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We present an automated procedure for the design of optimal actuation for flagellar magnetic microswimmers based on numerical optimization. Using this method, a magnetic actuation method is provided which allows these devices to swim significantly faster compared to the usual sinusoidal actuation. This leads to a novel swimming strategy which makes the swimmer perform a three-dimensional figure-eight trajectory. This shows that a faster propulsion is obtained when the swimmer is allowed to go out of plane. This approach is experimentally validated on a scaled-up flexible swimmer.

The inertialess fluid-structure interactions of active and passive inextensible filaments and slender-rods are ubiquitous in nature, from the dynamics of semi-flexible polymers and cytoskeletal filaments to cellular mechanics and flagella. The coupling between the geometry of deformation and the physical interaction governing the dynamics of bio-filaments is complex. Governing equations negotiate elastohydrodynamical interactions with non-holonomic constraints arising from the filament inextensibility. Such elastohydrodynamic systems are structurally convoluted, prone to numerical errors, thus requiring penalization methods and high-order spatio-temporal propagators. The asymptotic coarse-graining formulation presented here exploits the momentum balance in the asymptotic limit of small rod-like elements which are integrated semi-analytically. This greatly simplifies the elastohydrodynamic interactions and overcomes previous numerical instability. The resulting matricial system is straightforward and intuitive to implement, and allows for a fast and efficient computation, more than a hundred times faster than previous schemes. Only basic knowledge of systems of linear equations is required, and implementation achieved with any solver of choice. Generalizations for complex interaction of multiple rods, Brownian polymer dynamics, active filaments and non-local hydrodynamics are also straightforward. We demonstrate these in four examples commonly found in biological systems, including the dynamics of filaments and flagella. Three of these systems are novel in the literature. We additionally provide a Matlab code that can be used as a basis for further generalizations., (© 2018 The Author(s).)

In this paper we address the question of the optimal design for the Purcell three-link swimmer. More precisely, we investigate the best link length ratio which maximizes its displacement. The dynamics of the swimmer is expressed as an ordinary differential equation, using the resistive force theory. Among a set of optimal strategies of deformation (strokes), we provide an asymptotic estimate of the displacement for small deformations, from which we derive the optimal link ratio. Numerical simulations are in good agreement with this theoretical estimate and also cover larger amplitudes of deformation. Compared with the classical design of the Purcell swimmer, we observe a gain in displacement of roughly 60%.