38 results on '"Yeo, Giles"'
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2. Hypothalamic loss of Snord116 recapitulates the hyperphagia of Prader-Willi syndrome
3. Contributions of Function-Altering Variants in Genes Implicated in Pubertal Timing and Body Mass for Self-Limited Delayed Puberty
4. A coding variant in FTO confers susceptibility to thiopurine-induced leukopenia in East Asian patients with IBD
5. Impaired prohormone processing: a grand unified theory for features of Prader-Willi syndrome?
6. High fat diet impairs the function of glucagon-like peptide-1 producing L-cells
7. TCR usage, gene expression and function of two distinct FOXP3+Treg subsets within CD4+CD25hi T cells identified by expression of CD39 and CD45RO
8. FTO Obesity Variant and Adipocyte Browning in Humans
9. NFIX Regulates Proliferation and Migration Within the Murine SVZ Neurogenic Niche
10. LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal
11. Low Circulating Levels of IGF-1 in Healthy Adults Are Associated With Reduced β-Cell Function, Increased Intramyocellular Lipid, and Enhanced Fat Utilization During Fasting
12. The bigger picture of FTO—the first GWAS-identified obesity gene
13. The hypothalamus and metabolism: integrating signals to control energy and glucose homeostasis
14. Overlap of Endocrine Hormone Expression in the Mouse Intestine Revealed by Transcriptional Profiling and Flow Cytometry
15. FTO and Obesity: A Problem for a Billion People
16. From GWAS to biology: lessons from FTO
17. The expression of dynein light chain DYNLL1 (LC8-1) is persistently downregulated in glaucomatous rat retinal ganglion cells
18. Prevalence of Loss-of-Function FTO Mutations in Lean and Obese Individuals
19. A deletion of the HBII-85 class of small nucleolar RNAs (snoRNAs) is associated with hyperphagia, obesity and hypogonadism
20. Functional Characterization and Structural Modeling of Obesity Associated Mutations in the Melanocortin 4 Receptor
21. Serotonin 5-HT2C Receptor Agonist Promotes Hypophagia via Downstream Activation of Melanocortin 4 Receptors
22. The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase
23. Hyperphagia, Severe Obesity, Impaired Cognitive Function, and Hyperactivity Associated With Functional Loss of One Copy of the Brain-Derived Neurotrophic Factor (BDNF) Gene
24. Leptin Deficiency Unmasks the Deleterious Effects of Impaired Peroxisome Proliferator–Activated Receptor γ Function (P465L PPARγ) in Mice
25. Proopiomelanocortin-Deficient Mice Are Hypersensitive to the Adverse Metabolic Effects of Glucocorticoids
26. The Effects of Proopiomelanocortin Deficiency on Murine Adrenal Development and Responsiveness to Adrenocorticotropin
27. Studies of the Peptide YY and Neuropeptide Y2 Receptor Genes in Relation to Human Obesity and Obesity-Related Traits
28. Proopiomelanocortin and Energy Balance: Insights from Human and Murine Genetics
29. Genetic Variants in Human Sterol Regulatory Element Binding Protein-1c in Syndromes of Severe Insulin Resistance and Type 2 Diabetes
30. Deletion of Codons 88-92 of the Melanocortin-4 Receptor Gene: A Novel Deleterious Mutation in an Obese Female
31. Minireview: Human Obesity--Lessons from Monogenic Disorders
32. Binge Eating as a Phenotype of Melanocortin 4 Receptor Gene Mutations
33. Contribution of Variants in the Small Heterodimer Partner Gene to Birthweight, Adiposity, and Insulin Levels: Mutational Analysis and Association Studies in Multiple Populations
34. Clinical Spectrum of Obesity and Mutations in the Melanocortin 4 Receptor Gene
35. Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms
36. A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism
37. Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency
38. The CART Gene and Human Obesity: Mutational Analysis and Population Genetics
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