1. Resected tumor seeding in stomach wall due to endoscopic ultrasonography-guided fine needle aspiration of pancreatic adenocarcinoma.
- Author
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Tomonari A, Katanuma A, Matsumori T, Yamazaki H, Sano I, Minami R, Sen-yo M, Ikarashi S, Kin T, Yane K, Takahashi K, Shinohara T, and Maguchi H
- Subjects
- Adenocarcinoma therapy, Aged, Antimetabolites, Antineoplastic therapeutic use, Biopsy, Chemotherapy, Adjuvant, Drug Combinations, Gastrectomy, Humans, Male, Neoplasm Staging, Oxonic Acid therapeutic use, Pancreatectomy, Pancreatic Neoplasms therapy, Stomach Neoplasms surgery, Tegafur therapeutic use, Time Factors, Tomography, X-Ray Computed, Treatment Outcome, Adenocarcinoma secondary, Endoscopic Ultrasound-Guided Fine Needle Aspiration adverse effects, Neoplasm Seeding, Pancreatic Neoplasms pathology, Stomach Neoplasms secondary
- Abstract
Endoscopic ultrasonography-guided fine needle aspiration (EUS-FNA) is a useful and relatively safe tool for the diagnosis and staging of pancreatic cancer. However, there have recently been several reports of tumor seeding after EUS-FNA of adenocarcinomas. A 78-year-old man was admitted to our hospital due to upper gastric pain. Examinations revealed a 20 mm mass in the pancreatic body, for which EUS-FNA was performed. The cytology of the lesion was adenocarcinoma, and the stage of the cancer was T3N0M0. The patient underwent surgery with curative intent, followed by adjuvant chemotherapy with S-1. An enlarging gastric submucosal tumor was found on gastroscopy at 28 mo after surgery accompanied by a rising level of CA19-9. Biopsy result was adenocarcinoma, consistent with a pancreatic primary tumor. Tumor seeding after EUS-FNA was strongly suspected. The patient underwent surgical resection of the gastric tumor with curative intent. The pathological result of the resected gastric specimen was adenocarcinoma with a perfectly matched mucin special stain result with the previously resected pancreatic cancer. This is the first case report of tumor seeding after EUS-FNA which was surgically resected and inspected pathologically.
- Published
- 2015
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