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Retinal blood vessel segmentation is a valuable tool for clinicians to diagnose conditions such as atherosclerosis, glaucoma, and age-related macular degeneration. This paper presents a new framework for segmenting blood vessels in retinal images. The framework has two stages: a multi-layer preprocessing stage and a subsequent segmentation stage employing a U-Net with a multi-residual attention block. The multi-layer preprocessing stage has three steps. The first step is noise reduction, employing a U-shaped convolutional neural network with matrix factorization (CNN with MF) and detailed U-shaped U-Net (D_U-Net) to minimize image noise, culminating in the selection of the most suitable image based on the PSNR and SSIM values. The second step is dynamic data imputation, utilizing multiple models for the purpose of filling in missing data. The third step is data augmentation through the utilization of a latent diffusion model (LDM) to expand the training dataset size. The second stage of the framework is segmentation, where the U-Nets with a multi-residual attention block are used to segment the retinal images after they have been preprocessed and noise has been removed. The experiments show that the framework is effective at segmenting retinal blood vessels. It achieved Dice scores of 95.32, accuracy of 93.56, precision of 95.68, and recall of 95.45. It also achieved efficient results in removing noise using CNN with matrix factorization (MF) and D-U-NET according to values of PSNR and SSIM for (0.1, 0.25, 0.5, and 0.75) levels of noise. The LDM achieved an inception score of 13.6 and an FID of 46.2 in the augmentation step.

One of the most prevalent diseases affecting women in recent years is breast cancer. Early breast cancer detection can help in the treatment, lower the infection risk, and worsen the results. This paper presents a hybrid approach for augmentation and segmenting breast cancer. The framework contains two main stages: augmentation and segmentation of ultrasound images. The augmentation of the ultrasounds is applied using generative adversarial networks (GAN) with nonlinear identity block, label smoothing, and a new loss function. The segmentation of the ultrasounds applied a modified U-Net 3+. The hybrid approach achieves efficient results in the segmentation and augmentation steps compared with the other available methods for the same task. The modified version of the GAN with the nonlinear identity block overcomes different types of modified GAN in the ultrasound augmentation process, such as speckle GAN, UltraGAN, and deep convolutional GAN. The modified U-Net 3+ also overcomes the different architectures of U-Nets in the segmentation process. The GAN with nonlinear identity blocks achieved an inception score of 14.32 and a Fréchet inception distance of 41.86 in the augmenting process. The GAN with identity achieves a smaller value in Fréchet inception distance (FID) and a bigger value in inception score; these results prove the model's efficiency compared with other versions of GAN in the augmentation process. The modified U-Net 3+ architecture achieved a Dice Score of 95.49% and an Accuracy of 95.67%.

Because of the large variabilities in brain tumors, automating segmentation remains a difficult task. We propose an automated method to segment brain tumors by integrating the deep capsule network (CapsNet) and the latent-dynamic condition random field (LDCRF). The method consists of three main processes to segment the brain tumor-pre-processing, segmentation, and post-processing. In pre-processing, the N4ITK process involves correcting each MR image's bias field before normalizing the intensity. After that, image patches are used to train CapsNet during the segmentation process. Then, with the CapsNet parameters determined, we employ image slices from an axial view to learn the LDCRF-CapsNet. Finally, we use a simple thresholding method to correct the labels of some pixels and remove small 3D-connected regions from the segmentation outcomes. On the BRATS 2015 and BRATS 2021 datasets, we trained and evaluated our method and discovered that it outperforms and can compete with state-of-the-art methods in comparable conditions.