88 results
Search Results
2. Contribution of the scientific field of Physical and Rehabilitation Medicine to improvements in health-related rehabilitation at all levels of the healthcare system: A discussion paper.
- Author
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Nugraha B and Gutenbrunner C
- Subjects
- Humans, Delivery of Health Care organization & administration, Physical and Rehabilitation Medicine organization & administration
- Abstract
Rehabilitation is an important health strategy that should be implemented at all levels of the healthcare system and at all levels of care. Scientific evidence is vital to strengthen rehabilitation; therefore, research in the scientific field of Physical and Rehabilitation Medicine (PRM) should be implemented and linked to all levels of the healthcare system. PRM research can be categorized into 5 areas: (i) biosciences in rehabilitation; (ii) biomedical rehabilitation sciences and engineering; (iii) clinical PRM sciences; (iv) integrative rehabilitation sciences; and (v) human function-ing sciences. At the level of the healthcare system, rehabilitation can be divided into micro-, meso- and macro-levels. This paper discusses the contribution of the five above research areas to health-related rehabilitation at the different levels of the healthcare system. The contribution of PRM research can have synergistic value and facilitate improvements and implementation of scientific evidence in rehabilitation at all levels of healthcare. From a broader perspective, improved understanding of the contribution of each area of the scientific field of PRM and the priorities for the healthcare system that are set by relevant stakeholders will contribute to the advancement and rapid attainment of overall goals.
- Published
- 2021
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3. How registry data can improve outcomes from joint replacement - a seminal paper.
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Tucker K
- Subjects
- Registries, Arthroplasty, Replacement
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- 2020
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4. The challenges of describing rehabilitation services: A discussion paper.
- Author
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Røe C, Kirkevold M, Andelic N, Soberg HL, Sveen U, Bautz-Holter E, Jahnsen R, van Walsem MR, Kildal Bragstad L, Gabrielsen Hjelle E, Klevberg G, Oretorp P, Habberstad A, Hagfors J, Væhle R, Engen G, and Gutenbrunner C
- Subjects
- Female, Humans, Male, Brain Injuries rehabilitation, Health Services trends
- Abstract
To apply the Classification of Service Organization in Rehabilitation (ICSO-R) classification of services to different target groups, include the user perspective, identify missing categories, and propose standardized descriptors for the categories from a Norwegian perspective. Expert-based consensus conferences with user involvement. Health professionals, stakeholders and users. Participants were divided into 5 panels, which applied the ICSO-R to describe the habilitation and rehabilitation services provided to children with cerebral palsy and people with Huntington's disease, acquired brain injuries (traumatic brain injuries and stroke) and painful musculoskeletal conditions. Based on the Problem/Population, Intervention, Comparison, Outcome (PICO) framework, the services were described according to the ICSO-R. Missing categories were identified. The ICSO-R was found to be feasible and applicable for describing a variety of services provided to different target groups in Norway, but the user perspective was lacking, categories were missing, and a need for standardized description of the categories was identified. The present work supports the need to produce an updated version of the ICSO-R and to encourage national and international discussion of the framework. The ICSO-R has the potential to become a tool for the standardized assessment of rehabilitation services. For such purposes, more standardized descriptions of subcategories are necessary.
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- 2018
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5. Comment to letter to the editor Re: ISPRM Discussion Paper: Proposing Dimensions for an International Classification System for Service Organisation in Health-related Rehabilitation (ICSO-R).
- Author
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Gutenbrunner C
- Subjects
- World Health Organization, Physical and Rehabilitation Medicine standards
- Abstract
is missing.
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- 2016
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6. Re: ISPRM discussion paper: Proposing dimensions for an international classification sytem for service organization in health-related rehabilitation.
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Van de Velde D and Vanderstraeten G
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- Humans, Health Services classification, International Agencies classification, World Health Organization organization & administration
- Published
- 2016
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7. ISPRM discussion paper: proposing dimensions for an International Classification System for Service Organization in Health-related Rehabilitation.
- Author
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Gutenbrunner C, Bickenbach J, Kiekens C, Meyer T, Skempes D, Nugraha B, Bethge M, and Stucki G
- Subjects
- Humans, Health Services classification, International Agencies classification, World Health Organization organization & administration
- Abstract
Objective: Rehabilitation is 1 of 4 main health strategies. The World Report on Disability identifies deficits in rehabilitation care for people with disabilities as an important barrier to full inclusion in society or to achieve optimal functioning. In order to overcome such deficits, to close gaps in national and/or regional rehabilitation systems, and to develop appropriate rehabilitation services, it is crucial to define uniform criteria and a widely accepted language to describe and classify rehabilitation services. The aim of this paper was therefore to develop a list of dimensions and categories to describe the organization of health-related rehabilitation services., Methods: The classification is based on a series of expert workshops including members of the International and European Society of Physical Medicine and Rehabilitation., Results: The proposed classification has 2 levels (dimensions and categories). The upper level distinguishes 3 dimensions: the service provider (with 9 categories), the funding of the service (with 3 categories), and the service delivery (8 subcategories). A further specification of the categories in a 3-level classification (including value sets) is needed., Conclusion: This paper is an intermediate step towards development of a classification system with distinct categories and dimensions.
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- 2015
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8. A bibliometric analysis of the 50 most cited papers in cleft lip and palate.
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Mahon NA and Joyce CW
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- Humans, Journalism, Medical, Publishing, Bibliometrics, Cleft Lip, Cleft Palate
- Abstract
Citation analysis is an established bibliometric method which catalogues papers according to the number of times they have been referenced. It is believed that the total number of citations an article receives reflects its importance among its peers. Never before has a bibliometric analysis been performed in the area of Cleft Lip and Palate. Our citation analysis creates a comprehensive list of the 50 most influential papers in this field. Journals specializing in Cleft Palate, Craniofacial, Plastic Surgery, Maxillofacial Surgery, Aesthetics and Radiology were searched to establish which articles most enriched the specialty over the past 70 years. The results show an interesting collection of papers which reveal developing trends in surgical techniques. These landmark papers mould and influence management and decision-making today.
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- 2015
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9. Classic Kaposi sarcoma: Diagnostics, treatment modalities, and genetic implications - A review of the literature.
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Batash R, Crimí A, Kassem R, Asali M, Ostfeld I, Biz C, Ruggieri P, and Schaffer M
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- Humans, Herpesvirus 8, Human genetics, Herpesvirus 8, Human isolation & purification, Mutation, Sarcoma, Kaposi therapy, Sarcoma, Kaposi diagnosis, Sarcoma, Kaposi genetics, Sarcoma, Kaposi pathology
- Abstract
Background and Purpose: Classic Kaposi sarcoma (CKS) is a rare vascular disease mainly found in populations of Mediterranean origin. The pathogenesis involves Human Herpes Virus 8 (HHV8) and genetic mutations such as SNP309 in the MDM2 gene. The recently discovered BPTF mutation in cells of CKS patients demonstrated higher latency-associated nuclear antigen (LANA) staining and altered vital transcriptomics, implicating a potential role in tumorigenesis. This review explores the genetic underpinnings and treatments for CKS., Material and Methods: A comprehensive literature search was conducted from 2004 to 2024, yielding 70 relevant papers. Ongoing clinical trials investigating novel treatments such as talimogene and abemaciclib were included in the search and presented in the results., Results: Clinical diagnosis and treatment can be challenging as the number of studies on CKS and treatment modalities is limited. Treatment strategies vary by disease stage, with local therapies like surgical intervention and radiation therapy recommended for early stages, while systemic therapies are considered in cases of systemic disease., Interpretation: While advancements in CKS treatment offer hope, further studies on immunotherapy are warranted to broaden the therapeutic options, such as anti-bromodomain or BPTF-targeted therapy.
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- 2024
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10. Do proprioceptive training strategies with dual-task exercises positively influence gait parameters in chronic stroke? A systematic review.
- Author
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Vecchio M, Chiaramonte R, De Sire A, Buccheri E, Finocchiaro P, Scaturro D, Letizia Mauro G, and Cioni M
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- Humans, Gait physiology, Stroke physiopathology, Chronic Disease, Gait Disorders, Neurologic rehabilitation, Gait Disorders, Neurologic physiopathology, Gait Disorders, Neurologic etiology, Stroke Rehabilitation methods, Exercise Therapy methods, Proprioception physiology
- Abstract
Objective: This study aims to assess the impact of proprioceptive training strategies with dual-task exercises on gait in people with chronic stroke., Study Design: Systematic review., Patients: Chronic stroke., Methods: Searches were conducted in accordance with PRISMA guidelines and PICOS criteria. PubMed, Web of Science, and Scopus databases were systematically searched from November 2020 to February 2022, for eligible clinical trials. Two independent reviewers thoroughly screened potential articles for relevance and assessed the methodology quality. In accordance with the GRADE, PICOS criteria, and Cochrane risk of bias tools, the authors included articles concerning the effectiveness of dual-task in proprioceptive training on gait parameters in people with chronic stroke., Results: Of 3075 identified studies, 11 articles met the inclusion criteria: 7 were randomized clinical trials, 1 was not randomized, and 3 were observational studies. The overall quality of evidence, assessed using the GRADE framework, was high, indicating a high level of confidence in the systematic review's findings. The papers involved 393 stroke patients; 241 underwent dual-task in proprioceptive training, with 152 participants in other stroke rehabilitation; within the dual-task group, 71 engaged in cognitive tasks, and 170 participated in motor tasks. dual-task in proprioceptive training improved gait speed, cadence, stride time, stride length, and step length. The best effects were observed with training 3 times a week for 4 weeks, with each session lasting 30 minutes, on speed, cadence, stride length, and step length., Conclusion: Current evidence suggests that proprioceptive training strategies with dual-task exercises improved walking abilities in people with chronic stroke. Specifically, it enhanced gait speed, a key indicator of clinical severity.
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- 2024
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11. Guideline for RSA and CT-RSA implant migration measurements: an update of standardizations and recommendations.
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Kaptein BL, Pijls B, Koster L, Kärrholm J, Hull M, Niesen A, Heesterbeek P, Callary S, Teeter M, Gascoyne T, Röhrl SM, Flivik G, Bragonzoni L, Laende E, Sandberg O, Solomon LB, Nelissen R, and Stilling M
- Subjects
- Humans, Prosthesis Failure, Practice Guidelines as Topic, Radiostereometric Analysis, Tomography, X-Ray Computed
- Abstract
Opening remarks: These guidelines are the result of discussions within a diverse group of RSA researchers. They were approved in December 2023 by the board and selected members of the International Radiostereometry Society to update the guidelines by Valstar et al. [1]. By adhering to these guidelines, RSA studies will become more transparent and consistent in execution, presentation, reporting, and interpretation. Both authors and reviewers of scientific papers using RSA may use these guidelines, summarized in the Checklist, as a reference. Deviations from these guidelines should have the underlying rationale stated.
- Published
- 2024
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12. Occupational and Physiotherapy modalities used to support interdisciplinary rehabilitation after concussion: A Scoping Review.
- Author
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Marwaa MN, Klakk Egebæk H, and Dalgaard Guldager J
- Subjects
- Adult, Humans, Adaptation, Psychological, Exercise, Patient Discharge, Physical Therapy Modalities, Brain Concussion
- Abstract
Objective: To identify and describe occupational and physiotherapy rehabilitation modalities used to support an interdisciplinary rehabilitation in adults (aged 16 + years) with concussion., Methods: A scoping review methodology was used. Included studies were categorized according to Wade's elements of rehabilitation and the Danish White Paper definition of rehabilitation., Results: Ten studies were included in this review, addressing: "assessment" (n = 9), "goal-setting" (n = 4), "training" (n = 10), and "social participation and discharge support" (n = 4). Interventions were delivered mainly by physiotherapists or an interdisciplinary team. In two studies occupational therapists were part of the interdisciplinary team. Randomized controlled trials more often addressed several of the rehabilitation elements using interdisciplinary intervention delivery. No studies specifically aimed their intervention at patients with acute or subacute concussion., Conclusion: The therapeutic modalities identified were: (i) manual and sensory motor interventions; (ii) physical exercises; and (iii) management of, or coping with, symptoms. More research is needed on how to better support social participation and discharge or return to work in the rehabilitation process. In addition, interventions delivered in the acute phases of concussion need further exploration.
- Published
- 2023
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13. Is conservative management of partial zone II flexor tendon laceration possible? A systematic literature review and meta-analysis.
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Mo YW, Ryu DH, Cho GY, and Hong JW
- Subjects
- Humans, Conservative Treatment, Cross-Sectional Studies, Tendons surgery, Lacerations surgery, Tendon Injuries surgery
- Abstract
Background: There is still no consensus on managing zone II level partial flexor tendon lacerations, and the management of zone II partial flexor tendon injuries is controversial. No reliable large cohort studies or metaanalysis papers on partial flexor tendon laceration management are available in PubMed or Embase. Methods: We searched PubMed, Embase, Cochrane Library, Insight, Scopus, and Web of Science databases for primary research articles investigating outcomes of patients with partial flexor tendon injuries. The initial search was limited to human studies that were published from 1970-2021 and indexed as randomized controlled or clinical trials or observational, cross-sectional, or cohort studies. We used statistical package R version 4.1.2 for this meta-analysis. Results: The Standardised mean difference (SMD) of the common effects model was 2.020 (95% CI; 1.583-2.457; P < 0.0001), indicating that the results of conservative treatment without surgical intervention are similar to surgical intervention or better in some articles. The SMD of the random effect model was 7.093 (95% CI; 1.090-13.096; P < 0.0206), indicating the same result. Higgins' I2 value was 97.6%, indicating serious heterogeneity. Conclusions: In this first meta-analysis on flexor zone II conservative treatment, five papers with publication bias were analyzed. It is meaningful to verify the result of conservative treatment statistically. Even though this is a heterogeneous paper, conservative treatment seems to have a lot of benefits for the patient, including offering a fairly solid longterm prognosis with very few complications.
- Published
- 2023
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14. The European Bone and Joint Infection Society definition of periprosthetic joint infection is meaningful in clinical practice: a multicentric validation study with comparison with previous definitions.
- Author
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Sousa R, Ribau A, Alfaro P, Burch MA, Ploegmakers J, McNally M, Clauss M, Wouthuyzen-Bakker M, and Soriano A
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- Humans, Retrospective Studies, Predictive Value of Tests, Reoperation adverse effects, Sensitivity and Specificity, Synovial Fluid, Biomarkers, Arthroplasty, Replacement, Hip adverse effects, Prosthesis-Related Infections surgery, Arthroplasty, Replacement, Knee adverse effects, Arthritis, Infectious diagnosis, Arthritis, Infectious etiology, Arthritis, Infectious surgery
- Abstract
Background and Purpose: A new periprosthetic joint infection (PJI) definition has recently been proposed by the European Bone and Joint Infection Society (EBJIS). The goals of this paper are to evaluate its diagnostic accuracy and compare it with previous definitions and to assess its accuracy in preoperative diagnosis., Patients and Methods: We retrospectively evaluated a multicenter cohort of consecutive revision total hip and knee arthroplasties. Cases with minimum required diagnostic workup were classified according to EBJIS, 2018 International Consensus Meeting (ICM 2018), Infectious Diseases Society of America (IDSA), and modified 2013 Musculoskeletal Infection Society (MSIS) definitions. 2 years' minimum follow-up was required to assess clinical outcome., Results: Of the 472 cases included, PJI was diagnosed in 195 (41%) cases using EBJIS; 188 (40%) cases using IDSA; 172 (36%) using ICM 2018; and 145 (31%) cases using MSIS. EBJIS defined fewer cases as intermediate (5% vs. 9%; p = 0.01) compared with ICM 2018. Specificity was determined by comparing risk of subsequent PJI after revision surgery. Infected cases were associated with higher risk of subsequent PJI in every definition. Cases classified as likely/confirmed infections using EBJIS among those classified as not infected in other definitions showed a significantly higher risk of subsequent PJI compared with concordant non-infected cases using MSIS (RR = 3, 95% CI 1-6), but not using ICM 2018 (RR = 2, CI 1-6) or IDSA (RR = 2, CI 1-5). EBJIS showed the highest agreement between pre-operative and definitive classification (k = 0.9, CI 0.8-0.9) and was better at ruling out PJI with an infection unlikely result (sensitivity 89% [84-93], negative predictive value 90% [85-93])., Conclusion: The newly proposed EBJIS definition emerged as the most sensitive of all major definitions. Cases classified as PJI according to the EBJIS criteria and not by other definitions seem to have increased risk of subsequent PJI compared with concordant non-infected cases. EBJIS classification is accurate in ruling out infection preoperatively.
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- 2023
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15. Interpretation of composite endpoints in urology: an analysis of citation quality.
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Jacobsen FM, Kvorning Ternov K, Nolsøe AB, Østergren PB, Fode M, Sønksen J, and Jensen CFS
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- Humans, Urology
- Abstract
Objective: To investigate how urological studies using composite endpoints as the primary outcome were cited., Materials and Methods: In this quality analysis of citations, three randomized clinical trials each investigating oncological and non-oncological urology were selected for citation analysis based on pre-defined criteria. In total, 531 papers citing the selected studies were reviewed; citations were evaluated based on whether they correctly referred to the composite endpoint and if singleton endpoints were defined and/or discussed., Results: Among the citations, 223/531 (42%) referred to the composite endpoint, of which 217/223 (97.3%) correctly cited the composite endpoint. However, only 91/217 (41.9%) defined and/or discussed the singleton endpoints of the composite endpoint. The lack of a validated instrument for citation analysis was a limitation of this study. Meanwhile, the main strength is the large number of individually analyzed citations., Conclusions: The composite endpoints of urological randomized clinical trials are generally cited without referring to the composite endpoint; when cited, the composite endpoints are described correctly. However, in most cases, without defining or discussing the singleton endpoints.
- Published
- 2022
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16. Effect of cold and heat therapies on pain relief in patients with delayed onset muscle soreness: A network meta-analysis.
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Wang Y, Lu H, Li S, Zhang Y, Yan F, Huang Y, Chen X, Yang A, Han L, and Ma Y
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- Cryotherapy, Humans, Network Meta-Analysis, Pain Management, Hot Temperature, Myalgia etiology, Myalgia therapy
- Abstract
Objective: To comprehensively compare the effectiveness of cold and heat therapies for delayed onset muscle soreness using network meta-analysis., Methods: Eight Chinese and English databases were searched from date of establishment of the database to 31 May 2021. Cochrane risk-of-bias tool was used to analyse the included randomized controlled trials. Potential papers were screened for eligibility, and data were extracted by 2 independent researchers., Results: A total of 59 studies involving 1,367 patients were eligible for this study. Ten interventions were examined: contrast water therapy, phase change material, the novel modality of cryotherapy, cold-water immersion, hot/warm-water immersion, cold pack, hot pack, ice massage, ultrasound, and passive recovery. Network meta-analysis results showed that: (i) within 24 h after exercise, hot pack was the most effective for pain relief, followed by contrast water therapy; (ii) within 48 h, the ranking was hot pack, followed by the novel modality of cryotherapy; and (iii) over 48 h post-exercise, the effect of the novel modality of cryotherapy ranked first., Conclusion: Due to the limited quality of the included studies, further well-designed research is needed to draw firm conclusions about the effectiveness of cold and heat therapies for delayed onset muscle soreness.
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- 2022
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17. Efficacy of repetitive transcranial magnetic stimulation for improving lower limb function in individuals with neurological disorders: A systematic review and meta-analysis of randomized sham-controlled trials.
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Krogh S, Jønsson AB, Aagaard P, and Kasch H
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- Humans, Lower Extremity, Randomized Controlled Trials as Topic, Recovery of Function, Transcranial Magnetic Stimulation, Gait Disorders, Neurologic, Stroke Rehabilitation
- Abstract
Objective: To determine the efficacy of repetitive transcranial magnetic stimulation vs sham stimulation on improving lower-limb functional outcomes in individuals with neurological disorders., Data Sources: PubMed, CINAHL, Embase and Scopus databases were searched from inception to 31 March 2020 to identify papers (n = 1,198). Two researchers independently reviewed studies for eligibility. Randomized clinical trials with parallel-group design, involving individuals with neurological disorders, including lower-limb functional outcome measures and published in scientific peer-reviewed journals were included., Data Extraction: Two researchers independently screened eligible papers (n = 27) for study design, clinical population characteristics, stimulation protocol and relevant outcome measures, and assessed study quality., Data Synthesis: Studies presented a moderate risk of selection, attrition and reporting bias. An overall effect of repetitive transcranial magnetic stimulation was found for outcomes: gait (effect size [95% confidence interval; 95% CI]: 0.51 [0.29; 0.74], p = 0.003) and muscle strength (0.99 [0.40; 1.58], p = 0.001) and disorders: stroke (0.20 [0.00; 0.39], p = 0.05), Parkinson's disease (1.01 [0.65; 1.37], p = 0.02) and spinal cord injury (0.50 [0.14; 0.85], p = 0.006), compared with sham. No effect was found for outcomes: mobility and balance., Conclusion: Supplementary repetitive transcranial magnetic stimulation may promote rehabilitation focused on ambulation and muscle strength and overall lower-limb functional recovery in individuals with stroke, Parkinson's disease and spinal cord injury. Further evidence is needed to extrapolate these findings.
- Published
- 2022
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18. Trochanteric stabilizing plate in the treatment of trochanteric fractures: a scoping review.
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Alm CE, Gjertsen JE, Basso T, Matre K, Rörhl S, Madsen JE, and Frihagen F
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- Humans, Bone Plates, Bone Screws, Fracture Fixation, Internal methods, Hip Fractures surgery
- Abstract
Background and purpose - The trochanteric stabilizing plate (TSP) may be used as an adjunct to a sliding hip screw (SHS) in the treatment of trochanteric fractures to increase construct stability. We performed a scoping review of the literature to clarify when and how the TSP may be useful.Methods - A systematic search was performed in 5 databases and followed by a backwards-and-forwards citation search of the identified papers. 24 studies were included.Results - 6 biomechanical studies and 18 clinical studies were included in the review. The studies presented mainly low-level evidence. All studies were on unstable trochanteric fractures or fracture models. Due to the heterogeneity of methods and reporting, we were not able to perform a meta-analysis. In the biomechanical trials, the TSP appeared to increase stability compared with SHS alone, up to a level comparable with intramedullary nails (IMNs). We identified 1,091 clinical cases in the literature where a TSP had been used. There were 82 (8%) reoperations. The rate of complications and reoperations for SHS plus TSP was similar to previous reports on SHS alone and IMN. It was not possible to conclude whether the TSP gave better clinical results, when compared with either SHS alone or with IMN.Interpretation - The heterogeneity of methods and reporting precluded any clear recommendations on when to use the TSP, or if it should be used at all.
- Published
- 2021
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19. The rise of registry-based research: a bibliometric analysis.
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Romanini E, Schettini I, Torre M, Venosa M, Tarantino A, Calvisi V, and Zanoli G
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- Humans, Arthroplasty, Bibliometrics, Biomedical Research trends, Publications trends, Registries
- Abstract
Background and purpose - The main purpose of arthroplasty registries is to collect information on patients, techniques, and devices to monitor and improve the outcome of the specific procedure. This study analyses the role played by registries in the orthopedic research community and describes publication trends, characteristics, and patterns of this field of research.Patients and methods - A descriptive-bibliometric review was conducted. Scopus was the database used for the research. All articles published from 1991 to December 2020 containing keywords related to registries and arthroplasty were considered. In particular, the following dimensions were analyzed in detail: (i) papers/year; (ii) journals; (iii) countries; (iv) research growth rate; (v) collaboration among countries. VOSviewer software was used to perform the bibliometric analysis. Finally, the 50 most cited papers of the last 10 years were briefly analyzed.Results - 3,933 articles were identified. There has been growing interest in the topic since 2010. Acta Orthopaedica ranked first for the number of articles published. The country with the largest number of articles citing registries was the United States, followed by the United Kingdom and Sweden. The relative number of articles per 100,000 inhabitants is 0.60 for Europe and 0.38 for the United States. The literature in this research area has an average yearly growth rate of 28%.Interpretation - The publication rate in the field of arthroplasty registries is constantly growing with a noteworthy impact in the evolution of this research and clinical area. The growth rate is significantly higher than that of arthroplasty literature (28% vs. 10%) and the collaboration among countries is strong and increasing with time.
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- 2021
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20. Management of skin graft donor site in pediatric patients with tumescent technique and AQUACEL ® Ag foam dressing.
- Author
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Shahzad F
- Subjects
- Bandages, Child, Child, Preschool, Humans, Skin Transplantation, Transplant Donor Site surgery, Carboxymethylcellulose Sodium, Occlusive Dressings
- Abstract
Split thickness skin graft donor sites are challenging to manage in children because of patient fear and anxiety. Therefore, strategies that minimize the frequency of dressing change are beneficial. This paper describes a technique to simplify wound care for split thickness skin graft donor sites. A tumescent solution of saline containing 0.25% bupivacaine with epinephrine is infiltrated into the graft donor site. Skin grafts are harvested with an electric dermatome. The donor sites are dressed with AQUACEL
® Ag Foam, which is a sodium carboxymethylcellulose hydrofiber dressing that contains silver ions. A total of 17 split thickness skin grafts were performed with this technique. Patient age ranged from 2.4 year to 16.9 years (average 12 years). The AQUACEL® Ag Foam dressings were removed at an average of 23 days (range 11 to 31 days) at which time complete donor site epithelialization was seen in 13/17 (76.5%) patients. The remaining 4 patients had < 5% of the donor site that had not epithelialized; these went on to heal uneventfully with a brief period of petrolatum gauze dressing changes. Two patients had foul smelling discharge under the dressing that resolved promptly with dressing removal. The above technique allows the primary dressing to stay in place long enough for epithelialization to take place. The obviation of dressing changes in the early post-operative period results in patient comfort and care giver convenience.- Published
- 2021
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21. Towards standardized reporting of service organization in rehabilitation for clinical trials.
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Nugraha B, Andelic N, Søberg HL, Engen G, Kirkevold M, Røe C, and Gutenbrunner C
- Subjects
- Humans, Clinical Trials as Topic standards, Rehabilitation standards, Standard of Care standards
- Abstract
Meta-analysis of clinical trials in rehabilitation is often inconclusive, even when similar interventions are investigated. A possible reason for this is the influence of the settings in which rehabilitation services are delivered. Examples show that factors related to service organization in rehabilitation can influence study outcomes. This, in particular, is relevant, as contextual factors in rehabilitation are known to influence the participation and functioning of persons with disability. The Consolidated Statement of Reporting Trials (CONSORT) group and other initiatives published standards for reporting relevant factors for clinical trials. However, description of the rehabilitation setting of factors related to rehabilitation service provision is under-represented. Systematic reviews show that, on the one hand, these factors are scarcely reported, and only a few studies systematically evaluated the influence of factors related to service organization on rehabilitation outcomes. The International Classification of Service Organization in Rehabilitation (ICSO-R) provides a framework to systematically describe rehabilitation services. It contains 40 categories and sub-categories for the domains "provider" and "service delivery". Therefore, it is important and relevant to develop a minimum reporting set for factors relevant to service organization for rehabilitation trials. This paper sets out a methodological approach for this purpose, including literature reviews, Delphi survey focus group discussion, and consensus conference.
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- 2021
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22. Does pediatric hand transplantation undermine a child's right to an open future?
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MacKenzie J, Selvaggi G, and Sassu P
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- Child, Humans, Hand Transplantation
- Abstract
To date, pediatric hand transplantations have only been performed twice. The ethical issue most often discussed in the literature on this surgery concerns the risks of immunosuppression. While these risks are significant, they can be at least partially mitigated by selecting for patients who are already immunocompromised. Nevertheless, as we will argue, pediatric hand transplantation raises ethical issues that go beyond the risks of immunosuppression. In this paper, we focus on three additional ethical issues: the fact that pediatric hand transplantation aims to improve, rather than save life; the fact that it is an experimental surgery; and the fact that it will be performed on non-autonomous patients whose 'right to an open future' may potentially be undermined by the surgery. Taken together, we think that these considerations suggest that transplantation should be postponed until a child is mature enough to make their own decision about it.
- Published
- 2021
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23. Inception cohort of the Swiss Spinal Cord Injury Cohort Study (SwiSCI): Design, participant characteristics, response rates and non-response.
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Fekete C, Gurtner B, Kunz S, Gemperli A, Gmünder HP, Hund-Georgiadis M, Jordan X, Schubert M, Stoyanov J, and Stucki G
- Subjects
- Cohort Studies, Female, Humans, Male, Middle Aged, Prospective Studies, Switzerland, Spinal Cord Injuries rehabilitation
- Abstract
Objectives: To provide a methodological reference paper for the inception cohort of the Swiss Spinal Cord Injury Cohort Study (SwiSCI), by detailing its methodological features and reporting on participant characteristics, response rates and non-response bias., Design: Prospective cohort study starting in 2013 in all 4 specialized rehabilitation centres in Switzerland., Subjects: Included are 655 newly diagnosed first rehabilitation patients aged ≥16 years with traumatic or non-traumatic spinal cord injury (TSCI, NTSCI)., Methods: Descriptive statistics were used to depict participant characteristics and to compare characteristics of responders and non-responders. Logistic regressions were conducted to estimate non-response bias., Results: The sample consisted of 69% males, with mean age 53.5 years, 57.9% TSCI, 60.7% paraplegia and 78.8% incomplete SCI. Males and younger persons more often sustained TSCI and more severe SCI, resulting in longer duration of rehabilitation. Complete lesions were more prevalent in TSCI compared to NTSCI. The response rate was 47.5% and study participation was less likely in females, older persons, persons with lower functional independence and those with NTSCI., Conclusion: SwiSCI inception cohort data enable the estimation of epidemiological figures of SCI in Switzerland, and prognostic and trajectory modelling of outcomes after SCI to guide policy, service provision and clinical practice.
- Published
- 2021
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24. Teaching functioning, disability and rehabilitation to first year medical students.
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Gutenbrunner C, Kubat B, Kröhn S, Haller H, Schiller J, Korallus C, and Sturm C
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- Curriculum, Humans, Students, Medical, Disabled Persons education
- Abstract
Background: Many patients have disabilities; it is therefore essential that medical education includes comprehensive teaching on disability and rehabilitation. In 2006 Hannover Medical School implemented an introductory course in the curriculum for medical students, on how to communicate with persons with disability and the need for rehabilitation. The course, entitled "Introduction to medicine", has the main goals of teaching the strategy and systematic approach of medicine to solving patients' problems., Methods: This paper describes the content, methods and outcomes of 1 of the 4 main themes of the "Introduction to medicine" course; the theme "Pain and disability", which is covered in the second week of the course., Results: Evaluation of the "Pain and disability" module found that students' ratings for the category "patient involvement" were very high (93%), whereas their ratings for the category "examination of student knowledge" were low. The overall rating of the module was "good" (10.8 out of 15 points), but not "very good"., Conclusion: The concept of the "Pain and disability" module is feasible and successful, even though it is scheduled early in the first year of the curriculum and approximately 350 students participate. Factors related to this success are: a mixture of teaching knowledge, supporting students' understanding, and applying communication and physical examination skills.
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- 2021
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25. A practical guide to optimizing the benefits of post-stroke spasticity interventions with botulinum toxin A: An international group consensus.
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Francisco GE, Balbert A, Bavikatte G, Bensmail D, Carda S, Deltombe T, Draulans N, Escaldi S, Gross R, Jacinto J, Ketchum N, Molteni F, Moraleda S, ODell MW, Reebye R, Säterö P, Verduzco-Gutierrez M, Walker H, and Wissel J
- Subjects
- Consensus, Humans, Neuromuscular Agents therapeutic use, Botulinum Toxins, Type A therapeutic use, Muscle Spasticity drug therapy, Stroke complications
- Abstract
This consensus paper is derived from a meeting of an international group of 19 neurological rehabilitation specialists with a combined experience of more than 250 years (range 4-25 years; mean 14.1 years) in treating post-stroke spasticity with botulinum toxin A. The group undertook critical assessments of some recurring practical challenges, not yet addressed in guidelines, through an exten-sive literature search. They then discussed the results in the light of their individual clinical experience and developed consensus statements to present to the wider community who treat such patients. The analysis provides a comprehensive overview of treatment with botulinum toxin A, including the use of adjunctive therapies, within a multidisciplinary context, and is aimed at practicing clinicians who treat patients with post-stroke spasticity and require further practical guidance on the use of botulinum toxin A. This paper does not replicate information published elsewhere, but instead aims to provide practical advice to help optimize the use of botulinum toxin A and maximize clinical outcomes. The recommendations for each topic are summarized in a series of statements. Where published high-quality evidence exists, the recommendations reflect this. However, where evidence is not yet conclusive, the group members issued statements and, in some cas-es, made recommendations based on their clinical experience.
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- 2021
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26. Redeployment of the trainee orthopaedic surgeon during COVID-19: a fish out of water?
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Faria G, Tadros BJ, Holmes N, Virani S, Reddy GK, Dhinsa BS, and Relwani J
- Subjects
- Clinical Competence, Employment, Humans, Organizational Innovation, SARS-CoV-2, United Kingdom, Workplace, Attitude of Health Personnel, COVID-19 epidemiology, COVID-19 prevention & control, Infection Control methods, Infection Control organization & administration, Orthopedic Surgeons organization & administration, Orthopedic Surgeons psychology, Orthopedics organization & administration, Orthopedics trends, Return to Work statistics & numerical data
- Abstract
Background and purpose - COVID-19 has had a significant impact on health services and the entire healthcare sector, including trauma and orthopaedics, has been compelled to adapt. At the heart of this was the redeployment of the orthopaedic trainees to support "frontline specialties". This paper sheds light on the experience of orthopaedic trainees in redeployment. Methods - In this retrospective study, we asked orthopaedic trainees in the KSS (Kent, Surrey, Sussex) and London Deaneries to complete a survey regarding their experience in redeployment during the COVID-19 outbreak. The study took place in the Kent, Surrey, Sussex, and London regions of the United Kingdom over a period of 8 weeks from 15th of March 2020 until 15th of May 2020. The study was based at East Kent Hospitals University NHS Foundation Trust and participants were recruited from a number of secondary and tertiary care centres across the region. 120 orthopaedic trainees were contacted, working in 21 teaching hospitals. Of these, 40 trainees (30%) from 13 hospitals responded and completed the survey. Results - 50% of the surveyed trainees were redeployed to other specialties. Trainees spent varying amounts of time in the redeployed speciality and gave differing views on how comfortable they felt and how useful they felt the experience was. One-third of trainees experienced symptoms and/or tested positive for COVID-19 and the majority of these were redeployed to other specialties. Interpretation - Orthopaedic training appears to have taken a temporary back seat at this time but trainees have made a significant contribution to reinforcing key front-line specialties in the fight against COVID-19.
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- 2020
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27. Cognitive training for the prevention of skill decay in temporarily non-performing orthopedic surgeons.
- Author
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Kelc R, Vogrin M, and Kelc J
- Subjects
- Guidelines as Topic, Clinical Competence standards, Cognition, Education, Medical, Continuing methods, Orthopedics education, Orthopedics standards
- Abstract
Surgical tasks are prone to skill decay. During unprecedented circumstances, such as an epidemic, personal illness, or injury, orthopedic surgeons may not be performing surgical procedures for an uncertain period of time. While not being able to execute regular surgical tasks or use surgical simulators, skill decay can be prevented with regular mental practice, using a scientifically proven skill acquisition and retaining tool. This paper describes different theories on cognitive training answering the question on how it works and offers a brief review of its application in surgery. Additionally, practical recommendations are proposed for performing mental training while not performing surgical procedures.
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- 2020
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28. Physical child abuse demands increased awareness during health and socioeconomic crises like COVID-19.
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Martinkevich P, Larsen LL, Græsholt-Knudsen T, Hesthaven G, Hellfritzsch MB, Petersen KK, Møller-Madsen B, and Rölfing JD
- Subjects
- Child, Child Abuse diagnosis, Economic Recession, Humans, Socioeconomic Factors, Awareness, COVID-19, Child Abuse prevention & control, Child Abuse statistics & numerical data
- Abstract
Background and purpose - Physical abuse of children, i.e., nonaccidental injury (NAI) including abusive head trauma (AHT) is experienced by up to 20% of children; however, only 0.1% are diagnosed. Healthcare professionals issue less than 20% of all reports suspecting NAI to the responsible authorities. Insufficient knowledge concerning NAI may partly explain this low percentage. The risk of NAI is heightened during health and socioeconomic crises such as COVID-19 and thus demands increased awareness. This review provides an overview and educational material on NAI and its clinical presentation.Methods - We combined a literature review with expert opinions of the senior authors into an educational paper aiming to help clinicians to recognize NAI and act appropriately by referral to multidisciplinary child protection teams and local authorities.Results - Despite the increased risk of NAI during the current COVID-19 crisis, the number of reports suspecting NAI decreased by 42% during the lockdown of the Danish society. Healthcare professionals filed only 17% of all reports of suspected child abuse in 2016.Interpretation - The key to recognizing and suspecting NAI upon clinical presentation is to be aware of inconsistencies in the medical history and suspicious findings on physical and paraclinical examination. During health and socioeconomic crises the incidence of NAI is likely to peak. Recognition of NAI, adequate handling by referral to child protection teams, and reporting to local authorities are of paramount importance to prevent mortality and physical and mental morbidity.
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- 2020
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29. Strategies for learning glossopharyngeal breathing in boys with Duchenne muscular dystrophy: A feasibility case series.
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Haruyama K, Yamaha Y, Ito M, Otsuka T, and Kawakami M
- Subjects
- Adult, Feasibility Studies, Humans, Male, Young Adult, Muscular Dystrophy, Duchenne complications, Respiration genetics
- Abstract
Objective: To propose alternative learning strategies for glossopharyngeal breathing in patients with Duchenne muscular dystrophy (DMD) and healthy men., Design: A feasibility study with small case series., Subjects: Five boys with DMD and 7 male physical therapists as healthy controls who had not learned glossopharyngeal breathing., Methods: Participants were instructed in a glossopharyngeal breathing protocol, including induction methods comprising sucking motions and phonation with inhalation. The protocol consisted of 1-6 sessions (10-15 min each; total 60 min). Criteria for glossopharyngeal breathing mastery were vital capacity with glossopharyngeal insufflation (VCGI)/VC ratio > 1.10 for the DMD group and > 1.05 for the Healthy group. Feasibility outcomes were time required for mastering glossopharyngeal breathing, self-reported outcomes, adverse events and drop-outs., Results: All participants learned glossopharyngeal breathing within the allocated 60 min. Mean VCGI/VC ratio was 1.31 for the DMD group and 1.09 for the Healthy group. No adverse events or drop-outs were encountered during the protocol. In most cases, self-reported outcomes showed that motivation increased and difficulty decreased., Conclusion: Induction methods for sucking motions and phonation with inhalation for glossopharyngeal breathing learning are feasible. This paper proposes alternative strategies for glossopharyngeal breathing learning in boys with DMD and their instructors.
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- 2020
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30. Perceived environmental barriers for people with spinal cord injury in Germany and their influence on quality of life.
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Bökel A, Dierks ML, Gutenbrunner C, Weidner N, Geng V, Kalke YB, Liebscher T, Abel FR, and Sturm C
- Subjects
- Adult, Aged, Aged, 80 and over, Cross-Sectional Studies, Female, Germany, Humans, Male, Middle Aged, Surveys and Questionnaires, Young Adult, Environment, Quality of Life psychology, Spinal Cord Injuries epidemiology
- Abstract
Objective: The German Spinal Cord Injury Survey is part of the International Spinal Cord Injury Survey, which aims to collect data about the life experience of persons with spinal cord injury worldwide. This paper reports on the perceived environmental barriers of the German study population and their associations with quality of life., Design: Cross-sectional explorative observational study using survey data., Participants: A total of 1,479 persons with spinal cord injury aged 18 years and older., Methods: After descriptive analyses, exploratory factor analysis was used to build groups of environmental barriers. Logistic regressions were performed to assess correlates of perceived environmental barriers. Spearman's correlations were used to analyse the association between perceived barriers and quality of life., Results: Barriers regarding infrastructure had a relatively large impact. Barriers in relation to people's attitudes towards spinal cord injury and the equipment of people with spinal cord injury had a relatively small impact on the lives of people with spinal cord injury. Several subpopulations showed a higher risk in experiencing barriers. Quality of life decreased with increasing experience of barriers., Conclusion: The most life-hardening barriers were identified related to infrastructure, a category in which most barriers are modifiable, for example, buildings or transportation.
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- 2020
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31. Can MRI differentiate between atypical cartilaginous tumors and high-grade chondrosarcoma? A systematic review.
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Deckers C, Steyvers MJ, Hannink G, Schreuder HWB, de Rooy JWJ, and Van Der Geest ICM
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- Bone Neoplasms diagnosis, Chondroma diagnosis, Chondrosarcoma diagnosis, Diagnosis, Differential, Humans, Magnetic Resonance Imaging, Bone Neoplasms diagnostic imaging, Chondroma diagnostic imaging, Chondrosarcoma diagnostic imaging
- Abstract
Background and purpose - Adequate staging of chondroid tumors at diagnosis is important as it determines both treatment and outcome. This systematic review provides an overview of MRI criteria used to differentiate between atypical cartilaginous tumors (ACT) and high-grade chondrosarcoma (HGCS).Patients and methods - For this systematic review PubMed and Embase were searched, from inception of the databases to July 12, 2018. All original articles describing MRI characteristics of pathologically proven primary central chondrosarcoma and ACT were included. A quality appraisal of the included papers was performed. Data on MRI characteristics and histological grade were extracted by 2 reviewers. Meta-analysis was performed if possible. The study is registered with PROSPERO, CRD42018067959.Results - Our search identified 2,132 unique records, of which 14 studies were included. 239 ACT and 140 HGCS were identified. The quality assessment showed great variability in consensus criteria used for both pathologic and radiologic diagnosis. Due to substantial heterogeneity we refrained from pooling the results in a meta-analysis and reported non-statistical syntheses. Loss of entrapped fatty marrow, cortical breakthrough, and extraosseous soft tissue expansion appeared to be present more often in HGCS compared with ACT.Interpretation - This systematic review provides an overview of MRI characteristics used to differentiate between ACT and HGCS. Future studies are needed to develop and assess more reliable imaging methods and/or features to differentiate ACT from HGCS.
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- 2020
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32. Need for comprehensive management of frailty at an individual level: European perspective from the advantage joint action on frailty.
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Gabrovec B, Antoniadou E, Soleymani D, Kadalska E, Carriazo AM, Samaniego LL, Csizmadia P, Hendry A, Bacaicoa OA, Jelenc M, Selak Š, Patsios D, Stolakis K, Mentis M, Papathanasopoulos F, Panagiotopoulos E, and Mañas LR
- Subjects
- Aged, Aged, 80 and over, Europe, Female, Frailty, Humans, Male, Geriatric Assessment methods
- Abstract
Objectives: ADVANTAGE Joint Action is a large collaborative project co-founded by the European Commission and its Member States to build a common understanding of frailty for Member States on which to base a common management approach for older people who are frail or at risk of developing frailty. One of the key objectives of the project is presented in this paper; how to manage frailty at the individual level., Methods: A systematic review of the literature was conducted, including grey literature and good practices when possible., Results: The management of frailty should be directed towards comprehensive and holistic treatment in multiple and related fields. Prevention requires a multifaceted approach addressing factors that have resonance across the individual's life course. Comprehensive geriatric assessment to diagnose the condition and plan a personalized multidomain treatment increases better outcomes. Multicomponent exercise programmes, adequate protein and vitamin D intake, when insufficient, and reduction in polypharmacy and inadequate prescription, are the most effective strategies found in the literature to manage frailty effectively., Conclusion: Frailty can be effectively prevented and managed with a multidomain intervention strategy based on comprehensive geriatric assessment.
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- 2020
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33. Abobotulinumtoxina injections in shoulder muscles to improve adult upper limb spasticity: Results from a phase 4 real-world study and a phase 3 open-label trial.
- Author
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Lejeune T, Khatkova S, Turner-Stokes L, Picaut P, Maisonobe P, Balcaitiene J, and Boyer FC
- Subjects
- Acetylcholine Release Inhibitors pharmacology, Adult, Botulinum Toxins, Type A pharmacology, Female, Humans, Injections, Male, Middle Aged, Neuromuscular Agents pharmacology, Treatment Outcome, Acetylcholine Release Inhibitors therapeutic use, Botulinum Toxins, Type A therapeutic use, Muscle Spasticity drug therapy, Neuromuscular Agents therapeutic use, Shoulder abnormalities
- Abstract
Botulinum toxins, such as abobotulinumtoxinA, are used to treat spasticity (muscle overactivity) in arm muscles. Spasticity in shoulder muscles occurs in many patients following a stroke. Shoulder spasticity can be painful and limit limb movement. This paper compares the results from patients who did and those who did not receive abobotulinumtoxinA injections in shoulder muscles (among other arm muscles) in 2 studies. In both studies, the results showed that more patients receiving treatment in shoulder muscles chose pain as a key goal for treatment and had reduced pain following treatment compared with patients not treated in the shoulder. In addition, patients receiving shoulder injections showed further improvement in arm movement compared with those not receiving shoulder injections. Overall, these results suggest that abobotulinumtoxinA treatment in shoulder muscles may improve outcomes for patients with arm spasticity involving the shoulder.
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- 2020
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34. Post-obstructive diuresis; underlying causes and hospitalization.
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Leinum LR, Berthelsen C, and Azawi N
- Subjects
- Aged, Hospitalization, Humans, Male, Retrospective Studies, Diuresis, Urinary Catheterization, Urinary Retention physiopathology, Urinary Retention therapy
- Abstract
Objective: This paper aims to estimate the incidence of post-obstructive diuresis (POD) among patients with urinary retention, explore possible underlying causes and identify patients who need hospitalization. Material and methods: This retrospective study includes patients admitted for urinary retention in Zealand University Hospital, Denmark. We collected demographic characteristics, health information and laboratory results from patients' charts and analyzed data statistically. Results: We assessed 64 patients, and POD occurred in 29.7%. A significant correlation was observed between POD and residual urine, serum creatinine, serum urea and systolic and diastolic blood pressure. We identified increased residual urine volume as an independent predictor of POD by OR 1.21 (95% CI: 1.06-1.40), p = 0.006 per 100 mL and creatinine of >120 umol/L is an independent predictor of POD by OR 7.17 (95% CI; 1.63-31.37), p = 0.009. Patients with residual urine at the time of diagnosis of more than 1150 ml will suffer POD with a probability of area under curve (AUC) 0.874 ( p < 0.001) with 84% sensitivity and 78% specificity. Patients with creatinine >120 umol/L will suffer POD with a probability of AUC 0.774 ( p < 0.001) with 68% sensitivity and 82% specificity. Conclusion: In this small retrospective study residual urine of more than 1150 mL and elevated creatinine are independent predictors of POD in patients with urinary retention. However, larger prospective studies are needed to confirm these findings.
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- 2020
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35. Vision and strategy for healthcare: Competence is a necessity.
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Malmivaara A
- Subjects
- Humans, Delivery of Health Care standards, Health Policy trends
- Abstract
Well-designed, evidence-based vision and strategy are fundamental requirements for successful healthcare. This paper reviews previous comprehensive healthcare strategies (Institute of Medicine statement, Value-based healthcare, and Triple aim strategy) published in peer-reviewed scientific journals, and presents an alternative proposal for healthcare vision and strategy. The proposed strategy includes, as prerequisites, competence of staff, healthcare leaders and leaders of health policy, and a well-functioning healthcare system. It is necessary to optimize the financing, reimbursement and incentives, organization, and regulation of the healthcare system. Strategic means to successful healthcare are to improve staff competence, implement current scientific evidence, document clinical and system-related issues, improve quality, and carry out benchmarking with peers. The vision for healthcare is to provide continuous improvement in services, in terms of accessibility, quality, fairness, effectiveness, safety and efficiency, to the patients (customers) and to the population. The new proposal shares many issues with strategies published previously. This paper sets out the prerequisites for the proposed strategy. A common vision, high levels of integrity, and a commitment to providing the best for patients and the population, are of fundamental importance. Competence at all levels of healthcare is a necessity.
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- 2020
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36. The role of botulinum toxin in multimodal treatment of spasticity in ambulatory children with spastic Cerebral Palsy: extensive evaluation of a cost-effectiveness trial.
- Author
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Bussmann JBJ, Pangalila RF, Stam HJ, and Schasfoort F
- Subjects
- Botulinum Toxins, Type A pharmacology, Child, Child, Preschool, Female, Humans, Male, Neuromuscular Agents pharmacology, Treatment Outcome, Botulinum Toxins, Type A therapeutic use, Cerebral Palsy drug therapy, Combined Modality Therapy methods, Cost-Benefit Analysis methods, Neuromuscular Agents therapeutic use
- Abstract
Background: A cost-effectiveness trial (the Space Bop study) on the added value of botulinum toxin injections (BoNT-A) in the leg muscles, as part of a multimodal intervention for ambulatory children with spastic cerebral palsy in the context of a single distinct cycle of care was performed recently by our group. For a broad set of effect outcomes, we found that BoNT-A had no added value if children received comprehensive rehabilitation. However, this counterintuitive finding was met with scepticism., Objective: Since several noteworthy facts and experiences were recorded during the course of the trial and the dissemination phase, the aim of this paper was to describe and discuss some crucial aspects of, and barriers to, the Space Bop study, related to context and perspective, design and results, as well as publication and implementation., Methods: This paper discusses 5 issues: (i) the design, interpretation and presentation of previous research; (ii) the role of one's own clinical experience and interpretation; (iii) the aims of (BoNT-A) treatment; (iv) conflict of interest, role of industry, and the role of history; (v) optimal treatment modalities and dose-response relationships., Conclusion: Despite the unambiguous findings from the Space Bop study, several factors hindered acceptance of the results. Awareness of these factors is important when performing rehabilitation research and disseminating and implementing research findings.
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- 2020
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37. Olle Höök Lectureship 2019: The changing world of stroke rehabilitation.
- Author
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Sunnerhagen KS
- Subjects
- Humans, Sweden, Robotics trends, Stroke, Stroke Rehabilitation trends
- Abstract
The paper presents a summary of the Olle Höök lecture, which was presented at the Baltic North-Sea Forum in Oslo, Sweden, in October 2019. The paper aims to provide a worldwide picture of stroke, developments in this field, and the evolution of stroke rehabilitation. It sets out the background to, evidence for, and content of the comprehensive stroke unit. The paper also describes some rehabilitation techniques based on neurophysiology, the use of robotics, and the evidence level for interventions. Organization of the stroke care chain and different aspects of rehabilitation during its trajectory are described. However, the need for rehabilitation is often not met, due to restricted and unevenly distributed resources. With increasing knowledge of neurophysiology and evidence from meta-analyses, the content of stroke rehabilitation will continue to evolve.
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- 2020
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38. One-year follow-up after urethroplasty, with the focus on both lower urinary tract and erectile function.
- Author
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Míka D, Krhut J, Ryšánková K, Sýkora R, Luňáček L, and Zvara P
- Subjects
- Adult, Aged, Follow-Up Studies, Humans, Male, Middle Aged, Penile Erection, Prospective Studies, Time Factors, Urethra physiology, Urinary Bladder physiology, Urologic Surgical Procedures, Male methods, Urethra surgery, Urethral Stricture surgery
- Abstract
Background: Urethral stricture disease (USD) represents a complex urological problem. Urethroplasty is considered the gold standard for the treatment of USD. Most available studies report outcome data obtained from retrograde urethrography and uroflowmetry. Only a limited number of papers describe the effect of urethroplasty on erectile function and their results are inconsistent. The goal of this prospective study was to evaluate the effect of urethroplasty on both lower urinary tract and erectile function using objective parameters and standardized patient-reported outcome measurement tools. Materials and Methods: A total of 55 consecutive patients with USD were enrolled into the study. Patients underwent ventral onlay urethroplasty, urethroplasty according to the Asopa technique, dorsal onlay urethroplasty, cutaneous flap urethroplasty using the Orandi technique or anastomotic repair. All patients were evaluated using uroflowmetry, urethrography, the PROM-USS questionnaire and the International Index of Erectile Function-5 questionnaire (IIEF-5) pre-operatively and consequently post-op, in 3-month intervals. This study presents the comparison of baseline pre-op parameters and parameters 12 months after the surgery using the Wilcoxon signed rank test, Wilcoxon rank sum test and the Kruskal-Wallis one-way analysis of variance. Results: A significant improvement in uroflowmetry parameters, all domains of the PROM-USS questionnaire, as well as the overall score of the IIEF-5 was observed. No statistically significant differences between sub-groups were found when comparing treatment results in patients with short versus long strictures and patients with penile urethra stricture versus bulbar or membranous urethra stricture. Conclusions: Urethroplasty yielded very good functional results with respect to both lower urinary tract and erectile functions.
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- 2020
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39. Fostering the highest educational standards in Physical and Rehabilitation Medicine: The European PRM board strategy for ensuring overall quality of rehabilitation education and care.
- Author
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Barotsis N, Franchignoni F, Frischknecht R, Juocevicius A, McNamara A, Michail X, Vanderstraeten G, Viton JM, and Ceravolo MG
- Subjects
- European Union, Humans, Clinical Competence standards, Disabled Persons rehabilitation, Physical and Rehabilitation Medicine education, Physical and Rehabilitation Medicine standards
- Abstract
The harmonization of staff education is a key element for ensuring the highest standard of rehabilitation care across Europe. With this aim, the European Union of Medical Specialists (UEMS) has created a Common Training Framework, which consists of a common set of knowledge, skills and competencies for postgraduate medical training. As a body linked to the Physical and Rehabilitation (PRM) Section of the UEMS, the European PRM Board is committed to promoting the harmonization of PRM physicians qualifications. The European PRM Board accomplishes this mission, not only by determining the theoretical knowledge necessary for the practice of the PRM specialty, and the core competencies (training outcomes) to be achieved at the end of training, but also by ascertaining that a standard level of education is achieved and maintained by PRM physicians, through a medically driven system of certification. This paper provides an overview of the methodology and outcomes of the European PRM Board examination, while showing how the approach to PRM education should be considered as a reference point by scientific societies, higher education institutions, health policymakers, patients associations, and all the other bodies caring for high-quality rehabilitation provision to disabled people, at the national and European level.
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- 2019
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- View/download PDF
40. Evaluating a global health partnership rehabilitation training programme in Madagascar.
- Author
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Locke HN, Doctors S, Randriamampianina I, Chamberlain MA, and O Connor RJ
- Subjects
- Humans, Madagascar, Disabled Persons education, Disabled Persons rehabilitation, Global Health standards, Rehabilitation methods
- Abstract
Objective: Rehabilitation services play an important role in optimizing functional ability and societal integration for people with disabilities. The Madagascar Rehabilitation Programme (2011-2013) resulted from a global training partnership and led to 8 doctors achieving a university diploma in rehabilitation medicine. This paper describes a 2014 evaluation of the programme methods, results and learning points., Methods: A combination of qualitative methods was used for the evaluation, based on a Theory of Change model, with informants from Madagascar and the UK., Results: Malagasy trainees and UK volunteers gained new theoretical knowledge and practical skills. For Madagascar, it led to changes in working practice and the formation of a national rehabilitation association. Key to its success was the strong collaboration between Malagasy and UK professionals, with support from the University and Ministry of Health in Madagascar, and the UK partners. Having a clear common vision ensured the programme met the needs of the Malagasy clinicians., Conclusion: Rehabilitation is increasingly recognized as an important focus for international development. Successful rehabilitation training programmes can be achieved at modest costs with global health partnerships. The combination of factors that enabled this programme to be a success is reproducible in other contexts.
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- 2019
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41. Evidence-based rehabilitation therapy following surgery for (peri-)articular fractures: A systematic review.
- Author
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Schnackers MLAP, van Horn YY, Meys GHH, Brink PRG, Smeets RJEM, and Seelen HAM
- Subjects
- Humans, Fractures, Bone rehabilitation, Fractures, Bone surgery, Treatment Outcome
- Abstract
Objective: To assess the availability of explicitly reported protocols describing post-surgery rehabilitation of (peri-)articular fractures of the proximal humerus, acetabulum and/or tibial plateau, and to critically review any scientific evidence on the effectiveness of these protocols., Data Sources: MEDLINE (PubMed), Cochrane databases, CINAHL, PEDro and Embase (Ovid) were searched to November 2018. Furthermore, stakeholder internet sites, clinical guidelines and standard textbooks were searched., Study Selection: Screening was performed independently by 2 researchers based on a priori defined eligibility criteria., Data Synthesis: Five papers addressed post-surgical rehabilitation of proximal humerus fractures, 1 paper that of acetabulum fractures. No eligible information was found on stakeholder sites or in standard textbooks. Overall, the main focus of the protocols identified was on the International Classification of Functioning, Disability and Health (ICF) Body Functions and Structures level. In general, little information about therapy dosage was reported. None of the protocols provided scientific evidence on which the content of described rehabilitation programmes was based., Conclusion: This review reveals a paucity of explicitly formulated protocols focussing on post-surgical rehabilitation of common (peri-)articular fractures targeting patient-centred care at all ICF levels. There is a need for more scientific evidence on which to base protocols regarding common (peri-)articular fracture rehabilitation.
- Published
- 2019
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42. Comparison of aesthetic outcome with round and three-armed star flap umbilicoplasty.
- Author
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Kurt Yazar S, Serin M, Diyarbakırlıoğlu M, Şirvan SS, Irmak F, and Yazar M
- Subjects
- Abdominoplasty, Adult, Cicatrix, Hypertrophic etiology, Epigastric Arteries, Female, Follow-Up Studies, Humans, Middle Aged, Patient Satisfaction, Perforator Flap, Plastic Surgery Procedures adverse effects, Esthetics, Plastic Surgery Procedures methods, Umbilicus surgery
- Abstract
Background: The umbilicus is an indicative aesthetic component of the abdomen. Many umbilicoplasty techniques have been defined and the most commonly used method is the round incision technique. In this paper, we present a new umbilicoplasty technique involving the use of a three-armed star flap and compare it with the round technique. Methods: Forty-eight female patients who underwent umbilicoplasty during abdominoplasty and free deep inferior epigastric perforator flap (DIEP) procedures between February 2011 and December 2016 were included in the study. Twenty patients had round umbilicoplasty, whereas in the remaining 28 patients the three armed star flap technique was used. Aesthetic outcomes of both techniques were evaluated by a questionnaire which was completed by the patients and two independent surgeons. Results: The mean follow-up period was 22 months. Hypertrophic scarring was seen in one patient with the three armed star flap technique and in two patients with the round technique and a cicatricial ring formation occurred in one patient with the round technique. The patient and surgeon questionnaire scores were significantly higher in the 3-armed star flap group. ( p < .05) Conclusion: In this study, round umbilicoplasty technique has been compared with the three armed star flap technique. Patient satisfaction surveys and evaluation by two independent surgeons revealed better cosmetic results with the new technique. We believe that this new technique could be preferred over the round technique since it prevents stenosis, circular scar contraction and provides a natural contour between the umbilicus and abdomen.
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- 2019
- Full Text
- View/download PDF
43. Assessment for incipient hospital-acquired deconditioning in acute hospital settings: A systematic literature review.
- Author
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Gordon S, Grimmer KA, and Barras S
- Subjects
- Activities of Daily Living, Hospitalization, Humans, Inpatients psychology, Patient Care methods, Patient Care psychology, Psychometrics, Recovery of Function, Rehabilitation Research, Reproducibility of Results, Disability Evaluation, Hospitals statistics & numerical data, Inpatients statistics & numerical data, Outcome Assessment, Health Care methods, Patient Care statistics & numerical data
- Abstract
Objectives: To systematically identify literature reporting on assessment instruments relevant for incipient hospital-acquired deconditioning during acute hospital admissions; evaluate their psychometric properties; and identify individual assessment items to form the basis of a comprehensive acute hospital test battery for hospital-acquired deconditioning., Design and Data Sources: Systematic evidence scan of MEDLINE, CINAHL, PubMed and Google Scholar from database inception to January 2018., Study Selection: Papers reporting psychometric properties of assessment instruments to detect change in body function and structure, relevant to hospital-acquired deconditioning were selected. Included instruments should assess one or more elements of hospital-acquired deconditioning, reflect the short time-frame constraints of acute hospital admissions, and be able to be applied by any healthcare provider. Quality evaluation: Evidence of psychometric properties and utility were assessed using a validated instrument., Data Extraction: Hospital-acquired deconditioning assessment items., Results: Eight potentially-relevant instruments were identified, with moderate-to-good validity and utility, but limited evidence of reliability. These instruments reported a total of 53 hospital-acquired deconditioning assessment items. Seventeen items with measurement periods greater than 3 days were excluded. The remaining items measured anthropometrics, gait, balance, mobility, activities of daily living, and skin integrity., Conclusion: These assessment items provide the basis of a multifaceted evidence-based test battery to comprehensively and repeatedly assess acute hospital inpatient function for incipient hospital-acquired deconditioning.
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- 2019
- Full Text
- View/download PDF
44. Comparison of contraction rates of epigastric and extended dorsal island skin flaps in rats.
- Author
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Certel F, Bayramicli M, and Serin M
- Subjects
- Animals, Necrosis, Rats, Sprague-Dawley, Abdomen surgery, Muscle Contraction, Surgical Flaps pathology
- Abstract
Flap surgery is a wide field in plastic and reconstructive surgery practice and experimental research is needed to improve surgical success. These research is often performed on rats. Rat is a loose-skinned animal and contraction of skin flaps on rats is an underestimated condition. Besides this variable contraction of survived and necrotic tissues may mislead calculations and results. In this study, contraction patterns of epigastric and dorsal island skin flaps were investigated to identify this phenomenon. Forty-two male Sprague-Dawley rats were divided into four groups. Eleven epigastric flaps with unilateral pedicles, 11 epigastric flaps with bilateral pedicles, 10 extended dorsal island skin flaps with unilateral pedicles, and 10 extended dorsal island skin flaps with bilateral pedicles were prepared. Total, necrotic and viable flap areas were calculated from standardized photographs which were taken daily. The animals were placed on marked papers and image processing software was used the calculate flap areas from the photographs. Respect to these daily flap areas, the contraction rates in epigastric flaps were highly significant. The area loss in necrotic tissues were faster than the viable areas. Compared to the epigastric flaps, the contraction was not significant in extended dorsal island skin flaps flap groups. In conclusion, the rat extended dorsal island skin flap is a more reliable model for experimental flap research, which is resistant to contraction, when compared to the epigastric skin flap model.
- Published
- 2019
- Full Text
- View/download PDF
45. A protocol for permissive weight-bearing during allied health therapy in surgically treated fractures of the pelvis and lower extremities.
- Author
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Meys G, Kalmet PHS, Sanduleanu S, van Horn YY, Maas GJ, Poeze M, Brink PRG, and Seelen HAM
- Subjects
- Adult, Clinical Protocols, Female, Fractures, Bone surgery, Humans, Lower Extremity surgery, Male, Middle Aged, Pelvis surgery, Postoperative Period, Recovery of Function, Time Factors, Treatment Outcome, Early Ambulation methods, Fractures, Bone rehabilitation, Lower Extremity injuries, Pelvis injuries, Physical Therapy Modalities, Weight-Bearing
- Abstract
Objective: To optimize rapid clinical recovery and restoration of function and functionality, permissive weight-bearing has been designed as a new aftercare mobilization regimen, within the upper boundary of the therapeutic bandwidth, yet safe enough to avoid overloading. The aim of the present paper is to describe a comprehensive protocol for permissive weight-bearing during allied health therapy and to report on the time to full weight-bearing, as well as the number of complications, in patients with surgically treated fractures of the pelvis and lower extremities undergoing permissive weight-bearing., Patients and Methods: This study included surgically treated trauma patients with (peri)- or intra-articular fractures of the pelvis and lower extremities. A standardized permissive weight-bearing protocol was used for all patients. Time to full weight-bearing and number of complications were recorded., Results: This study included 150 patients, 69% male, with a median age of 48 years (interquartile range (IQR) 33.0, 57.0). The median time to full weight bearing was 12.0 weeks (IQR 6.8, 19.2). The complication rate during rehabilitation was 10%., Conclusion: The permissive weight-bearing protocol, as described, might be beneficial and has potential to be implemented in trauma patients with surgically treated (peri)- or intra-articular fractures of the pelvis and lower extremities.
- Published
- 2019
- Full Text
- View/download PDF
46. A comparison of the academic impact of plastic surgery units in the United Kingdom and Ireland using bibliometric analysis.
- Author
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Trevatt AEJ, Thomson DR, Miller R, Colquhoun M, Idowu AI, and Rahman S
- Subjects
- Bibliometrics, Humans, Ireland, United Kingdom, Hospital Units statistics & numerical data, Publishing statistics & numerical data, Surgery, Plastic
- Abstract
Academic output is just one aspect of a successful career as a plastic surgeon. However, for those with a strong interest in academia, the academic output of a department will likely be a key factor when deciding how to rank jobs. The aim of this study was to quantify and rank the academic output of plastic surgery units across the UK and Ireland. The Institute for Scientific Information (ISI) Web of Science Bibliometric analysis tool was used to collate cumulative (1950-2016), 10 year (2006-2016) and 3 years (2013-2015) research output data for plastic surgery units in the UK and Ireland. Sixty-six plastic surgery units were identified. Departments were ranked for each time period according to the number of papers produced, number of citations (Nc) and h-index (a measure of the impact of scientific output). The top 3 departments for number of papers in the last 10 years were The Royal Free Hospital, London (226) Broomfield Hospital, Chelmsford (218), and Morriston Hospital and Swansea (188). The top 3 for h-number were The Royal Free Hospital (21) Wythenshawe Hospital, Manchester (18) and Morriston Hospital (17). Academic output varies across plastic surgery units in the UK and Ireland. A number of departments have consistently maintained high academic outputs across the years and will be of interest to surgeons hoping to pursue a career in academia.
- Published
- 2019
- Full Text
- View/download PDF
47. 'J' brachioplasty technique in massive weight loss patients.
- Author
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Bocchiotti MA, Ruka E, Spaziante L, Morozzo U, Baglioni EA, and Bruschi S
- Subjects
- Adult, Bariatric Surgery, Female, Humans, Lipectomy, Male, Middle Aged, Operative Time, Postoperative Complications, Retrospective Studies, Arm surgery, Body Contouring methods, Weight Loss
- Abstract
Upper extremity body reshaping is a very frequent surgical procedure in massive weight loss patients. Many surgeons have presented different patterns of brachioplasty skin excision and a variety of adjunctive techniques, each of them claiming improvements in scar aesthetic, arm shape or overall safety of the procedure. In this pape,r we want to illustrate our personal brachioplasty technique for massive weight loss patients. Our incision design named 'J' Brachioplasty is described. Between March 2013 and March 2016, a retrospective study of patients with massive weight loss and clinical diagnosis of brachial ptosis undergoing surgical reconstruction with 'J' brachioplasty was performed. All patients were treated according to a standard surgical procedure described in detail in the paper. The presence of axillary and thoracic skin excess was also recorded for every subject, as well as clinical and surgical postoperative complications. A total number of 73 Caucasian underwent J-shaped brachioplasty. Our technique allowed us to treat both arm and thoracic skin excess with a single skin incision. Among our casuistic we had only two cases of postoperative bleeding and four cases of partial wound dehiscence due to tension. Seroma was reported only in one (female) patient. Despite the recent introduction our technique has proven to reach good results in massive weight loss patients.
- Published
- 2018
- Full Text
- View/download PDF
48. The role of Interdisciplinary Teams in Physical and Rehabilitation Medicine.
- Author
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Singh R, Küçükdeveci AA, Grabljevec K, and Gray A
- Subjects
- Humans, Health Personnel standards, Patient Care Team standards, Physical and Rehabilitation Medicine methods
- Abstract
The increasing complexity of healthcare provision and medical interventions requires collaboration between large numbers of health professionals. The nature of the interactions between team members determines whether the pattern of working is described as multi-, inter- or trans-disciplinary. Such team-working is an important part of the specialty of Physical and Rehabilitation Medicine. Grounded in group behaviour theory, team-working demonstrates that joint aims, trust and willingness to share knowledge, can improve patient outcomes, including mortality. The synthesis of individual skills and knowledge and working to common patient goals, has shown benefit in many conditions. This evidence base is perhaps best in stroke, but has been demonstrated in many other conditions, including acquired brain injury, back pain, mental health, cardiopulmonary conditions, chronic pain and hip fracture. There are also considerable benefits to staff and health organizations in terms of outcome and staff morale. This review paper examines the evidence for the benefit of such team-working and for the recommendations of team-working in rehabilitation services.
- Published
- 2018
- Full Text
- View/download PDF
49. Strengthening rehabilitation services in Indonesia: A brief situation analysis.
- Author
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Nugraha B, Setyono GR, Defi IR, and Gutenbrunner C
- Subjects
- Humans, Indonesia, Disabled Persons rehabilitation, Health Services Accessibility standards
- Abstract
People with disability (PWD) in Indonesia are often neglected by society. Improving their life situation towards full participation in society is crucial. As a health strategy, rehabilitation can improve func-tioning, quality of life and participation in society. However, rehabilitation services in Indonesia need improvement. Making a situation analysis of rehabilitation services and their provision in the country is a pre-requisite to taking any action towards improvement. This paper compiles available data related to disability and rehabilitation services in Indonesia, using the Rehabilitation Services Assessment Tool (RSAT) as a framework. Gaps in provision were analysed, resulting in the compilation of a list of generic recommendations to improve rehabilitation services in the country. Indonesia faces many challenges in rehabilitation services, including the health workforce and the provision of services. This situation analysis and list of generic recommendations may be used in further discussions with relevant stakeholders in the country to develop a national strategy to strengthen rehabilitation services.
- Published
- 2018
- Full Text
- View/download PDF
50. Strengthening health-related rehabilitation services at national levels.
- Author
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Gutenbrunner C, Bickenbach J, Melvin J, Lains J, and Nugraha B
- Subjects
- Humans, Disabled Persons rehabilitation, Rehabilitation standards, World Health Organization organization & administration
- Abstract
Objective: One of the aims of the World Health Organization's Global Disability Action Plan is to strengthen rehabilitation services. Some countries have requested support to develop (scale-up) rehabilitation services. This paper describes the measures required and how (advisory) missions can support this purpose, with the aim of developing National Disability, Health and Rehabilitation Plans., Recommendations: It is important to clarify the involvement of governments in the mission, to define clear terms of reference, and to use a systematic pathway for situation assessment. Information must be collected regarding policies, health, disability, rehabilitation, social security systems, the need for rehabilitation, and the existing rehabilitation services and workforce. Site visits and stakeholder dialogues must be done. In order to develop a Rehabilitation Service Implementation Framework, existing rehabilitation services, workforce, and models for service implementation and development of rehabilitation professions are described. Governance, political will and a common understanding of disability and rehabilitation are crucial for implementation of the process. The recommendations of the World Report on Disability are used for reporting purposes., Conclusion: This concept is feasible, and leads to concrete recommendations and proposals for projects and a high level of consensus stakeholders.
- Published
- 2018
- Full Text
- View/download PDF
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