1. Abnormal prefrontal functional network in adult obstructive sleep apnea: A resting-state fNIRS study.
- Author
-
Mingming Z, Wenhong C, Xiaoying M, Yang J, Liu HH, Lingli S, Hongwu M, and Zhirong J
- Subjects
- Adult, Humans, Brain Mapping methods, Magnetic Resonance Imaging methods, Cognition, Sleep Apnea, Obstructive, Cognitive Dysfunction etiology
- Abstract
To assess prefrontal brain network abnormality in adults with obstructive sleep apnea (OSA), resting-state functional near infrared spectroscopy (rs-fNIRS) was used to evaluate 52 subjects, including 27 with OSA and 25 healthy controls (HC). The study found that patients with OSA had a decreased connection edge number, particularly in the connection between the right medial frontal cortex (MFG-R) and other right-hemisphere regions. Graph-based analysis also revealed that patients with OSA had a lower global efficiency, local efficiency, and clustering coefficient than the HC group. Additionally, the study found a significant positive correlation between the Montreal Cognitive Assessment (MoCA) score and both the connection edge number and the graph-based indicators in patients with OSA. These preliminary results suggest that prefrontal rs-fNIRS could be a useful tool for objectively and quantitatively assessing cognitive function impairment in patients with OSA., (© 2023 European Sleep Research Society.)
- Published
- 2024
- Full Text
- View/download PDF