31 results on '"Zanger, Ulrich M."'
Search Results
2. ABCC11/MRP8 polymorphisms affect 5-fluorouracil-induced severe toxicity and hepatic expression
3. Abundance of DNA adducts of methyleugenol, a rodent hepatocarcinogen, in human liver samples
4. Novel CYP2B6 Enzyme Variants in a Rwandese Population: Functional Characterization and Assessment of In Silico Prediction Tools
5. Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
6. PPARA: A Novel Genetic Determinant of CYP3A4 In Vitro and In Vivo
7. Inferring statin-induced gene regulatory relationships in primary human hepatocytes
8. Inferring statin-induced gene regulatory relationships in primary human hepatocytes
9. Expression of Organic Cation Transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) Is Affected by Genetic Factors and Cholestasis in Human Liver†
10. Pharmacogenomics of human liver cytochrome P450 oxidoreductase: multifactorial analysis and impact on microsomal drug oxidation
11. 6-Mercaptopurine and 9-(2-Phosphonyl- Methoxyethyl) Adenine (PMEA) Transport Altered by Two Missense Mutations in the Drug Transporter Gene ABCC4
12. Non-synonymous polymorphisms in the human SLCO1B1 gene: an in vitro analysis of SNP c.1929A>C
13. Polymorphic CYP2B6: molecular mechanisms and emerging clinical significance
14. Impact of CYP2B6 polymorphism on hepatic efavirenz metabolism in vitro
15. Sex-dependent genetic markers of CYP3A4 expression and activity in human liver microsomes
16. Three Novel Thiopurine S-Methyltransferase Allelic Variants (TPMT*20, *21, *22) - Association With Decreased Enzyme Function
17. Cytochrome P450 2B6 activity as measured by bupropion hydroxylation: Effect of induction by rifampin and ethnicity
18. Interindividual variability of canalicular ATP-binding-cassette (ABC)–transporter expression in human liver
19. Thiopurine Methyltransferase (TPMT) Genotype and Early Treatment Response to Mercaptopurine in Childhood Acute Lymphoblastic Leukemia
20. Limited association of the 2988G>A single nucleotide polymorphism with CYP2D6*41 in black subjects
21. Inhibition of human CYP2B6 by N,N′,N″-triethylenethiophosphoramide is irreversible and mechanism-based
22. A novel intronic mutation, 2988G>A, with high predictivity for impaired function of cytochrome P450 2D6 in white subjects
23. Large interindividual variability in the in vitro formation of tamoxifen metabolites related to the development of genotoxicity
24. Polymorphisms of the dihydropyrimidine dehydrogenase and the thymidilate synthase genes in relation to severe toxicity of treatment with 5-fluorouracil: A prospective multicenter study
25. The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver
26. Genetic polymorphisms of glutathione S-transferase A1, the major glutathione S-transferase in human liver: Consequences for enzyme expression and busulfan conjugation
27. Distribution of microsomal epoxide hydrolase in humans: An immunohistochemical study in normal tissues, and benign and malignant tumours
28. Microsomal Epoxide Hydrolase Expression as a Predictor of Tamoxifen Response in Primary Breast Cancer: A Retrospective Exploratory Study With Long-Term Follow-Up
29. Immunohistochemical detection of microsomal epoxide hydrolase in human synovial tissue
30. Transcriptional profiling of genes induced in the livers of patients treated with carbamazepine
31. The involvement of CYP1A2 and CYP3A4 in the metabolism of clozapine
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