severely affect the control accuracy. This work proposes a novel primal-dual neural network design that directly takes noise control into account. By taking advantage of the fact that the unknown amplitude and phase information of a harmonic signal can be eliminated from its dynamics, our deliberately designed neural controller is able to reach the accurate tracking of reference trajectories in a noisy environment. Theoretical analysis and extensive simulations show that the proposed controller stabilizes the control system polluted by harmonic noises and converges the position tracking error to zero. Comparisons show that our proposed solution consistently and significantly outperforms the existing primal-dual neural solutions as well as feedforward neural one and adaptive neural one for redundancy resolution of manipulators.

Protein-protein interactions (PPIs) play a central role in many biological processes. Although a large amount of human PPI data has been generated by high-throughput experimental techniques, they are very limited compared to the estimated 130 000 protein interactions in humans. Hence, automatic methods for human PPI-detection are highly desired. This work proposes a novel framework, i.e., Low-rank approximation-kernel Extreme Learning Machine (LELM), for detecting human PPI from a protein's primary sequences automatically. It has three main steps: 1) mapping each protein sequence into a matrix built on all kinds of adjacent amino acids; 2) applying the low-rank approximation model to the obtained matrix to solve its lowest rank representation, which reflects its true subspace structures; and 3) utilizing a powerful kernel extreme learning machine to predict the probability for PPI based on this lowest rank representation. Experimental results on a large-scale human PPI dataset demonstrate that the proposed LELM has significant advantages in accuracy and efficiency over the state-of-art approaches. Hence, this work establishes a new and effective way for the automatic detection of PPI.