1. Solid variant of primary effusion lymphoma in successfully treated HIV infection: a case report.
- Author
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Mylona E, Baraboutis IG, Georgiou O, Rondogianni D, Lekakis LJ, Papastamopoulos V, Apostolidis I, and Skoutelis AT
- Subjects
- Adult, HIV Infections complications, HIV Infections immunology, HIV-1 drug effects, Humans, Lymphoma, AIDS-Related virology, Lymphoma, Primary Effusion virology, Male, Treatment Outcome, Anti-HIV Agents therapeutic use, HIV Infections drug therapy, Herpesvirus 8, Human, Lymphoma, AIDS-Related pathology, Lymphoma, Primary Effusion pathology
- Abstract
Primary effusion lymphoma (PEL) is a unique form of non-Hodgkin lymphoma, mainly met in severely immunocompromised, HIV-positive patients. PEL is aetiologically related to human herpes virus-8 (HHV-8) and it usually presents as a lymphomatous body cavity effusion in the absence of a solid tumour mass. Recently, cases of HIV-positive patients with HHV-8-positive solid tissue lymphomas, not associated with an effusion, have been reported (solid variant of PEL). The prognosis of PEL is reported to be poor. We report a case of an HIV-positive patient with a typical solid variant of PEL without effusion. Interestingly, his disease developed while being on stable antiretroviral therapy (ART) with high CD4 counts. He had a relatively long survival with chemotherapy and ART. more...
- Published
- 2008
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