1. The different adsorption-degradation behaviors of SARS-CoV-2 by bioactive chemicals in wastewater: The suppression kinetics and their implications for wastewater-based epidemiology.
- Author
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Bayati M, Hsieh HY, Hsu SY, Qasim S, Li C, Belenchia A, Klutts J, Zemmer SA, Sibley K, Reynolds M, Semkiw E, Johnson HY, Lyddon T, Wieberg CG, Wenzel J, Johnson MC, and Lin CH
- Subjects
- Adsorption, Surface-Active Agents, Pandemics, Kinetics, Humans, Waste Disposal, Fluid methods, Wastewater-Based Epidemiological Monitoring, Water Pollutants, Chemical analysis, Alkanesulfonic Acids, Wastewater virology, Wastewater chemistry, SARS-CoV-2, COVID-19 epidemiology
- Abstract
Wastewater-Based Epidemiology (WBE) is widely used to monitor the progression of SARS-CoV-2 pandemic. While there is a clear correlation between the number of COVID patients in a sewershed and the viral load in the wastewater, there is notable variability across different treatment plants. In particular, some facilities consistently exhibit higher viral content per diagnosed patient, implying a potential underestimation of the number of COVID patients, while others show a low viral load per diagnosed case, indicating potential attenuation of genetic material from the sewershed. In this study, we investigated the impact of nonylphenol ethoxylate (NPHE), linear alkylbenzene sulfonic acid (LABS), bisoctyl dimethyl ammonium chloride (BDAC), and didecyldimethylammonium chloride (DDAC), the surfactants that have been commonly used as detergents, emulsifiers, wetting agents on the stability of SARS-CoV-2 in wastewater. The results showed multiple and dynamic mechanisms, including degradation and desorption, can occur simultaneously during the interaction between SARS-CoV-2 and different chemicals depending on the physicochemical properties of each chemical. Through the elucidation of the dynamic interactions, the findings from this study could help the state health organizations and scientific community to optimize the SARS-CoV-2 wastewater-based epidemiology strategies., Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Chung-Ho Lin reports financial support was provided by The Centers for Disease Control and prevention and the National Institute on Drug Abuse of the National Institutes of Health. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.)
- Published
- 2024
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