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Ultrasound is commonly utilized to determine the dynamic Young's moduli for estimating material deterioration or quantifying material parameters. This is either done with a resonance frequency analysis or ultrasound for rock or concrete specimens in geophysics or civil engineering. For ultrasound, these are typically cylindrical specimens measured in a through-transmission arrangement. However, this method presents some challenges, such as the need to accurately determine the onset of each wave mode and to calibrate system latency. To overcome these challenges, this study introduces a novel method that utilizes wavefield simulation and full-waveform inversion to estimate p- and s-wave, also called compression and shear wave, velocities. Where the traditional method requires two measurements, this innovative approach requires only one measurement with a single p-wave transducer. The s-wave velocity is estimated considering mode conversions within the specimen. High-fidelity ultrasound simulations are necessary for this approach. For that reason, the spatially distributed excitation of the ultrasound transducer is characterized by a laser Doppler vibrometer measurement. This led to a good estimate of the directivity pattern of the ultrasound transducer. The inverse problem for determining p- and s-wave velocity was solved successfully using a suitable misfit or cost function, the so-called graph-optimal-transport misfit. The specimens for the proof of concept study include six different metals. The precision of the estimated velocities using full-waveform inversion was compared with manual picking. As the simulated and measured waveforms matched well, this study can be seen as a starting point for material parameter determination for more complex geometries and heterogeneous materials using full-waveform inversion., Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Simon Schmid reports financial support was provided by Technical University of Munich. Simon Schmid reports a relationship with Technical University of Munich that includes: employment., (Copyright © 2023 Elsevier B.V. All rights reserved.)

Abstract: A 99m Tc-DPD bone scintigraphy with SPECT/CT was performed in a 64-year-old woman with intrahepatic cholangiocarcinoma to exclude osseous metastases. The images demonstrated central focal tracer uptake in the left lung without any visible morphological correlate in the low-dose CT scan. For further clarification, a contrast-enhanced CT scan was carried out, which revealed a subsegmental pulmonary artery embolism in the left lower lobe. Subsequently, the patient was therapeutically anticoagulated. This case highlights the importance of clarifying focal pulmonary uptake in order not to overlook concomitant diseases., Competing Interests: Conflicts of interest and sources of funding: none declared., (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)

We present a general concept for evolutionary, collaborative, multiscale inversion of geophysical data, specifically applied to the construction of a first-generation Collaborative Seismic Earth Model. This is intended to address the limited resources of individual researchers and the often limited use of previously accumulated knowledge. Model evolution rests on a Bayesian updating scheme, simplified into a deterministic method that honors today's computational restrictions. The scheme is able to harness distributed human and computing power. It furthermore handles conflicting updates, as well as variable parameterizations of different model refinements or different inversion techniques. The first-generation Collaborative Seismic Earth Model comprises 12 refinements from full seismic waveform inversion, ranging from regional crustal- to continental-scale models. A global full-waveform inversion ensures that regional refinements translate into whole-Earth structure.