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Objectives: The purpose of this study was to evaluate the effectiveness of dental caries segmentation on the panoramic radiographs taken from children in primary dentition, mixed dentition, and permanent dentition with Artificial Intelligence (AI) models developed using the deep learning method., Methods: This study used 6075 panoramic radiographs taken from children aged between 4 and 14 to develop the AI model. The radiographs included in the study were divided into three groups: primary dentition (n: 1857), mixed dentition (n: 1406), and permanent dentition (n: 2812). The U-Net model implemented with PyTorch library was used for the segmentation of caries lesions. A confusion matrix was used to evaluate model performance., Results: In the primary dentition group, the sensitivity, precision, and F1 scores calculated using the confusion matrix were found to be 0.8525, 0.9128, and 0.8816, respectively. In the mixed dentition group, the sensitivity, precision, and F1 scores calculated using the confusion matrix were found to be 0.7377, 0.9192, and 0.8185, respectively. In the permanent dentition group, the sensitivity, precision, and F1 scores calculated using the confusion matrix were found to be 0.8271, 0.9125, and 0.8677, respectively. In the total group including primary, mixed, and permanent dentition, the sensitivity, precision, and F1 scores calculated using the confusion matrix were 0.8269, 0.9123, and 0.8675, respectively., Conclusions: Deep learning-based AI models are promising tools for the detection and diagnosis of caries in panoramic radiographs taken from children with different dentition.

Objective: Chemotherapy and radiotherapy, used to treat childhood hematological malignancies (acute lymphocytic leukemia [ALL] and acute myelocytic leukemia [AML]) can negatively affect oral tissues and organs. This study aimed to evaluate the oral health-related quality of life in children with ALL/AML., Materials and Methods: A total of 99 children, including 49 undergoing ALL/AML (41 with ALL and eight with AML) and 50 healthy volunteers, were included in this cross-sectional study. The mean age of the entire study group was 78.63 ± 34.41 months. The mean age of the ALL/AML and control groups was 87.12 ± 35.04 and 70.95 ± 34.85 months, respectively. The Simplified Oral Hygiene Index (SOHI), the Decayed, Missing, and Filled Teeth (DMFT/dmft) index, and the Turkish version of the Early Childhood Oral Health Impact Scale (ECOHIS-T) were administered to all children. The data were analyzed using SPSS software (version 22.0). The Pearson chi-square and Fisher's exact tests were used to compare demographic data., Results: The age and gender distributions of the two groups were similar. According to ECOHIS-T, the children in the ALL/AML group had significantly more loss of function (eating, drinking, sleeping, etc.) than those in the control group., Conclusions: Oral health and self-care were negatively affected by childhood ALL/AML and its treatment., (© 2023 The Authors. Oral Diseases published by Wiley Periodicals LLC.)

Aim: To assess trends and seasonal variation of dental trauma by using the Google Trends data., Design: Google Trends was used to obtain relative search volume (RSV) of search terms such as dental trauma, broken tooth, chipped tooth, knocked-out tooth, avulsed tooth, and gum trauma. The search strategy was set to the time period (January 2004 to December 2019), region (worldwide, the United States, the UK, Australia, Canada, New Zealand, Ireland, and Turkey), Web search, and all categories. Seasonal variation was evaluated using the cosinor analysis., Results: The worldwide RSV values of broken tooth, chipped tooth, knocked-out tooth, and avulsed tooth have shown a general increase in recent years with an upward forecast line. The RSV values of dental trauma have shown a general increase in recent years with a plateau forecast line, and gum trauma has shown a stable trend with a plateau forecast line. Seasonal variation of chipped tooth, broken tooth, dental trauma, knocked-out tooth, avulsed tooth, and gum trauma was not found statistically significant in any of the countries (p > .025). The top related queries of chipped tooth and broken tooth were about pain, fix/repair, and cost. The top related topics for avulsed tooth and knocked-out tooth are about infant, child, toddler, and primary tooth., Conclusions: People's interest on dental trauma, broken tooth, chipped tooth, knocked-out tooth, and avulsed tooth has shown a general increase in recent years without showing a seasonal pattern. Healthcare professionals should pay more attention to people's concerns and informational needs., (© 2021 BSPD, IAPD and John Wiley & Sons Ltd.)

Background: This study compared the ability of four remineralization agents to restore demineralised enamel lesions in permanent human incisors., Methods: In total, 40 teeth were included in the study. Two samples were obtained from each tooth. The 80 samples were divided into 10 groups (n = 8 per group). The right halves of the teeth were controls solely subjected to demineralisation and stored in artificial saliva for the duration of the experiment. The left halves of the teeth were remineralised using a 5% NaF-containing fluoride varnish (GC MI varnish; GC Corp.), a toothpaste containing casein phosphopeptide and amorphous calcium (GC tooth mousse; GC Corp.), a water-soluble remineralisation paste containing fluoride, hydroxyapatite, xylitol (Remin Pro; Voco), and ROCS remineralising gel containing Ca, magnesium(Mg) and phosphate (P). After 21 days of remineralisation, scanning electron microscopy and energy-dispersive X-ray (EDX) assessments were performed, and the results were analysed using one-way analysis of variance., Results: EDX analysis showed that the ROCS medical remineralising gel had the lowest Ca/P ratio among the groups (P = .04). Compared with the control groups, the Remin Pro and ROCS medical remineralising gel treatments produced significantly higher Ca/P ratios (P = .014 and P = .025). These results were statistically significant, and P-value <.05 was accepted for statistical significance., Conclusions: The group treated with a fluoride-free, xylitol-containing ROCS medical remineralising gel had the lowest Ca/P ratio. Compared with the control groups, Remin Pro and ROCS remineralising gel appeared effective for repairing initial enamel lesions., (© 2021 John Wiley & Sons Ltd.)

The aim of this study was to research carbonic anhydrase (CA) VI one single-nucleotide polymorphism (SNP) and its potential association with dental-oral health status (dental caries, Plaque Index (PI) and Gingival Index (GI)) and salivary parameters (salivary buffering capacity, salivary flow rate (SFR)) in children. A total of 178 children were divided into two groups: non-carious (n = 70, 34 boys and 36 girls) and carious (n = 108, 47 boys and 61 girls). The clinical evaluations were performed according to the decayed, missing, and filled teeth (dmft/DMFT) index by a specialist. Clinical parameters including PI, GI, and simplified oral hygiene index (OHI-S) were recorded. Salivary pH (SpH) was measured using pH paper. Blood samples and unstimulated whole saliva were collected, and SFR was calculated. The CA VI rs2274327 polymorphism was determined by a LightSNiP assay on the realtime PCR system. The frequencies of rs2274327 were not significant between groups (p > 0.05). There was a positive correlation between OHI-S and SpH in the carious and non-carious groups (p < 0.05). There was no correlation among the SNPs' frequencies and OHI-S, PI, GI, SFR, and SpH (p > 0.05). CA VI SNP (rs2274327) had no statistically significant association with OHI-S, PI, GI, SFR, and SpH in the children.