1. Churg-Strauss syndrome with a clinical condition similar to IgG4-related kidney disease: a case report.
- Author
-
Ayuzawa N, Ubara Y, Keiichi S, Masayuki Y, Hasegawa E, Hiramatsu E, Hayami N, Suwabe T, Hoshino J, Sawa N, Kawabata M, Ohashi K, and Takaichi K
- Subjects
- Aged, Churg-Strauss Syndrome diagnosis, Female, Glomerulonephritis, Membranous complications, Glomerulonephritis, Membranous diagnosis, Glomerulonephritis, Membranous immunology, Humans, Immunoglobulin G blood, Kidney Diseases diagnosis, Nephritis, Interstitial complications, Nephritis, Interstitial diagnosis, Nephritis, Interstitial immunology, Churg-Strauss Syndrome complications, Churg-Strauss Syndrome immunology, Immunoglobulin G metabolism, Kidney Diseases complications, Kidney Diseases immunology
- Abstract
A 68-year-old Japanese woman with asthma of recent onset and a long history of membranous glomerulonephropathy (MN) was admitted because of multifocal pulmonary infiltrates, marked eosinophilia, mild renal dysfunction, a rash on her feet, and right median nerve paralysis. Although MPO- and PR3-ANCA were negative, skin biopsy demonstrated leukocytoclastic vasculitis and Churg-Strauss Syndrome (CSS) was diagnosed. She also had salivary gland swelling and a high serum IgG4 level. Renal biopsy revealed MN with eosinophil-rich tubulointerstitial nephropathy. Her symptoms resolved after the start of corticosteroid therapy. The present case shows that ANCA-negative CSS can have a clinical condition similar to IgG4-related kidney disease.
- Published
- 2012
- Full Text
- View/download PDF