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284 results on '"Carell, T."'

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1. Step-by-Step Towards Biological Homochirality - from Prebiotic Randomness To Perfect Asymmetry.

2. Hypoxia-dependent recruitment of error-prone DNA polymerases to genome replication.

3. A Phosphotriester-Masked Dideoxy-cGAMP Derivative as a Cell-Permeable STING Agonist.

4. Robust Bisulfite-Free Single-Molecule Real-Time Sequencing of Methyldeoxycytidine Based on a Novel hpTet3 Enzyme.

5. Depletion of m 6 A-RNA in Escherichia coli reduces the infectious potential of T5 bacteriophage.

6. Generation of densely labeled oligonucleotides for the detection of small genomic elements.

7. Gradual evolution of a homo-l-peptide world on homo-d-configured RNA and DNA.

8. Lysosomal endonuclease RNase T2 and PLD exonucleases cooperatively generate RNA ligands for TLR7 activation.

9. Efficient Tandem Copper-Catalyzed Click Synthesis of Multisugar-Modified Oligonucleotides.

10. RNA-Templated Peptide Bond Formation Promotes L-Homochirality.

11. Orthogonal End Labelling of Oligonucleotides through Dual Incorporation of Click-Reactive NTP Analogues.

12. Experience with German Research Consortia in the Field of Chemical Biology of Native Nucleic Acid Modifications.

13. Synthesis and Structure Elucidation of Glutamyl-Queuosine.

14. 3'-tRF-Cys GCA overexpression in HEK-293 cells alters the global expression profile and modulates cellular processes and pathways.

15. Human TRMT2A methylates tRNA and contributes to translation fidelity.

16. Depletion of pyruvate kinase (PK) activity causes glycolytic intermediate imbalances and reveals a PK-TXNIP regulatory axis.

17. Loading of Amino Acids onto RNA in a Putative RNA-Peptide World.

18. Third-Generation Sequencing of Epigenetic DNA.

19. STING agonism turns human T cells into interferon-producing cells but impedes their functionality.

20. Divergent Synthesis of Ultrabright and Dendritic Xanthenes for Enhanced Click-Chemistry-Based Bioimaging.

22. Isoxazole Nucleosides as Building Blocks for a Plausible Proto-RNA.

23. Click Chemistry Enables Rapid Amplification of Full-Length Reverse Transcripts for Long-Read Third Generation Sequencing.

24. Queuosine salvage in fission yeast by Qng1-mediated hydrolysis to queuine.

25. Novel Poxin Stable cGAMP-Derivatives Are Remarkable STING Agonists.

26. Suppression of SARS-CoV-2 Replication with Stabilized and Click-Chemistry Modified siRNAs.

27. Isoform-specific and ubiquitination dependent recruitment of Tet1 to replicating heterochromatin modulates methylcytosine oxidation.

28. Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G 4 C 2 ) n expression in C9orf72 ALS/FTD.

29. 1 H NMR Chemical Exchange Techniques Reveal Local and Global Effects of Oxidized Cytosine Derivatives.

30. Epigenetic Anti-Cancer Treatment With a Stabilized Carbocyclic Decitabine Analogue.

31. A prebiotically plausible scenario of an RNA-peptide world.

32. Chemical Synthesis of the Fluorescent, Cyclic Dinucleotides c th GAMP.

33. tRNA modification profiles in obligate and moderate thermophilic bacilli.

34. Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death.

35. Synthesis and structure elucidation of the human tRNA nucleoside mannosyl-queuosine.

36. Unified Description of Ultrafast Excited State Decay Processes in Epigenetic Deoxycytidine Derivatives.

37. Intragenomic Decarboxylation of 5-Carboxy-2'-deoxycytidine.

38. Direct and Base Excision Repair-Mediated Regulation of a GC-Rich cis -Element in Response to 5-Formylcytosine and 5-Carboxycytosine.

39. Biomimetic Iron Complex Achieves TET Enzyme Reactivity*.

40. Comparative Nucleosomal Reactivity of 5-Formyl-Uridine and 5-Formyl-Cytidine.

41. Deformylation of 5-Formylcytidine in Different Cell Types.

42. Intercellular cGAMP transmission induces innate immune activation and tissue inflammation in Trex1 deficiency.

43. Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons.

44. TENT4A Non-Canonical Poly(A) Polymerase Regulates DNA-Damage Tolerance via Multiple Pathways That Are Mutated in Endometrial Cancer.

45. 5-Hydroxymethyl-, 5-Formyl- and 5-Carboxydeoxycytidines as Oxidative Lesions and Epigenetic Marks.

46. François Diederich (1952-2020): 40 Years of Organic Chemistry.

47. Targeting the nucleotide salvage factor DNPH1 sensitizes BRCA -deficient cells to PARP inhibitors.

48. Quantification of DNA Methylation and Its Oxidized Derivatives Using LC-MS.

49. The cGMP-Dependent Protein Kinase 2 Contributes to Cone Photoreceptor Degeneration in the Cnga3 -Deficient Mouse Model of Achromatopsia.

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