Search

There is a pressing demand for the development of novel birefringent crystals tailored for compact optical components, especially for crystals exhibiting large birefringence across a range of temperatures. This has commonly been achieved by introducing various deformable groups with high polarizability anisotropy. In this study, we combined both rigid and deformable groups to synthesise a new birefringent crystal, Al 2 Te 2 MoO 10 , which demonstrates an exceptional birefringence value of 0.29@550 nm at room temperature. Not only is this higher birefringence than that of commercial crystals, but Al 2 Te 2 MoO 10 exhibits excellent birefringence stability over a wide temperature range, from 123 to 503 K. In addition, the first-principles theory calculations and structural analyses suggest that although the rigid AlO 6 groups do not make much contribution to the prominent birefringence, they nonetheless played a role in maintaining the structural anisotropy at elevated temperatures. Based on these findings, this paper proposes a novel structural design strategy to complement conventional approaches for developing optimal birefringent crystals under various environmental conditions., (Copyright © 2024 Science China Press. Published by Elsevier B.V. All rights reserved.)

Lung cancer is an exceedingly malignant tumor reported as having the highest morbidity and mortality of any cancer worldwide, thus posing a great threat to global health. Despite the growing demand for precision medicine, current methods for early clinical detection, treatment and prognosis monitoring in lung cancer are hampered by certain bottlenecks. Studies have found that during the formation and development of a tumor, molecular substances carrying tumor-related genetic information can be released into body fluids. Liquid biopsy (LB), a method for detecting these tumor-related markers in body fluids, maybe a way to make progress in these bottlenecks. In recent years, LB technology has undergone rapid advancements. Therefore, this review will provide information on technical updates to LB and its potential clinical applications, evaluate its effectiveness for specific applications, discuss the existing limitations of LB, and present a look forward to possible future clinical applications. Specifically, this paper will introduce technical updates from the prospectives of engineering breakthroughs in the detection of membrane-based LB biomarkers and other improvements in sequencing technology. Additionally, it will summarize the latest applications of liquid biopsy for the early detection, diagnosis, treatment, and prognosis of lung cancer. We will present the interconnectedness of clinical and laboratory issues and the interplay of technology and application in LB today., (Copyright © 2024 Science China Press. Published by Elsevier B.V. All rights reserved.)

Aerosols greatly influence precipitation characteristics, thereby impacting the regional climate and human life. As an indispensable factor for cloud formation and a critical radiation budget regulator, aerosols can affect precipitation intensity, frequency, geographical distribution, area, and time. However, discrepancies exist among current studies due to aerosol properties, precipitation types, the vertical location of aerosols and meteorological conditions. The development of technology has driven advances in current research, but understanding the aerosol effects on precipitation remain complex and challenging. This paper revolves around the following topics from the two perspectives of Aerosol-Radiation Interaction (ARI) and Aerosol-Cloud Interaction (ACI): (1) the influence of different vertical locations of absorbing/scattering aerosols on the atmospheric thermal structure; (2) the fundamental theories of ARI reducing surface wind speed, redistributing water vapour and energy, and then modulating precipitation intensity; (3) different aerosol types (absorbing versus scattering) and aerosol concentrations causing different precipitation diurnal and weekly variations; (4) microphysical processes (cloud water competition, invigoration effect, and evaporation cooling) and observational evidence of different effects of aerosols on precipitation intensity, including enhancing, inhibiting, and transitional effects from enhancement to suppression; and (5) how meteorology, water vapor and dynamics influencing the effect of ACI and ARI on precipitation. In addition, this review lists the existing issues and future research directions for attaining a more comprehensive understanding of aerosol effects on precipitation. Overall, this review advances our understanding of aerosol effects on precipitation and could guide the improvement of weather and climate models to predict complex aerosol-precipitation interactions more accurately., (Copyright © 2024 Science China Press. Published by Elsevier B.V. All rights reserved.)

The emergence of exotic quantum phenomena in frustrated magnets is rapidly driving the development of quantum many-body physics, raising fundamental questions on the nature of quantum phase transitions. Here we unveil the behaviour of emergent symmetry involving two extraordinarily representative phenomena, i.e., the deconfined quantum critical point (DQCP) and the quantum spin liquid (QSL) state. Via large-scale tensor network simulations, we study a spatially anisotropic spin-1/2 square-lattice frustrated antiferromagnetic (AFM) model, namely the J 1x -J 1y -J 2 model, which contains anisotropic nearest-neighbor couplings J 1x ,J 1y and the next nearest neighbor coupling J 2 . For small J 1y /J 1x , by tuning J 2 , a direct continuous transition between the AFM and valence bond solid phase is observed. With growing J 1y /J 1x , a gapless QSL phase gradually emerges between the AFM and VBS phases. We observe an emergent O(4) symmetry along the AFM-VBS transition line, which is consistent with the prediction of DQCP theory. Most surprisingly, we find that such an emergent O(4) symmetry holds for the whole QSL-VBS transition line as well. These findings reveal the intrinsic relationship between the QSL and DQCP from categorical symmetry point of view, and strongly constrain the quantum field theory description of the QSL phase. The phase diagram and critical exponents presented in this paper are of direct relevance to future experiments on frustrated magnets and cold atom systems., Competing Interests: Conflict of interest The authors declare that they have no conflict of interest., (Copyright © 2023 Science China Press. Published by Elsevier B.V. All rights reserved.)