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1. [About the antimicrobial activity of substituted aromatic aldehydes (author's transl)].

Author

Rehn D, Nolte H, and Zerling W

Subjects
Chemical Phenomena, Chemistry, Drug Resistance, Microbial, Microbial Sensitivity Tests, Species Specificity, Aldehydes pharmacology, Bacteria drug effects, Benzaldehydes pharmacology, Fungi drug effects
Abstract

The MIC-values and the antimicrobial activity in the paper disc diffusion method of 86 resp. 79 substituted aromatic aldehydes have been investigated. Antibacterial activity has been tested against Staphylococcus aureus, Pseudomonas aeruginosa, Proteus vulgaris and Klebsiella pneumoniae, the antifungal activity against Trichophyton mentagrophytes, Aspergillus niger and Candida albicans. 13 classes of substituents have been investigated. The most active compounds are substituted with nitro-, hydroxy- and halogen groups.

Published
1981