1. Paper-based chemiresistor for detection of ultralow concentrations of protein.
- Author
-
Pozuelo M, Blondeau P, Novell M, Andrade FJ, Xavier Rius F, and Riu J
- Subjects
- Biosensing Techniques economics, Equipment Design, Humans, Limit of Detection, Transducers, Biosensing Techniques instrumentation, Immunoglobulin G analysis, Nanotubes, Carbon chemistry, Paper
- Abstract
A new paper-based chemiresistor composed of a network of single-wall carbon nanotubes (SWCNTs) and anti-human immunoglobulin G (anti-HIgG) is reported herein. SWCNTs act as outstanding transducers because they provide high sensitivity in terms of resistance changes due to immunoreaction. As a result, the resistance-based biosensor reaches concentration detection as low as picomolar. The resulting paper-based biosensor is sensitive, selective and employs low-cost substrate and simple manufacturing stages. Since chemiresistors require low-power equipment and are able to detect low concentrations with inexpensive materials, the present approach may pave the way for the development of resistive biosensors at very low-cost with high performances., (Copyright © 2013 Elsevier B.V. All rights reserved.)
- Published
- 2013
- Full Text
- View/download PDF